Activation of unusual Mac-1+CD4-CD8- T cells bearing αβ antigen receptor in murine lungs during infection with Mycobacterium bovis BCG: Regulation by interferon-γ

Microbiology and Immunology

Volumn 40, Issue 1, 1996, Pages 45-53

  Teruya, Katsuji ^a   Kawakami, Kazuyoshi ^a   Saito, Atsushi ^a  

^a UNIVERSITY OF THE RYUKYUS   (Japan)

Author keywords

Double negative T cells; IFN ; Lung; Mycobacterium bovis BCG

Indexed keywords

BCG VACCINE; GAMMA INTERFERON;

ARTICLE; HOST RESISTANCE; IMMUNOREGULATION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE MIGRATION; MYCOBACTERIUM BOVIS; NONHUMAN; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD4; ANTIGENS, CD8; INTERFERON TYPE II; LUNG; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBSETS; MACROPHAGE-1 ANTIGEN; MALE; MICE; MICE, INBRED DBA; MYCOBACTERIUM BOVIS; MYCOBACTERIUM INFECTIONS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTES; TUBERCULOSIS, PULMONARY;

EID: 0030032950     PISSN: 03855600     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1348-0421.1996.tb03316.x     Document Type: Article

References (37)

1. Abo, T. 1993. Extrathymic pathways of T-cell differentiation: a primitive and fundamental immune system. Micobiol. Immunol. 37: 247-258.
2. Abo, T., Ohteki, T., Koyamada, N., Yoshikai, Y., Masuda, T., Rikiishi, H., and Kumagai, K. 1991. The appearance of T cells bearing self-reactive T cell receptor in the livers of mice injected with bacteria. J. Exp. Med. 174: 417-424.
3. Abo, T., Kusumi, A., Seki, S., Ohteki, T., Sugiura, K., Masuda, T., Rikiishi, H., Iiai, T., and Kumagai, K. 1992. Activation of extrathymic T cells in the liver and reciprocal inactivation of intrathymic T cells by bacterial stimulation. Cell. Immunol. 142: 125-136.
4. Altmann, D.M., Hogg, N., Trowsdale, J., and Wilkinson, D. 1989. Cotransfection of ICAM-1 and HLA-DR reconstitutes human antigen-presenting cell function in mouse L cells. Nature 338: 512-514.
5. Andreu-Sanchez, J.L., de Alboran, I.M., Marcos, M.A.R., Sanchez-Movilla, A., Martinez-A, C., and Kroemer, G. 1991. Interleukin 2 abrogates the nonresponsive state of T cells expressing a forbidden T cell receptor repertoire and induces autoimmune disease in neonatally thymectomized mice. J. Exp. Med. 173: 1323-1329.
6. + subset. J. Immunol. 145: 1039-1045.
7. Barnaba, V., Watts, C., de Boer, M., Lane, P., and Lanzavecchia, A. 1994. Professional presentation of antigen by activated human T cells. Eur. J. Immunol. 24: 71-75.
8. Davidson, W.F., Dumont, F.J., Bedigian, H.G., Fowlkes, B.J., and Morse, III, H.C. 1986. Phenotypic, functional, and molecular genetic comparisons of the abnormal lymphoid cells of C3H-lpr/lpr and C3H-gld/gld mice. J. Immunol. 136: 4075-4084.
9. - T cells bearing αβ T cell receptor. J. Immunol. 14: 3773-3780.
10. Guy-Grand, D., Malassis-Seris, M., Briottet, C., and Vassalli, P. 1991. Cytotoxic differentiation of mouse gut thymodependent and independent intraepithelial T lymphocytes is induced locally. Correlation between functional assays, presence of perfolin and granzyme transcripts, and cytoplasmic granules. J. Exp. Med. 173: 1549-1552.
11. Hanawa, H., Tsuchida, M., Matsumoto, Y., Watanabe, H., Abo, T., Sekikawa, H., Kodama, M., Zhang, S., Izumi, T., and Shibata, A. 1993. Characterization of T cells infiltrating the heart in rats with experimental autoimmune myocarditis. J. Immunol. 150: 5682-5695.
12. Herbelin, A., Machavoine, F., Vicari, A., Schneider, E., Papiernik, M., Ziltener, H., Penit, C., and Dy, M. 1994. Endogenous granulocyte-macrophage colony-stimulating factor is involved in IL-1- and IL-7-induced murine thymocyte proliferation. J. Immunol. 153: 1973-1981.
13. Ikarashi, Y., Abo, T., Kawai, K., Iiai, T., Watanabe, H., Suzuki, K., Matsumoto, Y., Omata, S., and Fujiwara, M. 1993. Expansion of intermediate T-cell receptor cells in mice with autoimmune-like graft-versus-host disease. Immunology 83: 205-212.
14. Kawaguchi, M., Nanno, M., Umesaki, Y., Matsumoto, S., Okada, Y., Cai, Z., Shimamura, T., Matsuoka, Y., Ohwaki, M., and Ishikawa, H. 1993. Cytolytic activity of intestinal intraepithelial lymphocytes in germ-free mice is strain dependent and determined by T cells expressing γδ T-cell antigen receptors. Proc. Natl. Acad. Sci. U.S.A. 90: 8591-8594.
15. Kawakami, K., Kohno, S., Morikawa, N., Kadota, J., Saito, A., and Hara, K. 1994. Activation of macrophages and expansion of specific T lymphocytes in the lungs of mice intratracheally inoculated with Cryptococcus neoformans. Clin. Exp. Immunol. 96: 230-237.
16. - double-negative T cells bearing αβ antigen receptor from conventional ones with either CD4 or CD8 in murine lung. Immunol. Lett. 46: 143-152.
17. - T cells which are extrathymically differentiated in athymic nude mice. Eur. J. Immunol. 23: 1818-1825.
18. Lanzavecchia, A. 1990. Receptor-mediated antigen uptake and its effect on antigen presentation to class II-restricted T lymphocytes. Annu. Rev. Immunol. 8: 773-793.
19. - Tαβ-cells in the liver is a common feature of autoimmune mice. J. Immunol. 147: 2907-2912.
20. Matsumoto, Y., Emoto, M., Usami, J., Maeda, K., and Yoshikai, Y. 1994. A protective role of extrathymic αβ TcR cells in the liver in primary murine salmonellosis. Immunology 81: 8-14.
21. Ohmori, K., Iiai, T., Watanabe, H., Tanaka, T., Miyasaka, M., and Abo, T. 1993. Activation of extrathymic T cells in the liver of mice bearing syngeneic tumors. Biomed. Res. 14: 65-79.
22. - double-negative lymphocytes in autoimmune MRL-lpr/lpr mice. J. Exp. Med. 172: 7-12.
23. - αβ bone marrow T cells with suppressor activity. J. Immunol. 148: 373-380.
24. Pichler, W.J., and Wyss-Coray, T. 1994. T cells as antigen-presenting cells. Immunol. Today 15: 312-315.
25. Robertson, M.J., and Ritz, J. 1990. Biology and clinical relevance of human natural killer cells. Blood 76: 2421-2438.
26. Rocha, B., Vassalli, P., and Guy-Grand, D. 1992. The extrathymic T-cell development pathway. Immunol. Today 13: 449-454.
27. Roncarolo, M.-G., Bigler, M., Haanen, J.B.A., Yssel, H., Bacchetta, R., de Vries, J.E., and Spits, H. 1991. Natural killer cell clones can efficiently process and present protein antigens. J. Immunol. 147: 781-787.
28. Seki, S., Abo, T., Ohteki, T., Sugiura, K., and Kumagai, K. 1991. Unusual αβ-T cells expanded in autoimmune lpr mice are probably a counterpart of normal T cells in the liver. J. Immunol. 147: 1214-1221.
29. 3. Immunology 75: 619-625.
30. Springer, T.A. 1990. Adhesion receptors of the immune system. Nature 346: 425-434.
31. + cells. J. Immunol. 145: 3209-3215.
32. + thymocytes, variable influence of self-antigens on T cell receptor Vβ usage. J. Immunol. 146: 1134-1141.
33. Trinchieri, G. 1989. Biology of natural killer cells. Adv. Immunol. 47: 187-376.
34. - αβ T cells in the subarachnoid space of rats with experimental autoimmune encephalomyelitis. A possible route by which effector cells invade the lesions. Immunology 81: 420-427.
35. von Boehmer, H. 1992. Thymic selection: a matter of life and death. Immunol. Today 13: 454-458.
36. Yankelevich, B., Knobloch, C., Nowicki, M., and Dennert, G. 1989. A novel cell type responsible for marrow graft rejection in mice, T cells with NK phenotype cause acute rejection of marrow grafts. J. Immunol. 142: 3423-3430.
37. Watanabe, H., Iiai, T., Kimura, M., Ohtsuka, K., Tanaka, T., Miyasaka, M., Tsuchida, M., Hanawa, H., and Abo, T. 1993. Characterization of intermediate TCR cells in the liver of mice with respect to their unique IL-2R expression. Cell. Immunol. 149: 331-342.