Suppression of Cellular Proliferation Using p53 DNA Recognition Site-Related Oligonucleotides

American Journal of the Medical Sciences

Volumn 311, Issue 2, 1996, Pages 65-72

  Ré, Richard N ^a   Cook, Julia L ^a  

^a OCHSNER MEDICAL CENTER   (United States)

Author keywords

Cancer; Oligonucleotides; p53

Indexed keywords

OLIGONUCLEOTIDE; PROTEIN P53;

AMINO ACID SEQUENCE; ARTICLE; CELL PROLIFERATION; CELL TRANSFORMATION; DNA HELIX; DNA REPLICATION; HUMAN; HUMAN CELL; HYDROGEN BOND; LUNG FIBROBLAST; MESANGIUM CELL; MOLECULAR RECOGNITION; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; CELL DIVISION; CELL LINE; CONSENSUS SEQUENCE; DEOXYRIBONUCLEOPROTEINS; DNA, RIBOSOMAL; DNA-BINDING PROTEINS; GENES, P53; HUMANS; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0030039891     PISSN: 00029629     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9629(15)41641-6     Document Type: Article

References (41)

1. Friend SH, Dryja TP, Weinberg RA. Oncogenes and tumor-suppressing genes. N Engl J Med. 1988;318:618-22.
2. Kinzler KW, Nilbert MC, Su L-K, Vogelstein B, Bryan TM, Levy DB, et al. Identification of FAP locus genes from chromosome 5q21. Science. 1991a;253:661-4.
3. Kinzler KW, Nilbert MC, Vogelstein B, Bryan TM, Levy DB, Smith KJ, et al. Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. Science. 1991b;251:1366-70.
4. Nishisho I, Nakamura Y, Miyoshi Y, Miki Y, Ando H, Horii A, et al. Mutation of chromosome 5q21 genes in FAP and colorectal cancer patients. Science. 1991;253:665-9.
5. Nigro JM, Baker SJ, Preisinger AC, Jessup JM, Hostetter R, Cleary K, et al. Mutations in the p53 gene occur in diverse human tumour types. Nature. 1989;342:705-8.
6. Malkin D, Li FP, Strong LC, Fraumeni JF, Nelson CE, Kim DH, et al. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science. 1990;250:1233-8.
7. Vogelstein B, Kinzler KW. p53 Function and dysfunction. Cell. 1992;70:523-6.
8. Kern SE, Pietenpol JA, Thiagalingam S, Seymour A, Kinzler KW, Vogelstein B. Oncogenic forms of p53 inhibit p53-regulated gene expression. Science. 1992;256:827-30.
9. El-Deiry WS, Kern SE, Pietenpol JA, Kinzler KW, Vogelstein B. Definition of a consensus binding site for p53. Nature Genetics. 1992;1:45-9.
10. Funk WD, Pak DT, Karas RH, Wright WE, Shay JW. A transcriptionally active DNA-binding site for human p53 protein complexes. Mol Cell Biol. 1992;12:2866-71.
11. Kern SE, Kinzler KW, Bruskin A, Jarosz D, Friedman P, Prives C, et al. Identification of p53 as a sequence-specific DNA-binding protein. Science. 1991;252:1708-11.
12. Sylvester JE, Petersen R, Schmickel RD. Human ribosomal DNA: Novel sequence organization in a 4.5-kb region upstream from the promotor. Gene. 1989;84:193-6.
13. Sylvester JE, Whiteman DA, Podolsky R, Pozsgay JM, Respess J, Schmickel RD. The human ribosomal RNA gene: Structure and organization of the complete repeating unit. Hum Genet. 1986;73:193-8.
14. Jelinek WR, Toomey TP, Leinwand L, Duncan CH, Biro PA, Choudary PV, et al. Ubiquitous, interspersed repeated sequences in mammalian genomes. Proc Natl Acad Sci U S A. 1980;77:1398-1402.
15. Moser HE, Dervan PB. Sequence-specific cleavage of double helical DNA by triple helix formation. Science. 1987;238:645-50.
16. Strobel SA, Moser PB, Dervan PB. Double-strand cleavage of genomic DNA at a single site by triple-helix formation. Journal of the American Chemical Society. 1988;110:7927-9.
17. Blume SW, Gee JE, Shrestha K, Miller DM. Triple helix formation by purine-rich oligonucleotides targeted to the human dihydrofolate reductase promoter. Nucleic Acids Res. 1992;20: 1777-84.
18. Cooney M, Czernuszewicz G, Postel EH, Flint SJ, Hogan ME. Site-specific oligonucleotide binding represses transcription of the human c-myc gene in vitro. Science. 1988;241:456-9.
19. Orson FM, Thomas DW, McShan WM, Kessler DJ, Hogan ME. Oligonucleotide inhibition of IL2Rα mRNA transcription by promoter region collinear triplex formation in lymphocytes. Nucleic Acids Res. 1991;19:3435-41.
20. Postel EH, Flint SJ, Kessler DJ, Hogan ME. Evidence that a triplex-forming oligodeoxyribonucleotide binds to the c-myc promoter in Hela cells, thereby reducing c-myc mRNA levels. Proc Natl Acad Sci U S A. 1991;88:8227-31.
21. Favre D. Improved phenol-based method for the isolation of DNA fragments from low melting temperature agarose gels. BioTechniques. 1992;13:24-6.
22. Bakris GL, Fairbanks R, Traish AM. Arginine vasopressin stimulates human mesangial cell production of endothelin. J Clin Invest. 1991;87:1158-64.
23. Oren M, Maltzman W, Levine AJ. Post-translational regulation of the 54K cellular tumor antigen in normal and transformed cells. Mol Cell Biol. 1981;1:101-10.
24. Reich NC, Oren M, Levine AJ. Two distinct mechanisms regulate the levels of a cellular tumor antigen, p53. Mol Cell Biol. 1983;3:2143-50.
25. Lane DP, Benchimol S. p53: Oncogene or anti-oncogene? Genes Dev. 1990;4:1-8.
26. Levine AJ. The p53 tumour suppressor gene and product. Cancer Surveys. 1992;12:59-79.
27. Milner J, Medcalf EA. Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation. Cell. 1991;65:765-74.
28. Callahan DE, Trapane TL, Miller PS, Ts'o POP, Kan L-S. Comparative circular dichroism and fluorescence studies of oligodeoxyribonucleotide and oligodeoxyribonucleoside methylphosphonate pyrimidine strands in duplex and triplex formation. Biochemistry. 1991;30:1650-5.
29. Kool ET. Molecular recognition by circular oligonucleotides: Increasing the selectivity of DNA binding. Journal of the American Chemical Society. 1991;113:6265-6.
30. Maher LJ, Wold B, Dervan PB. Inhibition of DNA binding proteins by oligonucleotide-directed triple helix formation. Science. 1989;245:725-30.
31. Rakowicz-Szulczynska EM, Koprowski H. Antagonistic effect of PDGF and NGF on transcription of ribosomal DNA and tumor cell proliferation. Biochem Biophys Res Commun. 1989;163:649-56.
32. DeLong EF, Wickham GS, Pace NR. Phylogenetic stains: Ribosomal RNA-based probes for identification of single cells. Science. 1989;243:1360-3.
33. Bremer H, Dennis PP. In: Neinhardt FC, ed. Escherichia coli and Salmonella typhimurium. Cellular and Molecular Biology. Washington: American Society of Microbiology; 1987: 1527-42.
34. Emerson CP. Regulation of the synthesis and the stability of ribosomal RNA during contact inhibition of growth. Nature New Biology. 1971;232:101-6.
35. 9 myoblast differentiation. J Mol Biol. 1979;134:727-41.
36. Fontoura BMA, Sorokina EA, David E, Carroll RB. p53 is covalently linked to 5.8S rRNA. Mol Cell Biol. 1992;12:5145-51.
37. Beattie KL, Wiegand RC, Radding CM. Uptake of homologous single-stranded fragments by superhelical DNA. J Mol Biol. 1977;116:783-803.
38. Ginsberg D, Mechta F, Yaniv M, Oren M. Wild-type p53 can down-modulate the activity of various promoters. Proc Natl Acad Sci U S A. 1991;88:9979-83.
39. Santhanam U, Ray A, Sehgal PB. Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product. Proc Natl Acad Sci U S A. 1991;88:7605-9.
40. Chin K-V, Ueda K, Pastan I, Gottesman MM. Modulation of activity of the promoter of the human MDR1 gene by ras and p53. Science. 1992;255:459-62.
41. Farmer G, Bargonetti J, Zhu H, Friedman P, Prywes R, Prives C. Wild-type p53 activates transcription in vitro. Nature. 1992;358:83-6.