Antibody-mediated inhibition of Aedes aegypti midgut trypsins blocks sporogonic development of Plasmodium gallinaceum

Infection and Immunity

Volumn 64, Issue 3, 1996, Pages 739-743

  Shahabuddin, Mohammed ^a   Lemos, Francisco J A ^b   Kaslow, David C ^a   Jacobs Lorena, Marcelo ^b  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRYPSIN;

AEDES AEGYPTI; ANTIBODY DETECTION; ANTIBODY RESPONSE; ARTICLE; DISEASE TRANSMISSION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; MALARIA; MIDGUT; NONHUMAN; PLASMODIUM GALLINACEUM; PRIORITY JOURNAL; SPOROGENESIS;

EID: 0030044285     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.3.739-743.1996     Document Type: Article

References (17)

1. Barillas-Mury, C., R. Graf, H. H. Hagedorn, and M. Wells. 1991. cDNA and deduced amino acid sequence of a blood meal-induced trypsin from the mosquito, Aedes aegypti. Insect Biochem. 21:825-831.
2. Clements, A. N. 1992. Adult digestion, p. 272-291. In The biology of mosquitoes, vol. 1. Chapman & Hall, Cambridge.
3. Graf, R., and H. Briegel. 1982. Comparison between aminopeptidase and trypsin activity in blood-fed female Aedes aegypti. Rev. Suisse Zool. 89:815-850.
4. Graf, R., A. S. Raikhel, and M. R. Brown. 1986 Mosquito trypsin: immunocytochemical localization in the midgut of blood-fed Aedes aegypti (L). Cell Tissue Res. 245:19-27.
5. Grotendorst, C. A., and R. Carter. 1987. Complement effects the infectivity of Plasmodium gallinaceum to Aedes aegypti mosquitoes. II Changes in sensitivity to complement-like factors during zygote development. J. Parasitol. 73:980-984.
6. Huber, M., E. Cabib, and L. H. Miller. 1990. Malaria parasite chitinase and penetration of the mosquito peritrophic membrane Proc. Natl. Acad. Sci USA 88:2807-2810
7. Kalhok, S. E., L. M. Tabak, D. E. Presser, W. Brook, A. E. R. Downe, and B. N. White. 1993. Isolation, sequencing and characterization of two cDNA clones coding for trypsin-like enzymes from the midgut of Aedes aegypti Insect Mol. Biol. 2:71-79.
8. Kaushal, U. C., R. Carter, J. Rener, C. A. Grotendorst, L. H. Miller, and R. J. Howard. 1983. Monoclonal antibodies against surface determinants on gametes of Plasmodium gallinaceum block transmission of malaria parasites to mosquitoes. J. Immunol. 131:2557-2562.
9. Lehane, M. J. 1991. Transmission of parasites by blood-sucking insects, p 143-192 In Biology of the blood-sucking insects. Harper Collins Academic. London
10. Muller, H. M., J. M. Crampton, A. Torre, R. Sinden, and A. Crisanti. 1993 Members of the trypsin gene family in Anopheles gambiae are induced in the gut by blood meal. EMBO J. 12:2891-2900.
11. Ramos, A., A. Mahowald, and M. Jacobs-Lorena. 1993. Gut-specific genes from the black fly Simulium vittatum encoding trypsin-like and carboxypeptidase-like proteins. Insect Mol. Biol. 1:149-163.
12. Rosenberg, R., L. C. Koontz, K. Alston, and F. K. Friedman. 1984. Plasmodium gallinaceum: erythrocyte factor essential for zygote infection of Aedes aegypti. Exp. Parasitol 57:158-164.
13. Shahabuddin, M., M. Criscio, and D. C. Kaslow. 1995. Unique specificity of in vitro inhibition of mosquito midgut trypsin-like activity correlates with in vivo inhibition of malaria parasite infectivity. Exp Parasitol. 80:212-219.
14. Shahabuddin, M., and D. C. Kaslow. 1994. Biology of the development of Plasmodium in the mosquito midgut A molecular and cellular view. Bull. Inst. Pasteur 92:119-132.
15. Shahabuddin, M., T. Toyoshima, M. Aikawa, and D. C. Kaslow. 1993. Transmission-blocking activity of a chitinase inhibitor and activation of malarial parasite chitinase by mosquito protease. Proc Natl. Acad. Sci USA 90:4266-4270.
16. Shahabuddin, M., et al. Unpublished data.
17. Sieber, K. P., M. Huber, D. C. Kaslow, S. M. Banks, M. Torii, M. Aikawa, and L. H. Miller. 1991. The peritrophic membrane as a barrier, its penetration by Plasmodium gallmaceum and the effect of a monoclonal antibody to ookinetes. Exp. Parasitol. 72:145-156.