Chronic pentobarbital administration alters γ-aminobutyric acidA receptor α6-subunit mRNA levels and diazepam-insensitive [3H]Ro15-4513 binding

Synapse

Volumn 22, Issue 2, 1996, Pages 106-113

  Ito, Takehiko ^a   Suzuki, Toshihito ^a,b   Wellman, Susan E ^a   Ho, Ing K ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Barbiturates; Benzodiazepine receptors; Dependence; Inverse agonist; Tolerance

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; 8 AZIDO 5,6 DIHYDRO 5 METHYL 6 OXO 4H IMIDAZO[1,5 A][1,4]BENZODIAZEPINE 3 CARBOXYLIC ACID ETHYL ESTER; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE RECEPTOR; DIAZEPAM; MESSENGER RNA; PENTOBARBITAL; RADIOLIGAND; RECEPTOR SUBUNIT; TRITIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRAIN TISSUE; CONTROLLED STUDY; DRUG DEPENDENCE; DRUG RECEPTOR BINDING; DRUG TOLERANCE; GENE EXPRESSION; GENE INDUCTION; HISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; OSMOTIC MINIPUMP; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; TISSUE SECTION;

ANIMALS; AUTORADIOGRAPHY; AZIDES; BENZODIAZEPINES; BINDING, COMPETITIVE; DIAZEPAM; IN SITU HYBRIDIZATION; MALE; PENTOBARBITAL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; RNA, MESSENGER;

EID: 0030031789     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2396(199602)22:2<106::AID-SYN3>3.0.CO;2-H     Document Type: Article

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