Activation via the antigen receptor is impaired in T cells, but not in B cells from patients with common variable immunodeficiency

European Journal of Immunology

Volumn 26, Issue 1, 1996, Pages 231-237

  Fischer, Michael B ^a   Wolf, Hermann M ^a   Hauber, Ilona ^a   Eggenbauer, Heinz ^a   Thon, Vojtech ^a   Sasgary, Maria ^a   Eibl, Martha M ^a,b  

^a UNIVERSITY OF VIENNA   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Common variable immunodeficiency; Inositol phosphates; T cell activation; T cell receptor

Indexed keywords

ALUMINUM FLUORIDE; CD28 ANTIGEN; INOSITOL 1,4,5 TRISPHOSPHATE; INTERLEUKIN 2; LYMPHOCYTE ANTIGEN RECEPTOR; LYMPHOCYTE MEMBRANE IMMUNOGLOBULIN; MONOCLONAL ANTIBODY; PHYTOHEMAGGLUTININ; RECOMBINANT INTERLEUKIN 2; STAPHYLOCOCCUS ENTEROTOXIN; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR; TETANUS TOXOID;

ARTICLE; B LYMPHOCYTE ACTIVATION; CLINICAL ARTICLE; COMMON VARIABLE IMMUNODEFICIENCY; CONTROLLED STUDY; ESCHERICHIA COLI; GENE EXPRESSION; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL; SECOND MESSENGER; T LYMPHOCYTE ACTIVATION;

ANTIBODIES, MONOCLONAL; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; COMMON VARIABLE IMMUNODEFICIENCY; ENTEROTOXINS; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; IMMUNOLOGIC MEMORY; INOSITOL 1,4,5-TRISPHOSPHATE; INOSITOL PHOSPHATES; KINETICS; LYMPHOCYTE ACTIVATION; MONOCYTES; RECEPTORS, ANTIGEN, T-CELL; STAPHYLOCOCCUS AUREUS; SUPERANTIGENS; T-LYMPHOCYTES; TETANUS TOXOID;

EID: 0030033394     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.1830260136     Document Type: Article

References (24)

1. Stagg, A. J., Funauchi, M., Knight, S. C., Webster, A. D. B. and Farrant, J., Clin. Exp. Immunol. 1994. 96: 48.
2. Funauchi, M., Farrant, J., Moreno, C. and Webster, A. D. B., Clin. Exp. Immunol. 1995. 101: 82.
3. Fischer, M. B., Hauber, I., Vogel, E., Wolf, H. M., Mannhalter, J. W. and Eibl, M. M., J. Allergy Clin. Immunol. 1993. 92: 340.
4. Fischer, M. B., Hauber, I., Eggenbauer, H., Thon, V., Vogel, E., Schaffer, E., Lokaj, J., Litzman, J., Wolf, H. M., Mannhalter, J. W. and Eibl, M. M., Blood 1994. 84: 4234.
5. Fischer, M. B., Wolf, H. M., Eggenbauer, H., Thon, V., Vogel, E., Lokaj, J., Litzman, J., Mannhalter, J. W. and Eibl, M. M., Clin. Exp. Immunol. 1994. 95: 209.
6. Weiss, A. and Littman, D. R., Cell 1994. 76: 263.
7. Crabtree, G. R. and Clipstone, N. A., Annu. Rev. Biochem. 1994. 63: 1045.
8. Rudd, C. E., Janssen, O., Cai, Y. C., da Silva, A. J., Raab, M. and Prasad, K. V. S., Immunol. Today 1994. 15: 225.
9. Fräser, J. D., Straus, D. and Weiss, A., Immunol. Today 1993. 14: 357.
10. Harnett, M. and Rigley, K., Immunol. Today 1992. 13: 482.
11. Berridge, M. J., Nature 1993. 361: 315.
12. Report of a WHO Scientific Group, Immunodefic. Rev. 1992. 3: 195.
13. Bøyum, A., Scand. J. Clin. Lab. Invest. 1968. 21 (Suppl. 97): 77.
14. Gerwins, P. and Fredholm, B. B., Proc. Natl. Acad. Sci. USA 1992. 89: 7330.
15. Gajewski, T. F., Qian, D., Fields, P. and Fitch, F. W., Proc. Natl. Acad. Sci. USA 1994. 91: 38.
16. Berridge, M. J. and Irvine, R. F., Nature 1984. 312: 315.
17. Coligan, J. E., Kruisbeek, A. M., Margulies, D. H., Shevach, E. M. and Strober, W. in Current Protocols in Immunology, Greene Publishing Association and Wiley-Interscience, John Wiley and Sons, New York 1992.
18. O'Shea, J. J., Urdahl, K. B., Luong, H. T., Chused, T. M., Samelson, L. E. and Klausner, R. D., J. Immunol. 1987. 139: 3463.
19. Fischer, M. B., Hauber, I., Wolf, H. M., Vogel, E., Mannhalter, J. W. and Eibl, M. M., Br. J. Haemat. 1994. 88: 520.
20. O'Flynn, K., Krensky, A. M., Beverley, P. C. L., Burakoff, S. J. and Linch, D. C., Nature 1985. 313: 686.
21. O'Keefe, S. J., Tamura, J., Kincaid, R. L., Tocci, M. J. and O'Neill, E. A., Nature 1992. 357: 692.
22. Nonoyama, S., Farrington, M., Ishida, H., Howard, M. and Ochs, H. D., J. Clin. Invest. 1993. 92: 1282.
23. Geha, R. S. and Rosen, F. S., N. Engl. J. Med. 1994. 330: 1009.
24. Farrington, M., Grosmaire, L. S., Nonoyama, S., Fischer, S. H., Hollenbaugh, D., Ledbetter, J. A., Noelle, R. J., Aruffo, A. and Ochs, H. D., Proc. Natl. Acad. Sci. USA 1994. 91: 1099.