Hypergastrinaemia in Cushing's syndrome: Pituitary origin or glucocorticoid-induced?

Clinical Endocrinology

Volumn 44, Issue 3, 1996, Pages 335-339

  Lopez Guzman A ^a,b   Salvador, J ^a   Frutos, R ^a   Diez J J ^a   Iglesias, P ^a   Sastre, J ^a   Gomez Pan A ^a  

^a HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^b HOSPITAL NUESTRA SEÑORA DE SONSOLES   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN; GASTRIN; HYDROCORTISONE;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CUSHING DISEASE; FEMALE; HUMAN; HYPERGASTRINEMIA; MALE; PRIORITY JOURNAL;

EID: 0030039952     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.1996.678499.x     Document Type: Article

References (24)

1. Bardram, L., Lindholm, J. & Rehfeld, J.F. (1987) Gastrin in pituitary tumours. Acta Endocrinologica, 115, 419-422.
2. Bollet, A.J., Black, R. & Bunim, J.J. (1955) Major undesirable side-effects resulting from prednisolone and prednisone. Journal of the American Medical Association, 158, 459-463.
3. Cooke, A.R. & Grossman, M.I. (1966) Effect of hydrocortisone on secretion of acid and pepsin by Heiden hain pouches. Proceedings of the Society for Experimental Biology and Medicine, 123, 459-463.
4. Creutzfeldt, W., Arnold, R., Creutzfeldt, T.C. & Track, N.S. (1975) Pathomorphologic, biochemical and diagnostic aspects of gastrinomas (Zollinger-Ellison syndrome). Human Pathology, 6, 47-76.
5. Doppman, J.L., Nieman, L.K., Cutler G.B. Jr, Chrousos, G.P., Fraker, D.L., Norton, J.A. & Jensen, R.T. (1994) Adrenocorticotropic hormone-secreting islet cell tumors: are they always malignant?. Radiology, 190, 59-64.
6. Dragstedt, L.R., Ragins, H., Dragstedt L.R. II & Evans S.O Jr. (1956) Stress and duodenal ulcer. Annals of Surgery, 144, 450-463.
7. Fonseca, M.E. & Zarate, A. (1987) The significance of elevated levels of gastrin in patients with pituitary adenoma. Clinical Endocrinology, 27, 403-408.
8. Heitz, P.U., Kasper, M., Polak, J.M. & Kloppel, G. (1982) Pancreatic endocrine tumors: immunocytochemical analysis of 125 tumors. Human Pathology, 13, 263-271.
9. Hirschowitz, B.I., Streetem, D.H.P., Pollard, H.M. & Boldt H.I. Jr. (1955) Role of gastric secretions in activation of peptic ulcers by corticotropin (ACTH). Journal of the American Medical Association, 158, 27-32.
10. Larsson, L.I., Grimelius, L., Hakanson, R., Rehfeld, J.F., Stadil, F., Holst, J., Angervall, L. & Sundler, F. (1975) Mixed endocrine pancreatic tumors producing several peptide hormones. American Journal of Pathology, 79, 271-284.
11. Larsson, L.I. & Rehfeld, J.F. (1981) Pituitary gastrins occur in corticotrophs and melanotrophs. Science, 213, 768-770.
12. Long, C.N.H., Katzin, H.B. & Fry, E.G. (1940) The adrenal cortex and carbohydrate metabolism. Endocrinology, 26, 309-344.
13. Maton, P.N., Gardner, J.D. & Jensen, R.T. (1986) Cushing's syndrome in patients with the Zollinger-Ellison syndrome. New England Journal of Medicine, 315, 1-5.
14. McGuigan, J.E. (1974) Role of gastrin in hypersecretory disorders in man. Annual Review of Medicine, 25, 233-249.
15. Meltzer, L.E., Bockman, A.A., Kanenson, W. & Cohen, A. (1958) The incidence of peptic ulcer among patients on long term prednisone therapy. Gastroenterology, 35, 351-356.
16. Messer, J., Reitman, D., Sacks, H.S., Smith, H. & Chalmers, T.C. (1983) Association of adrenocorticosteroid therapy and peptic-ulcer disease. New England Journal of Medicine, 309, 21-24.
17. Oldfield, E.H., Doppman, J.L., Nieman, L.K., Chrousos, G.P., Miller, D.L., Katz, D.A., Cutler G.B. Jr & Loriaux, D.L. (1991) Petrosal sinus sampling with and without corticotropin-releasing hormone for the differential diagnosis of Cushing's syndrome. New England Journal of Medicine, 325, 897-905.
18. Olsen, L., Knigge, U. & Warberg, J. (1992) Gastrin-releasing peptide stimulation of corticotropin secretion in male rats. Endocrinology, 130, 2710-2716.
19. Raptis, S., von Berger, L., Dollinger, H.C., Fazekas, A.T.A. & Pfeiffer, E.F. (1976) Hypergastrinemia induced by glucocorticoid and corticotropin treatment in man. American Journal of Digestive Diseases, 21, 376-380.
20. Rehfeld, J.F. (1978) Localisation of gastrins to neuro- and adenohypophysis. Nature, 271, 771-773.
21. Seino, S., Seino, Y., Matsukura, S., Kurahachi, H., Ikeda, M., Yawata, M., Imura, H. (1978) Effect of glucocorticoids on gastrin secretion in man. Gut, 19, 10-13.
22. Smith, O.K. & Long, C.N.H. (1967) Effect of cortisol on the plasma amino nitrogen of eviscerated adrenalectomized-diabetic rats. Endocrinology, 80, 561-566.
23. Tanaka, K., Itoh, T. & Shimao, S. (1988) Comparison of serum gastrin levels during topical and systemic administration of corticosteroids. Journal of Dermatology, 15, 44-49.
24. Villarreal, R., Ganong, W.F. & Gray, S.J. (1955) Effect of adrenocorticotrophic hormone upon the gastric secretion of hydrochloric acid, pepsin and electrolytes in dog. American Journal of Physiology, 183, 485-494.