Activation of NFkB and potential ion of TNF-induced NFkB activation by ceramide analogues in leukemic cell lines despite the absence of an observed sphingomyelinase signalling event

Biochemical Society Transactions

Volumn 24, Issue 1, 1996, Pages

  Boland, Marion P ^a,b   Foster, Steven J ^a   O'Neill, Luke A J ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1 PHENYL 2 PALMITOYLAMINO 3 MORPHOLINO 1 PROPANOL; 1-PHENYL-2-PALMITOYLAMINO-3-MORPHOLINO-1-PROPANOL; CERAMIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOENZYME; MORPHOLINE DERIVATIVE; SPHINGOLIPID; SPHINGOMYELIN PHOSPHODIESTERASE; TUMOR NECROSIS FACTOR ALPHA; CERAMIDE DERIVATIVE; TUMOR NECROSIS FACTOR;

ARTICLE; CELL STRAIN HL 60; ENZYME ACTIVATION; HUMAN; KINETICS; METABOLISM; SIGNAL TRANSDUCTION; CELL ACTIVITY; CONFERENCE PAPER; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

CERAMIDES; ENZYME ACTIVATION; HL-60 CELLS; HUMANS; ISOENZYMES; KINETICS; MORPHOLINES; NF-KAPPA B; SIGNAL TRANSDUCTION; SPHINGOLIPIDS; SPHINGOMYELIN PHOSPHODIESTERASE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030034546     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Heller, R.A. and Kronke, M. (1994). J.Cell.Biol., 126, 5-9.
2. Kirn, M-Y. Linardic., C., Obeid, L. and Hannun, Y. (1991) J.Biol.Chem., 266, 484-489.
3. Dressier, K.A., Mathias, S. and Kolesnick, R.N. (1992) Science, 255, 1715-1718.
4. Schutze. S., Potthoff, K., Machleidt, T., Berkovic, D., Wiegmann, K. and Kronke, M. (1992) Cell, 71,765-776.
5. Wiegmann, K., Schütze, S., Machleidt, T., Witte, D. and Kronke, M. (1994) J.Biol.Chem., 268, 20520-20523.
6. Hannun, Y.A. (1994) J.Biol.Chem., 269, 3125-3128.
7. Kono, K., Sukegawa, K., Ishikawa, Y., Orii, T. and Matsushima, K. (1994) Int. Inununol., 6, 1269-1272.
8. Dbaibo, O.S., Obeid, UM. and Hannun, Y.A. (1993) J.Biol.Cbem., 268, 17762-17766.
9. Abe, A., Inokuchi, J-I., Jimbo. M., Shimeno, H., Nagamatsu, A., Shayman, J.A., Shukla, O.S. and Radin, N.S. (1992)
10. J. Biochem., 111, 191-196.
11. Grimm, S. and Baeuerle, P.A. (1993) Biochem. J., 108, 525-530.
12. Betts, J.C., Agranoff, A.B., Nabel., GJ. and Shayman, J.A. (1994) J.Biol.Chem., 269, 8455-8458.
13. Osbora, U Kunkel, S. and Nabel, G.J. (1989) Proc.Natl.Acad.Sci. USA, 86, 2336-2340.