The effects of external pH on calcium channel currents in bullfrog sympathetic neurons

Biophysical Journal

Volumn 70, Issue 3, 1996, Pages 1326-1334

  Zhou, Wei ^a   Jones, Stephen W ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALCIUM CHANNEL; PROTON;

ANIMAL CELL; ARTICLE; BULLFROG; CALCIUM CONDUCTANCE; CALCIUM CURRENT; CHANNEL GATING; ELECTRIC POTENTIAL; NONHUMAN; PH; SURFACE CHARGE; SYMPATHETIC NERVE CELL;

ANIMALIA; RANA CATESBEIANA;

EID: 0030031907     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(96)79689-3     Document Type: Article

References (31)

1. Austin, C., and S. Wray. 1993. Extracellular pH signals affect rat vascular tone by rapid transduction into intracellular pH changes. J. Physiol. (Lond.). 466:1-8.
2. Bean, B. P. 1989. Neurotransmitter inhibition of neuronal calcium currents by changes in channel voltage dependence. Nature. 340:153-156.
3. Begenisich, T. 1975. Magnitude and location of surface charges in Myxicola giant axon. J. Gen. Physiol. 66:47-65.
4. Begenisich, T., and M. Danko. 1983. Hydrogen ion block of the sodium pore in squid giant axons. J. Gen. Physiol. 82:599-618.
5. + channels of stomatal guard cells. Characteristics of the inward rectifier and its control by pH. J. Gen. Physiol. 99:615-644.
6. Daumas, P., and O. S. Andersen. 1993. Proton block of rat brain sodium channels. Evidence for two proton binding sites and multiple occupancy. J. Gen. Physiol. 101:27-43.
7. Grahame, D. C. 1947. The electrical double layer and the theory of electrocapillarity. Chem. Rev. 41:441-501.
8. Hamill, O. P . A. Marty, E. Neher, B. Sakmann, and F. J. Sigworth. 1981. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch. 391:85-100.
9. Hille, B. 1992. Ionic Channels of Excitable Membranes. Smauer Associates, Sunderland, MA.
10. Hille, B., A. M. Woodhull, and B. I. Shapiro. 1975. Negative surface charge near sodium channels of nerve: divalent ions, monovalent ions, and pH. Phil. Trans. R. Soc. Lond. 6270:301-318.
11. Iijima, T., and S. Hagiwara. 1986. Effects of the external pH on Ca channels: experimental and theoretical considerations using a two-site, two-ion model. Proc. Natl. Acad. Sci. USA. 83.654-658.
12. Irisawa, H., and R. Sato. 1986. Intra- and extracellular actions of protons on the calcium current of isolated guinea pig ventricular cells. Circ. Res. 59:348-355.
13. Jones, S. W. 1991. Time course of receptor-channel coupling in frog sympathetic neurons. Biophys. J. 60:502-507.
14. Jones, S. W., and K. S. Elmslie. 1992. Separation and modulation of calcium currents in bull-frog sympathetic neurons. Can. J. Physiol. Pharmacol. 70:S56-S63.
15. Jones, S. W., and T. N. Marks. 1989. Calcium currents in bullfrog sympathetic neurons. I. Activation kinetics and pharmacology. J. Gen. Physiol. 94:151-167.
16. 2+ channels. J. Gen. Physiol. 103:647-663.
17. Klöckner, U , and G. Isenberg. 1994b. Calcium channel current of vascular smooth muscle cells, extracellular protons modulate gating and single channel conductance. J. Gen. Physiol. 103:665-678.
18. Krafte, D. S., and R. S. Kass. 1988. Hydrogen ion modulation of Ca channel current in cardiac ventricular cells Evidence for multiple mechanisms. J. Gen. Physiol. 91.641-657.
19. Kuffier, S. W., and T. J. Sejnowski. 1983 Peptidergic and muscarinic excitation at amphibian sympathetic synapses. J. Physiol. (Lond.). 341:257-278.
20. 2- near cardiac L-type calcium channels: evidence for independent channel-associated binding sites. Biophys. J. 65:1188-1195.
21. - channel. Biochemistry. 28:8092-8099.
22. Ohmori, H., and M. Yoshii. 1977. Surface potential reflected in both gating and permeation mechanisms of sodium and calcium channels of the tunicate egg cell membrane. J. Physiol. (Lond). 267:429-463.
23. + as permeant ions. J. Gen Physiol. 94:1-21.
24. Prod'hom, B., D. Pietrobon, and P. Hess. 1989. Interactions of protons with single open L-type calcium channels. Location of protonation site and dependence of proton-induced current fluctuations on concentration and species of permeant ion. J. Gen. Physiol. 94:23-42
25. Root, M. J., and R. MacKinnon. 1994. Two identical noninteracting sites in an ion channel revealed by proton transfer. Science. 265:1852-1856.
26. Tytgat, J., B. Nilius, and E. Carmeliet. 1990. Modulation of the T-type cardiac Ca channel by changes in proton concentration. J. Gen. Physiol. 96:973-990.
27. +-induced membrane depolarization. FEBS Lett. 361:145-148.
28. West, G. A., D. C. Leppla, and J. M. Simard. 1992. Effects of external pH on ionic currents in smooth muscle cells from the basilar artery of the guinea pig. Circ. Res. 71:201-209.
29. Wilson, D. L., K. Morimoto, Y. Tsuda, and A. M Brown. 1983. Interaction between calcium ions and surface charge as it relates 10 calcium currents. J. Membr. Biol. 72.117-130.
30. Yatani, A., A. M. Brown, and A Akaike. 1984. Effect of extracellular pH on sodium current in isolated single rat ventricular cells. J. Membr Biol. 78:163-168.
31. Zhou, W., and S. W. Jones 1995. Surface charge and calcium channel saturation in bullfrog sympathetic neurons. J. Gen. Physiol. 105: 441-462.