Epithelial modulation of cholinergic responses in rabbit trachea is partly due to neutral endopeptidase activity

European Journal of Pharmacology

Volumn 296, Issue 1, 1996, Pages 89-96

  Loenders, Brigitte ^a   Jorens, Philippe G ^a   Herman, Arnold G ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Acetylcholine; Cholinergic neurotransmission; Epithelium; Neutral endopeptidase; Rabbit; Trachea

Indexed keywords

ACETYLCHOLINE; CAPSAICIN; CARBACHOL; ENKEPHALINASE INHIBITOR; INDOMETACIN; ISO OMPA; MEMBRANE METALLOENDOPEPTIDASE; N(G) NITROARGININE METHYL ESTER; NEOSTIGMINE; NITRIC OXIDE SYNTHASE; PHOSPHORAMIDON; POSTSYNAPTIC RECEPTOR; POTASSIUM CHLORIDE; PROSTAGLANDIN; PROTEINASE INHIBITOR;

ACETYLCHOLINE RELEASE; ANIMAL TISSUE; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CHOLINERGIC TRANSMISSION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTROSTIMULATION; INFLAMMATION; NONHUMAN; PRESYNAPTIC INHIBITION; PRIORITY JOURNAL; RABBIT; SMOOTH MUSCLE CONTRACTION; TRACHEA MUCOSA; TRACHEA MUSCLE;

EID: 0030042573     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(95)00681-8     Document Type: Article

References (41)

1. Allegra, L., L.M. Fabbri, G. Picotti and S. Mattoli, 1989, Bronchial epithelium and asthma, Eur. Respir. J. 2, Suppl. 6, 460s.
2. Atack, J.A., Q.-S. Yu, T.T. Soncrant, A. Brossi, S.J. Rapoport, 1989, Comparative inhibitory effects of various physostigmine analogs against acetyl-and butyrylcholinesterases, J. Pharmacol. Exp. Ther. 249, 194.
3. Barnes, P.J., 1986, Neural control of human airways in health and disease, Am. Rev. Respir. Dis. 134, 1289.
4. Barnett, K., D.B. Jacoby, J.A. Nadel and S.C Lazarus, 1988, The effects of epithelial cell supernatant on contractions of isolated canine tracheal smooth muscle, Am. Rev. Respir. Dis. 138, 780.
5. Bertrand, C. and E. Tschirhart, 1993, Epithelial factors: modulation of the airway smooth muscle tone, Fundam. Clin. Pharmacol. 7, 261.
6. Burgaud, J.L., J. Javellaud and N. Oudart, 1993, Do perfused small caliber airways of guinea-pig release an epithelium-dependent relaxing factor?, Pulm. Pharmacol. 6, 217.
7. Butler, G.B., K.B. Adler, J.N. Evans, D.W. Morgan and J.L. Szarek, 1987, Modulation of rabbit airway smooth muscle responsiveness by respiratory epithelium, Am. Rev. Respir. Dis. 135, 1099.
8. Damsma, G., D. Lammerts van Bueren, B.H.C. Westerink and A.S. Horn, 1987, Determination of acetylcholine and choline in the femtomole range by means of HPLC, a post-column enzyme reactor and electrochemical detection, Chromatographia 24, 827.
9. Deckers, I.A. and A.G. Herman, 1988, HPLC detection of acetylcholine released from canine airway segments, Pflügers Arch. (Eur. J. Physiol.) 412, S42.
10. Deckers, I.A., M. Rampart, H. Bult and A.G. Herman, 1989, Evidence for the involvement of prostaglandins in modulation of acetylcholine release from canine bronchial tissue, Eur. J. Pharmacol. 167, 415.
11. Di Maria, G.V., M. Katayama, D.B. Borson and J.A. Nadel, 1992, Neutral endopeptidase modulates endothelin-1-induced airway smooth muscle contraction in guinea-pig trachea, Reg. Pept. 39, 137.
12. Dusser, D.J., E. Umeno, P.D. Graf, T. Djokic, D.B. Borson and J.A. Nadel, 1988, Airway neutral endopeptidase-like enzyme modulates tachykinin-induced bronchoconstriction in vivo, J. Appl. Physiol. 65, 2585.
13. Dusser, D.J., D.B. Jacoby, T.D. Djokic, I. Rubinstein, D.B. Borson and J.A. Nadel, 1989, Virus induces airway hyperresponsiveness to tachykinins: role of neutral endopeptidase, J. Appl. Physiol. 67, 1504.
14. Farmer, S.G., J.S. Fedan, D.W.P. Hay and D. Raeburn, 1986, The effects of epithelium removal on the sensitivity of guinea-pig isolated trachealis to bronchodilator drugs, Br. J. Pharmacol. 89, 407.
15. Fernandez, L.B., J.W. Paterson and R.G. Goldie, 1989, Co-axial bioassay of a smooth muscle relaxant factor released from guinea-pig tracheal epithelium, Br. J. Pharmacol. 96, 117.
16. GüC, M.O., M. Ilhan and S.O. Kayaalp, 1988, The rat anococcygeus muscle is a convenient bioassay organ for the airway epithelium-derived relaxant factor, Eur. J. Pharmacol. 148, 405.
17. Hay, D.W.P., S.G. Farmer, D. Raeburn, V.A. Robinson, W.W. Fleming and J.S. Fedan, 1986, Airway epithelium modulates the reactivity of guinea-pig respiratory smooth muscle, Eur. J. Pharmacol. 129, 11.
18. Hay, D.W.P., D. Raeburn and J.S. Fedan, 1987, Regional differences in reactivity and in the influence of the epithelium on canine intrapulmonary bronchial smooth muscle responsiveness, Eur. J. Pharmacol. 141, 363.
19. Hogg, J.C. and P.A. Eggleston, 1984, Is asthma an epithelial disease?, Am. Rev. Respir. Dis. 129, 207.
20. Holroyde, M.C., 1986, The influence of epithelium on the responsiveness of guinea-pig isolated trachea, Br. J. Pharmacol. 87, 501.
21. Inoue, K., Y. Sakai and I. Homma, 1992, An ubiquitous modulating function of rabbit tracheal epithelium: degradation of tachykinins, Br. J. Pharmacol. 105, 393.
22. Kilbinger, H., R. Schneider, H. Siefken, D. Wolf and G. D'Agostino, 1991, Characterization of prejunctional muscarinic autoreceptors in the guinea pig trachea, Br. J. Pharmacol. 103, 1757.
23. Koga, Y., S. Satoh, N. Sodeyama, Y. Hashimoto, T. Yanagisawa and Hirshman C.A., 1992, Role of acetylcholinesterase in airway epithelium inhibition of acetylcholine-induced contraction of guinea-pig isolated trachea, Eur. J. Pharmacol. 220, 141.
24. Laitinen, L.A., M. Heino, A. Laitinen, T. Kava and T. Haahtela, 1985, Damage of the airway epithelium and bronchial reactivity in patients with asthma, Am. Rev. Respir. Dis. 131, 599.
25. Lev, A., G.C. Christensen, R. Zhang and S.G. Kelsen, 1990, Epithelial effects on tracheal smooth muscle tone: influence of muscarinic antagonists, Am. J. Physiol. 258, L52.
26. Lindström, E.G., R.G.G. Andersson, G. Granérus, N. Grundström, 1991, Histamine receptors, distribution and metabolism: Is the airway epithelium responsible for histamine metabolism in the trachea of guinea-pigs?, Agents Actions 33, 170.
27. Loenders, B., M. Rampart and A.G. Herman, 1992, Selective M3 muscarinic receptor antagonists inhibit smooth muscle contraction in rabbit trachea without increasing the release of acetylcholine, J. Pharmacol. Exp. Ther. 263, 773.
28. Minette, P.A., J.W. Lammers, C.M. Dixon, M.T. McCusker and P.J. Barnes, 1989, A muscarinic agonist inhibits reflex bronchoconstriction in normal but not in asthmatic subjects, J. Appl. Physiol. 67, 2461.
29. Morrison, K.J., Y. Gao and P.M. Vanhoutte, 1990, Epithelial modulation of airway smooth muscle, Am. J. Physiol. 258, L254.
30. Murlas, C., 1986, Effects of mucosal removal on guinea-pig airway smooth muscle responsiveness, Clin. Sci. 70, 571.
31. Raeburn, D., D.W.P. Hay, V.A. Robinson, S.G. Farmer, W.W. Fleming and J.S. Fedan, 1986, The effect of verapamil is reduced in isolated airway smooth muscle preparations lacking the epithelium, Life Sci. 38, 809.
32. Sakai, Y., K. Inoue and I. Homma, 1993, Relations of contractile hyperreactivity to tachykinins in rabbit trachea, Reg. Pept. 46, 233.
33. Sekizawa, K., J. Tamaoki, J.A. Nadel and D.B. Borson, 1987, Enkephalinase inhibitor potentiates substance P-induced and electrically induced contraction in ferret trachea, J. Appl. Physiol. 63, 1401.
34. Small, R.C., D.M. Good, J.S. Dixon and I. Kennedy, 1990, The effects of epithelium removal on the actions of cholinomimetic drugs in opened segments and perfused tubular preparations of guinea-pig trachea, Br. J. Pharmacol. 100, 516.
35. Solway, J. and A.G. Leff, 1991, Sensory neuropeptides and airway function, J. Appl. Physiol. 71, 2077.
36. Spina, D. and C.P. Page, 1991, The release of a non-prostanoid inhibitory factor from rabbit bronchus detected by co-axial bioassay, Br. J. Pharmacol. 102, 896.
37. Tanaka, D.T. and M.M. Grunstein, 1984, Mechanisms of substance P-induced contraction of rabbit airway smooth muscle, J. Appl. Physiol. 57, 1551.
38. Tanaka, D.T. and M.M. Grunstein, 1986, Effect of substance P on neurally mediated contraction of rabbit airway smooth muscle, J. Appl. Physiol. 60, 458.
39. Ullman, A., C.-G. Löfdahl, N. Svedmyr and B.-E. Skoogh, 1990, Nerve stimulation releases mucosa-derived inhibitory factors, both prostanoids and nonprostanoids, in isolated ferret trachea, Am. Rev. Respir. Dis. 141, 748.
40. Vanhoutte, P.M., 1988, Epithelium-derived relaxing factor(s) and bronchial reactivity, Am. Rev. Respir. Dis. 138, S24.
41. 3H] acetylcholine release from the isolated guinea-pig trachea, Naunyn-Schmied. Arch. Pharmacol. 342, 387.