Nitroimidazole-based 'extruded mustards' designed as reductively activated hypoxia-selective cytotoxins

Anti-Cancer Drug Design

Volumn 11, Issue 5, 1996, Pages 383-402

  Hay, Michael P ^a   Denny, William A ^a   Wilson, William R ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Bioreductive drugs; Cyclization; Hypoxia selective; Nitrogen mustard; Nitroimidazoles

Indexed keywords

1 (2 BROMOETHYLAMINO) 3 (2 NITRO 1 IMIDAZOLYL) 2 PROPANOL; MUSTARD GAS DERIVATIVE; NITROIMIDAZOLE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYCLIZATION; CYTOTOXICITY; DRUG STABILITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYPOXIC CELL; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; CRICETULUS; DRUG DESIGN; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MECHLORETHAMINE; NITROGEN MUSTARD COMPOUNDS; NITROIMIDAZOLES; PRODRUGS; STRUCTURE-ACTIVITY RELATIONSHIP;

BRASSICACEAE; STAPHYLOCOCCUS PHAGE 3A;

EID: 0030038630     PISSN: 02669536     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

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