p-Nitrobenzyloxymethyl: A new fluoride-removable protecting group for ribonucleoside 2'-hydroxyls

Tetrahedron Letters

Volumn 37, Issue 7, 1996, Pages 981-982

  Gough, G R ^a   Miller, T J ^a   Mantick, N A ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RIBONUCLEOSIDE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS; RNA SYNTHESIS; TECHNIQUE;

EID: 0030031812     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(95)02357-7     Document Type: Article

References (18)

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6. 7
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8. 5 it is readily cleaved from completed oligomers by irradiation with long-wave UV light. While, as noted above, it is also labile to fluoride ion, its slower rate of removal relative to the para isomer makes fluoride ion deblocking of o-nitrobenzyloxymethyl-protected oligomers inefficient.
9. 13C NMR, and elemental analysis.
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11. 18
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