Human cancers detected by proton MRS and chemical shift imaging ex vivo

Anticancer Research

Volumn 16, Issue 3 B, 1996, Pages 1521-1531

  Mountford, Carolyn E ^a   Mackinnon, Wanda B ^a   Russell, Peter ^a   Rutter, Allison ^a   Delikatny, Edward J ^a  

^a NONE

Author keywords

Cancer; Chemical shift imaging; Histopathology; Lipid; Magnetic resonance spectroscopy

Indexed keywords

LIPID;

BIOCHEMISTRY; CANCER; CANCER GRADING; CELL TRANSFORMATION; COLON CANCER; CONFERENCE PAPER; HUMAN; HUMAN TISSUE; IMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; THYROID CANCER; TUMOR BIOPSY; UTERUS CANCER;

COLONIC NEOPLASMS; FEMALE; HUMANS; LIPID METABOLISM; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; NEOPLASMS; THYROID NEOPLASMS; UTERINE CERVICAL NEOPLASMS;

EID: 0030037189     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (38)

1. Mountford CE, Lean CL, Mackinnon WB and Russell P: The use of proton MR in cancer pathology. In: Annual reports on NMR spectroscopy (Webb GA. Ed). Academic Press, 1993, Vol.27, pp.173-215.
2. Fearon ER and Vogelstein B: A genetic model for colorectal tumorigenesis. Cell 61: 759-767, 1990.
3. Fagin JA, Matsuo K, Karmakar A, Chcn DL, Tang S and Koeffler HP: High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas. J Clin Invest 91: 179-184, 1993.
4. Cross KJ, Holmes KJ, Mountford CE and Wright PE: Assignment of acyl chain resonances from membranes of mammalian cells by two-dimensional NMR methods. Biochemistry 23: 5895-5897, 1984.
5. May GL, Wright LC, Dyne M, Mackinnon WB, Fox RM and Mountford CE: Plasma membrane lipid composition of vinblastine sensitive and resistant human leukaemic lymphoblasts. Int J Cancer 42: 728-733, 1988.
6. Schroeder F, Goetz I and Roberts E: Age-related alterations in cultured human fibroblast membrane structure and function. Mechanisms of Ageing and Development 25: 365-389, 1984.
7. Mackinnon WB, May GL and Mountford CE: Esterified cholesterol and triglyceride are present in plasma membranes of Chinese hamster ovary cells. Eur J Biochem 205: 827-839, 1992.
8. Mountford CE, Mackinnon WB, Bloom M, Burnell EE and Smith ICP: NMR methods for characterising the state of the surfaces of complex mammalian cells. J Biochem Biophys Methods 9: 323-330, 1984.
9. Mackinnon WB, Dyne M, Holmes KT, Mountford CE, Gupta RS: Further evidence that the narrow 'H magnetic resonance signals from malignant cells do not arise from intracellular lipid droplets. NMR in Biomedicine 2: 161-164, 1989.
10. Mountford CE and Wright LC: Organisation of lipids in the plasma membranes of malignant and stimulated cells: a new model. TIBS 13: 172-177, 1988.
11. Freitas I, Pontiggia P, Barni S,Bertone V, Parente M, Novarina A, Roveta G, Gerzeli G and Stoward P: Histochemical probes for the detection of hypoxic tumour cells. Anticancer Res 10: 613-622, 1990.
12. Hirakawa T, Maruyama K, Kohl NE, Kodama T and Ruley HE: Massive accumulation of neutral lipids in cells conditionally transformed by an activated H-ras oncogene. Oncogene 6: 289-295, 1991.
13. Brown TR: Practical applications of chemical shift imaging. NMR in Biomed 5: 238-243, 1992.
14. Delikatny EJ, Russell P, Hunter JC, Hancock R, Atkinson K, van-Haaften-Day C and Mountford CE: Proton MR and human cervical neoplasia. I. Ex vivo spectroscopy allows distinction of invasive carcinoma of the cervix from carcinoma in situ and other preinvasive lesions Radiology 188: 791-796, 1993.
15. Kunnecke B, Delikatny EJ, Russell P. Hunter JC and Mountford CE: Proton magnetic resonance and human cervical neoplasia II: Ex vivo chemical shift microimaging. J Magn Res 104B: 135-142, 1994.
16. Li Volsi VA: Follicular lesions of the thyroid. In: Surgical Pathology of the Thyroid (Saunders WB, ed). Philadelphia, 1990, Chapter 9, pp. 173-212.
17. Mazzaferri EL: Management of a solitary thyroid nodule. New Engl J Med 328: 553-559, 1993.
18. Mazzaferri EL: Thyroid cancer in thyroid nodules: finding a needle in the haystack. Am J Med 93: 359-362, 1992.
19. Russell P, Lean CL, Delbridge L, May GL, Dowd S and Mountford CE: Proton magnetic resonance and human thyroid neoplasia. I. Discrimination between benign and malignant neoplasms. Am J Med 96: 383-388, 1994.
20. Mackinnon WB, Delbridge L, Russell P, Lean CL, May GL, Doran S. Dowd S and Mountford CE:Two-dimensional proton magnetic resonance spectroscopy provides tissue characterisation of thyroidneoplasms. World J Surgery, submitted, 1995.
21. Gefter WB, Spritzer CE, Eisenberg B, LiVolsi VA, Axel L, Velchik M, Alavi A, Schenck J and Kressel HY: Thyroid imaging with high-field-strength surface coil MR. Radiology 164: 483-490, 1987.
22. Noma S, Kanaoka M, Minami S, Sagoh T, Yamashita K, Nishimura K, Togashi K, Itoh K, Fujisawa I, Nakano Y, Oomura M, Tasaka Y, Itoh H and Konshni J: Thyroid masses: MR imaging and pathologic correlation. Radiology 168: 759-764, 1988.
23. Charkes ND, Maurer AH. Siegel JA, Radecki PD and Malmud LS: MR imaging in thyroid disorders: correlation of signal intensity with Graves disease activity. Radiology 164: 491-494, 1987.
24. Rutter A, Kunnecke B, Russell P, Delbridge L and Mountford CE: Proton magnetic resonance and human thyroid neoplasia. III. Ex vivo chemical shift imaging. J Magn Res, in press, 1995.
25. Bokey EL, Chapuis PH, Hughes WJ, Koorey SG, Hinder JM, Edwards R: Morbidity, mortality and survival following resection for carcinoma of the rectum at Concord Hospital. Aust NZJ Surg 60: 253-259, 1990.
26. Chapuis PH, Newland RC, Dent OF: Staging in colon cancer. Seminars in Colon and Rectal Surgery 2: 9-16, 1991.
27. Lean C, Mackinnon WB, Delikatny EJ, Whitehead RH and Mountford CE: Cell surface fucosylation and magnetic resonance spectroscopy characterization of human malignant colorectal cells. Biochemistry 31: 11095-11105, 1992.
28. Mackinnon WB, Huschtscha L, Dent K, Hancock R, Paraskeva C and Mountford CE: Correlation of cellular differentiation in human colorectal carcinoma and adenoma cell lines with metabolite profiles determined by 'H magnetic resonance spectroscopy. Int J Cancer 59: 248-261, 1994.
29. Smith ICP. Princz EJ and Saunders JK: Magnetic resonance spectroscopy in cancer research. J Can Assoc Radiol 41: 32-38, 1990.
30. 1H MRS: correlation with histopalhology. Mag Reson Med 30: 525-533, 1993.
31. Ende D, Rutter A, Russell P and Mountford CE: Chemical shift imaging of human colorectal tissue (ex vivo). NMR in Biomed, in press, 1995.
32. 1H NMR spectroscopy of colon tumors and normal mucosal biopsies: elevated taurine levels and reduced polyethyleneglycol absorption in tumors may have diagnostic significance. NMR in Biomed 6: 111-118, 1993.
33. 1H MR visible lipids in colon tissue from normal and carcinogen-treated rats. NMR in Biomed 8: 33-40, 1995.
34. Hirai T, Nimura Y and Sakai H: The three-dimensional microstructure of intramural lymphatics in the canine large intestine. Gastroenterol Japonica 25: 169-174, 1990.
35. Robbins SL and Cotran RS: In: Pathologic basis of discase (Igaku-Shoin and Saunders, Eds). 2nd Edition. 1984, Chapter 26, p.976.
36. Kuesel A, Sutherland GR, Halliday W and Smith ICP: 1H MRS of high grade astrocytomas: mobile lipid accumulation in necrotic tissue. NMR in Biomed 7: 149-155, 1994.
37. 1H NMR spectra of a myeloma cell line correlates with the induced formation of cytoplasmic lipid droplets. Magn Reson Med 29: 546-550, 1993.
38. May GL, Wright LC, Holmes KT, Williams PG, Smith ICP, Wright PE, Fox RM and Mountford CE: Assignment of methylene proton resonances in NMR spectra of embryonic and transformed cells to plasma membrane triglyceride. J Biol Chem 261: 3048-3053, 1986.