2-[(2-aminobenzyl)sulfinyl]-1-(2-pyridyl)-1,4,5,6-tetrahydrocyclopent[d] imidazoles as a novel class of gastric H+/K+-ATPase inhibitors

Journal of Medicinal Chemistry

Volumn 39, Issue 2, 1996, Pages 596-604

  Yamada, Masaki ^a   Yura, Takeshi ^a   Morimoto, Masamichi ^a   Harada, Tsunehiro ^a   Yamada, Koichiro ^a   Honma, Yasushi ^a   Kinoshita, Mine ^a   Sugiura, Masaki ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 [(2 AMINOBENZYL)SULFINYL] 1,4,5,6 TETRAHYDRO 1 (3 METHYL 2 PYRIDYL)CYCLOPENT[D]IMIDAZOLE; ADENOSINE TRIPHOSPHATASE INHIBITOR; CYCLOHEXIMIDE; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; OMEPRAZOLE; PENTAGASTRIN; PROTON PUMP INHIBITOR; T 776; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME INHIBITION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MEMBRANE VESICLE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; STOMACH ACID SECRETION; STOMACH MUCOSA; STRUCTURE ACTIVITY RELATION; SUBCUTANEOUS DRUG ADMINISTRATION; SWINE;

ANIMALS; ENZYME INHIBITORS; GASTRIC ACID; GASTRIC MUCOSA; H(+)-K(+)-EXCHANGING ATPASE; IMIDAZOLES; MALE; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030032960     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950610n     Document Type: Article

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