Interaction of lacidipine with its receptor binding site supports a slow onset and long duration of action

Journal of Cardiovascular Pharmacology

Volumn 27, Issue 2, 1996, Pages 290-296

  Graziani, Francesca ^a   Ratti, Emiliangelo ^a   Van Amsterdam, Frank Th M ^a  

^a GSK   (Italy)

Author keywords

Binding characteristics; Guinea pig heart and cerebral tissue; Isradipine; Lacidipine; Long duration of action

Indexed keywords

AMLODIPINE; DILTIAZEM; FLUNARIZINE; ISRADIPINE; LACIDIPINE; NIFEDIPINE; NITRENDIPINE; VERAPAMIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN MEMBRANE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; GUINEA PIG; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; VASCULAR SMOOTH MUSCLE;

ANIMALS; ANTIHYPERTENSIVE AGENTS; BINDING, COMPETITIVE; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CALCIUM CHANNELS, L-TYPE; CEREBRAL CORTEX; DIHYDROPYRIDINES; DRUG ADMINISTRATION SCHEDULE; GUINEA PIGS; ISRADIPINE; MALE; MYOCARDIUM; TIME FACTORS;

EID: 0030040431     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199602000-00017     Document Type: Article

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