NCS-MPP (4-(2′-METHOXY-PHENYL)-1-[2′-(N-2″-PYRIDYL)-P-Isothiocyanobenzamido]-Ethyl-Piperazine): A high affinity and irreversible 5-HT1A receptor ligand

Life Sciences

Volumn 58, Issue 3, 1995, Pages 177-186

  Kung, Mei Ping ^a   Mu, Mu ^a   Zhuang, Zhi Ping ^a   Kung, Hank F ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

homogenate binding; irreversible inactivation; radioiodinated ligand

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 4 IODO N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)BENZAMIDE; 4 ISOTHIOCYANATO N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)BENZAMIDE; 8 HYDROXY 2 [N (3 IODO 2 PROPENYL) N PROPYLAMINO]TETRALIN; IODINE 125; N [(1 ETHYL 2 PYRROLIDINYL)METHYL] 3 IODO 5,6 DIMETHOXYSALICYLAMIDE; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; SPIPERONE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; HIPPOCAMPUS; NONHUMAN; RAT; RECEPTOR AFFINITY;

ANIMALS; BENZAMIDES; HIPPOCAMPUS; ISOTHIOCYANATES; KINETICS; MOLECULAR STRUCTURE; RADIOLIGAND ASSAY; RATS; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1;

ANIMALIA;

EID: 0030045457     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/0024-3205(95)02275-9     Document Type: Article

References (40)

1. Derivatives of 4-(2'-Methoxyphenyl)-1-[2'-(N-2''-pyridinyl-p-iodobenzamido)ethyl]piperazine (p-MPPI) as 5-HT1A Ligands