Microemulsion formulation of cyclosporine in pediatric liver transplantation

Transplantation

Volumn 61, Issue 3, 1996, Pages 512-514

  Alberti, Daniele ^a   Wallemacq, Pierre ^b   Falchetti, Diego ^a   De Ville De Goyet, Jean ^b   Rigamonti, Waifro ^a   Panzali, Anna ^a   Sokal, Etienne ^b   Otte, Jean Bernard ^b   Reding, Raymond ^b  

^a UNIVERSITY OF BRESCIA   (Italy)

^b CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A;

ARTICLE; CASE REPORT; CHILD; DIARRHEA; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG FORMULATION; FEMALE; HUMAN; INTESTINE RESECTION; LIVER FAILURE; LIVER TRANSPLANTATION; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; BIOLOGICAL AVAILABILITY; CHILD; CHILD, PRESCHOOL; CHOLESTASIS; CHRONIC DISEASE; CYCLOSPORINE; DIARRHEA; EMULSIONS; FEMALE; GRAFT REJECTION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTESTINAL ABSORPTION; LIVER TRANSPLANTATION; SHORT BOWEL SYNDROME;

EID: 0030042323     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199602150-00035     Document Type: Article

References (10)

1. Kahan BD. Cyclosporine. N Engl J Med 1989; 321: 1725.
2. Ptachcinski RJ, Venkataramanan R, Burckart GJ. Clinical pharmacokinetics of cyclosporin. Clin Pharmacokinet 1986; 11: 107.
3. Mueller EA, Kovarik JM, van Bree JB, Lison AE, Kutz K. Pharmacokinetics and tolerability of a microemulsion formulation of cyclosporine in renal allograft recipients: a concentration-controlled comparison with the commercial formulation. Transplantation 1994; 57: 1178.
4. Trull AK, Tan KC, Uttridge J, Bauer T, Alexander GJM, Jamieson NV. Cyclosporin absorption from microemulsion formulation in liver transplant recipient. Lancet 1993; 341: 433.
5. Kattner A, Winkler M, Oldhafer K, et al. Conversion from CyA to CyA-NOF in a cholestatic liver grafted patient with CyA malabsorption. Transplant Proc 1994; 26: 2975.
6. Whitington PF, Emond JC, Whitington SH, Broelsch CE, Baker AL. Small-bowel length and the dose of cyclosporine in children after liver transplantation. N Engl J Med 1990; 322: 733.
7. Cakaloglu Y, Marinos G, Marsden J, Peters TJ, Williams R, Tredger JM. Localization of cyclosporin A absorption in rat small bowel and the effect of bile. Clin Sci 1993; 84: 675.
8. Kehrer BH, Whitington PF, Black DD. The effect of Roux-en-Y biliary enterostomy on the absorption of cyclosporine: relevance to poor drug bioavailability in children after orthotopic liver transplantation. Transplant Proc 1988; 20: 523.
9. Demetris AJ, Fung JJ, Todo S, et al. Conversion of liver allograft recipients from cyclosporine to FK 506 immunosuppressive therapy: a clinicopathologic study of 96 patients. Transplantation 1992; 53: 1056.
10. Reding R, Wallemacq P, Lamy ME, et al. Conversion from cyclosporine A to FK 506 for salvage of immunocompromised pediatric liver allografts: efficacy, toxicity and dose regimen in 23 children. Transplantation 1994; 57: 93.