Neostigmine, atropine, and glycopyrrolate: Does neostigmine cross the placenta?

Anesthesiology

Volumn 84, Issue 2, 1996, Pages 450-452

  Clark, Richard B ^a,c   Brown, Mark A ^a   Lattin, Danny L ^b  

^a Department of Clinical and Health Psychology   (United States)

^b College of Pharmacy ^*

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Anesthesia; obstetric; atropine; glycopyrrolate; neostigmine; placental transfer

Indexed keywords

ANESTHETIC AGENT; ATROPINE; GLYCOPYRRONIUM BROMIDE; HALOPERIDOL; ISOFLURANE; LORAZEPAM; NEOSTIGMINE; NITROUS OXIDE; SUXAMETHONIUM; THIOPENTAL; VECURONIUM;

ADULT; ANESTHETIC RECOVERY; ARTICLE; CASE REPORT; ELBOW FRACTURE; FEMALE; FETUS HEART RATE; GENERAL ANESTHESIA; HUMAN; INHALATIONAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; OPEN REDUCTION; PARANOID SCHIZOPHRENIA; PLACENTAL TRANSFER; PRIORITY JOURNAL; UTERUS CONTRACTION;

ADJUVANTS, ANESTHESIA; ADULT; ANESTHESIA, GENERAL; ATROPINE; FEMALE; FETAL HEART; GLYCOPYRROLATE; HUMANS; MATERNAL-FETAL EXCHANGE; NEOSTIGMINE; PREGNANCY; PREGNANCY COMPLICATIONS;

EID: 0030041707     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199602000-00026     Document Type: Article

References (12)

1. Hon EH, Bradfield AH, Hess OW: The electronic evaluation of the fetal heart rate: V. The vagal factor in fetal bradycardia. Am J Obstet Gynecol 1961; 82:291-300
2. Proakis AG, Harris GB: Comparative penetration of glycopyrrolate and atropine across the blood-brain and placental barriers in anesthetized dogs. ANESTHESIOLOGY 1978; 48:339-44
3. Briggs CG, Freeman RK, Yaffe JJ: A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 3rd edition. Baltimore, Williams & Wilkins, 1990, pp 446-7
4. McNall PG, Jafarnia MR: Management of myasthenia in the obstetrical patient Am J Obstet Gynecol 1965; 92:518-25
5. Chambers DC, Hall JE, Boyce J: Myasthenia gravis and pregnancy. Obstet Gynecol 1967; 29:597-603
6. Plauché WC: Myasthenia gravis in pregnancy: An update. Am J Obstet Gynecol 1979; 135:691-7
7. Eden RD, Gall SA: Myasthenia gravis and pregnancy: A reappraisal of thymectomy. Obstet Gynecol 1983; 62:328-33
8. Herman NL: The placenta: Anatomy, physiology, and transfer of drugs, Obstetric Anesthesia: Principles and Practice. Edited by Chestnut DH. St. Louis, Mosby, 1994, pp 70-1
9. Mirkin BL: Drug distribution in pregnancy. Fetal Pharmacology. Edited by Boreus L. New York, Raven, 1973, pp 1-26
10. Roberts JB, Thomas BH, Wilson A: Placental transfer of pyridostigmine in the rat. Br J Pharmacol 1970; 38:202-5
11. Shnider SM, Levinson G: Anesthesia for Obstetrics. 3rd edition. Baltimore, Williams & Wilkins, 1993, p 275
12. James FM: Pharmacology of anesthetics. Clin Obstet Gynecol 1981; 24:517