메뉴 건너뛰기




Volumn 117, Issue 3, 1996, Pages 573-579

The effects of anticonvulsants on 4-aminopyridine-induced bursting: In vitro studies on rat peripheral nerve and dorsal roots

Author keywords

Action potentials; Aminopyridines (4 AP); Carbamazepine; Dorsal roots; Electrophysiology; Lamotrigine; Multiple sclerosis; Phenytoin; Rat sciatic nerve; Toxicity

Indexed keywords

4 AMINOPYRIDINE; ANTICONVULSIVE AGENT; CARBAMAZEPINE; LAMOTRIGINE; PHENYTOIN;

EID: 0030045193     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15229.x     Document Type: Article
Times cited : (10)

References (40)
  • 2
    • 0027478416 scopus 로고
    • An in vitro study of focal epileptogenesis in combined hippocampal-parahippocampal slices
    • BEAR, J. & LOTHMAN, E.W. (1993). An in vitro study of focal epileptogenesis in combined hippocampal-parahippocampal slices. Epilepsy Res., 14, 183-93.
    • (1993) Epilepsy Res. , vol.14 , pp. 183-193
    • Bear, J.1    Lothman, E.W.2
  • 3
    • 0025318536 scopus 로고
    • Preliminary trial of 3,4-diaminopyridine in patients with multiple sclerosis
    • BEVER, JR, C.T., LESLIE, J., CAMENGA, D.L., PANITCH, H.S. & JOHNSON, K.P. (1990). Preliminary trial of 3,4-diaminopyridine in patients with multiple sclerosis. Ann. Neurol., 27 (4), 421-427.
    • (1990) Ann. Neurol. , vol.27 , Issue.4 , pp. 421-427
    • Bever Jr., C.T.1    Leslie, J.2    Camenga, D.L.3    Panitch, H.S.4    Johnson, K.P.5
  • 4
    • 0025162044 scopus 로고
    • Ion channel organization of the myelinated fibre
    • BLACK, J.A., KOCSIS, J.D. & WAXMAN, S.G. (1990). Ion channel organization of the myelinated fibre. Trends Neurosci., 13, 48-54.
    • (1990) Trends Neurosci. , vol.13 , pp. 48-54
    • Black, J.A.1    Kocsis, J.D.2    Waxman, S.G.3
  • 5
    • 0021891177 scopus 로고
    • Activity dependent excitability changes in normal and demyelinated rat spinal root axons
    • BOSTOCK, H. & GRAFF., P. (1985). Activity dependent excitability changes in normal and demyelinated rat spinal root axons. J. Physiol., 365, 239-57.
    • (1985) J. Physiol. , vol.365 , pp. 239-257
    • Bostock, H.1    Graff, P.2
  • 6
    • 0019391105 scopus 로고
    • The effects of 4-aminopyridine and tetraethylammonium ions on normal and demyelinated mammalian nerve fibres
    • BOSTOCK, H., SEARS, T.A. & SHERRATT, R.M. (1981). The effects of 4-aminopyridine and tetraethylammonium ions on normal and demyelinated mammalian nerve fibres. J. Physiol., 313, 301-305.
    • (1981) J. Physiol. , vol.313 , pp. 301-305
    • Bostock, H.1    Sears, T.A.2    Sherratt, R.M.3
  • 7
    • 0018154612 scopus 로고
    • Overcoming conduction failure in demyelinated nerve fibres by prolonging action potentials
    • BOSTOCK, H., SHERRATT, R.M. & SEARS, T.A. (1978). Overcoming conduction failure in demyelinated nerve fibres by prolonging action potentials. Nature, 274, 385-387.
    • (1978) Nature , vol.274 , pp. 385-387
    • Bostock, H.1    Sherratt, R.M.2    Sears, T.A.3
  • 8
    • 0023214855 scopus 로고
    • Physiological effects of 4-aminopyridine on demyelinated mammalian motor and sensory fibers
    • BOWE, C.M., KOCSIS, J.D., TARG, E.F. & WAXMAN, S.G. (1987). Physiological effects of 4-aminopyridine on demyelinated mammalian motor and sensory fibers. Ann. Neurol., 22, 264-268.
    • (1987) Ann. Neurol. , vol.22 , pp. 264-268
    • Bowe, C.M.1    Kocsis, J.D.2    Targ, E.F.3    Waxman, S.G.4
  • 9
    • 0023574096 scopus 로고
    • + channels: Local anaesthetics, antiarrythmics and anticonvulsants
    • + channels: local anaesthetics, antiarrythmics and anticonvulsants. Trends Pharmacol. Sci., 8, 57-65.
    • (1987) Trends Pharmacol. Sci. , vol.8 , pp. 57-65
    • Catterall, W.A.1
  • 10
    • 0026443902 scopus 로고
    • An in vitro investigation of the action of lamotrigine on neuronol voltage-activated sodium channels
    • CHEUNG, H., KAMP, D. & HARRIS, M. (1992). An in vitro investigation of the action of lamotrigine on neuronol voltage-activated sodium channels. Epilepsy Res., 13, 107-112.
    • (1992) Epilepsy Res. , vol.13 , pp. 107-112
    • Cheung, H.1    Kamp, D.2    Harris, M.3
  • 11
    • 0019391114 scopus 로고
    • Evidence for the presence of potassium channels in the paranodal region of acutely demyelinated mammalian single nerve fibres
    • CHIU, S.Y. & RITCHIE, J.M. (1981). Evidence for the presence of potassium channels in the paranodal region of acutely demyelinated mammalian single nerve fibres. J. Physiol., 313, 415-437.
    • (1981) J. Physiol. , vol.313 , pp. 415-437
    • Chiu, S.Y.1    Ritchie, J.M.2
  • 12
    • 0028112226 scopus 로고
    • Kainic acid and 4-aminopyridine seizure models in mice: Evaluation of efficacy of anti-epileptic agents and calcium antagonists
    • CRANMER, C.L., STAGNITTO, M.L., KNOWLES, M.A. & PALMER, G.C. (1994). Kainic acid and 4-aminopyridine seizure models in mice: evaluation of efficacy of anti-epileptic agents and calcium antagonists. Life-Sci., 54, 271-5.
    • (1994) Life-Sci. , vol.54 , pp. 271-275
    • Cranmer, C.L.1    Stagnitto, M.L.2    Knowles, M.A.3    Palmer, G.C.4
  • 13
    • 0025253455 scopus 로고
    • Orally administered 4-aminopyridine improves clinical signs in multiple sclerosis
    • DAVIS, F.A., STEFOSKI, D. & RUSH, J. (1990). Orally administered 4-aminopyridine improves clinical signs in multiple sclerosis. Ann. Neurol., 27, 186-192.
    • (1990) Ann. Neurol. , vol.27 , pp. 186-192
    • Davis, F.A.1    Stefoski, D.2    Rush, J.3
  • 14
    • 0024238517 scopus 로고
    • Development of 4-AP and TEA sensitivities in mammalian myelinated nerve fibres
    • ENG, D.L., GORDON, T.R., KOCSIS, J.D. & WAXMAN, S.G. (1988). Development of 4-AP and TEA sensitivities in mammalian myelinated nerve fibres. J. Neurophysiol., 60, 2168-2179.
    • (1988) J. Neurophysiol. , vol.60 , pp. 2168-2179
    • Eng, D.L.1    Gordon, T.R.2    Kocsis, J.D.3    Waxman, S.G.4
  • 15
    • 0026666306 scopus 로고
    • Effects of antiepileptic drugs on 4-aminopyridine-induced epileptiform activity in young and adult rat hippocampus
    • FUETA, Y. & AVOLI, M. (1992). Effects of antiepileptic drugs on 4-aminopyridine-induced epileptiform activity in young and adult rat hippocampus. Epilepsy Res., 12, 207-15.
    • (1992) Epilepsy Res. , vol.12 , pp. 207-215
    • Fueta, Y.1    Avoli, M.2
  • 16
    • 0016847243 scopus 로고
    • Sodium flux, action potential and temperature dependence
    • GOLDMAN, L., HAHIN, R. & BEGENISICH, T. (1975). Sodium flux, action potential and temperature dependence. Nature, 257, 516-517.
    • (1975) Nature , vol.257 , pp. 516-517
    • Goldman, L.1    Hahin, R.2    Begenisich, T.3
  • 17
    • 0028215297 scopus 로고
    • Variant firing patterns in rat hippocampal pyramidal cells modulated by extracellular potassium
    • JENSEN, M.S., AZOUZ, R. & YAARI, Y. (1994). Variant firing patterns in rat hippocampal pyramidal cells modulated by extracellular potassium. J. Neurophysiol., 71, 831-9.
    • (1994) J. Neurophysiol. , vol.71 , pp. 831-839
    • Jensen, M.S.1    Azouz, R.2    Yaari, Y.3
  • 18
    • 9044232688 scopus 로고
    • Research directed towards understanding MS- An overview
    • JOHNS, T. & BERNARD, C. (1994). Research directed towards understanding MS- an overview. Mult. Scler. News, 156, 24-26.
    • (1994) Mult. Scler. News , vol.156 , pp. 24-26
    • Johns, T.1    Bernard, C.2
  • 20
    • 0028814685 scopus 로고
    • The effects of anticonvulsant compounds on 4-aminopyridine-induced de-novo synthesis of neurotransmitter amino acids in rat hippocampus in vitro
    • KAPETANOVIC, I.M., YONEKAWA, I.M. & KUPFERBERG, H.J. (1995). The effects of anticonvulsant compounds on 4-aminopyridine-induced de-novo synthesis of neurotransmitter amino acids in rat hippocampus in vitro. Epilepsy Res., 20, 113-20.
    • (1995) Epilepsy Res. , vol.20 , pp. 113-120
    • Kapetanovic, I.M.1    Yonekawa, I.M.2    Kupferberg, H.J.3
  • 21
    • 0027507511 scopus 로고
    • Lamotrigine, phenytoin and carbamezepine interactions on the sodium current present in N4TG1 mouse neuroblastoma cells
    • LANG, D.G., WANG, C.M. & COOPER, B.R. (1993). Lamotrigine, phenytoin and carbamezepine interactions on the sodium current present in N4TG1 mouse neuroblastoma cells. J. Pharmacol. Exp. Ther., 266, 829-835.
    • (1993) J. Pharmacol. Exp. Ther. , vol.266 , pp. 829-835
    • Lang, D.G.1    Wang, C.M.2    Cooper, B.R.3
  • 22
    • 0027310109 scopus 로고
    • Studies on the mechanism of action of the novel anticonvulsant lamotrigine (Lamictal) using primary neuroglial cultures from rat cortex
    • LEES, G. & LEACH, M.J. (1993). Studies on the mechanism of action of the novel anticonvulsant lamotrigine (Lamictal) using primary neuroglial cultures from rat cortex. Brain Res., 612, 190-199.
    • (1993) Brain Res. , vol.612 , pp. 190-199
    • Lees, G.1    Leach, M.J.2
  • 23
    • 0022565563 scopus 로고
    • Anticonvulsant drugs: Mechanisms of action
    • MACDONALD, R.L. & MCLEAN, M.J. (1986). Anticonvulsant drugs: mechanisms of action. Ad. Neurol., 44, 713-736.
    • (1986) Ad. Neurol. , vol.44 , pp. 713-736
    • Macdonald, R.L.1    McLean, M.J.2
  • 25
    • 0019476136 scopus 로고
    • Treatment with oral 4-aminopyridine in disorders of neuromuscular transmission
    • MURRAY, N.M.F. & NEWSOM-DAVIS, J. (1981). Treatment with oral 4-aminopyridine in disorders of neuromuscular transmission. Neurology (Ny), 31, 265-271.
    • (1981) Neurology (Ny) , vol.31 , pp. 265-271
    • Murray, N.M.F.1    Newsom-Davis, J.2
  • 27
    • 9044243219 scopus 로고
    • Clinical research and trials-looking at clinical trials of new therapeutic agents and research to develop treatments for MS
    • REINGOLD, S. (1994). Clinical research and trials-looking at clinical trials of new therapeutic agents and research to develop treatments for MS. Mult. Scler. News, 156, 17-18.
    • (1994) Mult. Scler. News , vol.156 , pp. 17-18
    • Reingold, S.1
  • 28
    • 0024456476 scopus 로고
    • Heterogeneous distribution of fast and slow potassium channels in myelinated rat nerve fibres
    • ROPER, J. & SCHWARZ, J.R. (1989). Heterogeneous distribution of fast and slow potassium channels in myelinated rat nerve fibres. J. Physiol., 416, 93-110.
    • (1989) J. Physiol. , vol.416 , pp. 93-110
    • Roper, J.1    Schwarz, J.R.2
  • 29
    • 0025643437 scopus 로고
    • Axolemmal abnormalities in myelin mutants
    • ROSENBLUTH, J. (1990). Axolemmal abnormalities in myelin mutants. Ann. N.Y. Acad. Sci., 605, 194-214.
    • (1990) Ann. N.Y. Acad. Sci. , vol.605 , pp. 194-214
    • Rosenbluth, J.1
  • 30
    • 84987058300 scopus 로고
    • Mode of action of insecticidal dihydropyrazoles: Selective block of impulse generation in sensory nerves
    • SALGADO, V.L. (1990). Mode of action of insecticidal dihydropyrazoles: selective block of impulse generation in sensory nerves. Pestic. Sci., 28, 389-411.
    • (1990) Pestic. Sci. , vol.28 , pp. 389-411
    • Salgado, V.L.1
  • 31
    • 0023265707 scopus 로고
    • + channels to 4-aminopyridine and TEA
    • + channels to 4-aminopyridine and TEA. Experientia, 43, 405-408.
    • (1987) Experientia , vol.43 , pp. 405-408
    • Schauf, C.L.1
  • 32
    • 0023193088 scopus 로고
    • Amantadine restores impulse conduction across demyelinated nerve segments
    • SCHAUF, C.L. (1987b). Amantadine restores impulse conduction across demyelinated nerve segments. Clin. Exp. Pharmacol. Physiol., 14, 273-281.
    • (1987) Clin. Exp. Pharmacol. Physiol. , vol.14 , pp. 273-281
    • Schauf, C.L.1
  • 33
    • 0015970873 scopus 로고
    • Impulse conduction in multiple sclerosis: A theoretical basis for modification by temperature and pharmacological agents
    • SCHAUF, C.L. & DAVIS, F.A. (1974). Impulse conduction in multiple sclerosis: a theoretical basis for modification by temperature and pharmacological agents. J. Neurol. Neurosurg. Psychiatry, 37, 152-161.
    • (1974) J. Neurol. Neurosurg. Psychiatry , vol.37 , pp. 152-161
    • Schauf, C.L.1    Davis, F.A.2
  • 34
    • 0023134727 scopus 로고
    • 4-Aminopyridine improves clinical signs in multiple sclerosis
    • STEFOSKI, D., DAVIS, F.A., FAUT, M. & SCHAUE, C.L. (1987). 4-Aminopyridine improves clinical signs in multiple sclerosis. Ann. Neurol., 21, 71-77.
    • (1987) Ann. Neurol. , vol.21 , pp. 71-77
    • Stefoski, D.1    Davis, F.A.2    Faut, M.3    Schaue, C.L.4
  • 36
    • 0021922832 scopus 로고
    • 4-Aminopyridine leads to restoration of conduction in demyelinated rat sciatic nerve
    • TARG, E.F. & KOCSIS, J.D. (1985). 4-Aminopyridine leads to restoration of conduction in demyelinated rat sciatic nerve. Brain Res., 328, 358-361.
    • (1985) Brain Res. , vol.328 , pp. 358-361
    • Targ, E.F.1    Kocsis, J.D.2
  • 38
    • 0027476884 scopus 로고
    • Effects of carbamazepine and baclofen on 4-aminopyridine-induced epileptic activity in rat hippocampal slices
    • WATTS, A.E. & JEFFRYS, J.G. (1993). Effects of carbamazepine and baclofen on 4-aminopyridine-induced epileptic activity in rat hippocampal slices. Br. J. Pharmacol., 108, 819-23.
    • (1993) Br. J. Pharmacol. , vol.108 , pp. 819-823
    • Watts, A.E.1    Jeffrys, J.G.2
  • 39
    • 0019760585 scopus 로고
    • Clinicopathological correlations in multiple sclerosis and related diseases
    • WAXMAN, S.G. (1981). Clinicopathological correlations in multiple sclerosis and related diseases. Adv. Neurol., 31, 169-182.
    • (1981) Adv. Neurol. , vol.31 , pp. 169-182
    • Waxman, S.G.1
  • 40
    • 0026608653 scopus 로고
    • Effects of anticonvulsant drugs on 4-aminopyridine-induced seizures in mice
    • YAMAGUCHI, S. & ROGAWSKI, M.A. (1992). Effects of anticonvulsant drugs on 4-aminopyridine-induced seizures in mice. Epilepsy Res., 11, 9-16.
    • (1992) Epilepsy Res. , vol.11 , pp. 9-16
    • Yamaguchi, S.1    Rogawski, M.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.