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Volumn 99, Issue 1-3, 1996, Pages 165-177

Decreased glutathione peroxidase activity in mice in response to nafenopin is caused by changes in selenium metabolism

Author keywords

Glutathione peroxidase; Mice; Nafenopin; Peroxisome proliferators; Selenium; Selenoprotein

Indexed keywords

GLUTATHIONE PEROXIDASE; MESSENGER RNA; NAFENOPIN; PEROXISOME PROLIFERATOR; SELENIUM;

EID: 0030034128     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/0009-2797(95)03667-9     Document Type: Article
Times cited : (10)

References (52)
  • 1
    • 0021051308 scopus 로고
    • Carcinogenesis by hepatic peroxisome proliferators: Evaluation of risk of hypolipidemic drugs and industrial plasticizers to humans
    • J.K. Reddy and N.D. Lalwani, Carcinogenesis by hepatic peroxisome proliferators: evaluation of risk of hypolipidemic drugs and industrial plasticizers to humans, CRC Crit. Rev. Toxicol., 12 (1983) 1-58.
    • (1983) CRC Crit. Rev. Toxicol. , vol.12 , pp. 1-58
    • Reddy, J.K.1    Lalwani, N.D.2
  • 2
    • 0024430314 scopus 로고
    • Oxidative DNA damage caused by persistent peroxisome proliferation: Its role in hepatocarcinogenesis
    • J.K. Reddy and M.S. Rao, Oxidative DNA damage caused by persistent peroxisome proliferation: its role in hepatocarcinogenesis. Mutat. Res., 214 (1989) 63-68.
    • (1989) Mutat. Res. , vol.214 , pp. 63-68
    • Reddy, J.K.1    Rao, M.S.2
  • 3
    • 0024241608 scopus 로고
    • Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14643) in rats
    • D.S. Marsman, R.C. Cattley, J.G. Conway and J.A. Popp, Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14643) in rats, Cancer Res., 48 (1988) 6739-6744.
    • (1988) Cancer Res. , vol.48 , pp. 6739-6744
    • Marsman, D.S.1    Cattley, R.C.2    Conway, J.G.3    Popp, J.A.4
  • 4
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • I. Isseman and S. Green, Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators, Nature, 347 (1990) 645-650.
    • (1990) Nature , vol.347 , pp. 645-650
    • Isseman, I.1    Green, S.2
  • 5
    • 0026730908 scopus 로고
    • The peroxisome proliferator-activated receptor mediates the induction of CYP4A6, a cytochrome-P450 fatty-acid omega-hydroxylase, by clofibric acid
    • A.S. Muerhoff, K.J. Griffin and E.F. Johnson, The peroxisome proliferator-activated receptor mediates the induction of CYP4A6, a cytochrome-P450 fatty-acid omega-hydroxylase, by clofibric acid, J. Biol. Chem., 267 (1992) 19051-19053.
    • (1992) J. Biol. Chem. , vol.267 , pp. 19051-19053
    • Muerhoff, A.S.1    Griffin, K.J.2    Johnson, E.F.3
  • 6
    • 0026541591 scopus 로고
    • The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene
    • J.D. Tugwood, I. Issemann, R.G. Anderson, K.R. Bundell, W.L. McPheat and S. Green, The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene, EMBO J., 11 (1992) 433-439.
    • (1992) EMBO J. , vol.11 , pp. 433-439
    • Tugwood, J.D.1    Issemann, I.2    Anderson, R.G.3    Bundell, K.R.4    McPheat, W.L.5    Green, S.6
  • 7
    • 0027214910 scopus 로고
    • Diverse peroxisome proliferator-activated receptors bind to the peroxisome proliferator-responsive elements of the rat hydratase/ dehydrogenase and fatty acyl-CoA oxidase genes but differentially induce expression
    • S.L. Marcus, K.S. Miyata, B.W. Zhang, S. Subramani, R.A. Rachubinski and J.P. Capone, Diverse peroxisome proliferator-activated receptors bind to the peroxisome proliferator-responsive elements of the rat hydratase/ dehydrogenase and fatty acyl-CoA oxidase genes but differentially induce expression, Proc. Natl. Acad. Sci. USA, 90 (1993) 5723-5727.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5723-5727
    • Marcus, S.L.1    Miyata, K.S.2    Zhang, B.W.3    Subramani, S.4    Rachubinski, R.A.5    Capone, J.P.6
  • 8
    • 0027161015 scopus 로고
    • PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene
    • O. Bardot, T.C. Aldridge, N. Latruffe and S. Green, PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene, Biochem. Biophys. Res. Commun., 192 (1993) 37-45.
    • (1993) Biochem. Biophys. Res. Commun. , vol.192 , pp. 37-45
    • Bardot, O.1    Aldridge, T.C.2    Latruffe, N.3    Green, S.4
  • 9
    • 0024213976 scopus 로고
    • Stimulation of DNA synthesis but not of peroxisomal β-oxidation by nafenopin in primary cultures of marmoset hepatocytes
    • F. Bieri, W. Stäubli, F. Waechter, S. Muakkassah-Kelly and P. Bentley, Stimulation of DNA synthesis but not of peroxisomal β-oxidation by nafenopin in primary cultures of marmoset hepatocytes, Cell Biol. Int. Rep., 12 (1988) 1077-1087.
    • (1988) Cell Biol. Int. Rep. , vol.12 , pp. 1077-1087
    • Bieri, F.1    Stäubli, W.2    Waechter, F.3    Muakkassah-Kelly, S.4    Bentley, P.5
  • 10
    • 0025069871 scopus 로고
    • Effects produced by the non-genotoxic hepatocarcinogen methylclophenopate in dwarf mice: Peroxisome induction uncoupled from DNA synthesis and nuclearity changes
    • J.A. Styles, M.D. Kelly, N.R. Pritchard and J.R. Foster, Effects produced by the non-genotoxic hepatocarcinogen methylclophenopate in dwarf mice: peroxisome induction uncoupled from DNA synthesis and nuclearity changes, Carcinogenesis, 11 (1990) 387-391.
    • (1990) Carcinogenesis , vol.11 , pp. 387-391
    • Styles, J.A.1    Kelly, M.D.2    Pritchard, N.R.3    Foster, J.R.4
  • 11
    • 0027365688 scopus 로고
    • Peroxisomal enzyme induction uncoupled from enhanced DNA synthesis in putative preneoplastic liver foci of rats treated with a single dose of the peroxisome proliferator nafenopin
    • B. Grasl-Kraupp, W. Huber, I. Timmermann-Trosiener and R. Schultehermann, Peroxisomal enzyme induction uncoupled from enhanced DNA synthesis in putative preneoplastic liver foci of rats treated with a single dose of the peroxisome proliferator nafenopin, Carcinogenesis, 14 (1993) 2435-2437.
    • (1993) Carcinogenesis , vol.14 , pp. 2435-2437
    • Grasl-Kraupp, B.1    Huber, W.2    Timmermann-Trosiener, I.3    Schultehermann, R.4
  • 12
    • 0023066133 scopus 로고
    • Comparative study of the enzymatic defence system against oxygen-derived free radicals: The key role of glutathione peroxidase
    • M. Raes, C. Michiels and J. Remacle, Comparative study of the enzymatic defence system against oxygen-derived free radicals: the key role of glutathione peroxidase, Free Rad. Biol. Med., 3 (1987) 3-7.
    • (1987) Free Rad. Biol. Med. , vol.3 , pp. 3-7
    • Raes, M.1    Michiels, C.2    Remacle, J.3
  • 13
    • 0023942502 scopus 로고
    • Significance of alterations in hepatic antioxidant enzymes. Primacy of glutathione peroxidase
    • W. Simmons and I.S. Jamall, Significance of alterations in hepatic antioxidant enzymes. Primacy of glutathione peroxidase, Biochem. J., 251 (1988) 913-917.
    • (1988) Biochem. J. , vol.251 , pp. 913-917
    • Simmons, W.1    Jamall, I.S.2
  • 14
    • 0026751187 scopus 로고
    • The regulation of glutathione peroxidase gene expression by oxygen tension in cultured human cardiomyocytes
    • D.B. Cowan, R.D. Weisel, W.G. Williams and D.A.G. Mickle, The regulation of glutathione peroxidase gene expression by oxygen tension in cultured human cardiomyocytes, J. Mol. Cell Cardiol., 24 (1992) 423-433.
    • (1992) J. Mol. Cell Cardiol. , vol.24 , pp. 423-433
    • Cowan, D.B.1    Weisel, R.D.2    Williams, W.G.3    Mickle, D.A.G.4
  • 15
    • 0027771175 scopus 로고
    • Identification of oxygen responsive elements in the 5́-flanking region of the human glutathione peroxidase gene
    • D.B. Cowan, R.D. Weisel, W.G. Williams and D.A.G. Mickle, Identification of oxygen responsive elements in the 5́-flanking region of the human glutathione peroxidase gene, J. Biol. Chem., 268 (1993) 26904-26910.
    • (1993) J. Biol. Chem. , vol.268 , pp. 26904-26910
    • Cowan, D.B.1    Weisel, R.D.2    Williams, W.G.3    Mickle, D.A.G.4
  • 16
    • 0027476515 scopus 로고
    • Molecular adaptation of vascular endothelial cells to oxidative stress
    • D. Lu, N. Maulik, I.I. Moraru, D.L. Kreutzer and D.K. Das, Molecular adaptation of vascular endothelial cells to oxidative stress, Am. J. Physiol., 264 (1993) C715-C722.
    • (1993) Am. J. Physiol. , vol.264
    • Lu, D.1    Maulik, N.2    Moraru, I.I.3    Kreutzer, D.L.4    Das, D.K.5
  • 17
    • 0020363494 scopus 로고
    • Decrease of superoxide dismutase and glutathione peroxidase in liver of rats treated with hypolipidemic drugs
    • M.R. Ciriolo, I. Mavelli, G. Rotilio, V. Borzatta, M. Cristofari and L. Stanzani, Decrease of superoxide dismutase and glutathione peroxidase in liver of rats treated with hypolipidemic drugs, FEBS Lett., 144 (1982) 264-268.
    • (1982) FEBS Lett. , vol.144 , pp. 264-268
    • Ciriolo, M.R.1    Mavelli, I.2    Rotilio, G.3    Borzatta, V.4    Cristofari, M.5    Stanzani, L.6
  • 18
    • 0022402091 scopus 로고
    • Effects of the hepatocarcinogen nafenopin, a peroxisome proliferator, on the activities of rat liver glutathionerequiring enzymes and catalase in comparison to the action of phenobarbital
    • K. Furukawa, S. Numoto, K. Furuya, N.T. Furukawa and G.M. Williams, Effects of the hepatocarcinogen nafenopin, a peroxisome proliferator, on the activities of rat liver glutathionerequiring enzymes and catalase in comparison to the action of phenobarbital, Cancer Res., 45 (1985) 5011-5019.
    • (1985) Cancer Res. , vol.45 , pp. 5011-5019
    • Furukawa, K.1    Numoto, S.2    Furuya, K.3    Furukawa, N.T.4    Williams, G.M.5
  • 19
    • 0022549354 scopus 로고
    • Peroxisome proliferation and lipid peroxidation in rat liver
    • S.K. Goel, N.D. Lalwani and J.K. Reddy, Peroxisome proliferation and lipid peroxidation in rat liver, Cancer Res., 46 (1986) 1324-1330.
    • (1986) Cancer Res. , vol.46 , pp. 1324-1330
    • Goel, S.K.1    Lalwani, N.D.2    Reddy, J.K.3
  • 21
    • 0026757142 scopus 로고
    • Peroxisome proliferation and resistance to hydrogen peroxide in rat hepatocytes: Is development of resistance an adaptation to cytotoxicity?
    • P. Garberg, U. Stenius, K. Nilsson and J. Högberg, Peroxisome proliferation and resistance to hydrogen peroxide in rat hepatocytes: is development of resistance an adaptation to cytotoxicity? Carcinogenesis, 13 (1992) 1751-1758.
    • (1992) Carcinogenesis , vol.13 , pp. 1751-1758
    • Garberg, P.1    Stenius, U.2    Nilsson, K.3    Högberg, J.4
  • 22
    • 0015880169 scopus 로고
    • Glutathione peroxidase is a selenoenzyme
    • L. Flohé, W.A. Gunzler and H.H. Schock, Glutathione peroxidase is a selenoenzyme, FEBS Lett., 32 (1973) 132-134.
    • (1973) FEBS Lett. , vol.32 , pp. 132-134
    • Flohé, L.1    Gunzler, W.A.2    Schock, H.H.3
  • 24
    • 0025971620 scopus 로고
    • Selenium metabolism in isolated hepatocytes: Inhibition of incorporation in proteins by mono(2-ethylhexyl)phthalate, a metabolite of the peroxisome proliferator di(2-ethylhexyl)phthalate
    • P. Garberg and J. Högberg, Selenium metabolism in isolated hepatocytes: inhibition of incorporation in proteins by mono(2-ethylhexyl)phthalate, a metabolite of the peroxisome proliferator di(2-ethylhexyl)phthalate, Carcinogenesis, 12 (1991) 7-12.
    • (1991) Carcinogenesis , vol.12 , pp. 7-12
    • Garberg, P.1    Högberg, J.2
  • 25
    • 0026517441 scopus 로고
    • Studies on Se incorporation in selenoproteins; effects of peroxisome proliferators and hydrogen peroxide generating system
    • P. Garberg and J. Högberg, Studies on Se incorporation in selenoproteins; effects of peroxisome proliferators and hydrogen peroxide generating system, Chem.-Biol. Interact., 81 (1992) 291-306.
    • (1992) Chem.-Biol. Interact. , vol.81 , pp. 291-306
    • Garberg, P.1    Högberg, J.2
  • 26
    • 0022730806 scopus 로고
    • The structure of the mouse glutathione peroxidase gene: The selenocysteine in the active site is encoded by the 'termination' codon, TGA
    • I. Chambers, J. Frampton, P. Goldfarb, N. Affara, W. McBain and P.R. Harrison, The structure of the mouse glutathione peroxidase gene: the selenocysteine in the active site is encoded by the 'termination' codon, TGA, EMBO J., 5 (1986) 1221-1227.
    • (1986) EMBO J. , vol.5 , pp. 1221-1227
    • Chambers, I.1    Frampton, J.2    Goldfarb, P.3    Affara, N.4    McBain, W.5    Harrison, P.R.6
  • 27
    • 0021099227 scopus 로고
    • The nucleotide sequence of rat liver fatty acid binding protein mRNA
    • J.I. Gordon, D.H. Alpers, R.K. Ockner and A.W. Strauss, The nucleotide sequence of rat liver fatty acid binding protein mRNA, J. Biol. Chem., 258 (1983) 3356-3363.
    • (1983) J. Biol. Chem. , vol.258 , pp. 3356-3363
    • Gordon, J.I.1    Alpers, D.H.2    Ockner, R.K.3    Strauss, A.W.4
  • 28
    • 0024374909 scopus 로고
    • A 14-kilodalton selenium-binding protein in mouse liver is fatty acid-binding protein
    • M.P. Bansal, R.G. Cook, K.G. Danielson and D. Medina, A 14-kilodalton selenium-binding protein in mouse liver is fatty acid-binding protein, J. Biol. Chem., 264 (1989) 13780-13784.
    • (1989) J. Biol. Chem. , vol.264 , pp. 13780-13784
    • Bansal, M.P.1    Cook, R.G.2    Danielson, K.G.3    Medina, D.4
  • 29
    • 0002435288 scopus 로고
    • Notes and comments on the determination of selenium in biological materials
    • V. Galgan and A. Frank, Notes and comments on the determination of selenium in biological materials, Norw. J. Agric. Sci., (Suppl. 11) (1993) 57-74.
    • (1993) Norw. J. Agric. Sci. , Issue.SUPPL. 11 , pp. 57-74
    • Galgan, V.1    Frank, A.2
  • 31
    • 0021288821 scopus 로고
    • Assays of glutathione peroxidase
    • L. Packer (Ed.), Academic Press
    • L. Flohé and W.A. Günzler, Assays of glutathione peroxidase, in: L. Packer (Ed.), Methods in Enzymology, Academic Press, 1984, pp. 114-121.
    • (1984) Methods in Enzymology , pp. 114-121
    • Flohé, L.1    Günzler, W.A.2
  • 32
    • 0025183865 scopus 로고
    • Phospholipid hydroperoxide glutathione peroxidase in various mouse organs during selenium deficiency and repletion
    • F. Weitzel, F. Ursini and A. Wendel, Phospholipid hydroperoxide glutathione peroxidase in various mouse organs during selenium deficiency and repletion, Biochem. Biophys. Acta., 1036 (1990) 88-94.
    • (1990) Biochem. Biophys. Acta. , vol.1036 , pp. 88-94
    • Weitzel, F.1    Ursini, F.2    Wendel, A.3
  • 33
    • 0021803196 scopus 로고
    • The selenoenzyme phospholipid hydroperoxide glutathione peroxidase
    • F. Ursini, M. Maiorino and C. Gregolin, The selenoenzyme phospholipid hydroperoxide glutathione peroxidase, Biochem. Biophys. Acta., 839 (1985) 62-70.
    • (1985) Biochem. Biophys. Acta. , vol.839 , pp. 62-70
    • Ursini, F.1    Maiorino, M.2    Gregolin, C.3
  • 34
    • 0021889599 scopus 로고
    • Identification of the proximate peroxisome proliferator(s) derived from di(2-ethylhexyl)phthalate
    • A.M. Mitchell, J.-C. Lhuguenot, J.W. Bridges and C.R. Elcombe, Identification of the proximate peroxisome proliferator(s) derived from di(2-ethylhexyl)phthalate, Toxicol. Appl. Pharmacol., 80 (1985) 23-32.
    • (1985) Toxicol. Appl. Pharmacol. , vol.80 , pp. 23-32
    • Mitchell, A.M.1    Lhuguenot, J.-C.2    Bridges, J.W.3    Elcombe, C.R.4
  • 35
    • 0017613512 scopus 로고
    • A simplification of the protein assay method of Lowry et al. which is more generally applicable
    • G.L. Peterson, A simplification of the protein assay method of Lowry et al. which is more generally applicable, Anal. Biochem., 83 (1977) 346-356.
    • (1977) Anal. Biochem. , vol.83 , pp. 346-356
    • Peterson, G.L.1
  • 36
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidimum thiocyanate-phenol-chloroform extraction
    • P. Chomczynski and N. Sacchi, Single-step method of RNA isolation by acid guanidimum thiocyanate-phenol-chloroform extraction, Anal. Biochem., 162 (1987) 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 38
    • 0025297918 scopus 로고
    • Molecular biology of selenoproteins
    • R.A. Sunde, Molecular biology of selenoproteins, Annu. Rev. Nutr., 10 (1990) 451-474.
    • (1990) Annu. Rev. Nutr. , vol.10 , pp. 451-474
    • Sunde, R.A.1
  • 39
    • 0028138963 scopus 로고
    • Selenoprotein P. A selenium-rich extracellular glycoprotein
    • R.F. Burk and K.E. Hill, Selenoprotein P. A selenium-rich extracellular glycoprotein, J. Nutr., 124 (1994) 1891-1897.
    • (1994) J. Nutr. , vol.124 , pp. 1891-1897
    • Burk, R.F.1    Hill, K.E.2
  • 40
    • 0027288249 scopus 로고
    • Different patterns of regulation of the genes encoding the closely related 56 kDa selenium-and acetaminophen-binding proteins in normal tissues and during carcinogenesis
    • J. Lanfear, J. Fleming, M. Walker and P. Harrison, Different patterns of regulation of the genes encoding the closely related 56 kDa selenium-and acetaminophen-binding proteins in normal tissues and during carcinogenesis, Carcinogenesis, 14 (1993) 335-340.
    • (1993) Carcinogenesis , vol.14 , pp. 335-340
    • Lanfear, J.1    Fleming, J.2    Walker, M.3    Harrison, P.4
  • 41
    • 0027370773 scopus 로고
    • Significance of selenium-labelled proteins for selenium's chemopreventive functions
    • R. Sinha, M. Bansal, H. Ganther and D. Medina, Significance of selenium-labelled proteins for selenium's chemopreventive functions, Carcinogenesis, 14 (1993) 1895-1900.
    • (1993) Carcinogenesis , vol.14 , pp. 1895-1900
    • Sinha, R.1    Bansal, M.2    Ganther, H.3    Medina, D.4
  • 42
    • 0002095121 scopus 로고
    • Physiology and molecular biology of hepatic cytosolic fatty acid binding protein
    • N. Tavoloni and P.D. Berk (Eds.), Raven Press Ltd., New York
    • N.M. Bass, R.M. Kaikaus and R.K. Ockner, Physiology and molecular biology of hepatic cytosolic fatty acid binding protein, in: N. Tavoloni and P.D. Berk (Eds.), Hepatic Transport and Bile Secretion: Physiology and Pathophysiology, Raven Press Ltd., New York, 1993, pp. 421-446.
    • (1993) Hepatic Transport and Bile Secretion: Physiology and Pathophysiology , pp. 421-446
    • Bass, N.M.1    Kaikaus, R.M.2    Ockner, R.K.3
  • 43
    • 0026725337 scopus 로고
    • Dietary selenium stabilizes glutathione peroxidase messenger RNA in rat liver
    • M.J. Christensen and K.W. Burgener, Dietary selenium stabilizes glutathione peroxidase messenger RNA in rat liver, J. Nutr., 122 (1992) 1620-1626.
    • (1992) J. Nutr. , vol.122 , pp. 1620-1626
    • Christensen, M.J.1    Burgener, K.W.2
  • 45
    • 0025762973 scopus 로고
    • Molecular biology of selenium with implications for its metabolism
    • R. Burk, Molecular biology of selenium with implications for its metabolism, FASEB J., 5 (1991) 2274-2279.
    • (1991) FASEB J. , vol.5 , pp. 2274-2279
    • Burk, R.1
  • 46
    • 0022972341 scopus 로고
    • The nucleotide sequence of the rat liver fatty acid-binding protein gene
    • D.A. Sweetser, J.B. Lowe and J.I. Gordon, The nucleotide sequence of the rat liver fatty acid-binding protein gene, J. Biol. Chem., 261 (1986) 5553-5561.
    • (1986) J. Biol. Chem. , vol.261 , pp. 5553-5561
    • Sweetser, D.A.1    Lowe, J.B.2    Gordon, J.I.3
  • 47
    • 0025022619 scopus 로고
    • Reddy, Elevation of rat liver mRNA for selenium-dependent glutathione peroxidase by selenium deficiency
    • N. Li, P.S. Reddy, K. Thygaraju, A.P. Reddy, B.L. Hsu, R.W. Scholz, C.-P.D. Tu and C. Channa Reddy, Elevation of rat liver mRNA for selenium-dependent glutathione peroxidase by selenium deficiency, J. Biol Chem., 265 (1990) 108-113.
    • (1990) J. Biol Chem. , vol.265 , pp. 108-113
    • Li, N.1    Reddy, P.S.2    Thygaraju, K.3    Reddy, A.P.4    Hsu, B.L.5    Scholz, R.W.6    Tu, C.-P.D.7    Channa, C.8
  • 48
    • 0025173296 scopus 로고
    • DNA sequencing of a mouse liver protein that binds selenium: Implications for selenium's mechanism of action in cancer prevention
    • M.P. Bansal, T. Mukhopadhyay, J. Scott, R.G. Cook, R. Mukhopadhyay and D. Medina, DNA sequencing of a mouse liver protein that binds selenium: implications for selenium's mechanism of action in cancer prevention, Carcinogenesis, 11 (1990) 2071-2073.
    • (1990) Carcinogenesis , vol.11 , pp. 2071-2073
    • Bansal, M.P.1    Mukhopadhyay, T.2    Scott, J.3    Cook, R.G.4    Mukhopadhyay, R.5    Medina, D.6
  • 49
    • 0021206448 scopus 로고
    • Selenite biotransformation to volatile metabolites in an isolated hepatocyte model system
    • A. Ståhl, I. Anundi and J. Högberg, Selenite biotransformation to volatile metabolites in an isolated hepatocyte model system, Biochem. Pharmacol., 33 (1984) 1111-1117.
    • (1984) Biochem. Pharmacol. , vol.33 , pp. 1111-1117
    • Ståhl, A.1    Anundi, I.2    Högberg, J.3
  • 50
    • 0026969562 scopus 로고
    • Selenium in the treatment of heavy metal poisoning and chemical carcinogenesis
    • P.D. Whanger, Selenium in the treatment of heavy metal poisoning and chemical carcinogenesis, J. Trace Elem. Electr. Health Dis., 6 (1992) 209-221.
    • (1992) J. Trace Elem. Electr. Health Dis. , vol.6 , pp. 209-221
    • Whanger, P.D.1
  • 51
    • 0027983083 scopus 로고
    • Liver fatty acid-binding protein-specific mediator of the mitogenesis induced by two classes of carcinogenic peroxisome proliferators
    • S.H. Khan and S. Sorof, Liver fatty acid-binding protein-specific mediator of the mitogenesis induced by two classes of carcinogenic peroxisome proliferators, Proc. Natl. Acad. Sci. USA, 91 (1994) 848-852.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 848-852
    • Khan, S.H.1    Sorof, S.2
  • 52
    • 0023721878 scopus 로고
    • Intracellular 58-kD selenoprotein levels correlate with inhibition of DNA synthesis in mammary epithelial cells
    • D.G. Morrison, M.K. Dishart and D. Medina, Intracellular 58-kD selenoprotein levels correlate with inhibition of DNA synthesis in mammary epithelial cells, Carcinogenesis, 9 (1988) 1801-1810.
    • (1988) Carcinogenesis , vol.9 , pp. 1801-1810
    • Morrison, D.G.1    Dishart, M.K.2    Medina, D.3


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