The Salmonella virulence plasmid enhances Salmonella-induced lysis of macrophages and influences inflammatory responses

Infection and Immunity

Volumn 64, Issue 8, 1996, Pages 3385-3393

  Guilloteau, Laurence A ^a,d   Wallis, Timothy S ^b   Gautier, Anne V ^a,b   MacIntyre, Sheila ^a   Platt, David J ^c   Lax, Alistair J ^b  

^a UNIVERSITY OF READING   (United Kingdom)

^b INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

^c GLASGOW ROYAL INFIRMARY   (United Kingdom)

^d CEMAGREF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; BACTERIAL INFECTION; BACTERIAL VIRULENCE; CYTOLYSIS; FEMALE; INFLAMMATION; INTRACELLULAR KILLING; MACROPHAGE FUNCTION; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PLASMID; PRIORITY JOURNAL; SALMONELLA DUBLIN; SALMONELLA TYPHIMURIUM; SURVIVAL;

EID: 0030036899     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.8.3385-3393.1996     Document Type: Article

References (41)

1. Abshire, K. Z., and F. C. Neidhardt. 1993. Growth rate paradox of Salmonella typhimurium within host macrophages. J. Bacteriol. 175:3744-3748.
2. Austyn, J. M., and S. Gardon. 1981. F4/80, a monoclonal antibody directed specifically against the mouse macrophage. Eur. J. Immunol. 11:805-815.
3. Baird, G. D., E. J. Manning, and P. W. Jones. 1985. Evidence for related virulence sequences in plasmids of Salmonella dublin and Salmonella typhimurium. J. Gen. Microbiol. 131:1815-1823.
4. Benninger, P. R., G. Chikami, K. Tanabe, C. Roudier, J. Fierer, and D. G. Guiney. 1988. Physical and genetic-mapping of the Salmonella dublin virulence plasmid pSDL2 - relationship to plasmids from other Salmonella strains. J. Clin. Invest. 81:1341-1347.
5. Brown, D. J, J. E. Olsen, and D.J. Platt. 1992. The effect of the introduction of Salmonella typhimurium virulence genes into other serotypes of Salmonella enterica, p. 123-129. In Salmonella and salmonellosis. Proceedings of the World Veterinary Poultry Association, CNEVA/INRA, Ploufragan/Saint Brieuc, France.
6. Buchmeier, N. A., and F. Heffron. 1989. Intracellular survival of wild-type Salmonella typhimurium and macrophage-sensitive mutants in diverse populations of macrophages. Infect. Immun. 57:1-7.
7. Danbara, H., R. Moriguchi, S. Suzuki, Y. Tamura, M. Kijima, K. Oishi, H. Matsui, A. Abe, and M. Nakamura. 1992. Effect of 50 kilobase plasmid, pKDSC50, of Salmonella choleraesuis RF-1 strain on pig septicemia. J. Vet. Med. Science. 54:1175-1178.
8. Dunlap, N. E., W. H. Benjamin, Jr., R. D. McCall, Jr., A. B. Tilden, and D. E. Briles. 1991. A "safe site" for Salmonella typhimurium is within splenic cells during the early phase of infection in mice. Microb. Pathog. 10:297-310.
9. Emoto, M., H. Danbara, and Y. Yoshikai. 1992. Induction of γ/δ cells in murine salmonellosis by an avirulent but not by a virulent strain of Salmonella choleraesuis. J. Exp. Med. 176:363-372.
10. Ermel, G., J. Protais, and P. Colin. 1995. Survie intracellulaire de souches de salmonelles dans les macrophages péritonéaux de poulet, abstr. JE-33. In report of the Fourth National Congress of the Société Française de Microbiologie, Tours, France.
11. Fields, P. I., R. V. Swanson, C. G. Haidaris, and F. Heffron. 1986. Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent. Proc. Natl. Acad. Sci. USA 83:5189-5193.
12. Fierer, J., L. Eckmann, F. Fang, C. Pfeifer, B. B. Finlay, and D. Guiney. 1993. Expression of the Salmonella virulence plasmid gene spvB in cultured macrophages and nonphagocytic cells. Infect. Immun. 61:5231-5236.
13. Gordon, S., I. Fraser, D. Nath, D. Hughes, and S. Clarke. 1992. Macrophages in tissues and in vitro. Curr. Opin. Immunol. 4:25-32.
14. Guilloteau, L. A., A. J. Lax, S. Maclntyre, and T. S. Wallis. 1996. The Salmonella dublin virulence plasmid does not modulate early T-cell responses in mice. Infect. Immun. 64:222-229.
15. Gulig, P. A., and R. Curtiss III. 1987. Plasmid-associated virulence of Salmonella typhimurium. Infect. Immun. 55:2891-2901.
16. Gulig, P. A., H. Danbara, D. G. Guiney, A. J. Lax, F. Norel, and M. Rhen. 1993. Molecular analysis of spv virulence genes of the salmonella virulence plasmids. Mol. Microbiol. 7:825-830.
17. Gulig, P. A., and T. J. Doyle. 1993. The Salmonella typhimurium virulence plasmid increases the growth rate of salmonellae in mice. Infect. Immun. 61:504-511.
18. Heffernan, E. J., J. Fierer, G. Chikami, and D. Guiney. 1987 Natural history of oral Salmonella dublin infection in BALB/c mice: effect of an 80-kilobase-pair plasmid on virulence. J. Infect. Dis. 155:1254-1259.
19. Helmuth, R., R. Stephan, C. Bunge, B. Houg, A. Steinbeck, and E. Bulling. 1985. Epidemiology of virulence-associated plasmids and outer membrane protein patterns within seven common Salmonella scrotypes. Infect. Immun. 48:175-182.
20. Hirsch, S., and S. Gordon. 1983. Polymorphic expression of a neutrophil differentiation antigen revealed by monoclonal antibody 7/4. Immunogenetics 18:229-239.
21. Hoertt, B. E., J. Ou, D. J. Kopecko, L. S. Baron, and R. L. Warren. 1989. Novel virulence properties of the Salmonella typhimurium virulence-associated plasmid: immune suppression and stimulation of splenomegaly. Plasmid 21:48-58.
22. Hsu, H. S. 1989. Pathogenesis and immunity in murine salmonellosis. Microbiol. Rev. 53:390-409.
23. Kawahara, K., T. Hamaoka, S. Suzuki, M. Nakamura, S. Y. Murayama, T. Arai, N. Terakado, and H. Danbara. 1989. Lipopolysaccharide alteration mediated by the virulence plasmid of Salmonella. Microb. Pathog. 7:195-202.
24. Lax, A. J., P. A. Barrow, P. W. Jones, and T. S. Wallis. 1995. Current perspectives in salmonellosis. Br. Vet. J. 151:351-377.
25. Manning, E. J., G. D. Baird, and P. W. Jones. 1986. The role of plasmid genes in the pathogenicity of Salmonella dublin. J. Med. Microbiol. 21:239-243.
26. Pardon, P., M. Y. Popoff, C. Coynault, J. Marly, and I. Miras. 1986. Virulence-associated plasmids of Salmonella serotype typhimurium in experimental murine infection. Ann. Inst. Pasteur. Microbiol. 137:47-60.
27. Platt, D. J., J. Taggart, and K. A. Heraghty. 1988. Molecular divergence of the serotype specific plasmid (pSLT) among strains of Salmonella typhimurium of human and veterinary origin and comparison of pSLT with the serotype specific plasmids of 5. enteritidis and S. dublin. J. Med. Microbiol. 27:277-284.
28. Rhen, M., P. Riikonen, and S. Taira. 1993. Transcriptional regulation of Salmonella enterica virulence plasmid genes in cultured macrophages. Mol. Microbiol. 10:45-56.
29. Riikonen, P., P. H. Mäkelä, H. Saarilahti, and S. Sukupolvi. 1992. The virulence plasmid does not contribute to growth of Salmonella in cultured murine macrophages. Microb. Pathog. 13:281-291.
30. Rosen, H., and S. Gordon. 1990. The role of the type 3 complement receptor in the induced recruitment of myelomonocytic cells to inflammatory sites in the mouse. Am. J. Respir. Cell Mol. Biol. 3:3-10.
31. Springer, T., G. Galfré, D. S. Secher, and C. Milstein. 1979. Mac-1: a macrophage differentiation antigen identified by monoclonal antibody. Eur. J. Immunol. 9:301-306.
32. Sukupolvi, S., P. Riikonen, S. Taira, H. Saarilahti, and M. Rhen. 1992. Plasmid-mediated serum resistance in Salmonella enterica. Microb. Pathog. 12:219-225.
33. Vandenbosch, J. L., D. R. Kurlandsky, R. Urdangaray, and G. W. Jones. 1989. Evidence of coordinate regulation of virulence in Salmonella typhimurium involving the rsk clement of the 95-kilobase plasmid. Infect. Immun. 57:2566-2568.
34. Van Dissel, J. T., J. J. M. Stikkelbroeck, B. C. Michel, P. C. J. Leijh, and R. Van Forth. 1987. Salmonella typhimurium-specific difference in rate of intracellular killing by resident peritoneal macrophages from Salmonella-resistant CBA and Salmonella-susceptible C57BL/10 mice. J. Immunol. 138:4428-4434.
35. Van Leengoed, L. A., E. M. Kamp, and J. M. A. Pol. 1989. Toxicity of Haemophilus pleuropneumoniae to porcine lung macrophages. Vet. Microb. 19:337-349.
36. Wallis, T. S., S. Paulin, and P. W. Jones. Submitted for publication.
37. Wallis, T. S., S. Paulin, J. Plested, P. R. Watson, and P. W. Jones. 1995 The Salmonella dublin virulence plasmid mediates systemic but not enteric phases of salmonellosis in cattle. Infect. Immun. 63:2755-2761.
38. Williamson, C. M., G. D. Baird, and E. J. Manning. 1988. A common virulence region on plasmids from eleven serotypes of Salmonella. J. Gen. Microbiol. 134:975-982.
39. Williamson, C. M., G. D. Pullinger, and A. J. Lax. 1988. Identification of an essential virulence region on Salmonella plasmids. Microb. Pathog. 5:469-473.
40. Yahara, I., F. Harada, S. Sekita, K. Yoshihira, and S. Natori. 1982. Correlation between effects of 24 different cytochalasins on cellular structures and cellular events and those on actin in vitro. J. Cell Biol. 92:69-78.
41. Zychlinsky, A., C. Fitting, J. M. Cavaillon, and P. J. Sansonetti. 1994. Interleukin 1 is released by murine macrophages during apoptosis induced by Shigella flexneri. J. Clin. Invest. 94:1328-1332.