Role of glycation in human lens protein structure change

European Journal of Ophthalmology

Volumn 6, Issue 2, 1996, Pages 155-161

  Ramalho, J S ^a   Marques, C ^a   Pereira, P C ^a   Mota, M C ^a,b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b Biomed Inst Res Light and Image   (Portugal)

Author keywords

Amino acids; Cataract; Crystallin; Fluorescence; Glycation; Lens

Indexed keywords

AMINO ACID; CRYSTALLIN;

AGED; ARTICLE; CATARACT; CONTROLLED STUDY; DIABETES MELLITUS; FLUORESCENCE; GLYCATION; HUMAN; HUMAN TISSUE; LENS; PRIORITY JOURNAL;

EID: 0030035489     PISSN: 11206721     EISSN: None     Source Type: Journal    
DOI: 10.1177/112067219600600211     Document Type: Article

References (27)

1. Sell DR, Monnier VM. Structure elucidation of a senescence cross-link from human extracellular matrix. Implication of pentoses in the aging process. J Biol Chem 1989; 264: 21597-602.
2. Asghar A, Henrickson RL. Chemical, biochemical, functional, and nutritional characteristics of collagen in food systems. Adv Food Res 1982; 28: 231-372.
3. Mota MC, Carvalho P, Ramalho JS, Cardoso E, Gaspar AM, Abreu G. Protein glycation and in vivo distribution of human lens fluorescence. Int Ophthalmol 1995; 18: 187-93.
4. Kasai K, Nakamura T, Kase N, et al. Increased glycosylation of proteins from cataractous lenses in diabetes. Diabetologia 1983; 25: 36-8.
5. Lee JH, Shin DH, Lupovitch A, Shi DX. Glycosylation of lens proteins in senile cataract and diabetes mellitus. Biochem Biophys Res Commun 1984; 123: 888-93.
6. Pande A, Garner WH, Spector A. Glucosylation of human lens protein and cataractogenesis. Biochem Biophys Res Commun 1979; 89: 1260-6.
7. Oimomi M, Maeda Y, Hata F, et al. Glycation of cataractous lens in non-diabetic senile subjects and in diabetic patients. Exp Eye Res 1988; 46: 415-20.
8. Perry RE, Swamy MS, Abraham EC. Progressive changes in lens crystallin glycation and high-molecular-weight aggregate formation leading to cataract development in streptozotocin-diabetic rats. Exp Eye Res 1987; 44: 269-82.
9. Stevens VJ, Rouzer CA, Monnier A, Cerami A. Diabetic cataract formation: potential role of glycosylation of lens crystallins. Proc Natl Acad Sci USA 1978; 75: 2918-22.
10. Heinrikson M, Meredith J. Amino acid analysis by reverse phase high performance liquid chromatography: precolumn derivatization with phenylisothiocyanate. Anal Biochem 1984; 136: 65-74.
11. Allen G. Laboratory techniques in biochemistry and molecular biology. Sequencing of proteins and peptides. Burdon RH, van Knippenberg PH, ed. Series. Amsterdam: Elsevier, 1989; 425.
12. Schleicher E, Wieland OH. Specific quantitation by HPLC of protein (lysine) bound glucose in human serum albumin and other glycosylated proteins. J Clin Chem Clin Biochem 1981; 19: 81-7.
13. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the folin phenol reagent. J Biol Chem 1951; 193: 265-75.
14. Peterson GL. Review of the folin protein quantitation method of Lowry, Rosebrough, Farr and Randall. Anal Biochem 1979; 100: 201-15.
15. Ansari NH, Awarthi YC, Srivastava SK. Role of glycosylation in protein disulfide formation and cataractogenesis. Exp Eye Res 1980; 31: 9-19.
16. Nagaraj RH, Monnier VM. Isolation and characterization of a blue fluorophone from human eye lens crystallins: in vitro formation from Maillard reaction with ascorbate and ribose. Biochem Biophys Acta 1992; 1116: 34-42.
17. Pirie A. Color and solubility of the proteins of human cataracts. Invest Ophthalmol Vis Sci 1968; 7: 634-50
18. Pirie A. Formation of N-formyl kynurenine in proteins from lens and other sources by exposure to sunlight. Biochem J 1971; 125: 203-8.
19. Kamei A. Possible process of insolubilization of lens proteins-direct effect of glucose. Exp Eye Res 1991; 52: 369-74.
20. Beswick HT, Harding JJ. Conformational changes induced in lens alpha- and gamma-crystallins by modification with glucose 6-phosphate. Biochem J 1987; 246: 761-9.
21. Granhee S, Monnier VM. Mechanism of formation of the Maillard protein cross-link pentosidine. Glucose, frutose and ascorbate as pentosidine precursors. J Biol Chem 1991; 266: 11649-53.
22. Deyer DG, Blackledge JA, Thorpe SR. Baynes JW. Formation of pentosidine during nonenzymatic browing of proteins by glucose. J Biol Chem 1991; 266: 11654-60.
23. Bensch KG, Fleming JE, Lohmann W. The role of ascorbic acid in senile cataract. Proc Natl Acad Sci USA 1985; 82: 7193-6.
24. Ortwerth BJ, Olesen PR. Ascorbic acid-induced crosslinking of lens proteins: evidence supporting a Maillard reaction. Biochim Biophys Acta 1988; 956: 10-22.
25. Garland D, Zigler JJ, Kinoshita J. Structural changes in bovine lens crystalline induced by ascorbate, metal and oxygen. Arch Biochem Biophys 1986; 251: 771-6.
26. Kern HL, Zolot SL. Transport of vitamin C in the lens. Curr Eye Res 1987; 6: 885-96.
27. Heath H. The distribution and possible functions of ascorbic acid in the eye. Exp Eye Res 1962; 1: 362-7.