Elevated cerebrospinal fluid sulfatide concentrations as a sign of increased metabolic turnover of myelin in HIV type I infection

AIDS Research and Human Retroviruses

Volumn 12, Issue 2, 1996, Pages 149-155

  Gisslén, Magnus ^a,b   Fredman, Pam ^a   Norkrans, Gunnar ^a   Hagberg, Lars ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; IMMUNOGLOBULIN; MYELIN; SULFATIDE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ARTICLE; BLOOD BRAIN BARRIER; CENTRAL NERVOUS SYSTEM INFECTION; CEREBROSPINAL FLUID LEVEL; CONTROLLED STUDY; DEMENTIA; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; LYMPHOMA; MAJOR CLINICAL STUDY; MALE; OPPORTUNISTIC INFECTION; PRIORITY JOURNAL; PROTEIN METABOLISM; THIN LAYER CHROMATOGRAPHY; TURNOVER TIME;

EID: 0030031570     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.1996.12.149     Document Type: Article

References (39)

1. Ho DD, Rota TR, Schooley RT, Kaplan JC, Allan JD, Groopman JE, et al.: Isolation of HTLV-III from cerebrospinal fluid and neural tissues of patients with neurologic syndromes related to the acquired immunodeficiency syndrome. N Engl J Med 1985; 313:1493-1497.
2. Chiodi F, Sönnerborg A, Albert J, Gaines H, Norkrans G, Hagberg L, et al.: Virus isolation and detection of HIV specific antibodies in cerebrospinal fluid of patients with varying clinical conditions. J Neurol Sci 1988;85:245-257.
3. Chiodi F, Keys B, Albert J, Hagberg L, Lundeberg J, Uhlén M, et al.: HIV-1 is present in the cerebrospinal fluid of a majority of infected individuals. J Clin Microbiol 1992;30:1768-1771.
4. Karlsen N, Reinvang I, and Fröland S: Slowed reaction time in asymptomatic HIV-positive patients. Acta Neurol Scand 1992;86:242-246.
5. Dunlop O, Björklund R, Abdelnoor M, and Myrvang B: Total reaction time: A new approach in early HIV encephalopathy? Acta Neurol Scand 1993;88:344-348.
6. Navia B, Jordan B, and Price R: The AIDS dementia complex: I Clinical features. Ann Neurol 1986;19:517-524.
7. Price RW and Brew BJ: The AIDS dementia complex. J Infect Dis 1988;158:1079-1083.
8. Navia B, Cho E-S, Petito C, and Price R: The AIDS dementia complex: II Neuropathology. Ann Neurol 1986;19:525-535.
9. Power C, Kong P-A, Crawford T, Wesselingh S, Glass J, McArthur J, et al.: Cerebral white matter changes in acquired immunodeficiency syndrome dementia: Alteration of the blood-brain barrier. Ann Neurol 1993;34:339-350.
10. Norton WT and Autilio LA: The lipid composition of purified bovine brain myelin. J Neurochem 1966;13:213-222.
11. Raff MC, Fields KL, Hakomori SI, Mirsky R, Pruss RM, and Winter J: Cell-type-specific markers for distinguishing and studying neurons and the major classes of glia cells in culture. Brain Res 1979;174:283-308.
12. van den Berg L, Sadiq S, Lederman S, and Latov N: The gp120 glycoprotein of HIV-1 binds to sulfatide and to the myelin associated glycoprotein. J Neurosci Res 1992;33:513-518.
13. Furuta Y, Eriksson K, Svennerholm B, Fredman P, Horal P, Jeansson S, et al.: Infection of vaginal and colonic epithelial cells by the human immunodeficiency virus type 1 is neutralized by antibodies raised against conserved epitopes in the envelope glycoprotein gp120. Proc Natl Acad Sci USA 1994; 91:12559-12563.
14. Doljanski F and Kapeller M: Cell surface shedding - The phenomenon and its possible significance. J Theor Biol 1976; 62:253-270.
15. Fredman P, Wallin A, Blennow K, Davidsson P, Gottfries C, and Svennerholm L: Sulfatide as a biochemical marker in cerebrospinal fluid of patients with vascular dementia. Acta Neurol Scand 1992;85:103-106.
16. American Academy of Neurology AIDS Task Force: Nomenclature and research case definitions for neurological manifestations of human immunodeficiency virus-type 1 (HIV-1) infection. Neurology 1991;41:778-785.
17. Davidsson P, Fredman P, Månsson J-E, and Svennerholm L: Determination of gangliosides and sulfatide in human cerebrospinal fluid with microimmunoaffinity technique. Clin Chim Acta 1991;197:105-116.
18. Fredman P, Mattsson L, Andersson K, Davidsson P, Ishizuka I, Jeanssons S, et al.: Characterization of the binding epitope of monoclonal antibody to sulphatide. Biochem J 1988;251:17-22.
19. Laurell C-B: Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies. Anal Biochem 1966; 15:45-52.
20. Tibbling G, Link H, and Öhman S: Principles of albumin and IgG analyses in neurological disorders. I. Establishment of reference values. Scand J Clin Lab Invest 1977;37:385-390.
21. Akrigg A, Wilkinson GWG, and Oram JD: The structure of the major immediate early gene of human cytomegalovirus strain AD169. Virus Res 1985;2:107-121.
22. Studahl M, Ricksten A, Sandberg T, Elowson S, Herner S, Säll C, et al.: Cytomegalovirus infection of the central nervous system in non-compromised patients. Acta Neurol Scand 1994;89:451-457.
23. Wallin A, Gottfries C, Karlsson I, and Svennerholm L: Decreased myelin lipids in Alzheimer's disease and vascular dementia. Acta Neurol Scnad 1989;80:319-323.
24. Rhodes RH: Evidence of serum-protein leakage across the bloodbrain barrier in the acquired immunodeficiency syndrome. J Neuropathol Exp Neurol 1991;50:171-183.
25. McArthur J, Nance-Sproson T, Griffin D, Hoover D, Selnes O, Miller E, et al.: The diagnostic utility of elevation in cerebrospinal fluid β2-microglobulin in HIV-1 dementia. Neurology 1992; 42:1707-1712.
26. Blennow K, Fredman P, Wallin A, Gottfries C-G, Karlsson I, Långström G, et al.: Protein analysis in cerebrospinal fluid. II. Reference values derived from healthy individuals 18-88 years of age. Eur Neurol 1993;33:129-133.
27. Liuzzi GM, Mastroianni CM, Vullo V, Jirillo E, Delia S, and Riccio P: Cerebrospinal fluid myelin basic protein as predictive marker of demyelination in AIDS dementia complex. J Neuroimmunol 1992;36:251-254.
28. Marshall D, Brey R, and Butzin C: Lack of cerebrospinal fluid myelin basic protein in HIV-infected individuals with intrathecal synthesis of IgG. Neurology 1989;39:1127-1129.
29. Pfister HW, Einhäupl KM, Wick M, Fateh-Moghadam A, Huber M, Schielke E, et al.: Myelin basic protein in cerebrospinal fluid of patients infected with HIV. J Neurol 1989;236:288-291.
30. Karlsson B and Alling C: Molecular size of myelin basic protein immunoactivity in spinal fluid. J Neuroimmunol 1984;6:141-150.
31. Wiley C and Nelson J: Role of human immunodeficiency virus and cytomegalovirus in AIDS encephalitis. Am J Pathol 1988; 133:73-81.
32. Wolf D and Spector S: Diagnosis of human cytomegalovirus central nervous system disease in AIDS patients by DNA amplification from cerebrospinal fluid. J Infect Dis 1992;166:1412-1415.
33. Cinque P, Vago L, Brytting M, Castagna A, Accordini A, Sundqvist V-A, et al.: Cytomegalovirus infection of the central nervous system in patients with AIDS: Diagnosis by DNA amplification from cerebrospinal fluid. J Infect Dis 1992;166:1408-1411.
34. Gozlan J, Salord J-M, Roullet E, Baudrimont M, Caburet F, Picard O, et al.: Rapid detection of cytomegalovirus DNA in cerebrospinal fluid of AIDS patients with neurologic disorders. J Infect Dis 1992;166:1416-1421.
35. Hagberg L, Forsman G, Norkrans G, Rybo E, and Svennerholm L: Cytological and immunoglobulin findings in cerebrospinal fluid of symptomatic and asymptomatic human immunodeficiency virus seropositive patients. Infection 1988;16:13-18.
36. Fuchs D, Chiodi F, Albert J, Åsjö B, Hagberg L, Hausen A, et al.: Neopterin concentrations in cerebrospinal fluid and serum of individuals infected with HIV-1. AIDS 1989;3:285-288.
37. Gisslén M, Chiodi F, Fuchs D, Norkrans G, Svennerholm B, Wachter H, et al.: Markers of immune stimulation in the cerebrospinal fluid during HIV infection: A longitudinal study. Scand J Infect Dis 1994;26:523-533.
38. Paz RDL and Enzmann D: Neuroradiology of acquired immunodeficiency syndrome. In: AIDS and the Nervous System. Rosenblum ML (Ed). Raven Press, New York, 1988, pp. 121-153.
39. Monte de la SM, Ho DD, Schooley RT, Hirsch MS, and Richardson EP: Subacute encephalomyelitis of AIDS and its relation to HTLV-III infection. Neurology 1987;37:562-569.