Relationship of in vitro data on drug metabolism to in vivo pharmacokinetics and drug interactions: Implications for diazepam disposition in humans

Journal of Clinical Psychopharmacology

Volumn 16, Issue 4, 1996, Pages 267-272

  Schmider, J ^a   Greenblatt, D J ^a   Von Moltke, L L ^a   Shader, R I ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; DIAZEPAM; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SEROTONIN UPTAKE INHIBITOR;

COMPETITIVE INHIBITION; DEMETHYLATION; DRUG DISPOSITION; DRUG INHIBITION; DRUG METABOLISM; EDITORIAL; LIVER MICROSOME; MAMMAL CELL; PRIORITY JOURNAL;

ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 ENZYME SYSTEM; DIAZEPAM; HUMANS; ISOENZYMES; LIVER; METABOLIC CLEARANCE RATE; MIXED FUNCTION OXYGENASES;

EID: 0030036673     PISSN: 02710749     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004714-199608000-00001     Document Type: Editorial

References (0)