Definition of three minimal T helper cell epitopes of rubella virus E1 glycoprotein

Clinical and Experimental Immunology

Volumn 104, Issue 3, 1996, Pages 394-397

  Marttila, J ^a   Ilonen, J ^a   Lehtinen, M ^b   Parkkonen, P ^c   Salmi, A ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^c TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

E1 glycoprotein; Rubella virus; T cell epitopes

Indexed keywords

EPITOPE; SYNTHETIC PEPTIDE; VIRUS GLYCOPROTEIN;

ADULT; ARTICLE; CELL LINE; HELPER CELL; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; NORMAL HUMAN; PRIORITY JOURNAL; RUBELLA VIRUS; T LYMPHOCYTE;

EID: 0030032674     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1996.54762.x     Document Type: Article

References (20)

1. Wolinsky JS. Rubella. In: Fields BN, Knipe DM, eds. Fields Virology, 2nd Edn. New York: Raven Press, 1990: 815-38.
2. Smith CA, Petty RE, Tingle AJ. Rubella virus and arthritis. Rheum Dis Clin N Am 1987; 13:265-74.
3. Green KY, Dorsett PH. Rubella virus antigens: localization of epitopes involved. J Virol 1986; 57:893-8.
4. Waxham MN, Wolinsky JS. Detailed immunologic analysis of the structural polypeptides of rubella virus using monoclonal antibodies. Virology 1983; 143:153-65.
5. Chaye HH, Mauracher CA, Tingle AJ, Gillam S. Cellular and humoral immune responses to rubella virus structural protein-E1, protein-E2, and protein-C. J Clin Microbiol 1992; 30:2323-9.
6. Chicz RM, Urban RG, Gorga JC, Vignali DAA, Lane WS, Strominger JL. Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles. J Exp Med 1993; 178:27-47.
7. Hammer J, Valsasnini P, Tolba K, Bolin D, Higelin J, Takacs B, Sinigaglia F. Promiscuous and allele-specific anchors in HLA-DR-binding peptides. Cell 1993; 74:197-203.
8. Sinigaglia F, Hammer J. Review article: rules for peptide binding to MHC class II molecules. APMIS 1994; 102:241-8.
9. Engelhard V. Structure of peptides associated with class I and class II MHC molecules. Annu Rev Immunol 1994; 12:181-207.
10. Vidgren G, Takkinen K, Kalkkinen N. Kääriäinen L, Petterson RF. Nucleotide sequence of the genes coding for the membrane glycoproteins E1 and E2 of rubella virus. J Gen Virol 1987; 68:2347-57.
11. Reece JC, Geysen HM, Rodda SJ. Mapping the major human T helper epitopes of tetanus toxin. The emerging picture. J Immunol 1993; 151:6175-84.
12. Vandal F, Gaudernack G, Funderud S, Bratlie A, Lea T, Ugelstad J, Thorsby E. HLA class I and II typing using cells positively selected from blood by immunomagnetic isolation - a fast and reliable technique. Tissue Antigens 1986; 28:301-12.
13. Lovett AE, McCarthy M, Wolinsky JS. Mapping cell-mediated immunodominant domains of the rubella virus structural proteins using recombinant proteins and synthetic peptides. J Gen Virol 1993; 74:445-52.
14. Mitchell LA, Decarie D, Tingle AJ, Zrein M, Lacroix M. Identification of immunoreactive regions of rubella virus E1 and E2 envelope proteins by using synthetic peptides. Virus Research 1993; 29:33-57.
15. Ou D, Chong P, Tingle AJ, Gillam S. Mapping T-cell epitopes of rubella virus structural protein-E1, protein-E2, and protein-C recognized by T-cell lines and clones derived from infected and immunized populations. J Med Virol 1993;40:175-83.
16. Ilonen J, Seppänen H, Närvänen A, Korkolainen A, Salmi AA. Recognition of synthetic peptides with sequences of rubella virus E1 polypeptide by antibodies and T lymphocytes. Viral Immunol 1992; 5:221-8.
17. Brett SJ, Blau J, Hughes-Jenkins CM, Rhodes J, Liew FY, Tite JP. Human T-cell recognition of influenza-A nucleoprotein - specificity and genetic restriction of immunodominant T-helper cell epitopes. J Immunol 1991; 147:984-91.
18. Ilonen J. Lymphocyte blast transformation response of seropositive and seronegative subjects to herpes simplex, rubella, mumps and measles virus antigens. Acta Pathol Microbiol Scand 1979; C87:151-7.
19. Ou DW, Mitchell LA, Ho M, Decarie D, Tingle AJ, Nepom GT, Lacroix M, Zrein M. Analysis of overlapping T- and B-cell anti-genic sites on rubella virus E1 envelope protein - influence of HLA-DR4 polymorphism on T-cell clonal recognition. Hum Immunol 1994; 39:177-87.
20. Wucherpfennig KW, Strominger JL. Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein. Cell 1995; 80:695-705.