The Human Growth Hormone (hGH) Antagonist G120RhGH Does Not Antagonize GH in the Rat, But Has Paradoxical Agonist Activity, Probably Via the Prolactin Receptor

Endocrinology

Volumn 137, Issue 2, 1996, Pages 447-454

  Mode, Agneta ^a   Tollet, Petra ^a   Wells, Timothy ^b   Carmignac, Danielle F ^b   Clark, Ross G ^c   Chen, Wen Y ^d   Kopchick, John J ^d   Robinson, Iain C A F ^b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^c GENENTECH INC   (United States)

^d OHIO UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE ANTAGONIST; GROWTH HORMONE RECEPTOR; HUMAN GROWTH HORMONE; PROLACTIN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; DIMERIZATION; FEMALE; GROWTH HORMONE BLOOD LEVEL; GROWTH HORMONE DEFICIENCY; GROWTH HORMONE RELEASE; HORMONAL REGULATION; HORMONE RECEPTOR INTERACTION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; PULSATILE FLOW; RAT; RECEPTOR BLOCKING; SPECIES DIFFERENCE;

ANIMALS; CELLS, CULTURED; DWARFISM; GROWTH HORMONE; HOMOZYGOTE; HUMANS; HYPOPHYSECTOMY; INJECTIONS, INTRAVENOUS; INJECTIONS, SUBCUTANEOUS; LIVER; MALE; PROLACTIN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PROLACTIN; RECOMBINANT PROTEINS;

EID: 0030045426     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.2.8593788     Document Type: Article

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