메뉴 건너뛰기




Volumn 7, Issue 5, 1996, Pages 441-444

Clinical studies with angiogenesis inhibitors: Biological rationale and challenges for their evaluation

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; TECOGALAN;

EID: 0030036156     PISSN: 09237534     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.annonc.a010631     Document Type: Editorial
Times cited : (25)

References (45)
  • 1
    • 3042972715 scopus 로고    scopus 로고
    • The accumulation of multiple genetic abnormalities in individual tumor cells in human breast cancers: Clinical prognostic implications
    • Shackney S.E. Pollice A.A. Smith C.A. The accumulation of multiple genetic abnormalities in individual tumor cells in human breast cancers: Clinical prognostic implications Cancer J Sci Am 2 1996 106 113
    • (1996) Cancer J Sci Am , vol.2 , pp. 106-113
    • Shackney, S.E.1    Pollice, A.A.2    Smith, C.A.3
  • 2
    • 0028915223 scopus 로고
    • Genetic instability occurs in the majority of young patients with colorectal cancer
    • Liu B. Farrington S.M. Petersen G.M. Genetic instability occurs in the majority of young patients with colorectal cancer Nature Med 1 1995 348 352
    • (1995) Nature Med , vol.1 , pp. 348-352
    • Liu, B.1    Farrington, S.M.2    Petersen, G.M.3
  • 3
    • 0024592699 scopus 로고
    • Tumor cell societies
    • Heppner G.H. Tumor cell societies J Natl Cancer Inst 81 1989 648 649
    • (1989) J Natl Cancer Inst , vol.81 , pp. 648-649
    • Heppner, G.H.1
  • 4
    • 0022356861 scopus 로고
    • Tumor cell heterogeneity: Implications for clinical practice
    • Schilsky R.L. Tumor cell heterogeneity: Implications for clinical practice Semin Oncol 12 1985 203 206
    • (1985) Semin Oncol , vol.12 , pp. 203-206
    • Schilsky, R.L.1
  • 5
    • 0024329881 scopus 로고
    • The biochemistry of P-glycoprotein-mediated multidrug resistance
    • Endicott J. Ling V. The biochemistry of P-glycoprotein-mediated multidrug resistance Annu Rev Biochem 58 1989 137 171
    • (1989) Annu Rev Biochem , vol.58 , pp. 137-171
    • Endicott, J.1    Ling, V.2
  • 6
    • 0027474456 scopus 로고
    • How cancer cells evade chemotherapy (Sixteenth Richard and Hinda Rosenthal Foundation Award Lecture)
    • Gottesman M.H. How cancer cells evade chemotherapy (Sixteenth Richard and Hinda Rosenthal Foundation Award Lecture) Cancer Res 53 1993 747 754
    • (1993) Cancer Res , vol.53 , pp. 747-754
    • Gottesman, M.H.1
  • 7
    • 0028224534 scopus 로고
    • Cell biological mechanisms of multidrug resistance in tumors
    • Simon S.M. Schinder M. Cell biological mechanisms of multidrug resistance in tumors Proc Natl Acad Sci USA 91 1994 3497 3504
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3497-3504
    • Simon, S.M.1    Schinder, M.2
  • 8
    • 0022891340 scopus 로고
    • Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • Dvorak H.F. Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing N Engl J Med 315 1986 1650 1659
    • (1986) N Engl J Med , vol.315 , pp. 1650-1659
    • Dvorak, H.F.1
  • 9
    • 0029411141 scopus 로고
    • Modulation of the organ microenvironment for treatment of cancer metastasis
    • Fidler I.J. Modulation of the organ microenvironment for treatment of cancer metastasis J Natl Cancer Inst 87 1995 1588 1592
    • (1995) J Natl Cancer Inst , vol.87 , pp. 1588-1592
    • Fidler, I.J.1
  • 10
    • 0029353166 scopus 로고
    • Tumor stroma as a regulator of neoplastic behaviour
    • Iozzo R.V. Tumor stroma as a regulator of neoplastic behaviour Lab Invest 73 1995 157 160
    • (1995) Lab Invest , vol.73 , pp. 157-160
    • Iozzo, R.V.1
  • 11
    • 85114551030 scopus 로고
    • Cell-to-cell contact and extracellular matrix
    • Horwitz A.F. Thiery J.P. Cell-to-cell contact and extracellular matrix Cell Biol 6 1994 205 207
    • (1994) Cell Biol , vol.6 , pp. 205-207
    • Horwitz, A.F.1    Thiery, J.P.2
  • 12
    • 0025852120 scopus 로고
    • The role of stromal cells in tumor metastasis. A new link
    • Van den Hoof A. The role of stromal cells in tumor metastasis. A new link Cancer Cells 3 1991 186 187
    • (1991) Cancer Cells , vol.3 , pp. 186-187
    • Van den Hoof, A.1
  • 13
    • 0027333411 scopus 로고
    • Tumor cell interactions with extracellular matrix during invasion and metastasis
    • Stetler-Stevenson W.G. Aznavoorian S. Liotta L.A. Tumor cell interactions with extracellular matrix during invasion and metastasis Annu Rev Cell Biol 9 1993 541 573
    • (1993) Annu Rev Cell Biol , vol.9 , pp. 541-573
    • Stetler-Stevenson, W.G.1    Aznavoorian, S.2    Liotta, L.A.3
  • 14
    • 0028557342 scopus 로고
    • Extracellular matrix-dependent tissue specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction
    • Roskelly C.D. Desprez P.Y. Bissel M.J. Extracellular matrix-dependent tissue specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction Proc Natl Acad Sci USA 91 1994 12378 12382
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12378-12382
    • Roskelly, C.D.1    Desprez, P.Y.2    Bissel, M.J.3
  • 15
    • 0029980518 scopus 로고    scopus 로고
    • Modulation of transforming growth factor ß receptor levels on microvascular endothelial cells during in vitro angiogenesis
    • Sankar S. Mahooti-Brooks N. Bensen L. Modulation of transforming growth factor ß receptor levels on microvascular endothelial cells during in vitro angiogenesis J Clin Invest 97 1996 1436 1446
    • (1996) J Clin Invest , vol.97 , pp. 1436-1446
    • Sankar, S.1    Mahooti-Brooks, N.2    Bensen, L.3
  • 16
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease Nature Med 1 1995 27 31
    • (1995) Nature Med , vol.1 , pp. 27-31
    • Folkman, J.1
  • 17
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis-dependent?
    • Folkman J. What is the evidence that tumors are angiogenesis-dependent? J Natl Cancer Inst 82 1989 4 6
    • (1989) J Natl Cancer Inst , vol.82 , pp. 4-6
    • Folkman, J.1
  • 18
    • 0028114985 scopus 로고
    • The implications of angiogenesis for the biology and therapy of cancer metastasis
    • Fidler I.J. Ellis L.M. The implications of angiogenesis for the biology and therapy of cancer metastasis Cell 29 1994 185 188
    • (1994) Cell , vol.29 , pp. 185-188
    • Fidler, I.J.1    Ellis, L.M.2
  • 19
    • 84975525035 scopus 로고
    • Clinical applications of research on angiogenesis
    • Folkman J. Clinical applications of research on angiogenesis N Engl J Med 333 1995 1757 1763
    • (1995) N Engl J Med , vol.333 , pp. 1757-1763
    • Folkman, J.1
  • 20
    • 85114552109 scopus 로고
    • Association between tumor angiogenesis and tumor cell shedding into effluent venous blood during breast cancer surgery
    • McCulloch P. Choy A. Martin L. Association between tumor angiogenesis and tumor cell shedding into effluent venous blood during breast cancer surgery Lancet 96 1995 1696 1697
    • (1995) Lancet , vol.96 , pp. 1696-1697
    • McCulloch, P.1    Choy, A.2    Martin, L.3
  • 21
    • 0030020131 scopus 로고    scopus 로고
    • Tumor angiogenesis and tissue factor
    • Folkman J. Tumor angiogenesis and tissue factor Nature Med 2 1996 167 168
    • (1996) Nature Med , vol.2 , pp. 167-168
    • Folkman, J.1
  • 22
    • 0028153751 scopus 로고
    • Isolation and identification of fresh tumor-derived endothelial cells from a murine RIF-1 fibrosarcoma
    • Modzelewski R.A. Davies P. Watkins S.C. Isolation and identification of fresh tumor-derived endothelial cells from a murine RIF-1 fibrosarcoma Cancer Res 54 1994 336 339
    • (1994) Cancer Res , vol.54 , pp. 336-339
    • Modzelewski, R.A.1    Davies, P.2    Watkins, S.C.3
  • 23
    • 0025717523 scopus 로고
    • Inhibition of tumor angiogenesis as a strategy to circumvent acquired resistance to anti-cancer therapeutic agents
    • Kerbel R.S. Inhibition of tumor angiogenesis as a strategy to circumvent acquired resistance to anti-cancer therapeutic agents Bio Essays 13 1991 31 36
    • (1991) Bio Essays , vol.13 , pp. 31-36
    • Kerbel, R.S.1
  • 24
    • 0025799689 scopus 로고
    • The current status of targeting tumour vasculature as a means of cancer therapy: An overview
    • Denekamp J. The current status of targeting tumour vasculature as a means of cancer therapy: An overview Int J Radiat 60 1991 401 408
    • (1991) Int J Radiat , vol.60 , pp. 401-408
    • Denekamp, J.1
  • 25
    • 0027848781 scopus 로고
    • Relationship of endothelial cell proliferation to tumor vascularity in human breast cancer
    • Fox S.B. Gatter C. Bicknell R. Relationship of endothelial cell proliferation to tumor vascularity in human breast cancer Cancer Res 53 1993 4161 4163
    • (1993) Cancer Res , vol.53 , pp. 4161-4163
    • Fox, S.B.1    Gatter, C.2    Bicknell, R.3
  • 26
    • 0029611184 scopus 로고
    • Up-regulation of endoglin on vascular endothelial cells in human solid tumors: Implications for diagnosis and therapy
    • Burrows F.J. Derbyshire J. Tazzari P.L. Up-regulation of endoglin on vascular endothelial cells in human solid tumors: Implications for diagnosis and therapy Clin Cancer Res 1 1995 1632 1634
    • (1995) Clin Cancer Res , vol.1 , pp. 1632-1634
    • Burrows, F.J.1    Derbyshire, J.2    Tazzari, P.L.3
  • 28
    • 0025071180 scopus 로고
    • Expression of the multidrug resistance gene product (P–glycoprotein) in human normal and tumor tissues
    • Cordon-Cardo C. O’Brein J.P. Boccia J. Expression of the multidrug resistance gene product (P–glycoprotein) in human normal and tumor tissues J Histochem Cytochem 38 1990 1277 1287
    • (1990) J Histochem Cytochem , vol.38 , pp. 1277-1287
    • Cordon-Cardo, C.1    O’Brein, J.P.2    Boccia, J.3
  • 29
    • 0025048493 scopus 로고
    • An immunohisto-chemical study of Pi class glutathione S-transferase expression in normal human tissues
    • Terrier P. Townsend A.J. Coindre J.M. An immunohisto-chemical study of Pi class glutathione S-transferase expression in normal human tissues Am J Pathol 137 1990 845 853
    • (1990) Am J Pathol , vol.137 , pp. 845-853
    • Terrier, P.1    Townsend, A.J.2    Coindre, J.M.3
  • 30
    • 0028783268 scopus 로고
    • Predictive and prognostic markers in a series of patients with head and neck squamous cell invasive carcinoma treated with concurrent chemoradiation therapy
    • Gasparini G. Bevilacqua P. Bonoldi E. Predictive and prognostic markers in a series of patients with head and neck squamous cell invasive carcinoma treated with concurrent chemoradiation therapy Clin Cancer Res 1 1995 1375 1383
    • (1995) Clin Cancer Res , vol.1 , pp. 1375-1383
    • Gasparini, G.1    Bevilacqua, P.2    Bonoldi, E.3
  • 31
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: Therapeutic implications N Engl J Med 285 1971 1182 1186
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 32
    • 0028028308 scopus 로고
    • Angiogenesis inhibitors; A review
    • Auerbach W. Auerbach R. Angiogenesis inhibitors; A review Pharmacol Ther 63 1994 265 311
    • (1994) Pharmacol Ther , vol.63 , pp. 265-311
    • Auerbach, W.1    Auerbach, R.2
  • 33
    • 8944249296 scopus 로고    scopus 로고
    • A phase I clinical and pharmacokinetic study of the angiogenesis inhibitor, tecogalan sodium
    • Eckhardt S.G. Burris H.A. Eckhardt J.R. A phase I clinical and pharmacokinetic study of the angiogenesis inhibitor, tecogalan sodium Ann Oncol 7 5 1996 491 496 (this issue)
    • (1996) Ann Oncol , vol.7 , Issue.5 , pp. 491-496
    • Eckhardt, S.G.1    Burris, H.A.2    Eckhardt, J.R.3
  • 34
    • 0026736833 scopus 로고
    • The FGF family of growth factors and oncogenes
    • Basilico C. Moscatelli D. The FGF family of growth factors and oncogenes Adv Cancer Res 59 1992 115 165
    • (1992) Adv Cancer Res , vol.59 , pp. 115-165
    • Basilico, C.1    Moscatelli, D.2
  • 35
    • 85114532932 scopus 로고
    • Structural and functional diversity in FGF receptor multigene family
    • Johnson D.E. Williams L.T. Structural and functional diversity in FGF receptor multigene family Adv Cancer Res 66 1993 1095 1104
    • (1993) Adv Cancer Res , vol.66 , pp. 1095-1104
    • Johnson, D.E.1    Williams, L.T.2
  • 36
    • 0027987884 scopus 로고
    • Interaction of high molecular weight basic fibroblast growth factor (bFGF) with endothelium: Biological activity and intracellular fate of human recombinant Mr24,000 bFGF
    • Gualandris A. Urbinati C. Rusnati M. Interaction of high molecular weight basic fibroblast growth factor (bFGF) with endothelium: Biological activity and intracellular fate of human recombinant Mr24,000 bFGF J Cell Physiol 161 1994 149 159
    • (1994) J Cell Physiol , vol.161 , pp. 149-159
    • Gualandris, A.1    Urbinati, C.2    Rusnati, M.3
  • 37
    • 0022977366 scopus 로고
    • Both normal and tumor cells produce basic fibroblast growth factor
    • Moscatelli D. Presta M. Joseph-Silverstein J. Both normal and tumor cells produce basic fibroblast growth factor J Cell Physiol 129 1986 273 276
    • (1986) J Cell Physiol , vol.129 , pp. 273-276
    • Moscatelli, D.1    Presta, M.2    Joseph-Silverstein, J.3
  • 38
    • 0026319891 scopus 로고
    • Suppression of solid tumor growth by immunoneutralizing monoclonal antibody against human basic fibroblast growth factor
    • Hori A. Sasada R. Matsutani E. Suppression of solid tumor growth by immunoneutralizing monoclonal antibody against human basic fibroblast growth factor Cancer Res 51 1991 6180 6184
    • (1991) Cancer Res , vol.51 , pp. 6180-6184
    • Hori, A.1    Sasada, R.2    Matsutani, E.3
  • 39
    • 85114523932 scopus 로고    scopus 로고
    • Interaction of angiogenic basic fibroblast growth factor with endothelial cell heparan sulfate proteoglycans: Biological implications in neovascularization
    • Rusnati M. Presta M. Interaction of angiogenic basic fibroblast growth factor with endothelial cell heparan sulfate proteoglycans: Biological implications in neovascularization Int J Clin Lab Res 1996 in press
    • (1996)
    • Rusnati, M.1    Presta, M.2
  • 40
    • 0025291743 scopus 로고
    • In situ detection of basic fibroblast growth factor by highly specific antibodies
    • Schulze-Osthoff K. Risau W. Vollmer E. In situ detection of basic fibroblast growth factor by highly specific antibodies Am J Pathol 137 1990 85 92
    • (1990) Am J Pathol , vol.137 , pp. 85-92
    • Schulze-Osthoff, K.1    Risau, W.2    Vollmer, E.3
  • 41
    • 0029587247 scopus 로고
    • Endothelial growth factors; A target for antiangiogenesis
    • Toi M. Endothelial growth factors; A target for antiangiogenesis Cancer J 8 1995 315 319
    • (1995) Cancer J , vol.8 , pp. 315-319
    • Toi, M.1
  • 42
    • 0028328983 scopus 로고
    • Elevated levels of an angiogenic peptide, basic fibroblast growth factor in the urine of patients with a wide spectrum of cancers
    • Nguyen M. Watanabe H. Budson A.E. Elevated levels of an angiogenic peptide, basic fibroblast growth factor in the urine of patients with a wide spectrum of cancers J Natl Cancer Inst 86 1994 356 361
    • (1994) J Natl Cancer Inst , vol.86 , pp. 356-361
    • Nguyen, M.1    Watanabe, H.2    Budson, A.E.3
  • 43
    • 0028939826 scopus 로고
    • Clinical implications of the determination of tumor angiogenesis in breast carcinoma: Much more than a new prognostic tool
    • Gasparini G. Harris A.L. Clinical implications of the determination of tumor angiogenesis in breast carcinoma: Much more than a new prognostic tool J Clin Oncol 13 1995 765 782
    • (1995) J Clin Oncol , vol.13 , pp. 765-782
    • Gasparini, G.1    Harris, A.L.2
  • 44
    • 0028305809 scopus 로고
    • Potentiation of cytotoxic cancer therapies by TNP-470 alone and with other antiangiogenic agents
    • Teicher B.A. Holden S.A. Ara G. Potentiation of cytotoxic cancer therapies by TNP-470 alone and with other antiangiogenic agents Int J Cancer 57 1994 920 925
    • (1994) Int J Cancer , vol.57 , pp. 920-925
    • Teicher, B.A.1    Holden, S.A.2    Ara, G.3
  • 45
    • 0028263197 scopus 로고
    • Does improved control of tumour growth require an anti-cancer therapy targeting both neoplastic and intratumoral endothelial cells?
    • Gasparini G. Harris A.L. Does improved control of tumour growth require an anti-cancer therapy targeting both neoplastic and intratumoral endothelial cells? Eur J Cancer 30A 1994 201 206
    • (1994) Eur J Cancer , vol.30A , pp. 201-206
    • Gasparini, G.1    Harris, A.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.