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Volumn 75, Issue 1, 1996, Pages 70-75

Mutations which introduce free cysteine residues in the Gla-domain of vitamin K dependent proteins result in the formation of complexes with α1-microglobulin

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 MICROGLOBULIN; BLOOD CLOTTING FACTOR; BLOOD CLOTTING FACTOR 9; CALCIUM; CYSTEINE; PROTEIN C; PROTHROMBIN; VITAMIN K GROUP;

EID: 0030034473     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0038-1650223     Document Type: Article
Times cited : (26)

References (32)
  • 1
    • 0024292694 scopus 로고
    • The molecular basis of blood coagulation
    • Furie B, Furie BC. The molecular basis of blood coagulation. Cell 1988; 53: 505-18.
    • (1988) Cell , vol.53 , pp. 505-518
    • Furie, B.1    Furie, B.C.2
  • 2
    • 0027499804 scopus 로고
    • Synthesis of vitamin K-dependent proteins
    • Suttie JW. Synthesis of vitamin K-dependent proteins. FASEB J 1993; 7: 445-52.
    • (1993) FASEB J , vol.7 , pp. 445-452
    • Suttie, J.W.1
  • 5
    • 0017620768 scopus 로고
    • Vitamin K-dependent formation of γ-carboxyglutamic acid
    • Stenflo J, Suttie JW. Vitamin K-dependent formation of γ-carboxyglutamic acid. Ann Rev Biochem 1977; 46: 157-72.
    • (1977) Ann Rev Biochem , vol.46 , pp. 157-172
    • Stenflo, J.1    Suttie, J.W.2
  • 6
    • 0021099497 scopus 로고
    • 2+ binding to a high affinity site that does not contain γ-carboxyglutamic acid
    • 2+ binding to a high affinity site that does not contain γ-carboxyglutamic acid. J Biol Chem 1983; 258: 5554-60.
    • (1983) J Biol Chem , vol.258 , pp. 5554-5560
    • Johnson, A.E.1    Esmon, N.L.2    Laue, T.M.3    Esmon, C.T.4
  • 7
    • 0023239941 scopus 로고
    • The factor IX phospholipid-binding site is required for calcium-dependent activation of factor IX by factor XIa
    • Liebman HA, Furie BC, Furie B. The factor IX phospholipid-binding site is required for calcium-dependent activation of factor IX by factor XIa. J Biol Chem 1987; 262: 7605-12.
    • (1987) J Biol Chem , vol.262 , pp. 7605-7612
    • Liebman, H.A.1    Furie, B.C.2    Furie, B.3
  • 8
    • 0023020122 scopus 로고
    • Prothrombin requires two sequential metal-dependent conformational transitions to bind phospholipid. Conformation-specific antibodies directed against the phospholipid-binding site on prothrombin
    • Borowski M, Furie BC, Bauminger S, Furie B. Prothrombin requires two sequential metal-dependent conformational transitions to bind phospholipid. Conformation-specific antibodies directed against the phospholipid-binding site on prothrombin. J Biol Chem 1986; 261: 14969-75.
    • (1986) J Biol Chem , vol.261 , pp. 14969-14975
    • Borowski, M.1    Furie, B.C.2    Bauminger, S.3    Furie, B.4
  • 9
    • 0025598301 scopus 로고
    • 7D) of human activated protein C displays greatly reduced activity as an anticoagulant
    • 7D) of human activated protein C displays greatly reduced activity as an anticoagulant. Biochemistry 1990; 29: 10828-34.
    • (1990) Biochemistry , vol.29 , pp. 10828-10834
    • Zhang, L.1    Castellino, F.J.2
  • 10
    • 0026687609 scopus 로고
    • Role of individual γ-carboxyglutamic acid residues of activated human protein C in defining its in vitro anticoagulant activity
    • Zhang L, Jhingan A, Castellino FJ. Role of individual γ-carboxyglutamic acid residues of activated human protein C in defining its in vitro anticoagulant activity. Blood 1992; 80: 942-52.
    • (1992) Blood , vol.80 , pp. 942-952
    • Zhang, L.1    Jhingan, A.2    Castellino, F.J.3
  • 11
    • 0027085666 scopus 로고
    • Influence of specific γ-carboxyglutamic acid residues on the integrity of the calcium-dependent conformation of human protein C
    • Zhang L, Castellino FJ. Influence of specific γ-carboxyglutamic acid residues on the integrity of the calcium-dependent conformation of human protein C. J Biol Chem 1992; 267: 26078-84.
    • (1992) J Biol Chem , vol.267 , pp. 26078-26084
    • Zhang, L.1    Castellino, F.J.2
  • 12
    • 0028670884 scopus 로고
    • Functions of individual γ-carboxyglutamic acid (Gla) residues of human protein C. Determination of functionally nonessential Gla residues and correlations with their mode of binding to calcium
    • Christiansen WT, Tulinsky A, Castellino FJ. Functions of individual γ-carboxyglutamic acid (Gla) residues of human protein C. Determination of functionally nonessential Gla residues and correlations with their mode of binding to calcium. Biochemistry 1994; 33: 14993-5000.
    • (1994) Biochemistry , vol.33 , pp. 14993-15000
    • Christiansen, W.T.1    Tulinsky, A.2    Castellino, F.J.3
  • 13
    • 0027155692 scopus 로고
    • The contributions of individual γ-carboxyglutamic acid residues in the calcium-dependent binding of recombinant human protein C to acidic phospholipid vesicles
    • Zhang L, Castellino FJ. The contributions of individual γ-carboxyglutamic acid residues in the calcium-dependent binding of recombinant human protein C to acidic phospholipid vesicles. J Biol Chem 1993; 268: 12040-45.
    • (1993) J Biol Chem , vol.268 , pp. 12040-12045
    • Zhang, L.1    Castellino, F.J.2
  • 14
    • 0027358796 scopus 로고
    • The importance of specific γ-carboxyglutamic acid residues in prothrombin. Evaluation by site-specific mutagenesis
    • Ratcliffe JV, Furie B, Furie BC. The importance of specific γ-carboxyglutamic acid residues in prothrombin. Evaluation by site-specific mutagenesis. J Biol Chem 1993; 268: 24339-45.
    • (1993) J Biol Chem , vol.268 , pp. 24339-24345
    • Ratcliffe, J.V.1    Furie, B.2    Furie, B.C.3
  • 18
    • 9044233525 scopus 로고
    • Identification of two deletions and four point mutations in the protein C gene of 6 unrelated Spanish patients with hereditary protein C deficiency
    • Sala N, Poort SR, Bertina RM, Soria JM, Fontcuberta J. Identification of two deletions and four point mutations in the protein C gene of 6 unrelated Spanish patients with hereditary protein C deficiency. Thromb Haemost 1991; 65: 1197.
    • (1991) Thromb Haemost , vol.65 , pp. 1197
    • Sala, N.1    Poort, S.R.2    Bertina, R.M.3    Soria, J.M.4    Fontcuberta, J.5
  • 19
    • 0028650365 scopus 로고
    • Homozygosity for a novel missense mutation in the prothrombin gene causing a severe bleeding disorder
    • Poort SR, Michiels JJ, Reitsma PH, Bertina RM. Homozygosity for a novel missense mutation in the prothrombin gene causing a severe bleeding disorder. Thromb Haemost 1994; 72: 819-24.
    • (1994) Thromb Haemost , vol.72 , pp. 819-824
    • Poort, S.R.1    Michiels, J.J.2    Reitsma, P.H.3    Bertina, R.M.4
  • 21
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680-5.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 22
    • 0019800463 scopus 로고
    • Silver stain for proteins in polyacrylamide gels, a modified procedure with enhanced uniform sensitivity
    • Morrissey JH. Silver stain for proteins in polyacrylamide gels, a modified procedure with enhanced uniform sensitivity. Anal Biochem 1981; 117: 307-10.
    • (1981) Anal Biochem , vol.117 , pp. 307-310
    • Morrissey, J.H.1
  • 23
    • 0018899021 scopus 로고
    • Pathways in the activation of coagulation factor X
    • Mertens K, Bertina RM. Pathways in the activation of coagulation factor X. Biochem J 1980; 185: 647-58.
    • (1980) Biochem J , vol.185 , pp. 647-658
    • Mertens, K.1    Bertina, R.M.2
  • 24
    • 0022450813 scopus 로고
    • Molecular basis of hemophilia B: A defective enzyme due to an unprocessed propeptide is caused by a point mutation in the factor IX precursor
    • Diuguid DL, Rabiet MJ, Furie BC, Liebman HA, Furie B. Molecular basis of hemophilia B: A defective enzyme due to an unprocessed propeptide is caused by a point mutation in the factor IX precursor. Proc Natn Acad Sci USA 1986; 83: 5803-7.
    • (1986) Proc Natn Acad Sci USA , vol.83 , pp. 5803-5807
    • Diuguid, D.L.1    Rabiet, M.J.2    Furie, B.C.3    Liebman, H.A.4    Furie, B.5
  • 26
    • 0023609533 scopus 로고
    • 1-acid glycoprotein and serum retinol-binding protein and its relatives
    • 1-acid glycoprotein and serum retinol-binding protein and its relatives. FASEB J 1987; 1: 209-14.
    • (1987) FASEB J , vol.1 , pp. 209-214
    • Pervaiz, S.1    Brew, K.2
  • 27
    • 0028057820 scopus 로고
    • Location of a novel type of interpolypeptide chain linkage in the human protein HC-IgA complex (HC-IgA) and identification of a heterogeneous chromophore associated with the complex
    • Calero M, Escribano J, Grubb A, Méndez E. Location of a novel type of interpolypeptide chain linkage in the human protein HC-IgA complex (HC-IgA) and identification of a heterogeneous chromophore associated with the complex. J Biol Chem 1994; 269: 384-9.
    • (1994) J Biol Chem , vol.269 , pp. 384-389
    • Calero, M.1    Escribano, J.2    Grubb, A.3    Méndez, E.4
  • 29
    • 0025056635 scopus 로고
    • Endoproteolytic processing of the dibasic cleavage site in the human protein C precursor in transfected mammalian cells: Effects of sequence alterations on efficiency of cleavage
    • Foster DC, Sprecher CA, Holly RD, Gambee JE, Walker KM, Kumar AA. Endoproteolytic processing of the dibasic cleavage site in the human protein C precursor in transfected mammalian cells: Effects of sequence alterations on efficiency of cleavage. Biochemistry 1990; 29: 347-354.
    • (1990) Biochemistry , vol.29 , pp. 347-354
    • Foster, D.C.1    Sprecher, C.A.2    Holly, R.D.3    Gambee, J.E.4    Walker, K.M.5    Kumar, A.A.6
  • 31
    • 0025881214 scopus 로고
    • Role of the hexapeptide disulfide loop present in the γ-carboxyglutamic acid domain of human protein C in its activation properties and in the in vitro anticoagulant activity of activated protein C
    • Zhang L, Castellino FJ. Role of the hexapeptide disulfide loop present in the γ-carboxyglutamic acid domain of human protein C in its activation properties and in the in vitro anticoagulant activity of activated protein C. Biochemistry 1991; 30: 6696-704.
    • (1991) Biochemistry , vol.30 , pp. 6696-6704
    • Zhang, L.1    Castellino, F.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.