Therapy of Bacterial Vaginosis Using Exogenously-Applied Lactobacilli acidophili and a Low Dose of Estriol: A placebo-controlled multicentric clinical trial

Arzneimittel-Forschung/Drug Research

Volumn 46, Issue 1, 1996, Pages 68-73

  Parent, Dominique ^a   Bossens, Michel ^b   Bayot, Dominique ^c   Kirkpatrick, Christine ^a   Graf, Federico ^d   Wilkinson, Fay E ^d   Kaiser, Renato R ^d  

^a ERASME HOSPITAL   (Belgium)

^b Hôpital d'Ixelles   (Belgium)

^c Intensive Care Unit   (Belgium)

^d Medinova Ltd   (Switzerland)

Author keywords

Bacterial vaginosis, diagnosis; CAS 50 27 1; Estriol; Gynoflor , clinical studies, placebo controlled; Lactobacilli acidophili

Indexed keywords

ESTRIOL; GYNOFLOR; PLACEBO; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; HUMAN; INTRAVAGINAL DRUG ADMINISTRATION; LACTOBACILLUS ACIDOPHILUS; MULTICENTER STUDY; PHARMACEUTICS; RANDOMIZED CONTROLLED TRIAL; TABLET; VAGINA FLORA; VAGINITIS;

ADULT; AGED; COMBINED MODALITY THERAPY; DOUBLE-BLIND METHOD; ESTRIOL; FEMALE; HUMANS; LACTOBACILLUS ACIDOPHILUS; MIDDLE AGED; VAGINA; VAGINOSIS, BACTERIAL;

EID: 0030042556     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Amsel, A. R., Totten, P. A., Spiegel, C. A. et al., Am. J. Med. 74, 14 (1983)
2. Gardner, H. L., Dukes, C. D., Am. J. Obstet. Gynecol. 69, 962 (1955)
3. Gardner, H. L., Dukes, C. D., Ann. N. Y. Acad. Sci. 83, 280 (1959)
4. Holmes, K. K., Spiegel, C. A., Amsel, A. R. et al., Scand. J. Infect. Dis. 26, 110 (1981)
5. Mardh, P. A., Rev. Fr. Gynecol. Obstet. 88, 195 (1993)
6. Ison, C. A., Dawson, S. G., Hilton, J. et al., J. Clin. Pathol. 35, 550 (1982)
7. Spiegel, C. A., Amsel, A. R., Eschenbach, D. A. et al., N. Engl. J. Med. 303, 601 (1980)
8. Martius, J., in: Vulvovaginitis, P. Elsner, J. Martius (eds.), Chapter 14, Marcel Dekker, Inc., New York (1993)
9. Highlights from the Third International Symposium on Vaginitis/Vaginosis, Madeira, Portugal, February 1994
10. Eschenbach, D. A., Hiller, S. L., Critchlow, C. et al., Am. J. Obstet. Gynecol 158, 819 (1988)
11. McCutchan, J. A., Ronald, A. R., Corey, L. et al., in: European Guidelines for the Clinical Evaluation of Anti-Infective Drug Products, T. R. Beam Jr., C. N. Gilbert, D. M. Kunin (eds.), pp. 140-148, European Society of Clinical Microbiology and Infectious Diseases (1993)
12. Delcroix, M., Infections Gynécologiques, p. 175, Masson, Paris (1994)
13. Spiegel, C. A., Amsel, A. R., Holmes, K. K., J. Clin. Microbiol. 18, 170 (1983)
14. Mazzuli, T., Simor, A. E., Low, D. E. et al., J. Clin. Microbiol. 28, 1506 (1990)
15. Nugent, R. P., Krohn, M. A., Hillier, S. L., J. Clin. Microbiol. 29, 297 (1991)
16. Fredricsson, B., Nord, C. E., Scand. J. Infect. Dis. 40, (Suppl.), 91 (1983)
17. Eschenbach, D. A., Davick, P. R., Williams, B. L. et al., J. Clin. Microbiol. 27, 251 (1989)
18. Sweet, R. L., Am. J. Obstet. Gynecol. 169, 479 (1993)
19. Fischbach, F., Petersen, E. E., Weissenbacher, E. R., Obstet. Gynecol. 82, 405 (1993)
20. Barefoot, S. F. Klaenhammer, T. R., Appl. Environ. Microbiol. 45, 1808 (1983)
21. Redondo-Lopez, V., Cook, R. L., Sobel, J. D., Rev. Infect. Dis. 12, 856 (1990)
22. Nagy, E., Petterson, M., Mardh, P. A., APMIS 99, 739 (1991)
23. Spiegel, C. A., Clin. Microbiol. Rev. 4, 485 (1991)
24. Gerstner, G. L., Müller, G., Gynäkol. Rundsch. 27, 71 (1987)
25. Kanne, B., Patz, B., Wackerle, L., Frauenarzt 3, 35 (1986)
26. Overman, B. A., J. Nurse Midwifery 38, 146 (1993)
27. Hallen, A., Jarstrand, C. Pahlson, C., Sex. Transm. Dis. 19, 146 (1992)
28. Bach, C., Nurse Pract. 17, 9 (1992)
29. Hilton, E., Isenberg, H. D., Alperstein, P., Ann. Intern. Med. 116, 353 (1992)
30. Saling, E., Brandt-Niebelschutz, S., Schmitz, C., Z. Geburtsh. Perinatol. 195, 209 (1991)
31. Kanne, B., Jenny, J., Gynäkol. Rundsch. 31, 7 (1991)
32. Fredricsson, B., Englund, K., Weintraub, L. et al., Gynecol. Obstet. Invest. 28, 156 (1989)
33. Hughes, V. L., Hillier, S. L., Obstet. Gynecol. 75, 244 (1990)