Surface localization, regulation, and biologic properties of the 96-kDa alcohol/ aldehyde dehydrogenase (EhADH2) of pathogenic Entamoeba histolytica

Journal of Infectious Diseases

Volumn 173, Issue 1, 1996, Pages 226-231

  Flores, Becky M ^b   Stanley Jr , Samuel L ^b   Yong, Tai Soon ^b   Ali, Manzoor ^b   Yang, Wengang ^b   Diedrich, Dana L ^b   Torian, Bruce E ^a  

^a IDAHO STATE UNIVERSITY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; GENE PRODUCT; MEMBRANE ANTIGEN; MESSENGER RNA; MONOCLONAL ANTIBODY; PROTOZOAL PROTEIN; RIBONUCLEASE;

ANTIGEN DETECTION; ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; ENTAMOEBA HISTOLYTICA; ENZYME ASSAY; ENZYME REGULATION; IMMUNOBLOTTING; ISOTOPE LABELING; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PURIFICATION; RNA ANALYSIS; TROPHOZOITE;

EID: 0030041670     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/173.1.226     Document Type: Article

References (24)

1. Yang W, Li E, Kairong T, Stanley SL Jr. Entamoeba histolytica has an alcohol dehydrogenase homologous to the multifunctional adhE gene product of Escherichia coli. Mol Biochem Parasitol 1994;64:253-60.
2. Torian BE, Lukehart SA, Stamm WE. Use of monoclonal antibodies to identify, characterize, and purify a 96,000-dalton surface antigen of pathogenic Entamoeba histolytica. J Infect Dis 1987;156:334-43.
3. Torian BE, Reed SL, Flores BM, et al. The 96,000-dalton antigen as an integral membrane protein in pathogenic Entamoeba histolytica: potential difference in pathogenic and nonpathogenic isolates. Infect Immun 1990;58:753-60.
4. Torian BE, Reed SL, Flores BM, Plorde J, Stamm WE. Serologie response to the 96,000-Da surface antigen of pathogenic Entamoeba histolytica. J Infect Dis 1989;159:794-7.
5. Diamond LS, Harlow DR, Cunnick CC. A new medium for the axenic cultivation of Entamoeba histolytica and other Entamoeba. Trans R Soc Trop Med Hyg 1978;72:431-2.
6. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-5.
7. Flores BM, Reed SL, Ravdin JI, Torian BE. Serologic reactivity to purified recombinant and native 29-kilodalton peripheral membrane protein of pathogenic Entamoeba histolytica. J Clin Microbiol 1993;31:1403-7.
8. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins - from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979;76:4350-4.
9. Petri WA Jr, Chapman MD, Snodgrass T, Mann BJ, Browman J, Ravdin JI. Subunit structure of the galactose and N-acetyl-D-galactosamine-inhibitable adherence lectin of Entamoeba histolytica. J Biol Chem 1989;264:3007-12.
10. Tannich E, Bruchhause I, Walter RD, Horstmann RD. Pathogenic and nonpathogenic Entamoeba histolytica: identification and molecular cloning of an iron-containing Superoxide dismutase. Mol Biochem Parasitol 1991;49:61-72.
11. Petri WA Jr, Smith RD, Schlesinger PH, Murphy CF, Ravdin JI. Isolation of the galactose-binding lectin that mediates the in vitro adherence of Entamoeba histolytica. J Clin Invest 1987;80:1238-44.
12. Pancholi V, Fischetti VA. A major surface protein on group A streptococci is a glyceraldehyde-3-phosphate-dehydrogenase with multiple binding activity. J Exp Med 1992;176:415-26.
13. Pancholi V, Fischetti VA. Glyceraldehyde-3-phosphate dehydrogenase on the surface of group A streptococci is also an ADP-ribosylating enzyme. Proc Natl Acad Sci USA 1993;90:8154-8.
14. Goudot-Crozel V, Caillol D, Djabali M, Dessein AJ. The major parasite surface antigen associated with human resistance to schistosomiasis is a 37-kD glyceraldehyde-3P-dehydrogenase. J Exp Med 1989;170: 2065-80.
15. Roine RP, Samela KS, Hook-Nikanne J, Kosunen TU, Salaspuro M. Alcohol dehydrogenase mediated acetaldehyde production by Helicobacler pylori - a possible mechanism behind gastric injury. Life Sci 1992; 51:1333-7.
16. Joe A, Murray CS, McBride BC. Nucleotide sequence of a Porphyromonas gingivalis: gene encoding a surface-associated glutamate dehydrogenase and construction of a glutamate dehydrogenase-deficient isogenic mutant. Infect Immun 1994;62:1358-68.
17. Burgess WH, Maciag T. The heparin-binding (fibroblast) growth factor family of proteins. Annu Rev Biochem 1989;58:575-606.
18. Cooper DNW, Barondes SH. Evidence for export of a muscle lectin from cytosol to extracellular matrix and for a novel secretory mechanism. J Cell Biol 1990;110:1681-91.
19. Rubartelli A, Bajetto A, Allavena G, Wollman E, Sitia R. Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway. J Biol Chem 1992;267:24161-4.
20. Kuchler K, Thorner J. Secretion of peptides and proteins lacking hydrophobic signal sequences: the role of adenosine triphosphate-driven membrane translocators. Endocrine Rev 1992;13:499-514.
21. Kessler D, Leibrecht I, Knappe J. Pyruvate-formate-lyase-deactivase and acetyl-CoA reductase activities of Escherichia coli reside on a polymeric protein particle encoded by adhE. FEBS Lett 1991;281:59-63.
22. Goodlove PE, Cunningham PR, Parker J, Clarke DP. Cloning and sequence analysis of the fermentative alcohol-dehydrogenase-encoding gene of Escherichia coli. Gene 1989;85:209-14.
23. Matayoshi S, Oda H, Sarwar G. Relationship between the production of spirosomes and anaerobic glycolysis activity in Escherichia coli B. J Gen Microbiol 1989;135:525-9.
24. +-dependent acetaldehyde/alcohol dehydrogenase from Entamoeba histolytica. Biochem J 1994;303:743-8.