Expression of markers of differentiation in normal bronchial epithelium and bronchial dysplasia

Journal of Pathology

Volumn 178, Issue 2, 1996, Pages 146-150

  Pendleton, Neil ^a,c   Dixon, Glen R ^b   Green, John A ^a   Myskow, Michael W ^b  

^a CLATTERBRIDGE HOSPITAL   (United Kingdom)

^b Broadgreen Hospital   (United Kingdom)

^c MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Bronchial epithelium; Cytokeratins; Dysplasia; Involucrine; Peanut agglutinin

Indexed keywords

CYTOKERATIN; INVOLUCRIN; PEANUT AGGLUTININ;

ARTICLE; BRONCHUS MUCOSA; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; EPITHELIUM DYSPLASIA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRECANCER; PRIORITY JOURNAL;

AGED; AGED, 80 AND OVER; ANTIGENS, DIFFERENTIATION; BIOLOGICAL MARKERS; BRONCHI; CELL DIFFERENTIATION; EPITHELIUM; HUMANS; IMMUNOENZYME TECHNIQUES; KERATINS; LECTINS; LUNG NEOPLASMS; MIDDLE AGED; PEANUT AGGLUTININ; PRECANCEROUS CONDITIONS; PROTEIN PRECURSORS;

EID: 0030040895     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199602)178:2<146::AID-PATH431>3.0.CO;2-N     Document Type: Article

References (26)

1. Auerbach O, Stout AP, Hammond EC, Garfinkel L. Change in bronchial epithelium in relation to cigarette smoking and in relation to lung cancer. N Engl J Med 1961, 265: 253-257
2. Trump BF, McDowell EM, Glavin F, et al. The respiratory epithelium (111). Histogenesis of epidermoid metaplasia and carcinoma in-situ in the human. J Natl Cancer Inst 1978; 61: 587-606.
3. Mason MK, Jordan JW. Outcome of carcinoma in-situ and early invasive carcinoma of the bronchus. Thorax 1982; 37: 453-456.
4. Nuorva K, Soini Y, Kamel D, et al. Concurrent p53 expression in bronchial dysplasias and squamous cell lung cancer. Am J Pathol 1992; 142: 725-732.
5. Sundaresan V, Ganly P, Haselton P. et al. p53 and chromosome 3 abnormalities, characteristic of malignant lung tumours, are detectable in preinvasive lesions of the bronchus. Oncogene 1992, 7: 1989-1997.
6. Pendleton N, Dixon GR, Burnett HE, Occleston ML, Myskow MW, Green JA. Expression of proliferating cell nuclear antigen (PCNA) in dysplasia of the bronchial epithelium. J Pathol 1993; 170: 169-172
7. Fisseler-Eckhoff A, Preberg M, Voss B, Muller KM Extracellular matrix in preneoplastic lesions and early cancer of the lung. Pathol Res Pract 1990, 186: 95-101.
8. Moll R, Franke WW, Schiller DL. The catalog of human cytokeratsins: patterns of expression in normal epithelia, tumours and cultured cells. Cell 1982; 31: 11-24.
9. Banks-Schegel SP, Green H. Involucrin synthesis and tissue assembly by Keratinocytes in natural and cultured human epithelia. J Cell Biol 1980; 90: 732.
10. Watt FM, Keeble S, Fisher C, Hudson DL, Codd J, Salisbury JR. Onset of expression of peanut lectin-binding glycoprotems is correlated with stratification of keratinocytes during human epidermal development in vivo and in vitro J Celt Sci 1989, 94: 355-359.
11. Hsu SM, Raine L, Franger H. Use of avidin-biotm-peroxidase complex (ABC) and unlabelled antibody (PAP) procedures. J Histochem Cyrochem 1981; 29: 577-579.
12. Altman RG (ed.). Some common problems in medical research. In: Practical Statistics in Medical Research London: Chapman and Hall, 1992. 403-409.
13. Altman RG (ed.) Comparing groups - categorical data. In: Practical Statistics in Medical Research. London. Chapman and Hall. 1992, 253-257
14. Sun TT, Eichner R, Schermer A, Cooper D, Nelson WG, Weiss RA Classification, expression and possible mechanisms of evolution of mammalian epithelial keratins; a unifying model In: Levine A, Topp G. Van de Woude D. Watson JD, eds. The Cancer Cell, Vol. 1 Cold Spring Harbor, New York. Cold Spring Harbor Laboratory Press, 1984; 169-176.
15. Moll R. Schiller DL, Franke WW. Cytokeratin 20 in human carcinomas: a new histodiagnostic marker detected by monoclonal antibodies. Am J Pathol 1992. 140: 427-447.
16. Blobel GA, Moll R, Franke WW, Vogt-Moykopf I. Cytokeratins in normal lung and lung carcinomas: adenocarcinomas, squamous cell carcinomas and cultured cell lines. Virchows Arch B [Cell Pathol] 1984; 45: 407-429.
17. Broers JLV, Ramaekers FCS, Rot MK. et al. Cytokeratins in different types of human lung cancer as monitored by chain-specific monoclonal antibodies. Cancer Res 1988; 48: 3221-3229.
18. Elias AD, Cohen BF, Bernai SD. Keratin subtypes of small cell lung cancer. Cancer Res 1988; 48: 2724-2729
19. Wetzels RHW, Schaafsma HE. Leigh IM, et al. Laminin and type VII collagen distribution in different types of lung carcinoma: correlation with expression of keratins 14, 16, 17 and 18. Histopathology 1992; 20: 295-303.
20. 4 J Histochem Cytochem 1991: 39: 7-14.
21. Said JW, Nash G, Sassoon AF, Shintaku P, Banks-Schlegel S. Involucrin in lung tumours. A specific marker for squamous differentiation. Lab Invest 1983: 49: 563-568.
22. Reznik-Schuller H. Sequential morphological alterations in the bronchial epithelium of Syrian Golden hamsters during N-nitrosomorpholine-induced pulmonary tumorigenesis. Am J Pathol 1977; 89: 59-66.
23. Jetten AM, George MA, Smits HL, Volberg TM. Keratin 13 expression is linked to squamous differentiation in the rabbit tracheal epithelial cells and down-regulated by retinoic acid Exp Cell Res 1989; 182: 622-634
24. Rutten AA. Bruyntjes JP, Rameakers FC. Effect of cigarette smoke condcnsate and vitamin A depletion on keratin expression patterns in cultured hamster tracheal epithelium An immunohistomorphological study using monoclonal antibodies to keratins. Virchows Arch B [Cell Pathol] 1988; 56: 111-117.
25. Leube RE, Ruustad TJ. Squamous cell metaplasia in the human lung: molecular characteristics of epithelial stratification Virchows Arch B [Cell Pathol] 1991; 61: 227-253.
26. Purkis PE, Steel JB, MacKenzie IC, Nathrath WBJ, Leigh IM, Lane EB Antibody markers of basal cells in complex epithelia. J Cell Sci 1990: 97: 39-50.