Presymptomatic diagnosis in Portuguese FAP families using intragenic RFLPs and (CA)n flanking markers by fluorescence based semiautomated DNA analysis

Journal of Medical Genetics

Volumn 33, Issue 3, 1996, Pages 244-247

  Almeida, Rosário ^a   Fidalgo, Paulo ^b   Ramalho, Eunice ^b   Brás, Aldina ^a   Leitão, Nobre ^b   Mira, Costa ^b   Rueff, José ^a   Monteiro, Carolino ^a  

^a NOVA MEDICAL SCHOOL   (Portugal)

^b Department of Gastroenterology   (Portugal)

Author keywords

Familial adenomatous polyposis; Fluorescence technology; Pre symptomatic diagnosis

Indexed keywords

DNA; DNA MARKER;

ADENOMATOUS POLYP; ARTICLE; CLINICAL ARTICLE; DNA DETERMINATION; DNA FLANKING REGION; FAMILY STUDY; FEMALE; FLUORESCENCE ANALYSIS; GENE LOCATION; GENE LOSS; GENE SEGREGATION; GENETIC SCREENING; HAPLOTYPE; HUMAN; HUMAN CELL; MALE; PORTUGAL; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT;

ADENOMATOUS POLYPOSIS COLI; AUTOMATION; DNA; FEMALE; GENES, APC; GENETIC MARKERS; GENOTYPE; HAPLOTYPES; HUMANS; INTRONS; MALE; PEDIGREE; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PORTUGAL; REPETITIVE SEQUENCES, NUCLEIC ACID; RISK ASSESSMENT;

EID: 0030044077     PISSN: 00222593     EISSN: None     Source Type: Journal    
DOI: 10.1136/jmg.33.3.244     Document Type: Article

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