Rat pineal α1-adrenoceptor subtypes: Studies using radioligand binding and reverse transcription-polymerase chain reaction analysis

British Journal of Pharmacology

Volumn 118, Issue 5, 1996, Pages 1246-1252

  Sugden, David ^a   Anwar, Naveed ^a   Klein, David C ^a,b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

mRNA expression; Pineal; Reverse transcription polymerase chain reaction (RT PCR); 1 adrenoceptor subtypes

Indexed keywords

2 [[2 (2,6 DIMETHOXYPHENOXY)ETHYL]AMINOMETHYL] 1,4 BENZODIOXAN; 3,4,4A,5,10,10A HEXAHYDRO 6 METHOXY 4 METHYL 9 METHYLTHIO 2H NAPHTH[2,3 B][1,4]OXAZINE; 5 METHYLURAPIDIL; ADRENERGIC RECEPTOR STIMULATING AGENT; ALKYLATING AGENT; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 1B ADRENERGIC RECEPTOR; ALPHA 1D ADRENERGIC RECEPTOR; BENOXATHIAN; CHLOROETHYLCLONIDINE; COMPLEMENTARY DNA; IODINE 125; MESSENGER RNA; OXYMETAZOLINE; PHENTOLAMINE; RECEPTOR SUBTYPE;

ANIMAL CELL; ARTICLE; BINDING SITE; COMPETITIVE INHIBITION; ENANTIOMER; NONHUMAN; PINEAL BODY; PINEALOCYTE; PRIORITY JOURNAL; RADIOASSAY; RAT; RECEPTOR AFFINITY; RECEPTOR BINDING; RECEPTOR GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0030036626     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15530.x     Document Type: Article

References (44)

1. 1-adrenoceptors. Eur. J. Pharmacol. (Mol. Pharm. Sec.) 172, 131-145.
2. BUDA, M. & KLEIN, D.C. (1978). A suspension culture of pinealocytes: Regulation of N-acetyltransferase activity. Endocrinology, 103, 1483-1493.
3. BYLUND, D.B., EIKENBERG, D.C., HIEBLE, J.P., LANGER, S.Z., LEFKOWITZ, R.J., MINNEMAN, K.P., MOLINOFF, P.B., RUFFOLO, R.R. & TRENDELENBERG, U. (1994). IV. International Union of Pharmacology nomenclature of adrenoceptors. Pharmacol. Rev., 46, 121-136.
4. 50) of an enzymatic reaction. Biochem. Pharmacol., 33, 3099-3108.
5. CHOMCZYNSKI, P & SACCHI, N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 161, 156-159.
6. 1-adrenergic receptor. Proc. Natl. Acad. Sci. U.S.A., 85, 7159-7163.
7. DELEAN, A.P., MUNSON, P.J. & RODBARD, D. (1978). Simultaneous analysis of families of sigmoidal curves: Application to bioassay, radioligand assay and physiological dose-response curves. Am. J. Physiol., 235, E97-E102.
8. DEVEREUX, J., HAEBERLI, P. & SMITHIES, A. (1984). A comprehensive set of sequence analysis programs for VAX and CONVEX systems. Nucleic Acids Res., 12, 387-395.
9. 1-Adrenoceptor classification: sharpening Occam's razor. Trends Pharmacol. Sci., 15, 167-170.
10. 1-Adrenergic action: receptor subtypes, signal transduction and regulation. Cell. Signalling. 5, 539-547.
11. 1-adrenergic receptors revealed by chlorethylclonidine. Mol. Pharmacol., 32, 505-510.
12. 1adrenergic stimulation of pineal phosphatidylinositol phosphodiesterase (phospholipase C) activity. J. Pineal Res., 5, 553-564.
13. KLEIN, D.C., SUGDEN, D. & WELLER, J.L. (1983). Postsynaptic α-adrenergic receptors potentiate the β-adrenergic stimulation of serotonin N-acetyltransferase. Proc. Natl. Acad. Sci. U.S.A., 80, 599-603.
14. 1-adrenergic receptor subtypes: MDCK-D1 cells, but not rat cortical membranes, posses a single population of receptors. Mol. Pharmacol., 39, 407-413.
15. KUWANO, R., IWANAGA, T., NAKAJIMA, T., MASUDA, T. & TAKAHASHI, Y. (1983). Immunocytochemical demonstration of hydroxyindole-O-methyltransferase (HIOMT), neuron specific enolase and S-100 protein in the bovine pineal gland. Brain Res., 274, 171-175.
16. 1A-subtype. Mol. Pharmacol., 46, 414-422.
17. LEATHERBARROW, R.J. (1987). ENZFITTER - A Non-Linear Regression Data Analysis Program for the IBM PC. Amsterdam: Elsevier-Biosoft.
18. 1A-adrenergic receptor. J. Biol. Chem., 266, 6365-6369.
19. 1-Adrenergic receptor subtype, inositol phosphates and sources of cell calcium. Pharmacol. Rev., 40, 87 119.
20. 1-Adrencrgic receptor subtypes. Ann. Rev. Pharmacol. Toxicol., 34, 117-133.
21. MINNEMAN, K.P., HAN, C. & ABEL, P.W. (1988). Comparison of α1-adrenergic receptor subtypes distinguished by chlorethylclonidine and WB4101. Mol. Pharmacol., 33, 509-514.
22. 1-adrenergic receptor subtypes. Mol. Pharmacol., 46, 929-936.
23. 1A subtype. Mol. Pharmacol., 46, 823-831.
24. 1-agonist, on canine cataplexy, a disorder of rapid eye movement sleep. Ear. J. Pharmacol., 205, 11-16.
25. 1-adrenoceptor-mediated second messenger responses in rat cerebral cortex slices. Br. J. Pharmacol., 100, 3-4.
26. RUFFOLO, R.R., NICHOLS, A.J., STADFL, J.M. & HFIBLE, J.P. (1991). Structure and function of α-adrenoceptors. Pharmacol. Rev., 43, 475-505.
27. 2+]i analysis and biochemical characterization of pinealocytes immobilized with novel attachment peptide preparation. Brain Res., 614, 251-256.
28. 1-adrenoceptor subtypes: selective antagonists suggest the existence of a fourth subtype. Eur. J. Pharmacol., 227, 433-436.
29. 1-adrenergic receptor subtype. J. Biol. Chem., 265, 8183-8189.
30. SMITH, T.L., EICHBERG, J. & HAUSER, G. (1979). Postsynaptic localization of the alpha receptor-mediated stimulation of phosphatidylinositol turnover in pineal gland. Life Sci., 24, 2179-2184.
31. 1C-adrenergic receptor from cardiac myocytes. Circ. Res., 75, 796-802.
32. SUGDEN, D. (1989). Melatonin biosynthesis in the mammalian pineal gland. Experientia, 45, 922-932.
33. 1adrenergic receptor blockade. Pharm. Sci., 1, 31-33.
34. 1-adrenoceptor subtype in the rat pineal gland. Br. J. Pharmacol., 116, 206P.
35. 125I-HEAT). Endocrinology, 114, 435-440.
36. 1-adrenoceptor. Brain Res., 325, 345-348.
37. 1-adrenoceptors. J. Neurochem., 44, 63-67.
38. SUGDEN, A.L., SUGDEN, D. & KLEIN, D.C. (1986). Essential role of calcium influx in the adrenergic regulation of cAMP and cGMP in rat pincalocytes. J. Biol. Chem., 261, 11608-11612.
39. 1-Adrenergic agonists elevate cytosolic calcium in rat pinealocytes by increasing net influx. J. Biol. Chem., 262, 741-746.
40. SUGDEN, D., VANECEK, J., KLEIN, D.C., THOMAS, T.P. & ANDERSON, W.B. (1985). Activation of protein kinase C potentiates isoprenaline-induced cyclic AMP accumulation in rat pinealocytes. Nature, 314, 359-361.
41. 1- and β-adrenergic regulation of adenosine 3′, 5′-monophosphate and guanosine 3′.5′-monophosphate in rat pinealocytes. Endocrinology, 116, 2167-2173.
42. VOIGT, M.M., KISPERT, J. & CHIN, H. (1990). Sequence of a rat brain cDNA encoding an alpha-1B adrenergic receptor. Nucl. Acids Res., 18, 1053.
43. WICHT, H., KORF, H.-W. & SCHAAD, N.C. (1993). Morphological and immunocytochemical heterogeneity of cultured pinealocytes from one-week and two-month old rats: Planimetrie and densitometric investigations. J. Pineal Res., 14, 128-137.
44. 1b-adrenergic receptors. J. Biol. Chem., 265, 17601-17606.