Antikaliuretic action of trimethoprim is minimized by raising urine pH

Kidney International

Volumn 49, Issue 1, 1996, Pages 82-87

  Schreiber, Martin ^b   Schlanger, Lynn E ^b   Chen, Ching Bun ^b   Lessan Pezeshki, Mahboob ^b   Halperin, Mitchell L ^a   Patnaik, Asit ^b   Ling, Brian N ^b   Kleyman, Thomas R ^b  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACETAZOLAMIDE; DEOXYCORTICOSTERONE; TRIMETHOPRIM;

ANIMAL CELL; ARTICLE; IN VITRO STUDY; KALIURESIS; KIDNEY CELL CULTURE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; URINE PH; XENOPUS LAEVIS;

EID: 0030034317     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1038/ki.1996.11     Document Type: Article

References (28)

1. CHOI MJ, FERNANDEZ PC, PATNAIK A, COUTAYE-GERARD B, D'ANDREA D, ZERLIP H, KLEYMAN TR: Trimethoprim induced hyperkalemia in a patient with AIDS. N Engl J Med 328:703-706, 1993
2. KLEYMAN TR, ROBERTS C, LING BN: A mechanism for pentamidine-induced hyperkalemia: Inhibition of distal nephron sodium transport. Ann Intern Med 122:103-106, 1995
3. 6 cells in distal nephron cells. Kidney Int 45:1070-1076, 1994
4. SENEY FD JR, BURNS DK, SILVA FG: Acquired immunodeficiency syndrome and the kidney. Am J Kidney Dis 16:1-13, 1990
5. VAZIRI ND, BARBARI A, LICORISH K, CESARIO T, GUPTA S: Spectrum of renal abnormalities in acquired immunodeficiency syndrome. J Natl Med Assoc 77:369-375, 1985
6. GREENBERG S, REISER IW, CHOU S-Y, PORUSH JG: Trimethoprim-sulfamethoxazole induces reversible hyperkalemia. Ann Intern Med 119:291-295, 1993
7. KLEYMAN TR, CRAGOE EJ JR: The mechanism of action of amiloride. Semin Nephrol 8:242-248, 1988
8. KLEYMAN TR, CRAGOE EJ JR: Cation transport probes: The amiloride series, in Methods in Enzymology. Cellular and Subcellular Transport: Epithelial Cell, edited by FLEISCHER S, FLEISCHER B, Orlando, Academic Press, 1990, pp 739-755
9. EATON DC, MARUNAKA Y: Ion channel fluctuations: "Noise" and single channel measurements, in Current Topics in Membranes and Transport: Channels, Noise and Impedance in Epithelia, edited by HELMAN SI, VAN DRIESSCHE W, New York, Academic Press, 1990, pp 61-114
10. PALMER LG; Epithelial Na channels: The nature of the conducting pore. Renal Physiol Biochem 13:51-58, 1990
11. BENOS DJ, SIMON SA, MANDEL LJ, CALA PM: Effect of amiloride and some of its analogues on cation transport in isolated frog skin and thin lipid membranes. J Gen Physiol 68:43-63, 1976
12. CUTHBERT AW: Importance of guanidinium groups on blocking sodium channels in epithclia. Mol Pharmacol 12:945-957, 1976
13. ROTH B, STRELITZ JZ: The protonalion of 2,4-diaminopyrimidines. Dissociation constants and substituent effects. J Org Chem 34:821-836, 1969
14. + channels in a distal nephron cell line (A6). Am J Physiol 267:C1414-C1425, 1994
15. 6 distal nephron cells. (abstract) J Am Soc Nephrol 4:878, 1993
16. LING BN, HINTON CF, EATON DC: Amiloride-sensitive sodium channels in rabbit cortical collecting tubule primary cultures. Am J Physiol 261:F333-F344, 1991
17. VASUVATTAKUL S, QUAGGIN SE, SCHEICH AM, BAYOUMI A, GOGUEN JM, CHEEMA-DHADLI S, HALPERIN ML: Kaliuretic response to aldosteronc: Influence of potassium in the diet. Am J Kidney Dis 21:152-160, 1993
18. WEST ML, BENDZ O, CHEN CB, SINGER G, RICHARDSON RMA, SONNENBERG H, HALPERIN ML: Development of a test to evaluate the transtubular potassium concentration gradient in the cortical collecting duct in vivo. Miner Electrol Metab 12:226-233, 1986
19. ETHIER JH, KAMEL KS, MAGNER PO, LEMANN JJ, HALPERIN ML: The transtubular potassium concentration in patients with hypokalemia and hyperkalemia. Am J Kidney Dis 15:309-315, 1990
20. KAMEL KS, QUAGGIN S, SCHEICH A, HALPERIN ML: Disorders of potassium homeostasis: An approach based on pathophysiology. Am J Kidney Dis 24:597-613, 1994
21. WRIGHT FS, GIEBISCH G: Regulation of potassium excretion, in The Kidney: Physiology and Pathophysiology, edited by SELDIN DW, GIEBISCH G, New York, Raven Press Ltd., 1992, pp 2209-2247
22. VELAZOUEZ H, WRIGHT FS, GOOD DW: Luminal influences on potassium secretion: Chloride replacement with sulfate. Am J Physiol 242:F46-F55, 1982
23. GREENBERG S, REISER IW, CHOU S-Y: Hyperkalemia with high-dose trimethoprim-sulfamethoxazole therapy. Am J Kidney Dis 22:603-606, 1993
24. VELAZQUEZ H, PERAZELLA MA, WRIGHT FS, ELLISON DH: Renal mechanism of trimethoprim-induced hyperkalemia. Ann Intern Med 119:295-301, 1993
25. ROBERTSON GL: Physiology of ADII secretion. Kidney Int 32(Suppl 21):S20-S26, 1987
26. STEELE A, DE VEBER H, QUAGGIN SE, SCMEICH A, ETHIER J, HALPERIN ML: What is responsible for the diurnal variation in potassium excretion? Am J Physiol 36:R554-R560, 1994
27. SCHREIBER M, HALPERIN ML: Urea excretion rate as a contributor to trimethoprim-induced hyperkalemia. Ann Int Med 120:166-167, 1994
28. HALPERIN ML, JUNGAS RL: Metabolic production and renal disposal of hydrogen ions. Kidney Int 24:709-713, 1983