The chimeric genes AML1/MDS1 and AML1/EAP inhibit AML1B activation at the CSF1R promoter, but only AML1/MDS1 has tumor-promoter properties

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 3, 1996, Pages 1044-1048

  Zent, Clive S ^a   Mathieu, Carol ^a   Claxton, David F ^b   Zhang, Dong Er ^c   Tenen, Daniel G ^c   Rowley, Janet D ^a   Nucifora, Giuseppina ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; COLONY STIMULATING FACTOR 1; GROWTH FACTOR RECEPTOR; TRANSCRIPTION FACTOR; TUMOR PROMOTER;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; FIBROBLAST; GENE REPLICATION; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROMOTER REGION; RAT; REPORTER GENE; TRANSACTIVATION; TUMOR PROMOTION;

ACUTE DISEASE; ANIMALS; BLAST CRISIS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIVISION; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; CHIMERA; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 21; CHROMOSOMES, HUMAN, PAIR 3; CORE BINDING FACTOR ALPHA 2 SUBUNIT; DNA-BINDING PROTEINS; GLYCOGEN SYNTHASE KINASE 3; HUMANS; LEUKEMIA, MYELOID; LEUKEMIA, MYELOID, CHRONIC; MICE; MYELODYSPLASTIC SYNDROMES; NEOPLASM PROTEINS; PROTO-ONCOGENE PROTEINS; RATS; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; RIBOSOMAL PROTEINS; RNA-BINDING PROTEINS; TRANSCRIPTION FACTORS; TRANSFECTION; TRANSLOCATION, GENETIC;

ANIMALIA; EUKARYOTA; MURINAE; MUS MUSCULUS;

EID: 0030034804     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.3.1044     Document Type: Article

References (26)

1. Nucifora, G., Birn, D. J., Espinosa, R., Erickson, P., LeBeau, M. M., Roulston, D., McKeithan, T. W., Drabkin, H. & Rowley, J. D. (1993) Blood 81, 2728-2734.
2. Miyoshi, H., Shimizu, K., Kozu, T., Maseki, N., Kaneko, Y. & Ohki, M. (1991) Proc. Natl. Acad. Sci. USA 88, 10431-10434.
3. Ogawa, E., Maruyama, M., Kagoshima, H., Inuzuka, M., Lu. J., Satake, M., Shigesada, K. & Ito, Y. (1993) Proc. Natl. Acad. Sci. USA 90, 6859-6863.
4. Ogawa, E., Inuzuka, M., Maruyama, M., Satake, M., Fujimoto, M. N., Ito, Y. & Shigesada, K. (1993) Virology 194, 314-331.
5. Meyers, S., Downing, J. R. & Hiebert, S. W. (1993) Mol. Cell. Biol. 13, 6336-6345.
6. Nuchprayoon, I., Meyers, S., Scott, L. M., Suzow, J., Hiebert, S. & Friedman, A. D. (1994) Mol. Cell. Biol. 14, 5558-5568.
7. Frank, R., Zhang, J., Hiebert, S., Meyers, S. & Nimer, S. (1994) Blood 84 (Suppl. 1), 229A (abstr.).
8. Zhang, D. E., Fujioka, K., Hetherington, C. J., Shapiro, L. H., Chen, H. M., Look, A. T. & Tenen, D. G. (1994) Mol. Cell. Biol. 14, 8085-8095.
9. Meyers, S., Lenny, N. & Hiebert, S. (1995) Mol. Cell. Biol. 15, 1974-1982.
10. Bae, S. C., Iwai, Y. Y., Ogawa, E., Maruyama, M., Inuzuka, M., Kagoshima, H., Shigesada, K., Satake, M. & Ito, Y. (1993) Oncogene 8, 809-815.
11. Satake, M., Nomura, S., Iwai, Y. Y., Takahama, Y., Hashimoto, Y., Niki, M., Kitamura, Y. & Ito, Y. (1995) Mol. Cell. Biol. 15, 1662-1670.
12. Levanon, D., Negreanu, V., Bernstein, Y., Bar-Am, I., Avivi, L. & Groner, Y. (1994) Genomics 23, 425-432.
13. Giese, K., Kingsley, C., Kirshner, J. R. & Grosschedl, R. (1995) Genes Dev. 9, 995-1008.
14. Zhang, D., Hetherington, C. J., Chen, H. & Tenen, D. G. (1994) Mol. Cell. Biol. 14, 373-381.
15. Sherr, C. J. (1990) Blood 75, 1-12.
16. Roussel, M. F., Downing, J. R., Rettenmier, C. W. & Sherr, C. J. (1988) Cell 55, 979-988.
17. Ridge, S. A., Worwood, M., Oscier, D., Jacobs, A. & Padua, R. A. (1990) Proc. Natl. Acad. Sci. USA 87, 1377-1380.
18. Nucifora, G., Begy, C. R., Kobayashi, H., Roulston, D., Claxton, D., Pedersen-Bjergaard, J., Parganas, E., Ihle, J. N. & Rowley, J. D. (1994) Proc. Natl. Acad. Sci. USA 91, 4004-4008.
19. Sacchi, N., Nisson, P. E., Watkins, P. C., Faustinella, F., Wijsman, J. & Hagemeijer, A. (1994) Genes Chromosomes Cancer 11, 226-236.
20. Nucifora, G., Begy, C. R., Erickson, P., Drabkin, H. A. & Rowley, J. D. (1993) Proc Natl. Acad. Sci. USA 90, 7784-7788.
21. Mitani, K., Ogawa, S., Tanaka, T., Miyoshi, H., Kurokawa, M. K., Mano, H., Yazaki, Y., Ohki, M. & Harai, H. (1994) EMBO J. 13, 504-510.
22. Claxton, D. F., Liu, P., Hsu, H. B., Marlton, P., Hester, J., Collins, F., Deisseroth, A. B., Rowley, J. D. & Sciciliano, M. J. (1994) Blood 83, 1750-1756.
23. Denizot, F. & Lang, R. (1986) J. Immunol. Methods 89, 271-277.
24. Bae, S. C., Ogawa, E., Maruyama, M., Oka, H., Satake, M., Shigesada, K., Jenkins, N. A., Gilbert, D. J., Copeland, N. G. & Ito, Y. (1994) Mol. Cell. Biol. 14, 3242-3252.
25. Van Roy, F. M., Messiaen, L., Liebaut, G., Gao, J., Dragonetti, G. H., Fiers, W. C. & Mareel, M. M. (1986) Cancer Res. 46, 4787-4795.
26. Reynolds, V. L., DiPietro, M., Lebovitz, R. M. & Lieberman, M. W. (1987) Cancer Res. 47, 6384-6387.