Comet assay studies indicate that caffeine-mediated increase in radiation risk of embryos is due to inhibition of DNA repair

Mutagenesis

Volumn 11, Issue 1, 1996, Pages 57-60

  Muller W U ^a   Bauch, T ^a   Wojcik, A ^a   Bocker W ^a   Streffer, C ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE;

ANIMAL CELL; ARTICLE; BLASTOMERE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA REPAIR; EMBRYO; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIATION HAZARD;

ANIMALS; CAFFEINE; CENTRAL NERVOUS SYSTEM STIMULANTS; DNA; DNA DAMAGE; DNA REPAIR; EMBRYO; FEMALE; MICE; MUTAGENS; PREGNANCY; RISK FACTORS;

EID: 0030044594     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/11.1.57     Document Type: Article

References (32)

1. Boynton,A.L., Evans,T.C. and Crouse,D.A. (1974) Effects of caffeine on radiation-induced mitotic inhibition in S-180 Ascites tumor cells. Radiat, Res., 60, 89-97.
2. Brinster,R.L. (1969) Mammalian embryo culture. In Hafez,E.S.E. and Blandau,R.J. (eds), The Mammalian Oviduct. University of Chikago Press, Chicago, IL, pp. 419-444
3. 2 arrest. Radiat. Res., 76, 292-307.
4. Fairbairn,D.W., Olive,P.L. and O'Neill,K.L. (1995) The comet assay: a comprehensive review. Mutat. Res., 339, 37-59.
5. Jung,T. and Streffer,C. (1991) Association of protein phosphorylation and cell cycle progression after X-irradiation of two-cell mouse embryos. Int. J. Radiat. Biol., 60, 511-523.
6. Kihlman,B.A., Sturehd,S., Hartley-Asp,B. and Nilsson,K. (1974) The enhancement by caffeine of the frequencies of chromosomal aberrations induced in plant and animal cells by chemical and physical agents. Mutat. Res., 26, 105-122.
7. Kihlman,B.A. (1977) Caffeine and Chromosomes. Elsevier, Amsterdam.
8. Kimler,B.F., Leeper,D.B., Snyder,M.H., Rowley,R. and Schneiderman,M.H. (1982) Modification of radiation-induced division delay by caffeine analogues and dibutyrylcyclic AMP. Int. J. Radiat. Biol., 41, 47-58.
9. Lang,H. (1975) Model for repair inhibition by caffeine. Studia Biophys., 50, 213-221.
10. Lehmann,A.R. (1972) Effect of caffeine on DNA synthesis in mammalian cells. Biophys. J., 12, 1316-1325.
11. 2 delay: a period of cell recovery. Radiat. Res., 89, 298-308.
12. 2 arrest increases the yield of chromosome aberrations. Int. J. Radiat. Biol., 43, 123.
13. Marticorena,P., Hogan,B., DiMeo,A., Artzt,K. and Bennett,D. (1983) Carbohydrate changes in pre- and peri-implantation mouse embryos as detected by a monoclonal antibody. Cell Diff., 12, 1-10.
14. McKelvey-Martin,V.J., Green,M.H.L., Schmezer,P., Pool-Zobel,B.L., De Méo,M.P. and Collins,A. (1993) The single cell gel electrophoresis assay (comet assay): a European review. Mutat. Res., 288, 47-63.
15. Müller,W.-U. (1989) Toxiciry of various combinations of X-rays, caffeine and mercury in mouse embryos. Int. J. Radiai. Biol., 56, 315-323.
16. 3H-thymidine or ultraviolet light in combination with caffeine. Teratogen. Carcinogen. Mutagen., 6, 107-114.
17. Müller, W.-U., Streffer,C. and Fischer-Lahdo,C. (1983) Effects of a combination of X-rays and caffeine on preimplantation mouse embryos in vitro. Radiat. Environ. Biophys., 22, 85-93.
18. Muller,W.-U., Streffer,C and Wurm,R. (1985) Supraadditive formation of micronuclei in preimplantation mouse embryos in vitro after combined treatment with X-rays and caffeine. Teratogen. Carcinogen. Mutagen., 5, 123-131.
19. Müller,W-U., Kasper,C and Streffer.C (1993) Relation between rate of cell proliferation and formation of micronuclei after combined treatment with X-rays and caffeine. Radiai. Environ. Biophys., 32, 239-249.
20. Müller,W.-U., Bauch,T., Streffer,C., Niedercichholz,F. and Bocker,W. (1994) Comet assay studies of radiation-induced DNA damage and repair in various tumour cell lines. Int. J Radiat. Biol., 65, 315-319.
21. Ostling,O. and Johanson,K.J. (1984) Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells. Biochem. Biophys. Res. Commun., 123, 291-298.
22. Pamter,R.B. (1980) Effect of caffeine on DNA synthesis in irradiated and unirradiated mammalian cells. J. Mol Biol., 143, 289-301.
23. 2 delay. Int. J. Radiat. Biol., 19, 191-195.
24. Selby,C.P. and Sancar,A. (1990a) Mechanisms of caffeine inhibition of DNA repair in E.coli. Prog. Clin. Biol. Res., 340A, 179-193.
25. Selby,C.P. and Sancar,A, (1990b) Molecular mechanisms of DNA repair inhibition by caffeine. Proc. Natl Acad. Sci. USA. 87, 3522-3525.
26. Snyder,M.H., Kimler,B.F. and Leeper,D.B. (1977) The effect of caffeine on radiation-induced division delay. Int. J. Radiat. Biol., 32, 281-284.
27. Streffer,C. and Müller,W.-U. (1984) Radiation risk from combined exposures to ionizing radiations and chemicals. Adv. Radiat. Biol., 11, 173-210.
28. Timson,J. (1977) Caffeine. Mutat. Res., 47, 1-52.
29. Tolmach,L.J., Jones,R.W. and Busse,P.M. (1977) The action of caffeine on X-irradiared HeLa cells. I. Delayed inhibition of DNA synthesis. Radiat. Res., 71, 653-665.
30. Tomasovic,S.P. and Dewey,W.C. (1978) Comparative studies of the effects of drugs on X-ray-mduced G2 delay. Radiat. Res., 74, 112-128.
31. Waldren,C.A., Patlerson,D., Kato,H. and Rumsby,P. (1983) Nucleoside metabolism, caffeine and repair. In Nygaard,O.F. and Simic,M.G. (eds), Radioprotection and Anticarcinogens. Academic Press, New York.
32. Walters,R.A., Gurley,L.R. and Tobey,R.A. (1974) Effects of caffeine on radiation-induced phenomena associated with cell-cycle traverse of mammalian cells. Biophys. J., 14, 99-118.