Direct spinal projections to limbic and striatal areas: Anterograde transport studies from the upper cervical spinal cord and the cervical enlargement in squirrel monkey and rat

Journal of Comparative Neurology

Volumn 365, Issue 4, 1996, Pages 640-658

  Newman, Heike M ^a   Stevens, Richard T ^a   Apkarian, A Vania ^a  

^a SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

Author keywords

anterograde tracing; biotin dextran; spinoamygdaloid; spinohypothalamic; spinotelencephalic

Indexed keywords

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CERVICAL SPINAL CORD; CONTROLLED STUDY; GENETIC ORGANIZATION; LIMBIC CORTEX; NERVE FIBER TRANSPORT; NOCICEPTION; NONHUMAN; PAIN; PERCEPTION; PRIORITY JOURNAL; RECEPTIVE FIELD; SPINOTHALAMIC TRACT; SQUIRREL MONKEY; STRIATE CORTEX;

EID: 0030042518     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(19960219)365:4<640::AID-CNE10>3.0.CO;2-L     Document Type: Article

References (52)

1. Abercrombie, M. (1966) Estimation of nuclear population from microtome sections. Anat. Rec. 94:239-247.
2. Albert, D.J., and G.L. Chew (1980) The septal forebrain and the inhibitory modulation of attack and defense in the rat. A review. Behav. Neural Biol. 30:357-388.
3. Apkarian, A.V. (1995) Functional imaging of pain: New insights regarding the role of the cerebral cortex in human pain perception. Sem. Neurosci., 7:279-293.
4. Apkarian, A.V., and C.J. Hodge (1989a) The primate spinothalamic pathways. I. A quantitative study of the cells of origin of the spmothalamic pathway. J. Comp. Neurol. 288:447-473.
5. Apkarian, A.V., and C.J. Hodge (1989b) The primate spinothalamic pathways: III. Thalamic terminations of the dorsolateral and ventral spinothalamic pathway. J. Comp. Neurol. 288:403-511.
6. Applegate, M.D., D.S. Kerr, and P W. Landfield (1987) Redistribution of synaptic vesicles during longterm potentiation in the hippocampus. Brain Res. 401:401-406.
7. Bernard, J.F., G.F. Huang, and J.M. Besson (1992) Nucleus centralis of the amygdala and the globus pallidus ventralis: Electrophysiological evidence for an involvement in pain processes. J. Neurophysiol 68:551-569.
8. Block, C.H., G. Hoffman, and B.S. Kapp (1989) Peptide-containing pathways from the parabrachial complex to the central nucleus of the amygdala Peptides 10:465-171
9. Brandt, H.M., and A.V. Apkarian (1992) Biotin-dextran: A sensitive antero-grade tracer for neuroanatomic studies in rat and monkey. J. Neurosci. Meth. 45:35-40.
10. Burstein, R., and G.J. Giesler, Jr. (1989) Retrograde labeling of neurons in spinal cord that project directly to nucleus accumbens or the septal nuclei in the rat. Brain Res. 497:149-154.
11. Burstein, R , and S. Potrebic (1993) Retrograde labeling of neurons in the spinal cord that project directly to the amygdala or the orbital cortex in the rat. J. Comp Neurol 335:469-485
12. Burstein, R , K.D Cliffer, and G.J. Giesler, Jr. (1987) Direct somatosensory projections from the spinal cord to the hypothalamus and telencephalon. J. Neurosci. 7:4159-4164
13. Burstein, R. K.D Cliffer, and G.J. Giesler, Jr. (1990a) Cells of origin of the spinohypothalamic tract in the rat. J. Comp. Neurol 291:329-344.
14. Burstein, R., R. J Dado, and G.J. Giesler, Jr. (1990b) The cells of origin of the spinothalamic tract of the rat: A quantitative reexamination. Brain Res. 511:329-337
15. Chang, H -T., and T.C. Ruch (1949) Spmal origin of the ventral supraoptic decussation (Gudden's commissure) in the spider monkey J Anat. 83:1-9.
16. Chudler, E.H., and WK. Dong (1995) The role of the basal ganglia in nociception and pam. Pain 60:3-38
17. Chudler, E.H., K. Sugiyama, and W.K. Dang (1993) Nociceptive responses in the neostriatum and globus pallidus of the anesthetized rat. J. Neurophysiol. 69:1890-1903.
18. Cliffer, K.D, R. Burstein, and G.J. Giesler, Jr. (1991) Distributions of spinothalamic, spinohypothalamic and spinotelencephalic fibers revealed by anterograde transport of PHA-L in rats. J. Neurosci. 11:852-868.
19. Craig, A.D., and H. Burton (1985) The distribution and topographical organization in the thalamus of anterogradely-transported horseradish peroxidase after spinal injections in cat and raccoon. Exp. Brain Res. 58:227-254.
20. Dado, R.J., J.T. Katter, and G.J. Giesler, Jr. (1994a) Spinothalamic and spinohypothalamic tract neurons in the cervical enlargement of rats. II. Responses to innocuous and noxious mechanical and thermal stimuli. J. Neurophysiol. 71.981-1002.
21. Dado, E.J., J.T Katter, and G.J. Giesler, Jr. (1994b) Spinothalamic and spinohypothalamic tract neurons in the cervical enlargement of rats. III. Locations of antidromically identified axons in the cervical cord white matter. J Neurophysiol. 71:1003-1021.
22. DeLong, M.R., M.D. Crutcher, and A P. Georgopoulos (1985) Primate globus pallidus and subthalamic nucleus, functional organization. J. Neurophysiol. 53:530-543.
23. Desmond, N.L., and W.B. Levy (1990) Morphological correlates of long-term potentiation imply the modification of existing synapses, not synaptogenesis, in the hippocampal dentate gyrus, Synapse 5:139-143.
24. Emmers, R., and K. Akert (1963) A Stereotaxic Atlas of the Brain of the Squirrel Monkey (Saimiri sciureus) Madison: University of Wisconsin Press.
25. Gardner, E., and H.M. Cuneo (1945) Lateral spinothalamic tract and associated tracts in man. Arch Neurol. 53:423-430.
26. Henneman, E. (1957) Relation between size of neurons and their susceptibility to discharge. Science 126:1345-1347.
27. Hodge, C.J., and A.V. Apkarian (1990) The spinothalamic tract. Neurobiology 5:363-397.
28. Hori, T , T Kiyohara, Y. Oomura, H. Nishino, S. Aou, and I Fujita (1987) Activity of thermosensitive neurons of monkey preoptic hypothalamus during thermoregulatory operant behavior. Brain Res. Bull 18:649-655.
29. Hylden, J.L.K., H. Hayashi, G.J. Bennett, and R. Dubner (1985) Spinal lamina I neurons projecting to the parabrachial area of the cat midbrain. Brain Res. 336:195-198
30. Kai, Y., Y. Oomura, and N. Shimizu (1988) Responses of rat lateral hypothalamic neurons to periaqueductal gray stimulation and nociceptive stimuli. Brain Res. 461:107-117
31. Katter, J.T., R. Burstein, and G.J. Giesler, Jr. (1991) The cells of origin of the spinohypothalamic tract in cats. J. Comp. Neurol. 303:101-112.
32. Kerr, F.W.L., and H.H. Lippman (1974) The primate spinothalamic tract as demonstrated by anterolateral cordotomy and commissural myelotomy. Adv. Neurol. 4:147-156
33. Kuru, M. (1949) Sensory Paths in the Spinal Cord and Brainstem in Man. Tokyo: Sogensya.
34. Lima, D , and A Coimbra (1988) The spinothalamic system of the rat: Structural types of retrogradely labelled neurons in the marginal zone (lamina I) Neuroscience 27:215-230.
35. Ma, W., and M. Peschanski (1988) Spinal and trigeminal projections to the parabrachial nucleus in the rat. Electron-microscopic evidence of a spino-ponto-amygdalian somatosensory pathway. Somatosens. Res. 5:247-257.
36. Mantyh, P.W. (1983) The spinothalamic tract in the primate: A reexamination using wheatgerm agglutinin conjugated to horseradish peroxidase. Neuroscience 9.847-862.
37. Matsushita, M , and H. Yaginuma (1990) Afferents to the cerebellar nuclei from the cervical enlargement in the rat, as demonstrated with the Phaseolus vulgaris leucoagglutinin method. Neurosci. Lett. 113:253-259.
38. McKenna, J.E., and K. Melzack (1994) Bilateral VB thalamotomy does not reduce pain in the formalin test. Soc. Neurosci. Abstr. 20:1572.
39. Nicolelis, M.A., J K. Chapin, and R.C. Lin (1992) Somatotopic maps within zona incerta relay parallel GABAergic pathways to the neocortex, superior colliculus, and brainstem. Brain Res. 571:134-141.
40. Parrent, A.G., A.M. Lozano, J.O Dostrovsky, and S.E. Tasker (1992) Central pain in the absence of functional sensory thalamus. Stereotact. Funct. Neurosurg 59:9-14.
41. Saper, C.B , and A.D. Loewy (1980) Efferent connections of the parabrachial nucleus in the rat. Brain Res. 197:291-317.
42. Slugg, R.M., and A.R. Light (1994) Spinal cord and trigeminal projections to the pontine parabrachial region in the rat as demonstrated with Phaseo lus vulgaris leucoagglutinin. J. Comp. Neurol. 339:49-61.
43. Smith, M V., A.V. Apkarian, and C.J. Hodge (1991) Somatosensory response properties of contralaterally projecting spinothalamic and nonspinothalamic neurons in the second cervical segment of the cat. J Neurophysiol. 66:83-102.
44. Smith, Y., L. Hazrati, and A. Parent (1990) Efferent projections of the subthalamic nucleus in the squirrel monkey as studied by the PHA-L anterograde tracing method. J. Comp. Neurol. 294:306-323.
45. Swanson, L.W (1992) Brain Maps: Structure of the Rat Brain. Amsterdam: Elsevier
46. Vogt, B.A., R.W. Sikes, and L.J. Vogt (1993) Anterior cingulate cortex and the medial pain system. In B.A. Vogt and M. Gabriel (eds): Neurobiology of Cingulate Cortex and Limbic Thalamus: A Comprehensive Handbook. Boston: Birkháuser, pp. 313-344.
47. Walker, A.E. (1940) The spinothalamic tract in man. Arch. Neurol Psychiat. 43:284-298
48. Willis, W.D. Jr. (1985) Nociceptive pathways: Anatomy and physiology of nociceptive ascending pathways. Phil. Trans. R Soc. Lond. 308:235-268.
49. Wouterlood, F.G., B. Jorritsma-Byham, and P.H. Goede (1990) Combination of anterograde tracing with Phaseolus vulgaris-leueoagghitinin, retro-grade fluorescent tracing and fixed-slice intracellular injection of lucifer yellow. J. Neurosci. Meth. 33:207-217.
50. Yamamoto, T., R. Matsuo, Y. Kiyomitsu, and R. Kitamura (1989) Response properties of lateral hypothalamus neurons during ingestive behavior with special reference to licking various taste solutions. Brain Res 481:286-297.
51. Yeow, M.B.L., and E.H. Peterson (1991) Active zone organization and vesicle content scale with bouton size at a vertebrate central synapse J. Comp. Neurol. 307:475-486.
52. Zhang, X , E. Kostarczyk, and G.J. Giesler, Jr (1994) Spinohypothalamic tract neurons in the cervical enlargement of rats. Location of antidromically identified axons in the ipsilateral brain. Soc. Neurosci. Abstr. 20-547.