Angiotensin converting enzyme (ACE) inhibitor-induced cough and substance P

Thorax

Volumn 51, Issue 2, 1996, Pages 199-201

  Tomaki, Masafumi ^a   Ichinose, Masakazu ^a   Miura, Motohiko ^a   Hirayama, Yoshitaka ^b   Kageyama, Natsuko ^a   Yamauchi, Hideyuki ^a   Shirato, Kunio ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b ASTELLAS PHARMA INC   (Japan)

Author keywords

ACE inhibitor; Neurogenic inflammation; Substance P

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; SUBSTANCE P;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; DRUG EFFECT; HUMAN; HYPERTENSION; INFLAMMATION; MALE; NEUROLOGIC DISEASE; PRIORITY JOURNAL; RADIOIMMUNOASSAY; SPUTUM ANALYSIS;

EID: 0030043453     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.51.2.199     Document Type: Article

References (8)

1. Hood S, Nicholls MG, Gilcrist NL. Cough with converting enzyme inhibitors. NZ Med J 1987;100:6-7.
2. Barnes PJ, Baraniuk JN, Belvisi MG. Neuropeptides in the respiratory tract: part II. Am Rev Respir Dis 1991;144: 1391-9.
3. Ichinose M, Barnes PJ. The effect of peptidase inhibitors on bradykinin-induced bronchoconstriction in guinea-pigs in vivo. Br J Phamacol 1990;101:77-80.
4. Kohrogi H, Graf PD, Sekizawa K, Borson DB, Nadel JA. Neutral endopeptidase inhibitors potentiate substance P-and capsaicin-induced cough in awake guinea pigs. J Clin Invest 1988;82:2063-8.
5. Pin I, Gibson PG, Kolendowicz R, Girgis-Gabardo A, Denburg JA, Hargreave FE, et al. Use of induced sputum cell counts to investigate airway inflammation in asthma. Thorax 1992;47:25-9.
6. Tomaki M, Ichinose M, Miura M, Hirayama Y, Yamauchi H, Nakajima N, et al. Elevated substance P content in induced sputum from patients with asthma and patients with chronic bronchitis. Am J Respir Crit Care Med 1995; 151:613-7.
7. Umeno E, Mcdonald DM, Nadel JA. Hypertonic saline increases vascular permeability in the rat trachea by producing neurogenic inflammation. J Clin Invest 1990;85: 1905-8.
8. Ichinose M, Nakajima N, Takahashi T, Yamauchi H, Inoue H, Takishima T. Protection against bradykinin-induced bronchoconstriction in asthmatic patients by neurokinin receptor antagonist. Lancet 1992;340:1248-1.