-
1
-
-
84981904448
-
Water soluble polymers in medicine
-
Bader, H., Ringsdorf, H. and Schmidt, B. (1984) Water soluble polymers in medicine. Angew. Makromol. Chem. 123/124, 457-485.
-
(1984)
Angew. Makromol. Chem.
, vol.123-124
, pp. 457-485
-
-
Bader, H.1
Ringsdorf, H.2
Schmidt, B.3
-
2
-
-
0016622773
-
Structure and properties of pharmacologically active polymers
-
Ringsdorf, H. (1975) Structure and properties of pharmacologically active polymers. J. Polym. Sci. Polym. Symp. 51, 135-153.
-
(1975)
J. Polym. Sci. Polym. Symp.
, vol.51
, pp. 135-153
-
-
Ringsdorf, H.1
-
3
-
-
0016260069
-
Lysosomotropic agents
-
De Duve, C., De Barsy, T., Poole, B., Trouet, A., Tulkens, P. and Van Hoof. (1974) Lysosomotropic agents. Biochem. Pharmacol. 23, 2495-2531.
-
(1974)
Biochem. Pharmacol.
, vol.23
, pp. 2495-2531
-
-
De Duve, C.1
De Barsy, T.2
Poole, B.3
Trouet, A.4
Tulkens, P.5
Hoof, V.6
-
4
-
-
0021633364
-
Macromolecular-drug conjugates in targeted cancer chemotherapy
-
Sezaki, H. and Hashida, M.(1983) Macromolecular-drug conjugates in targeted cancer chemotherapy. CRC Crit. Rev. Ther. Drug Carrier Syst. 1, 1-38.
-
(1983)
CRC Crit. Rev. Ther. Drug Carrier Syst.
, vol.1
, pp. 1-38
-
-
Sezaki, H.1
Hashida, M.2
-
5
-
-
0024603948
-
Dextran prodrugs - Structure and stability in relation to therapeutic activity
-
Larsen, C. (1989) Dextran prodrugs - structure and stability in relation to therapeutic activity. Adv. Drug Deliv. Rev. 3, 103-154.
-
(1989)
Adv. Drug Deliv. Rev.
, vol.3
, pp. 103-154
-
-
Larsen, C.1
-
6
-
-
0021271357
-
Tyrosinamide residues enhance pinocytic capture of N-(2-hydroxypropyl)methacrylamide copolymers
-
Duncan, R., Cable, H.C., Rejmanova, P., Kopecek, J. and Lloyd, J.B. (1984) Tyrosinamide residues enhance pinocytic capture of N-(2-hydroxypropyl)methacrylamide copolymers. Biochim. Biophys. Acta 799, 1-8.
-
(1984)
Biochim. Biophys. Acta
, vol.799
, pp. 1-8
-
-
Duncan, R.1
Cable, H.C.2
Rejmanova, P.3
Kopecek, J.4
Lloyd, J.B.5
-
7
-
-
0020682412
-
Targeting of N-(2-hydroxypropyl)methacrylamide copolymers to liver by incorporation of galactose residues
-
Duncan, R., Kopecek, J., Rejmanova, P. and Lloyd, J.B. (1983) Targeting of N-(2-hydroxypropyl)methacrylamide copolymers to liver by incorporation of galactose residues. Biochim. Biophys. Acta 755, 518-521.
-
(1983)
Biochim. Biophys. Acta
, vol.755
, pp. 518-521
-
-
Duncan, R.1
Kopecek, J.2
Rejmanova, P.3
Lloyd, J.B.4
-
8
-
-
0022227637
-
Disulfide spacer between methotrexate and poly(D-lysine)
-
Shen, W.-C., Ryser, H.J.P. and LaManna, L. (1985) Disulfide spacer between methotrexate and poly(D-lysine). J. Biol. Chem. 260, 10905-10908.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 10905-10908
-
-
Shen, W.-C.1
Ryser, H.J.P.2
LaManna, L.3
-
9
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS
-
Matsumura, Y. and Maeda, H. (1986) A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS. Cancer Res. 46, 6387-6392.
-
(1986)
Cancer Res.
, vol.46
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.2
-
10
-
-
0342954344
-
The uptake of labeled proteins by particulate fractions of tumor and normal tissue after injection into mice
-
Mego, J.L. and McQueen, J.D. (1965) The uptake of labeled proteins by particulate fractions of tumor and normal tissue after injection into mice. Cancer Res. 25, 865-869.
-
(1965)
Cancer Res.
, vol.25
, pp. 865-869
-
-
Mego, J.L.1
McQueen, J.D.2
-
11
-
-
0026694788
-
Passive tumour targeting of soluble macromolecules and drug conjugates
-
Seymour, L.W. (1992) Passive tumour targeting of soluble macromolecules and drug conjugates. CRC Crit. Rev. Ther. Drug Carrier Syst. 9, 135-187.
-
(1992)
CRC Crit. Rev. Ther. Drug Carrier Syst.
, vol.9
, pp. 135-187
-
-
Seymour, L.W.1
-
12
-
-
0024839642
-
Tumoritropic and lymphotropic principles of macromolecular drugs
-
Maeda, H. and Matsumura, Y. (1989) Tumoritropic and lymphotropic principles of macromolecular drugs. CRC Crit. Rev. Ther. Drug Carrier Syst. 6, 193-210.
-
(1989)
CRC Crit. Rev. Ther. Drug Carrier Syst.
, vol.6
, pp. 193-210
-
-
Maeda, H.1
Matsumura, Y.2
-
13
-
-
0025333681
-
Microvascular permeability to macromolecules and its dynamic modulation
-
Joyner, W.L. and Kern, D.F. (1990) Microvascular permeability to macromolecules and its dynamic modulation. Adv. Drug Deliv. Rev. 4, 319-342.
-
(1990)
Adv. Drug Deliv. Rev.
, vol.4
, pp. 319-342
-
-
Joyner, W.L.1
Kern, D.F.2
-
14
-
-
0023157363
-
Angiogenic factors
-
Folkman, J. and Klagsbrun, M. (1987) Angiogenic factors. Science 235, 442-447.
-
(1987)
Science
, vol.235
, pp. 442-447
-
-
Folkman, J.1
Klagsbrun, M.2
-
15
-
-
0021111648
-
Tumour cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
-
Senger, D.R., Galli, S.S., Dvorak, A.M., Perruzzi, C.A., Harvey, V.S. and Dvorak, H.F. (1983) Tumour cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 219, 983-985.
-
(1983)
Science
, vol.219
, pp. 983-985
-
-
Senger, D.R.1
Galli, S.S.2
Dvorak, A.M.3
Perruzzi, C.A.4
Harvey, V.S.5
Dvorak, H.F.6
-
16
-
-
0026926609
-
Conjugates of anticancer agents and polymers: Advantages of macromolecular therapeutics in vivo
-
Maeda, H., Seymour, L.W. and Miyamoto, Y. (1992) Conjugates of anticancer agents and polymers: advantages of macromolecular therapeutics in vivo. Bioconj. Chem. 3, 351-362.
-
(1992)
Bioconj. Chem.
, vol.3
, pp. 351-362
-
-
Maeda, H.1
Seymour, L.W.2
Miyamoto, Y.3
-
17
-
-
0021912846
-
Regulation of extracellular coagulation by microvascular permeability
-
Dvorak, H.F., Senger, D.R, Dvorak, A.M., Harvey, V.S. and McDonagh, J. (1985) Regulation of extracellular coagulation by microvascular permeability. Science 227, 1059-1061.
-
(1985)
Science
, vol.227
, pp. 1059-1061
-
-
Dvorak, H.F.1
Senger, D.R.2
Dvorak, A.M.3
Harvey, V.S.4
McDonagh, J.5
-
18
-
-
0026118760
-
SMANCS and polymer-conjugated macromolecular drugs: Advantages in cancer chemotherapy
-
Maeda, H. (1991) SMANCS and polymer-conjugated macromolecular drugs: advantages in cancer chemotherapy. Adv. Drug Deliv. Rev. 6, 181-202.
-
(1991)
Adv. Drug Deliv. Rev.
, vol.6
, pp. 181-202
-
-
Maeda, H.1
-
19
-
-
0023219734
-
Transport of macromolecules in the tumour interstitium: A review
-
Jain, R.K. (1987) Transport of macromolecules in the tumour interstitium: a review. Cancer Res. 47, 3039-3051.
-
(1987)
Cancer Res.
, vol.47
, pp. 3039-3051
-
-
Jain, R.K.1
-
20
-
-
84985534843
-
Explorations in cell biology and pharmacology using synthetic polymers
-
Lloyd, J.B. (1989) Explorations in cell biology and pharmacology using synthetic polymers. Angew. Makromol. Chem. 166/167, 191-200.
-
(1989)
Angew. Makromol. Chem.
, vol.166-167
, pp. 191-200
-
-
Lloyd, J.B.1
-
21
-
-
0022459165
-
Pinocytosis and phagocytosis: The effect of size of a particulate substrate on its mode of capture by rat peritoneal macrophages cultured in vitro
-
Pratten, M.K. and Lloyd, J.B. (1986) Pinocytosis and phagocytosis: the effect of size of a particulate substrate on its mode of capture by rat peritoneal macrophages cultured in vitro. Biochim. Biophys. Acta 881, 307-313.
-
(1986)
Biochim. Biophys. Acta
, vol.881
, pp. 307-313
-
-
Pratten, M.K.1
Lloyd, J.B.2
-
22
-
-
0020692625
-
Endocytosis: A review of mechanisms and plasma membrane dynamics
-
Besterman, J.M. and Low, R.B. (1983) Endocytosis: a review of mechanisms and plasma membrane dynamics. Biochem. J. 210, 1-13.
-
(1983)
Biochem. J.
, vol.210
, pp. 1-13
-
-
Besterman, J.M.1
Low, R.B.2
-
24
-
-
0019884074
-
Pinocytic uptake and intracellular degradation of N-(2-hydroxypropyl)methacrylamide copolymers. A potential drug delivery system
-
Duncan, R., Rejmanova, P., Kopecek, J. and Lloyd, J.B.(1981) Pinocytic uptake and intracellular degradation of N-(2-hydroxypropyl)methacrylamide copolymers. A potential drug delivery system. Biochim. Biophys. Acta 678, 143-150.
-
(1981)
Biochim. Biophys. Acta
, vol.678
, pp. 143-150
-
-
Duncan, R.1
Rejmanova, P.2
Kopecek, J.3
Lloyd, J.B.4
-
25
-
-
0021243293
-
Non-specific adsorptive pinocytosis
-
Lloyd, J.B. and Williams, K.E. (1984) Non-specific adsorptive pinocytosis. Biochem. Soc. Trans. 12, 527-528.
-
(1984)
Biochem. Soc. Trans.
, vol.12
, pp. 527-528
-
-
Lloyd, J.B.1
Williams, K.E.2
-
26
-
-
0024462034
-
Receptor-mediated delivery of drugs to hepatocytes
-
Fallen, R.J. and Schwartz, A.L. (1989) Receptor-mediated delivery of drugs to hepatocytes. Adv. Drug Deliv. Rev. 4, 49-63.
-
(1989)
Adv. Drug Deliv. Rev.
, vol.4
, pp. 49-63
-
-
Fallen, R.J.1
Schwartz, A.L.2
-
27
-
-
0021741535
-
Substrate selection and processing in endocytosis
-
Lloyd, J.B., Pratten, M.K., Duncan, R., Kooistra, T. and Cartlidge, S.A. (1984) Substrate selection and processing in endocytosis. Biochem. Soc. Trans. 12, 977-978.
-
(1984)
Biochem. Soc. Trans.
, vol.12
, pp. 977-978
-
-
Lloyd, J.B.1
Pratten, M.K.2
Duncan, R.3
Kooistra, T.4
Cartlidge, S.A.5
-
28
-
-
0020382603
-
Pinocytosis of polyα,β-(N-2-hydroxyethyl)-DL-aspartamide and tyramine derivatives by rat visceral yolk sacs cultured in vitro
-
1982
-
Duncan, R., Starling, D., Rypacek, F., Drobnik, J. and Lloyd, J.B. (1982) Pinocytosis of poly(α,β-(N-2-hydroxyethyl)-DL-aspartamide and tyramine derivatives by rat visceral yolk sacs cultured in vitro. Biochim. Biophys. Acta, 1982, 717, 248-254.
-
(1982)
Biochim. Biophys. Acta
, vol.717
, pp. 248-254
-
-
Duncan, R.1
Starling, D.2
Rypacek, F.3
Drobnik, J.4
Lloyd, J.B.5
-
29
-
-
0021874101
-
Characterisation of the adsorptive pinocytic capture of a polyaspartamide modified by the incorporation of tyramine residues
-
Duncan, R., Cable, H.C., Rypacek, F., Drobnik, J. and Lloyd, J.B. (1985) Characterisation of the adsorptive pinocytic capture of a polyaspartamide modified by the incorporation of tyramine residues. Biochim. Biophys. Acta 840, 291-293.
-
(1985)
Biochim. Biophys. Acta
, vol.840
, pp. 291-293
-
-
Duncan, R.1
Cable, H.C.2
Rypacek, F.3
Drobnik, J.4
Lloyd, J.B.5
-
30
-
-
0343389771
-
Enhancement of adsorptive pinocytosis of a polyaspartaraide modified by the incorporation of tyramine residues
-
Duncan, R., Cable, H.C., Rypacek, F., Drobnik, J. and Lloyd, J.B. (1984) Enhancement of adsorptive pinocytosis of a polyaspartaraide modified by the incorporation of tyramine residues. Biochem. Soc. Trans. 12, 1064.
-
(1984)
Biochem. Soc. Trans.
, vol.12
, pp. 1064
-
-
Duncan, R.1
Cable, H.C.2
Rypacek, F.3
Drobnik, J.4
Lloyd, J.B.5
-
31
-
-
0001036012
-
Micelle-forming block copolymers: Pinocytosis by macrophages and interaction with model membranes
-
Pratten, M.K., Lloyd, J.B., Hörpel, G. and Ringsdorf, H. (1985) Micelle-forming block copolymers: pinocytosis by macrophages and interaction with model membranes. Makromol. Chem.186, 725-733.
-
(1985)
Makromol. Chem.
, vol.186
, pp. 725-733
-
-
Pratten, M.K.1
Lloyd, J.B.2
Hörpel, G.3
Ringsdorf, H.4
-
32
-
-
0020352106
-
Adsorptive pinocytosis of polycationic copolymers of vinylpyrrolidone with vinylamine by rat yolk sac and rat peritoneal macrophages
-
Pratten, M.K., Cable, H.C., Ringsdorf, H. and Lloyd, J.B. (1982) Adsorptive pinocytosis of polycationic copolymers of vinylpyrrolidone with vinylamine by rat yolk sac and rat peritoneal macrophages. Biochim. Biophys. Acta, 719, 424-430.
-
(1982)
Biochim. Biophys. Acta
, vol.719
, pp. 424-430
-
-
Pratten, M.K.1
Cable, H.C.2
Ringsdorf, H.3
Lloyd, J.B.4
-
33
-
-
0028418574
-
Soluble polymers for lectin-mediated drug targeting
-
Seymour, L.W. (1994) Soluble polymers for lectin-mediated drug targeting. Adv. Drug Deliv. Rev. 14, 89-111.
-
(1994)
Adv. Drug Deliv. Rev.
, vol.14
, pp. 89-111
-
-
Seymour, L.W.1
-
34
-
-
0025780397
-
Fate of glycosylated dextrans after in vivo administration
-
Vansteenkiste, S., Schacht, E., Duncan, R., Seymour, L., Pawluczyk, I. and Baldwin, R. (1991) Fate of glycosylated dextrans after in vivo administration. J. Control. Release 16, 91-100.
-
(1991)
J. Control. Release
, vol.16
, pp. 91-100
-
-
Vansteenkiste, S.1
Schacht, E.2
Duncan, R.3
Seymour, L.4
Pawluczyk, I.5
Baldwin, R.6
-
35
-
-
0025855856
-
Comparison of the liver subcellular distribution of free daunomycin and that bound to galactosamine targeted N-(2-hydroxypropyl)methacrylamide copolymers, following intravenous administration to the rat
-
Wedge, S.R., Duncan, R. and Kopeckova, P.(1991) Comparison of the liver subcellular distribution of free daunomycin and that bound to galactosamine targeted N-(2-hydroxypropyl)methacrylamide copolymers, following intravenous administration to the rat. Br. J. Cancer 63, 546-549.
-
(1991)
Br. J. Cancer
, vol.63
, pp. 546-549
-
-
Wedge, S.R.1
Duncan, R.2
Kopeckova, P.3
-
36
-
-
0023829660
-
Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. II. Evaluation of daunomycin conjugates in vivo against L1210 leukaemia
-
Duncan, R., Kopeckova, P., Strohalm, J., Hume, I.C., Lloyd, J.B. and Kopecek, J. (1988) Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. II. Evaluation of daunomycin conjugates in vivo against L1210 leukaemia. Br. J. Cancer 57, 147-156.
-
(1988)
Br. J. Cancer
, vol.57
, pp. 147-156
-
-
Duncan, R.1
Kopeckova, P.2
Strohalm, J.3
Hume, I.C.4
Lloyd, J.B.5
Kopecek, J.6
-
37
-
-
0028414109
-
Glycoconjugates as carriers for specific delivery of therapeutic drugs and genes
-
Monsigny, M., Roche, A.-C., Midoux, P. and Mayer, R. (1994) Glycoconjugates as carriers for specific delivery of therapeutic drugs and genes. Adv. Drug Deliv. Rev. 14, 1-24.
-
(1994)
Adv. Drug Deliv. Rev.
, vol.14
, pp. 1-24
-
-
Monsigny, M.1
Roche, A.-C.2
Midoux, P.3
Mayer, R.4
-
38
-
-
0023141221
-
Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. I. Evaluation of daunomycin and puromycin conjugates in vitro
-
Duncan, R., Kopeckova-Rejmanova, P., Strohalm, J., Hume, I., Cable, H.C., Pohl, J., Lloyd, J.B. and Kopecek, J. (1987) Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. I. Evaluation of daunomycin and puromycin conjugates in vitro. Br. J. Cancer 55, 165-174.
-
(1987)
Br. J. Cancer
, vol.55
, pp. 165-174
-
-
Duncan, R.1
Kopeckova-Rejmanova, P.2
Strohalm, J.3
Hume, I.4
Cable, H.C.5
Pohl, J.6
Lloyd, J.B.7
Kopecek, J.8
-
39
-
-
0024469053
-
Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. III. Evaluation of adriamycin conjugates against mouse leukaemia L1210 in vivo
-
Duncan, R., Hume, I.C., Kopeckova, P., Ulbrich, K., Strohalm, J. and Kopecek, J. (1989) Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. III. Evaluation of adriamycin conjugates against mouse leukaemia L1210 in vivo. J. Control. Release 10, 51-63.
-
(1989)
J. Control. Release
, vol.10
, pp. 51-63
-
-
Duncan, R.1
Hume, I.C.2
Kopeckova, P.3
Ulbrich, K.4
Strohalm, J.5
Kopecek, J.6
-
40
-
-
0028853112
-
Glucose oxidase as a tool to study in vivo the interaction of glycosylated polymers with the mannose receptors of macrophages
-
Domurado, M., Domurado, D., Vansteenkiste, S., De Marre, A. and Schacht, E. (1995) Glucose oxidase as a tool to study in vivo the interaction of glycosylated polymers with the mannose receptors of macrophages. J. Control. Release 33, 115-123.
-
(1995)
J. Control. Release
, vol.33
, pp. 115-123
-
-
Domurado, M.1
Domurado, D.2
Vansteenkiste, S.3
De Marre, A.4
Schacht, E.5
-
41
-
-
0023625511
-
Potential of sugar residues attached to N-(2-hydroxypropyl)methacrylamide copolymers as targeting groups for the selective delivery of drugs
-
Seymour, L.W., Duncan, R., Kopeckova, P. and Kopecek, J. (1987) Potential of sugar residues attached to N-(2-hydroxypropyl)methacrylamide copolymers as targeting groups for the selective delivery of drugs. J. Bioact. Compatible Polym. 2, 97-119.
-
(1987)
J. Bioact. Compatible Polym.
, vol.2
, pp. 97-119
-
-
Seymour, L.W.1
Duncan, R.2
Kopeckova, P.3
Kopecek, J.4
-
42
-
-
0024439808
-
Evaluation of N-(2-hydroxypropyl)methacrylamide copolymers as targetable drug carriers. 1. Binding, pinocytic uptake and intracellular distribution of transferrin and anti-transferrin receptor antibody conjugates
-
Flanagan, P.A., Kopecekova, P., Kopecek, J. and Duncan, R. (1989) Evaluation of N-(2-hydroxypropyl)methacrylamide copolymers as targetable drug carriers. 1. Binding, pinocytic uptake and intracellular distribution of transferrin and anti-transferrin receptor antibody conjugates. Biochim. Biophys. Acta 993, 83-91.
-
(1989)
Biochim. Biophys. Acta
, vol.993
, pp. 83-91
-
-
Flanagan, P.A.1
Kopecekova, P.2
Kopecek, J.3
Duncan, R.4
-
43
-
-
0001491999
-
Polymeric antitumour agents on a molecular and on a cellular level?
-
Gros, L., Ringsdorf, H. and Schupp, H. (1981) Polymeric antitumour agents on a molecular and on a cellular level? Angew. Chem. Int. Ed. Engl. 20, 305-325.
-
(1981)
Angew. Chem. Int. Ed. Engl.
, vol.20
, pp. 305-325
-
-
Gros, L.1
Ringsdorf, H.2
Schupp, H.3
-
44
-
-
0027987791
-
Polymer conjugates; pharmacokinetic considerations for design and development
-
Duncan, R. and Spreafico, F. (1994) Polymer conjugates; pharmacokinetic considerations for design and development. Clin. Pharmacokinet. 27, 290-306.
-
(1994)
Clin. Pharmacokinet.
, vol.27
, pp. 290-306
-
-
Duncan, R.1
Spreafico, F.2
-
45
-
-
0028416238
-
Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis
-
Wagner, E., Curiel, D. and Gotten, M. (1994) Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis. Adv. Drug. Deliv. Rev. 14, 113-135.
-
(1994)
Adv. Drug. Deliv. Rev.
, vol.14
, pp. 113-135
-
-
Wagner, E.1
Curiel, D.2
Gotten, M.3
-
46
-
-
0024462168
-
125I]daunomycin
-
125I]daunomycin. J. Control. Release 10, 37-49.
-
(1989)
J. Control. Release
, vol.10
, pp. 37-49
-
-
Rihova, B.1
Veres, K.2
Fornusek, L.3
Ulbrich, K.4
Strohalm, J.5
Vetvicka, V.6
Bilej, M.7
Kopecek, J.8
-
47
-
-
0026561594
-
Antibody-targeted cyclosporin A
-
Rihova, B., Jegorov, A., Strohalm, J., Matha, V., Rossmann, P., Fornusek, L. and Ulbrich, K. (1992) Antibody-targeted cyclosporin A. J. Control. Release 19, 25-40.
-
(1992)
J. Control. Release
, vol.19
, pp. 25-40
-
-
Rihova, B.1
Jegorov, A.2
Strohalm, J.3
Matha, V.4
Rossmann, P.5
Fornusek, L.6
Ulbrich, K.7
-
48
-
-
0027253329
-
6 toward human hepatocarcinoma cell line (PLC/PRF/S) targeted with galactosamine and to mouse splenocytes targeted with anti-Thy 1.2 antibodies
-
6 toward human hepatocarcinoma cell line (PLC/PRF/S) targeted with galactosamine and to mouse splenocytes targeted with anti-Thy 1.2 antibodies. J. Control. Release 25, 71-87.
-
(1993)
J. Control. Release
, vol.25
, pp. 71-87
-
-
Rihova, B.1
Krinik, N.L.2
Kopecek, J.3
-
49
-
-
0024318447
-
Action of polymeric prodrugs based on N-(2-hydroxypropyl)methacrylamide copolymers. I. Suppression of the antibody response and proliferation of mouse splenocytes in vitro
-
Rihova, B., Vetvicka, V., Strohalm, J., Ulbrich, K. and Kopecek, J. (1989) Action of polymeric prodrugs based on N-(2-hydroxypropyl)methacrylamide copolymers. I. Suppression of the antibody response and proliferation of mouse splenocytes in vitro. J. Control. Release 9, 21-32.
-
(1989)
J. Control. Release
, vol.9
, pp. 21-32
-
-
Rihova, B.1
Vetvicka, V.2
Strohalm, J.3
Ulbrich, K.4
Kopecek, J.5
-
50
-
-
0025832801
-
Targetable photoactivatable polymeric drugs
-
Kopecek, J., Rihova, B. and Krinik, N.L. (1991) Targetable photoactivatable polymeric drugs. J. Control. Release 16, 137-144.
-
(1991)
J. Control. Release
, vol.16
, pp. 137-144
-
-
Kopecek, J.1
Rihova, B.2
Krinik, N.L.3
-
51
-
-
0026069645
-
Synthetic polymers conjugated to monoclonal antibodies: Vehicles for tumour-targeted drug delivery
-
Seymour, L.W., Flanagan, P.A., Al-Shamkhani, A., Subr, V., Ulbrich, K., Cassidy, J. and Duncan, R. (1991) Synthetic polymers conjugated to monoclonal antibodies: vehicles for tumour-targeted drug delivery. Selective Cancer Ther. 7, 59-73.
-
(1991)
Selective Cancer Ther.
, vol.7
, pp. 59-73
-
-
Seymour, L.W.1
Flanagan, P.A.2
Al-Shamkhani, A.3
Subr, V.4
Ulbrich, K.5
Cassidy, J.6
Duncan, R.7
-
52
-
-
0024448456
-
The intracellular release of methotrexate from a synthetic drug carrier system targetd to Fc receptor-bearing cells
-
Shen, W.-C., Du, X., Feener, E.P. and Ryser, H.J.P. (1989) The intracellular release of methotrexate from a synthetic drug carrier system targetd to Fc receptor-bearing cells. J. Control. Release 10, 89-96.
-
(1989)
J. Control. Release
, vol.10
, pp. 89-96
-
-
Shen, W.-C.1
Du, X.2
Feener, E.P.3
Ryser, H.J.P.4
-
53
-
-
0027130079
-
Polymeric drug carriers containing doxorubicin and melanocyte-stimulating hormone: In vitro and in vivo evaluation against murine melanoma
-
O'Hare, K.B., Duncan, R., Strohalm, J., Ulbrich, K. and Kopeckova, P. (1993) Polymeric drug carriers containing doxorubicin and melanocyte-stimulating hormone: in vitro and in vivo evaluation against murine melanoma. J. Drug Targeting 1, 217-229.
-
(1993)
J. Drug Targeting
, vol.1
, pp. 217-229
-
-
O'Hare, K.B.1
Duncan, R.2
Strohalm, J.3
Ulbrich, K.4
Kopeckova, P.5
-
54
-
-
0027227288
-
Molecular cloning, expression and gene localisation of a fourth melanocortin receptor
-
Gantz, I., Miwa, H., Konda, Y., Shimto, Y., Tashiro, T., Watson, S.J., DelValle, J. and Yamada, T. (1993) Molecular cloning, expression and gene localisation of a fourth melanocortin receptor. J. Biol. Chem. 268, 15174-15179.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 15174-15179
-
-
Gantz, I.1
Miwa, H.2
Konda, Y.3
Shimto, Y.4
Tashiro, T.5
Watson, S.J.6
DelValle, J.7
Yamada, T.8
-
55
-
-
0027436690
-
Identification of a receptor for γ-melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system
-
Roselli-Rehfuss, L., Mountjoy, K.G., Robbins, L.S., Mortrud, M.T., Low, M.J., Tatro, J.B., Entwistle, M.L., Simerley, R.B. and Cone, R.D. (1993) Identification of a receptor for γ-melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system. Proc. Natl. Acad. Sci. USA 90, 8856-8860.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8856-8860
-
-
Roselli-Rehfuss, L.1
Mountjoy, K.G.2
Robbins, L.S.3
Mortrud, M.T.4
Low, M.J.5
Tatro, J.B.6
Entwistle, M.L.7
Simerley, R.B.8
Cone, R.D.9
-
56
-
-
0025354858
-
Evidence for a dipeptide porter in the lysosome membrane
-
Bird, S.J. and Lloyd, J.B. (1990) Evidence for a dipeptide porter in the lysosome membrane. Biochim. Biophys. Acta 1024, 267-270.
-
(1990)
Biochim. Biophys. Acta
, vol.1024
, pp. 267-270
-
-
Bird, S.J.1
Lloyd, J.B.2
-
57
-
-
0000859980
-
Polymers containing enzymatically degradable bonds. 7. Design of oligopeptide side chains in poly[N-(2-hydroxypropyl)methacrylamide] copolymers to promote efficient degradation by lysosomal enzymes
-
Rejmanova, P., Kopecek, J., Pohl, J., Baudys, M. and Kostka, V. (1983) Polymers containing enzymatically degradable bonds. 7. Design of oligopeptide side chains in poly[N-(2-hydroxypropyl)methacrylamide] copolymers to promote efficient degradation by lysosomal enzymes. Makromol. Chem. 184, 2009-2020.
-
(1983)
Makromol. Chem.
, vol.184
, pp. 2009-2020
-
-
Rejmanova, P.1
Kopecek, J.2
Pohl, J.3
Baudys, M.4
Kostka, V.5
-
58
-
-
0019786031
-
Cis-aconityl spacer between daunomycin and macromolecular carriers; a model of pH-sensitive likage releasing drug from a lysosomotropic agent
-
Shen, W.-C. and Ryser, H.J.P. (1981) Cis-aconityl spacer between daunomycin and macromolecular carriers; a model of pH-sensitive likage releasing drug from a lysosomotropic agent. Biochem. Biophys. Res. Commun. 102, 1048-1054.
-
(1981)
Biochem. Biophys. Res. Commun.
, vol.102
, pp. 1048-1054
-
-
Shen, W.-C.1
Ryser, H.J.P.2
-
59
-
-
0023710359
-
p-Benzylthiocarbamoyl-aspartyl-daunorubicin-substituted polytrisacryl. A new drug acid-labile arm-carrier conjugate
-
Daussin, F., Boschetti, E., Delmotte, F. and Monsigny, M. (1988) p-Benzylthiocarbamoyl-aspartyl-daunorubicin-substituted polytrisacryl. A new drug acid-labile arm-carrier conjugate. Eur. J. Biochem. 176, 625-628.
-
(1988)
Eur. J. Biochem.
, vol.176
, pp. 625-628
-
-
Daussin, F.1
Boschetti, E.2
Delmotte, F.3
Monsigny, M.4
-
60
-
-
0025211844
-
Acid-sensitive dissociation between polylysine and histamine modified poly(glutamate) as a model for drug-releasing carriers in endosomes
-
Shen, W.-C. (1990) Acid-sensitive dissociation between polylysine and histamine modified poly(glutamate) as a model for drug-releasing carriers in endosomes. Biochim. Biophys. Acta 1034, 122-124.
-
(1990)
Biochim. Biophys. Acta
, vol.1034
, pp. 122-124
-
-
Shen, W.-C.1
-
61
-
-
0026669605
-
Drug targeting: Synthesis and endocytosis of oligonucleotide-neoglycoprotein conjugates
-
Bonfils, E., Depierreux, C., Midoux, P., Thuong, N.T., Monsigny, M. and Roche, A.C. (1992) Drug targeting: synthesis and endocytosis of oligonucleotide-neoglycoprotein conjugates. Nucleic Acids Res. 20, 4621-4629.
-
(1992)
Nucleic Acids Res.
, vol.20
, pp. 4621-4629
-
-
Bonfils, E.1
Depierreux, C.2
Midoux, P.3
Thuong, N.T.4
Monsigny, M.5
Roche, A.C.6
-
62
-
-
0001288058
-
Polymers containing enzymatically degradable bonds. 4. Preliminary experiments in vivo
-
Kopecek, K., Cifkova, I., Rejmanova, P., Strohalm, J., Obereigner, B. and Ulbrich, K (1981) Polymers containing enzymatically degradable bonds. 4. Preliminary experiments in vivo. Makromol. Chem. 182, 2941-2949.
-
(1981)
Makromol. Chem.
, vol.182
, pp. 2941-2949
-
-
Kopecek, K.1
Cifkova, I.2
Rejmanova, P.3
Strohalm, J.4
Obereigner, B.5
Ulbrich, K.6
-
63
-
-
0001288057
-
Polymers containing enzymatically degradable bonds. 1. Chymotrypsin catalysed hydrolysis of p-nitroanilides of phenylalanine and tyrosine attached to side chains of copolymers of N-(2-hydroxypropyl)methacrylamide
-
Kopecek, K. Rejmanova, P. and Chytry, V (1981) Polymers containing enzymatically degradable bonds. 1. Chymotrypsin catalysed hydrolysis of p-nitroanilides of phenylalanine and tyrosine attached to side chains of copolymers of N-(2-hydroxypropyl)methacrylamide. Makromol. Chem. 182, 799-809.
-
(1981)
Makromol. Chem.
, vol.182
, pp. 799-809
-
-
Kopecek, K.1
Rejmanova, P.2
Chytry, V.3
-
64
-
-
0020467066
-
Degradation of side-chains of N-(2-hydroxypropyl)methacrylamide copolymers by lysosomal thiol-proteinases
-
Duncan, R., Cable, H.C., Lloyd, J.B., Rejmanova, P. and Kopecek, J. (1982) Degradation of side-chains of N-(2-hydroxypropyl)methacrylamide copolymers by lysosomal thiol-proteinases. Biosci. Rep. 2, 1041-1046.
-
(1982)
Biosci. Rep.
, vol.2
, pp. 1041-1046
-
-
Duncan, R.1
Cable, H.C.2
Lloyd, J.B.3
Rejmanova, P.4
Kopecek, J.5
-
65
-
-
0000747685
-
Polymers containing enzymatically degradable bonds. 9. Chymotrypsin catalysed hydrolysis of a p-nitroanilide drug model bound via oligopeptides onto poly(vinylpyrrolidone co maleic anhydride)
-
Pato, J., Azori, M., Ulbrich, K. and Kopecek, J. (1984) Polymers containing enzymatically degradable bonds. 9. Chymotrypsin catalysed hydrolysis of a p-nitroanilide drug model bound via oligopeptides onto poly(vinylpyrrolidone co maleic anhydride). Makromol. Chem. 185, 231-237.
-
(1984)
Makromol. Chem.
, vol.185
, pp. 231-237
-
-
Pato, J.1
Azori, M.2
Ulbrich, K.3
Kopecek, J.4
-
66
-
-
0001161797
-
Poly(ethylene glycol)s containing enzymatically degradable bonds
-
Ulbrich, K., Strohalm, J. and Kopecek, J. (1986) Poly(ethylene glycol)s containing enzymatically degradable bonds. Makromol. Chem. 187, 1131-1144.
-
(1986)
Makromol. Chem.
, vol.187
, pp. 1131-1144
-
-
Ulbrich, K.1
Strohalm, J.2
Kopecek, J.3
-
67
-
-
0019324174
-
Degradation of side chains of N-(2-hydroxypropyl)methacrylamide copolymers by lysosomal enzymes
-
Duncan, R., Lloyd, J.B. and Kopecek, J.(1980) Degradation of side chains of N-(2-hydroxypropyl)methacrylamide copolymers by lysosomal enzymes. Biochem. Biophys. Res. Commun. 94, 284-290.
-
(1980)
Biochem. Biophys. Res. Commun.
, vol.94
, pp. 284-290
-
-
Duncan, R.1
Lloyd, J.B.2
Kopecek, J.3
-
68
-
-
0009975408
-
Polymer-bound derivatives of sarcolysin and their antitumour activities against mouse and human leukaemia in vitro
-
Ulbrich, K., Zachaneva, E.I., Kopecek, J., Hume, I.C. and Duncan, R. (1987) Polymer-bound derivatives of sarcolysin and their antitumour activities against mouse and human leukaemia in vitro. Makromol. Chem. 188, 2497-2509.
-
(1987)
Makromol. Chem.
, vol.188
, pp. 2497-2509
-
-
Ulbrich, K.1
Zachaneva, E.I.2
Kopecek, J.3
Hume, I.C.4
Duncan, R.5
-
69
-
-
0022002504
-
Stability in rat plasma and serum of lysosomally degradable oligopeptide sequences in N-(2-hydroxypropyl)methacrylamide copolymers
-
Rejmanova, P., Kopecek, J., Duncan, R. and Lloyd, J.B. (1985) Stability in rat plasma and serum of lysosomally degradable oligopeptide sequences in N-(2-hydroxypropyl)methacrylamide copolymers. Biomaterials 6, 45-48.
-
(1985)
Biomaterials
, vol.6
, pp. 45-48
-
-
Rejmanova, P.1
Kopecek, J.2
Duncan, R.3
Lloyd, J.B.4
-
70
-
-
0026584015
-
Polymers containing enzymatically degradable bonds. XII. Effect of spacer structure on the rate of release of daunomycin and adriamycin from poly[N-(2-hydroxypropyl)methacrylamide] copolymer drug carriers in vitro and antitumour activity measured in vivo
-
Subr, V., Strohalm, J., Ulbrich, K., Duncan, R. and Hume, I.C. (1992) Polymers containing enzymatically degradable bonds. XII. Effect of spacer structure on the rate of release of daunomycin and adriamycin from poly[N-(2-hydroxypropyl)methacrylamide] copolymer drug carriers in vitro and antitumour activity measured in vivo. J. Control. Release 18, 123-132.
-
(1992)
J. Control. Release
, vol.18
, pp. 123-132
-
-
Subr, V.1
Strohalm, J.2
Ulbrich, K.3
Duncan, R.4
Hume, I.C.5
-
71
-
-
0025359853
-
The pharmacokinetics of polymer-bound adriamycin
-
Seymour, L.W., Ulbrich, K., Strohalm, J., Kopecek, J. and Duncan, R. (1990) The pharmacokinetics of polymer-bound adriamycin. Biochem. Pharmacol. 39, 1125-1131.
-
(1990)
Biochem. Pharmacol.
, vol.39
, pp. 1125-1131
-
-
Seymour, L.W.1
Ulbrich, K.2
Strohalm, J.3
Kopecek, J.4
Duncan, R.5
-
72
-
-
0025856232
-
Macromolecular prodrugs for use in targeted cancer chemotherapy; melphalan covalently coupled to N-(2-hydroxypropyl)methacrylamide copolymers
-
Duncan, R., Hume, I.C., Yardley, H.J., Flanagan, P.A., Ulbrich, K., Subr, V. and Strohalm, J., (1991) Macromolecular prodrugs for use in targeted cancer chemotherapy; melphalan covalently coupled to N-(2-hydroxypropyl)methacrylamide copolymers. J. Control. Release 16, 121-136.
-
(1991)
J. Control. Release
, vol.16
, pp. 121-136
-
-
Duncan, R.1
Hume, I.C.2
Yardley, H.J.3
Flanagan, P.A.4
Ulbrich, K.5
Subr, V.6
Strohalm, J.7
-
73
-
-
0026561607
-
Preclinical evaluation of polymer-bound doxorubicin
-
Duncan, R., Seymour, L.W., O'Hare, K.B., Flanagan, P., Wedge, S., Hume, I.C., Ulbrich, K., Strohalm, J., Subr, V., Spreafico, F., Grandi, M., Ripamonti, M., Farao, M. and Surato, A. (1992) Preclinical evaluation of polymer-bound doxorubicin. J. Control. Release 19, 331-346.
-
(1992)
J. Control. Release
, vol.19
, pp. 331-346
-
-
Duncan, R.1
Seymour, L.W.2
O'Hare, K.B.3
Flanagan, P.4
Wedge, S.5
Hume, I.C.6
Ulbrich, K.7
Strohalm, J.8
Subr, V.9
Spreafico, F.10
Grandi, M.11
Ripamonti, M.12
Farao, M.13
Surato, A.14
-
74
-
-
0028030559
-
Tumour tropism and anti-cancer efficacy of polymer-bound doxorubicin prodrugs in the treatment of subcutaneous murine B16F10 melanoma
-
Seymour, L.W., Ulbrich, K., Steyger, P.S., Brereton, M., Subr, V., Strohalm, J. and Duncan, R. (1994) Tumour tropism and anti-cancer efficacy of polymer-bound doxorubicin prodrugs in the treatment of subcutaneous murine B16F10 melanoma. Br. J. Cancer 70, 636-641.
-
(1994)
Br. J. Cancer
, vol.70
, pp. 636-641
-
-
Seymour, L.W.1
Ulbrich, K.2
Steyger, P.S.3
Brereton, M.4
Subr, V.5
Strohalm, J.6
Duncan, R.7
-
75
-
-
0027390175
-
Biological properties of adriamycin bound to biodegradable polymeric carriers
-
Hoes, C.J.T., Grootoonk, J., Duncan, R., Hume, I.C., Bhakoo, M., Bouma, J.M.W, and Feijen, J. (1993) Biological properties of adriamycin bound to biodegradable polymeric carriers. J. Control. Release 23, 37-54.
-
(1993)
J. Control. Release
, vol.23
, pp. 37-54
-
-
Hoes, C.J.T.1
Grootoonk, J.2
Duncan, R.3
Hume, I.C.4
Bhakoo, M.5
Bouma, J.M.W.6
Feijen, J.7
-
76
-
-
0028023917
-
Evaluation of the hydrolytic and enzymatic stability of macromolecular mitomycin C derivatives
-
De Marre, A., Seymour, L.W. and Schacht, E. (1994) Evaluation of the hydrolytic and enzymatic stability of macromolecular mitomycin C derivatives. J. Control. Release 31, 89-97.
-
(1994)
J. Control. Release
, vol.31
, pp. 89-97
-
-
De Marre, A.1
Seymour, L.W.2
Schacht, E.3
-
77
-
-
0024243003
-
Cleavage of oligopeptide side chains in N-(2-hydroxypropyl)methacrylamide copolymers by mixtures of lysosomal enzymes
-
Subr, V., Kopecek, J., Pohl, J., Baudys, M. and Kostka, V. (1988) Cleavage of oligopeptide side chains in N-(2-hydroxypropyl)methacrylamide copolymers by mixtures of lysosomal enzymes. J. Control. Release 8, 133-140.
-
(1988)
J. Control. Release
, vol.8
, pp. 133-140
-
-
Subr, V.1
Kopecek, J.2
Pohl, J.3
Baudys, M.4
Kostka, V.5
-
78
-
-
0015526064
-
Chemotherapy through lysosome with a DNA-daunomycin complex
-
Trouet, A., Deprez-De Campeneere, D. and De Duve, C. (1972) Chemotherapy through lysosome with a DNA-daunomycin complex. Nat. New Biol. 239, 110-112.
-
(1972)
Nat. New Biol.
, vol.239
, pp. 110-112
-
-
Trouet, A.1
Deprez-De Campeneere, D.2
De Duve, C.3
-
79
-
-
0006052482
-
A covalent linkage between daunomycin and proteins that is stable in serum and reversable by lysosomal hydrolases, as required for a lysosomotropic drug-carrier conjugate; in vitro and in vivo studies
-
Trouet, A., Masquelier, M., Baurain, R. and Deprez-De Campeneere, D. (1982) A covalent linkage between daunomycin and proteins that is stable in serum and reversable by lysosomal hydrolases, as required for a lysosomotropic drug-carrier conjugate; in vitro and in vivo studies. Proc. Natl. Acad. Sci. USA 79, 626-629.
-
(1982)
Proc. Natl. Acad. Sci. USA
, vol.79
, pp. 626-629
-
-
Trouet, A.1
Masquelier, M.2
Baurain, R.3
Deprez-De Campeneere, D.4
-
80
-
-
0019287522
-
Amino acid and dipeptide derivatives of daunorubicin. 1. Synthesis, physicochemical properties and lysosomal digestion
-
Masquelier, M., Baurain, R. and Trouet, A. (1980) Amino acid and dipeptide derivatives of daunorubicin. 1. Synthesis, physicochemical properties and lysosomal digestion. J. Med. Chem. 23, 1166-1170.
-
(1980)
J. Med. Chem.
, vol.23
, pp. 1166-1170
-
-
Masquelier, M.1
Baurain, R.2
Trouet, A.3
-
81
-
-
0019301927
-
Amino acid and dipeptide derivatives of daunorubicin. 2. Cellular pharmacology and antitumour activity on L1210 leukemic cells in vitro and in vivo
-
Baurain, R., Masquelier, M., Deprez-De Campeneere, D. and Trouet, A. (1980) Amino acid and dipeptide derivatives of daunorubicin. 2. Cellular pharmacology and antitumour activity on L1210 leukemic cells in vitro and in vivo. J. Med. Chem. 23, 1171-1174.
-
(1980)
J. Med. Chem.
, vol.23
, pp. 1171-1174
-
-
Baurain, R.1
Masquelier, M.2
Deprez-De Campeneere, D.3
Trouet, A.4
-
82
-
-
0024410772
-
Soluble macromolecular carriers for the delivery of antitumour drugs
-
Sezaki, H., Takakura, Y. and Hashida, M. (1989) Soluble macromolecular carriers for the delivery of antitumour drugs. Adv. Drug Deliv. Rev. 3, 247-266.
-
(1989)
Adv. Drug Deliv. Rev.
, vol.3
, pp. 247-266
-
-
Sezaki, H.1
Takakura, Y.2
Hashida, M.3
-
83
-
-
0023692977
-
Some aspects of the application of dextran in prodrug design
-
Schacht, E., Vercauteren, R. and Vansteenkiste, S. (1988) Some aspects of the application of dextran in prodrug design. J. Bioact. Compatible Polym. 3, 72-80.
-
(1988)
J. Bioact. Compatible Polym.
, vol.3
, pp. 72-80
-
-
Schacht, E.1
Vercauteren, R.2
Vansteenkiste, S.3
-
84
-
-
0025181633
-
Alteration of biopharmaceutical properties of drugs by their conjugation with water-soluble macromolecules; uricase-dextran conjugates
-
Fujita, T., Yasuda, Y., Takakura, Y., Hashida, M. and Sezaki, H. (1990) Alteration of biopharmaceutical properties of drugs by their conjugation with water-soluble macromolecules; uricase-dextran conjugates. J. Control. Release 11, 149-156.
-
(1990)
J. Control. Release
, vol.11
, pp. 149-156
-
-
Fujita, T.1
Yasuda, Y.2
Takakura, Y.3
Hashida, M.4
Sezaki, H.5
-
85
-
-
0010352648
-
Polysaccharide macromolecules as drug carriers
-
L. Ilium and S.S. Davis (Eds), Wright, Bristol, UK
-
Schacht, E. (1987) Polysaccharide macromolecules as drug carriers. In: L. Ilium and S.S. Davis (Eds), Polymers in Controlled Delivery, Wright, Bristol, UK, pp. 131-151.
-
(1987)
Polymers in Controlled Delivery
, pp. 131-151
-
-
Schacht, E.1
-
86
-
-
0026939267
-
Effect of chemical modification of dextran on the degradation by rat liver lysosomal enzymes
-
Vercauteren, R., Schacht, E. and Duncan, R. (1992) Effect of chemical modification of dextran on the degradation by rat liver lysosomal enzymes. J. Bioact. Compatible Polym. 7, 346-357.
-
(1992)
J. Bioact. Compatible Polym.
, vol.7
, pp. 346-357
-
-
Vercauteren, R.1
Schacht, E.2
Duncan, R.3
-
87
-
-
0025824046
-
Enzymatic degradation and immunogenic properties of derivatised dextrans
-
Crepon, B., Jozefonvicz, J., Chytry, V., Rihova, B. and Kopecek, J. (1991) Enzymatic degradation and immunogenic properties of derivatised dextrans. Biomaterials 12, 550-554.
-
(1991)
Biomaterials
, vol.12
, pp. 550-554
-
-
Crepon, B.1
Jozefonvicz, J.2
Chytry, V.3
Rihova, B.4
Kopecek, J.5
-
88
-
-
0028517591
-
Enzymatic degradation of poly(ethylene glycol) modified dextrans
-
Chiu, H.-C., Konak, C., Kopeckova, P. and Kopecek, J. (1994) Enzymatic degradation of poly(ethylene glycol) modified dextrans. J. Bioact. Compatible Polym. 19, 388-410.
-
(1994)
J. Bioact. Compatible Polym.
, vol.19
, pp. 388-410
-
-
Chiu, H.-C.1
Konak, C.2
Kopeckova, P.3
Kopecek, J.4
-
90
-
-
0024461551
-
Physicochemical properties and antitumour activities of polymeric prodrugs of mitomycin C with different regeneration rates
-
Takakura, Y., Matsumoto, S., Hashida, M. and Sezaki, H. (1989) Physicochemical properties and antitumour activities of polymeric prodrugs of mitomycin C with different regeneration rates. J. Control. Release 10, 97-105.
-
(1989)
J. Control. Release
, vol.10
, pp. 97-105
-
-
Takakura, Y.1
Matsumoto, S.2
Hashida, M.3
Sezaki, H.4
-
91
-
-
0022273726
-
Use of polysaccharides as drug carriers. Dextran and inulin derivatives of procainamide
-
Schacht, E., Ruys, L., Vermeersch, J., Remon, J.P. and Duncan, R. (1985) Use of polysaccharides as drug carriers. Dextran and inulin derivatives of procainamide. Ann. NY Acad. Sci. 446, 199-212
-
(1985)
Ann. NY Acad. Sci.
, vol.446
, pp. 199-212
-
-
Schacht, E.1
Ruys, L.2
Vermeersch, J.3
Remon, J.P.4
Duncan, R.5
-
92
-
-
0021875585
-
Synthesis of succinoylated inulin and applications as a carrier for procainamide
-
Vermeersch, J. and Schacht, E. (1985) Synthesis of succinoylated inulin and applications as a carrier for procainamide. Bull. Soc. Chim. Belg. 94, 287-291.
-
(1985)
Bull. Soc. Chim. Belg.
, vol.94
, pp. 287-291
-
-
Vermeersch, J.1
Schacht, E.2
-
93
-
-
0000928583
-
Synthesis and characterisation of inulin monosaccharides
-
Vermeersch, J. and Schacht, E. (1986) Synthesis and characterisation of inulin monosaccharides. Makromol. Chem. 187, 125-131.
-
(1986)
Makromol. Chem.
, vol.187
, pp. 125-131
-
-
Vermeersch, J.1
Schacht, E.2
-
94
-
-
0022405518
-
Optimization of macromolecular prodrugs of the anti-tumor antibiotic adriamycin
-
Hoes, C.J.T., Potman, W., van Heeswijk, W.A.R., Mud, J., de Grooth, B.C., Greve, J. and Feijen, J. (1985) Optimization of macromolecular prodrugs of the anti-tumor antibiotic adriamycin. J. Control. Release 2, 205-213.
-
(1985)
J. Control. Release
, vol.2
, pp. 205-213
-
-
Hoes, C.J.T.1
Potman, W.2
Van Heeswijk, W.A.R.3
Mud, J.4
De Grooth, B.C.5
Greve, J.6
Feijen, J.7
-
95
-
-
0021853012
-
The synthesis and charcterisation of polypeptide adriamycin conjugates and its complexes with adriamycin. Part 1
-
van Heeswijk, W.A.R., Hoes, C.J.T., Stoffer, T., Eenink, M.J.D., Potman, W. and Feijen, J. (1985) The synthesis and charcterisation of polypeptide adriamycin conjugates and its complexes with adriamycin. Part 1. J. Control. Release 1, 301-315.
-
(1985)
J. Control. Release
, vol.1
, pp. 301-315
-
-
Van Heeswijk, W.A.R.1
Hoes, C.J.T.2
Stoffer, T.3
Eenink, M.J.D.4
Potman, W.5
Feijen, J.6
-
96
-
-
0024443207
-
Soluble polymers as carriers of cis-platinum
-
Schechter, B., Neumann, A., Wilchek, M. and Arnon, R. (1989) Soluble polymers as carriers of cis-platinum. J. Control. Release 10, 75-87.
-
(1989)
J. Control. Release
, vol.10
, pp. 75-87
-
-
Schechter, B.1
Neumann, A.2
Wilchek, M.3
Arnon, R.4
-
97
-
-
0024787085
-
N-[[2-(Trimethylsilyl)ethoxy]carbonyl] derivatives of tri-L-lysine and tetra-L-lysine as potential intermediates in block polymer synthesis of macromolecular drug conjugates
-
Rosowsky, A. and Wright, J.E. (1989) N-[[2-(Trimethylsilyl)ethoxy]carbonyl] derivatives of tri-L-lysine and tetra-L-lysine as potential intermediates in block polymer synthesis of macromolecular drug conjugates. J. Org. Chem. 54, 5551-5558.
-
(1989)
J. Org. Chem.
, vol.54
, pp. 5551-5558
-
-
Rosowsky, A.1
Wright, J.E.2
-
98
-
-
0028997949
-
In vitro cytotoxicity of macromolecules in different cell culture systems
-
Choksakulnimitr. S., Masuda, S., Tokuda, H., Takakura, Y. and Hashida, M. (1995) In vitro cytotoxicity of macromolecules in different cell culture systems. J. Control. Release 34, 233-241.
-
(1995)
J. Control. Release
, vol.34
, pp. 233-241
-
-
Choksakulnimitr, S.1
Masuda, S.2
Tokuda, H.3
Takakura, Y.4
Hashida, M.5
-
99
-
-
0027988268
-
Immunogenicity of poly-D-lysine, a potential polymeric drug carrier
-
Vermeersch, H. and Remon, J.P. (1994) Immunogenicity of poly-D-lysine, a potential polymeric drug carrier. J. Control. Release 32, 225-229.
-
(1994)
J. Control. Release
, vol.32
, pp. 225-229
-
-
Vermeersch, H.1
Remon, J.P.2
-
100
-
-
0026658483
-
Antileishmanial drug targeting through glycosylated polymers specifically internalised by macrophage membrane lectins
-
Negre, E., Chance, M.L., Hanboula, S.Y., Monsigny, M., Roche, A.-C., Mayer, R.M and Hommel, M. (1992) Antileishmanial drug targeting through glycosylated polymers specifically internalised by macrophage membrane lectins. Antimicrob. Agents Chemother. 36, 2228-2232.
-
(1992)
Antimicrob. Agents Chemother.
, vol.36
, pp. 2228-2232
-
-
Negre, E.1
Chance, M.L.2
Hanboula, S.Y.3
Monsigny, M.4
Roche, A.-C.5
Mayer, R.M.6
Hommel, M.7
-
101
-
-
0025306405
-
Drug targeting: Anti-HSV-1 activity of mannosylated polymer-bound 9-(2-phosponylmethoxyethyl) adenine
-
Midoux, P., Negre, E., Roche, A.-C., Mayer, R., Monsigny, M., Balzarini, J., De Clercq, E., Mayer, E., Ghaffer, A. and Gangemi, J.D. (1990) Drug targeting: anti-HSV-1 activity of mannosylated polymer-bound 9-(2-phosponylmethoxyethyl) adenine. Biochem. Biophys. Res. Commun.167, 1044-1049.
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.167
, pp. 1044-1049
-
-
Midoux, P.1
Negre, E.2
Roche, A.-C.3
Mayer, R.4
Monsigny, M.5
Balzarini, J.6
De Clercq, E.7
Mayer, E.8
Ghaffer, A.9
Gangemi, J.D.10
-
102
-
-
0026509615
-
Carrier design: Cytotoxicity and immunogenicity of synthetic branched polypeptides with poly(L-lysine) backbone
-
Hudecz, F., Gaal, D., Kurucz, I., Lanyi, A., Kovacs, A.L., Mezo, G., Rajnavolgyi, E. and Szekerke, M. (1992) Carrier design: cytotoxicity and immunogenicity of synthetic branched polypeptides with poly(L-lysine) backbone. J. Control. Release 19, 231-244.
-
(1992)
J. Control. Release
, vol.19
, pp. 231-244
-
-
Hudecz, F.1
Gaal, D.2
Kurucz, I.3
Lanyi, A.4
Kovacs, A.L.5
Mezo, G.6
Rajnavolgyi, E.7
Szekerke, M.8
-
103
-
-
0343389727
-
Preparation of 4-nitrophenol carborate esters of poly[N-5-(2-hydroxyethyl)-L-glutamine] and coupling with bioactive agents
-
De Marre, A. and Schacht, E. (1992) Preparation of 4-nitrophenol carborate esters of poly[N-5-(2-hydroxyethyl)-L-glutamine] and coupling with bioactive agents. Makromol. Chem. 193, 3023-3030.
-
(1992)
Makromol. Chem.
, vol.193
, pp. 3023-3030
-
-
De Marre, A.1
Schacht, E.2
-
104
-
-
0028004494
-
Synthesis of mitomycin C derivatives
-
De Marre, A., Soyez, H. and Schacht, E. (1994) Synthesis of mitomycin C derivatives. J. Control. Release 32, 129-137.
-
(1994)
J. Control. Release
, vol.32
, pp. 129-137
-
-
De Marre, A.1
Soyez, H.2
Schacht, E.3
-
105
-
-
0024431093
-
Poly(N-hydroxyalkylglutamine)s. IV. Enzymatic degradation of N-(2-hydroxyethyl)-L-glutamine homopolymer and copolymers
-
J.
-
Pytela, J., Saudek, V., Drobnik and J., Rypacek, F. (1989) Poly(N-hydroxyalkylglutamine)s. IV. Enzymatic degradation of N-(2-hydroxyethyl)-L-glutamine homopolymer and copolymers. J. Control. Release 10, 17-25.
-
(1989)
J. Control. Release
, vol.10
, pp. 17-25
-
-
Pytela, J.1
Saudek, V.2
Rypacek, F.3
-
106
-
-
0027502293
-
5-hydroxyethyl-L-glutamine-co-L-glutamic acid copolymer in rats
-
5-hydroxyethyl-L-glutamine-co-L-glutamic acid copolymer in rats. J. Bioact. Compatible Polym. 8, 51-68.
-
(1993)
J. Bioact. Compatible Polym.
, vol.8
, pp. 51-68
-
-
Bayley, D.1
Sancho, M.-R.2
Brown, J.3
Brookman, L.4
Petrak, K.5
Goddard, P.6
Steward, A.7
-
107
-
-
0023439177
-
Reaction of α,β-poly(N-hydroxyethyl)-DL-aspartamide with derivatives of carboxylic acids
-
1987
-
Giammona, G., Carlisi, B. and Palazzo, S. (1987) Reaction of α,β-(poly(N-hydroxyethyl)-DL-aspartamide with derivatives of carboxylic acids. J. Polym. Sci. Polym. Chem., 1987, 25, 2813-2818.
-
(1987)
J. Polym. Sci. Polym. Chem.
, vol.25
, pp. 2813-2818
-
-
Giammona, G.1
Carlisi, B.2
Palazzo, S.3
-
108
-
-
0028911019
-
Chemical stability and bioavailability of acyclovir coupled to a,β-poly(N-hydroxyethyl)-DL-aspartamide
-
Giammona, G., Puglisi, G., Cavallaro, G., Spadaro, A. and Pitarresi, G. (1995) Chemical stability and bioavailability of acyclovir coupled to a,β-(poly(N-hydroxyethyl)-DL-aspartamide. J. Control. Release 33, 261-271.
-
(1995)
J. Control. Release
, vol.33
, pp. 261-271
-
-
Giammona, G.1
Puglisi, G.2
Cavallaro, G.3
Spadaro, A.4
Pitarresi, G.5
-
109
-
-
0000184027
-
Reactive copolymers of N-(2-hydroxypropyl)methacrylamide with N-methacryloated derivatives of L-leucine and L-phenylalanine
-
Kopecek, J. (1977) Reactive copolymers of N-(2-hydroxypropyl)methacrylamide with N-methacryloated derivatives of L-leucine and L-phenylalanine. Makromol. Chem. 178, 2169-2183.
-
(1977)
Makromol. Chem.
, vol.178
, pp. 2169-2183
-
-
Kopecek, J.1
-
110
-
-
0001023307
-
Covalent attachment of chymotrypsin to poly[N-(2-hydroxypropyl)methacrylamide]
-
Lääne, A., Chytry, V., Haga, M., Sikk, P., Aaviksaar, A. and Kopecek, J. (1981) Covalent attachment of chymotrypsin to poly[N-(2-hydroxypropyl)methacrylamide]. Coll. Czech. Chem. Commun. 46, 1466-1473.
-
(1981)
Coll. Czech. Chem. Commun.
, vol.46
, pp. 1466-1473
-
-
Lääne, A.1
Chytry, V.2
Haga, M.3
Sikk, P.4
Aaviksaar, A.5
Kopecek, J.6
-
111
-
-
0011338304
-
Activation of poly[N-(2-hydroxypropyl)methacrylamide] for the binding of bioactive molecules
-
Lääne, A., Haga, M., Aaviksaar, A., Chytry, V. and Kopecek, J. (1983) Activation of poly[N-(2-hydroxypropyl)methacrylamide] for the binding of bioactive molecules. Makromol. Chem. 184, 1339-1344.
-
(1983)
Makromol. Chem.
, vol.184
, pp. 1339-1344
-
-
Lääne, A.1
Haga, M.2
Aaviksaar, A.3
Chytry, V.4
Kopecek, J.5
-
112
-
-
0042436966
-
Activation of poly[N-(2-hydroxypropyl)methacrylamide] for the binding of bioactive molecules. 1. Activation with 4-nitrophenol chloroformate
-
Chytry, V. and Kopecek, J. (1983) Activation of poly[N-(2-hydroxypropyl)methacrylamide] for the binding of bioactive molecules. 1. Activation with 4-nitrophenol chloroformate. Makromol. Chem. 184, 1345-1353.
-
(1983)
Makromol. Chem.
, vol.184
, pp. 1345-1353
-
-
Chytry, V.1
Kopecek, J.2
-
113
-
-
0000932483
-
Aminolysis of monomeric and polymeric 4-nitrophenol esters of N-methacryloylamino acids
-
Rejmanova, P., Labsky, J. and Kopecek, J. (1977) Aminolysis of monomeric and polymeric 4-nitrophenol esters of N-methacryloylamino acids. Makromol. Chem. 178, 2159-2168.
-
(1977)
Makromol. Chem.
, vol.178
, pp. 2159-2168
-
-
Rejmanova, P.1
Labsky, J.2
Kopecek, J.3
-
114
-
-
0019491361
-
Drug polymer combinations. III. Synthesis of the methacrylamide derivative of procainamide and its homopolymer
-
Scahcht, E., Ruys, L., Goethals, E., Gyselinck, P., Van Severen, R. and Braeckmann, P. (1981) Drug polymer combinations. III. Synthesis of the methacrylamide derivative of procainamide and its homopolymer. J. Pharm. Belg. 36, 113-117.
-
(1981)
J. Pharm. Belg.
, vol.36
, pp. 113-117
-
-
Scahcht, E.1
Ruys, L.2
Goethals, E.3
Gyselinck, P.4
Van Severen, R.5
Braeckmann, P.6
-
115
-
-
0024398880
-
Biocompatibility of N-(2-hydroxypropyl)methacrylamide copolymers containing adriamycin
-
Rihova, B., Bilej, M., Vetvicka, V., Ulbrich, K., Strohalm, J., Kopecek, J. and Duncan, R. (1989) Biocompatibility of N-(2-hydroxypropyl)methacrylamide copolymers containing adriamycin. Biomaterials 10, 335-342.
-
(1989)
Biomaterials
, vol.10
, pp. 335-342
-
-
Rihova, B.1
Bilej, M.2
Vetvicka, V.3
Ulbrich, K.4
Strohalm, J.5
Kopecek, J.6
Duncan, R.7
-
116
-
-
0023129812
-
Soluble cross-linked N-(2-hydroxypropyl)methacrylamide copolymers as potential drug carriers. 3. Targeting by incorporation of galactosamine residues. Effect of route of administration
-
Cartlidge, S.A., Duncan, R., Lloyd, J.B., KopeckovaRejmanova, P. and Kopecek, J. (1987) Soluble cross-linked N-(2-hydroxypropyl)methacrylamide copolymers as potential drug carriers. 3. Targeting by incorporation of galactosamine residues. Effect of route of administration. J. Control. Release 4, 265-278.
-
(1987)
J. Control. Release
, vol.4
, pp. 265-278
-
-
Cartlidge, S.A.1
Duncan, R.2
Lloyd, J.B.3
Kopeckovarejmanova, P.4
Kopecek, J.5
-
117
-
-
0001288059
-
Polymers containing enzymatically degradable bonds. 2. Poly[N-(2-hydroxypropyl)methacrylamide] chains connected by oligopeptide sequences cleavable by chymotrypsin
-
Rejmanova, P., Obereigner, B. and Kopecek, J.(1981) Polymers containing enzymatically degradable bonds. 2. Poly[N-(2-hydroxypropyl)methacrylamide] chains connected by oligopeptide sequences cleavable by chymotrypsin. Makromol. Chem., 1981, 182, 1899-1915.
-
(1981)
Makromol. Chem.
, vol.1981
, pp. 182
-
-
Rejmanova, P.1
Obereigner, B.2
Kopecek, J.3
-
118
-
-
0001288056
-
Polymers containing enzymatically degradable bonds. 3. Poly[N-(2-hydroxypropyl)methacrylamide] chains connected by oligopeptide sequences cleavable by trypsin
-
Ulbrich, K., Strohalm, J. and Kopecek, J. (1981) Polymers containing enzymatically degradable bonds. 3. Poly[N-(2-hydroxypropyl)methacrylamide] chains connected by oligopeptide sequences cleavable by trypsin. Makromol. Chem. 182, 1917-1928.
-
(1981)
Makromol. Chem.
, vol.182
, pp. 1917-1928
-
-
Ulbrich, K.1
Strohalm, J.2
Kopecek, J.3
-
119
-
-
0019218032
-
Polymers containing enzymatically degradable bonds. 5. Hydrophilic polymers degradable by papain
-
Ulbrich, K., Zacharieva, E.I., Obereigner, B. and Kopecek, J. (1980) Polymers containing enzymatically degradable bonds. 5. Hydrophilic polymers degradable by papain. Biomaterials 1, 199-204.
-
(1980)
Biomaterials
, vol.1
, pp. 199-204
-
-
Ulbrich, K.1
Zacharieva, E.I.2
Obereigner, B.3
Kopecek, J.4
-
120
-
-
0023102353
-
Soluble cross-linked N-(2-hydroxypropyl)methacrylamide copolymers as potential drug carriers. 2. Effect of molecular weight on blood clearance and body distribution in the rat after intravenous administration
-
Cartridge, S.A., Duncan, R., Lloyd, J.B., Kopeckova-Rejmanova, P. and Kopecek, J. (1987) Soluble cross-linked N-(2-hydroxypropyl)methacrylamide copolymers as potential drug carriers. 2. Effect of molecular weight on blood clearance and body distribution in the rat after intravenous administration. J. Control. Release 4, 253-264.
-
(1987)
J. Control. Release
, vol.4
, pp. 253-264
-
-
Cartridge, S.A.1
Duncan, R.2
Lloyd, J.B.3
Kopeckova-Rejmanova, P.4
Kopecek, J.5
-
121
-
-
0025099302
-
The potential of water-soluble polymeric carriers in targeted and site-specific drug delivery
-
Kopecek, J. (1990) The potential of water-soluble polymeric carriers in targeted and site-specific drug delivery. J. Control. Release 11, 279-290.
-
(1990)
J. Control. Release
, vol.11
, pp. 279-290
-
-
Kopecek, J.1
-
122
-
-
0021274948
-
Effect of the chemical structure of N-(2-hydroxypropyl)methacrylamide copolymers on their ability to induce antibody formation in inbred strains of mice
-
Rihova, B., Kopecek, J., Ulbrich, K., Popisil, M. and Mancal, P. (1984) Effect of the chemical structure of N-(2-hydroxypropyl)methacrylamide copolymers on their ability to induce antibody formation in inbred strains of mice. Biomaterials 5, 143-148.
-
(1984)
Biomaterials
, vol.5
, pp. 143-148
-
-
Rihova, B.1
Kopecek, J.2
Ulbrich, K.3
Popisil, M.4
Mancal, P.5
-
123
-
-
0027429220
-
Effect of pre-immunisation on the activity of polymer-doxorubicin against mouse L1210 leukaemia
-
Flanagan, P.A., Strohalm, J., Ulbrich, K. and Duncan, R. (1993) Effect of pre-immunisation on the activity of polymer-doxorubicin against mouse L1210 leukaemia. J. Control. Release 26, 221-228.
-
(1993)
J. Control. Release
, vol.26
, pp. 221-228
-
-
Flanagan, P.A.1
Strohalm, J.2
Ulbrich, K.3
Duncan, R.4
-
124
-
-
0027253357
-
The conjugation of proteins with polyethylene glycol and other polymers. Altering properties to enhance their therapeutic potential
-
Katre, N.V. (1993) The conjugation of proteins with polyethylene glycol and other polymers. Altering properties to enhance their therapeutic potential. Adv. Drug Deliv. Rev., 10, 91-114.
-
(1993)
Adv. Drug Deliv. Rev.
, vol.10
, pp. 91-114
-
-
Katre, N.V.1
-
125
-
-
0024558259
-
Effects of coupling chemistry on the activity of poly(ethylene glycol)-modified alkaline phosphatases
-
Yoshinga, K. and Harris, J.M. (1989) Effects of coupling chemistry on the activity of poly(ethylene glycol)-modified alkaline phosphatases J. Bioact. Compatible Polym. 4, 17-24.
-
(1989)
J. Bioact. Compatible Polym.
, vol.4
, pp. 17-24
-
-
Yoshinga, K.1
Harris, J.M.2
-
126
-
-
0025019752
-
The clinical efficacy of poly(ethylene glycol)-modified proteins
-
Fuertges, F. and Abuchowski, A. (1990) The clinical efficacy of poly(ethylene glycol)-modified proteins. J. Control. Release 11, 139-148.
-
(1990)
J. Control. Release
, vol.11
, pp. 139-148
-
-
Fuertges, F.1
Abuchowski, A.2
-
127
-
-
0000992727
-
End group modification of α-hydroxy-ω-methoxypoly(oxyethylene) - Facile methods for the introduction of a α-amino end group
-
Loccufier, J., Cremmon, J., Vadorpe, J. and Schacht E. (1991) End group modification of α-hydroxy-ω-methoxypoly(oxyethylene) - facile methods for the introduction of a α-amino end group. Makromol. Chem. Rapid Commun. 12, 159-165.
-
(1991)
Makromol. Chem. Rapid Commun.
, vol.12
, pp. 159-165
-
-
Loccufier, J.1
Cremmon, J.2
Vadorpe, J.3
Schacht, E.4
-
128
-
-
0009890182
-
Synthesis of a new family of poly(amido amine)s carrying poly(oxyethylene) side chains
-
Vansteenkiste, S., Schacht, E., Ranucci, E. and Ferruti, P. (1992) Synthesis of a new family of poly(amido amine)s carrying poly(oxyethylene) side chains. Makromol. Chem. 193, 937-943.
-
(1992)
Makromol. Chem.
, vol.193
, pp. 937-943
-
-
Vansteenkiste, S.1
Schacht, E.2
Ranucci, E.3
Ferruti, P.4
-
129
-
-
0022660909
-
Preparation of cyanuric chloride activated poly(ethylene glycol)
-
Shafer, S.G. and Harris, J.M.. (1986) Preparation of cyanuric chloride activated poly(ethylene glycol). J. Polym. Sci. Polym. Chem. 24, 375-378.
-
(1986)
J. Polym. Sci. Polym. Chem.
, vol.24
, pp. 375-378
-
-
Shafer, S.G.1
Harris, J.M.2
-
130
-
-
0026124772
-
The therapeutic value of poly(ethylene glycol)-modified proteins
-
Nucci, M.L., Shorr, R. and Abuchowski, A. (1991) The therapeutic value of poly(ethylene glycol)-modified proteins. Adv. Drug Deliv. Rev. 6, 133-151.
-
(1991)
Adv. Drug Deliv. Rev.
, vol.6
, pp. 133-151
-
-
Nucci, M.L.1
Shorr, R.2
Abuchowski, A.3
-
131
-
-
0026438972
-
The uses and properties of PEG-linked proteins
-
Delgado, C., Francis, G.E. and Fisher, D.(1992) The uses and properties of PEG-linked proteins. CRC Crit. Rev. Ther. Drug Carrier Syst. 9, 249-304.
-
(1992)
CRC Crit. Rev. Ther. Drug Carrier Syst.
, vol.9
, pp. 249-304
-
-
Delgado, C.1
Francis, G.E.2
Fisher, D.3
-
132
-
-
0026812687
-
Evaluation of a new reagent for covalent attachment of polyethylene glycol to proteins
-
Zalipsky, S., Seltzer, R. and Menon-Rudolph, S. (1992) Evaluation of a new reagent for covalent attachment of polyethylene glycol to proteins. Biotech. Appl. Biochem. 15, 100-114.
-
(1992)
Biotech. Appl. Biochem.
, vol.15
, pp. 100-114
-
-
Zalipsky, S.1
Seltzer, R.2
Menon-Rudolph, S.3
-
133
-
-
0343389697
-
PEG activation and ligand binding and the affinity partitioning of proteins in aqueous two-phase systems
-
Andrews, B.A., Head, D.M., Dunthorne, P. and Asenjo, J. A. (1990) PEG activation and ligand binding and the affinity partitioning of proteins in aqueous two-phase systems. Biotech. Tech. 4, 49-54.
-
(1990)
Biotech. Tech.
, vol.4
, pp. 49-54
-
-
Andrews, B.A.1
Head, D.M.2
Dunthorne, P.3
Asenjo, J.A.4
-
134
-
-
3142696444
-
Epoxy-oxirane activation of PEG for protein ligand coupling
-
Head, D.M., Andrews, B.A. and Asenjo, J.A. (1989) Epoxy-oxirane activation of PEG for protein ligand coupling. Biotech. Tech. 3, 27-32.
-
(1989)
Biotech. Tech.
, vol.3
, pp. 27-32
-
-
Head, D.M.1
Andrews, B.A.2
Asenjo, J.A.3
-
135
-
-
0027344774
-
Copolymers of lysine and polyethylene glycols; a new family of functionalized drug carriers
-
Nathan, A., Zalipsky, S., Ertel, S.I., Agathos, S.N., Yarmush, M.L and Kohn, J. (1993) Copolymers of lysine and polyethylene glycols; a new family of functionalized drug carriers. Bioconj. Chem. 4, 54-62.
-
(1993)
Bioconj. Chem.
, vol.4
, pp. 54-62
-
-
Nathan, A.1
Zalipsky, S.2
Ertel, S.I.3
Agathos, S.N.4
Yarmush, M.L.5
Kohn, J.6
-
136
-
-
0028135121
-
Improved synthesis of adriamycin-conjugated poly(ethyloxide)-poly(aspartic acid) block copolymer and formation of unimodal micellar structure with controlled amount of physically entrapped adriamycin
-
Yokoyama, M., Okano, T., Sakurai, Y. and Kataoka, K. (1994) Improved synthesis of adriamycin-conjugated poly(ethyloxide)-poly(aspartic acid) block copolymer and formation of unimodal micellar structure with controlled amount of physically entrapped adriamycin. J. Control. Release 32, 269-277.
-
(1994)
J. Control. Release
, vol.32
, pp. 269-277
-
-
Yokoyama, M.1
Okano, T.2
Sakurai, Y.3
Kataoka, K.4
-
137
-
-
0028346185
-
Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly(ethylene oxide-aspartate) block copolymer-adriamycin conjugates
-
Kwon, G., Suwa, S., Yokoyama, M., Okano, T., Sakurai, Y. and Kataoka, K. (1994) Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly(ethylene oxide-aspartate) block copolymer-adriamycin conjugates. J. Control. Release 29, 17-23.
-
(1994)
J. Control. Release
, vol.29
, pp. 17-23
-
-
Kwon, G.1
Suwa, S.2
Yokoyama, M.3
Okano, T.4
Sakurai, Y.5
Kataoka, K.6
-
138
-
-
0025015189
-
Polymer micelles as novel drug carrier: Adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer
-
Yokoyama, M., Miyauchi, M., Yamada, N., Okano, T., Sakurai, Y., Kataoka, K. and Inoue, S. (1990) Polymer micelles as novel drug carrier: adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer. J. Control. Release 11, 269-278.
-
(1990)
J. Control. Release
, vol.11
, pp. 269-278
-
-
Yokoyama, M.1
Miyauchi, M.2
Yamada, N.3
Okano, T.4
Sakurai, Y.5
Kataoka, K.6
Inoue, S.7
-
140
-
-
0028337034
-
Distribution and tissue uptake of poly(ethylene glycol) with different molecular weight after intravenous administration into rats
-
Yamoka, T., Tabata, Y. and Ikada, Y. (1984) Distribution and tissue uptake of poly(ethylene glycol) with different molecular weight after intravenous administration into rats. J. Pharm. Sci. 83, 601-606.
-
(1984)
J. Pharm. Sci.
, vol.83
, pp. 601-606
-
-
Yamoka, T.1
Tabata, Y.2
Ikada, Y.3
-
141
-
-
0001252124
-
Molecular design for missile drug: Synthesis of adriamycin conjugated with immunoglobulin G using poly(ethylene glycol)-block-poly(aspartic acid) as intermediate carrier
-
Yokoyama, M., Inoue, S., Kataoka, K., Yui, N., Okano, T. and Sakurai, Y. (1989) Molecular design for missile drug: synthesis of adriamycin conjugated with immunoglobulin G using poly(ethylene glycol)-block-poly(aspartic acid) as intermediate carrier. Makromol. Chem. 190, 2041-2054.
-
(1989)
Makromol. Chem.
, vol.190
, pp. 2041-2054
-
-
Yokoyama, M.1
Inoue, S.2
Kataoka, K.3
Yui, N.4
Okano, T.5
Sakurai, Y.6
-
142
-
-
0028152785
-
Specific drug delivery using PEG/ADR conjugate and PEG/ ADR/saccharide conjugate
-
Ohya, Y., Kuroda, H. and Ouchi, T. (1994) Specific drug delivery using PEG/ADR conjugate and PEG/ ADR/saccharide conjugate. Proc. Int. Symp. Control. Release Bioact. Mater. 21, 666-667.
-
(1994)
Proc. Int. Symp. Control. Release Bioact. Mater.
, vol.21
, pp. 666-667
-
-
Ohya, Y.1
Kuroda, H.2
Ouchi, T.3
-
143
-
-
6044249967
-
Paramagnetic metal complexes as water proton relaxation agents for NMR imaging: Theory and design
-
Lauffer, R.B. (1987) Paramagnetic metal complexes as water proton relaxation agents for NMR imaging: theory and design. Chem. Rev. 87, 901-927.
-
(1987)
Chem. Rev.
, vol.87
, pp. 901-927
-
-
Lauffer, R.B.1
-
144
-
-
0000537532
-
Targeting metal complexes
-
Parker, D. (1994) Targeting metal complexes. Chem. Br. 818-822.
-
(1994)
Chem. Br.
, pp. 818-822
-
-
Parker, D.1
-
145
-
-
0001611128
-
Contrast agents
-
D.D. Stark and W.G. Bradley (Eds), 2nd Edn, Mosby Year Book Inc., USA
-
Watson, A.D., Rocklage, S.M. and Carvlin, M.J. (1991) Contrast agents. In: D.D. Stark and W.G. Bradley (Eds), Magnetic Resonance Imaging, Vol. 1, 2nd Edn, Mosby Year Book Inc., USA, pp. 372-437.
-
(1991)
Magnetic Resonance Imaging
, vol.1
, pp. 372-437
-
-
Watson, A.D.1
Rocklage, S.M.2
Carvlin, M.J.3
-
146
-
-
0024592214
-
Perfluorooctylbromide: A new contrast agent for CT, sonography, and MR imaging
-
Mattrey, R.F. (1989) Perfluorooctylbromide: a new contrast agent for CT, sonography, and MR imaging. Am. J. Roentgenol. 152, 247-252.
-
(1989)
Am. J. Roentgenol.
, vol.152
, pp. 247-252
-
-
Mattrey, R.F.1
-
147
-
-
0023852534
-
Magnetsim: A primer and review
-
Saini, S., Frankel, R.B., Stark, D.D. and Ferruci, J.T. (1988) Magnetsim: a primer and review. Am. J. Roentgenol. 150, 735-743.
-
(1988)
Am. J. Roentgenol.
, vol.150
, pp. 735-743
-
-
Saini, S.1
Frankel, R.B.2
Stark, D.D.3
Ferruci, J.T.4
-
148
-
-
0020532305
-
Work in progress: Potential oral and intravenous paramagnetic NMR contrast agents
-
Runge, V.M., Stewart, R.G., Clanton, J.A., Jones, M.M., Lukehart, C.M., Partain, C.L. and James, A.E. (1983) Work in progress: potential oral and intravenous paramagnetic NMR contrast agents. Radiology 147, 788-791.
-
(1983)
Radiology
, vol.147
, pp. 788-791
-
-
Runge, V.M.1
Stewart, R.G.2
Clanton, J.A.3
Jones, M.M.4
Lukehart, C.M.5
Partain, C.L.6
James, A.E.7
-
149
-
-
0021132984
-
Intravascular contrast agents suitable for magnetic resonance imaging
-
Runge, V.M., Clanton, J.A., Herzer, W.A., Gibbs, S.J., Price, A.C., Partain, C.L. and James, A.E. (1984) Intravascular contrast agents suitable for magnetic resonance imaging. Radiology 153, 171-176.
-
(1984)
Radiology
, vol.153
, pp. 171-176
-
-
Runge, V.M.1
Clanton, J.A.2
Herzer, W.A.3
Gibbs, S.J.4
Price, A.C.5
Partain, C.L.6
James, A.E.7
-
150
-
-
0021175090
-
Pulsatile blood velocity in human arteries displayed by magnetic resonance imaging
-
Feinberg, D.A., Crooks, L., Hoenninger, J., Arakawa, M. and Watts, J. (1984) Pulsatile blood velocity in human arteries displayed by magnetic resonance imaging. Radiology 153, 177-180.
-
(1984)
Radiology
, vol.153
, pp. 177-180
-
-
Feinberg, D.A.1
Crooks, L.2
Hoenninger, J.3
Arakawa, M.4
Watts, J.5
-
151
-
-
0021242787
-
Contrast enhancement of magnetic resonance imaging by chromium EDTA: An experimental study
-
Runge, V.M., Foster, M.A., Clanton, J.A., Jones, M.M., Lukehart, C.M., Hutchinson, J.M.S., Mallard, J.R., Smith, F.W., Partain, C.L. and James, A.E. (1984) Contrast enhancement of magnetic resonance imaging by chromium EDTA: an experimental study. Radiology 152, 123-126.
-
(1984)
Radiology
, vol.152
, pp. 123-126
-
-
Runge, V.M.1
Foster, M.A.2
Clanton, J.A.3
Jones, M.M.4
Lukehart, C.M.5
Hutchinson, J.M.S.6
Mallard, J.R.7
Smith, F.W.8
Partain, C.L.9
James, A.E.10
-
152
-
-
0021359442
-
Contrast-enhanced NMR imaging: Animal studies using gadolinium-DTPA complexes
-
Brasch, R.C., Weinmann, H.-J. and Wesbey, G.E. (1984) Contrast-enhanced NMR imaging: animal studies using gadolinium-DTPA complexes. Am. J. Roentgenol. 142, 625-630.
-
(1984)
Am. J. Roentgenol.
, vol.142
, pp. 625-630
-
-
Brasch, R.C.1
Weinmann, H.-J.2
Wesbey, G.E.3
-
153
-
-
0021129983
-
Gadolinium-DTPA as a contrast agent in MRI: Initial clinical experience in 20 patients
-
Carr, D.H., Brown, J., Bydder, G.M., Steiner, R.E., Weinmann, H.-J., Speck, U., Hall, A.S. and Young, I.R. (1984) Gadolinium-DTPA as a contrast agent in MRI: initial clinical experience in 20 patients. Am. J. Roentgenol. 143, 215-224.
-
(1984)
Am. J. Roentgenol.
, vol.143
, pp. 215-224
-
-
Carr, D.H.1
Brown, J.2
Bydder, G.M.3
Steiner, R.E.4
Weinmann, H.-J.5
Speck, U.6
Hall, A.S.7
Young, I.R.8
-
154
-
-
0025271135
-
Gadolinium-enhanced MR angiography
-
Creasy, J.L., Price, R.R., Presbrey, T., Goins, D., Partain, C.L. and Kessler, R.M. (1990) Gadolinium-enhanced MR angiography. Radiology, 175, 280-283.
-
(1990)
Radiology
, vol.175
, pp. 280-283
-
-
Creasy, J.L.1
Price, R.R.2
Presbrey, T.3
Goins, D.4
Partain, C.L.5
Kessler, R.M.6
-
155
-
-
0023769761
-
Myocardial paramagnetic contrast agents for MR imaging
-
Brown, J.J. and Higgins, C.B. (1988) Myocardial paramagnetic contrast agents for MR imaging. Am. J. Roentgenol. 151, 865-872.
-
(1988)
Am. J. Roentgenol.
, vol.151
, pp. 865-872
-
-
Brown, J.J.1
Higgins, C.B.2
-
156
-
-
0025358762
-
Comparison of Gd-BOPTA with Gd-DTPA in MR imaging of rat liver
-
Pavone, P., Patrizio, G., Buoni, C., Tettamanti, E., Passariello, R., Musu, C., Tirone, P. and Felder, E. (1990) Comparison of Gd-BOPTA with Gd-DTPA in MR imaging of rat liver. Radiology 176, 61-64.
-
(1990)
Radiology
, vol.176
, pp. 61-64
-
-
Pavone, P.1
Patrizio, G.2
Buoni, C.3
Tettamanti, E.4
Passariello, R.5
Musu, C.6
Tirone, P.7
Felder, E.8
-
157
-
-
0025838385
-
Manganese-DPDP as a hepatobiliary contrast agent in the magnetic resonance imaging of liver tumours
-
Rummney, E., Ehrenheim, C., Gehl, H.B., Hamm, B., Laniado, M., Lodemann, K.P., Schmiedel, E., Steudel, A. and Vogl, T.G.(1991) Manganese-DPDP as a hepatobiliary contrast agent in the magnetic resonance imaging of liver tumours. Invest. Radiol. 26, s142-s145.
-
(1991)
Invest. Radiol.
, vol.26
-
-
Rummney, E.1
Ehrenheim, C.2
Gehl, H.B.3
Hamm, B.4
Laniado, M.5
Lodemann, K.P.6
Schmiedel, E.7
Steudel, A.8
Vogl, T.G.9
-
158
-
-
0025079838
-
Preclinical profile of Gd-BOPTA as a liver-specific mri contrast agent
-
Vittadini, G., Felder, E., Musu, C. and Tirone, P. (1990) Preclinical profile of Gd-BOPTA as a liver-specific MRI contrast agent. Invest. Radiol. 25, s59-s60.
-
(1990)
Invest. Radiol.
, vol.25
-
-
Vittadini, G.1
Felder, E.2
Musu, C.3
Tirone, P.4
-
159
-
-
0027818685
-
The uptake of manganese dipyridoxaldiphosphate by chemically induced hepatocellular carcinoma in rats
-
Ni, Y., Marchal, G., Zhang, X., Van Hecke, P., Michiels, J., Yu, J., Rummeny, E., Lodemann, K.-P. and Baert, A.L.(1993) The uptake of manganese dipyridoxaldiphosphate by chemically induced hepatocellular carcinoma in rats. Invest. Radiol. 28, 520-528.
-
(1993)
Invest. Radiol.
, vol.28
, pp. 520-528
-
-
Ni, Y.1
Marchal, G.2
Zhang, X.3
Van Hecke, P.4
Michiels, J.5
Yu, J.6
Rummeny, E.7
Lodemann, K.-P.8
Baert, A.L.9
-
160
-
-
0023849561
-
Gd-DOTA; charcterisation of a new paramagnetic complex
-
Bousequet, J.-C., Saini, S., Stark, D.D., Hahn, P.F., Nigam, M., Wittenberg, J. and Ferruci, J.T. (1988) Gd-DOTA; charcterisation of a new paramagnetic complex. Radiology 166, 693-698.
-
(1988)
Radiology
, vol.166
, pp. 693-698
-
-
Bousequet, J.-C.1
Saini, S.2
Stark, D.D.3
Hahn, P.F.4
Nigam, M.5
Wittenberg, J.6
Ferruci, J.T.7
-
161
-
-
0024337153
-
Photodynamic therapy-achievements and prospects
-
Ash, D. and Brown, S.B. (1989) Photodynamic therapy-achievements and prospects. Br. J. Cancer 60, 151-152.
-
(1989)
Br. J. Cancer
, vol.60
, pp. 151-152
-
-
Ash, D.1
Brown, S.B.2
-
162
-
-
0023197648
-
Studies on the mechanism of selective retention of porphyrins and metalloporphyrins by cancer cells
-
Megnin, F., Faustino, P.J., Lyon, R.C., Lelkes, P.I. and Cohen, J.S. (1987) Studies on the mechanism of selective retention of porphyrins and metalloporphyrins by cancer cells. Biochim. Biophys. Acta 929, 173-181.
-
(1987)
Biochim. Biophys. Acta
, vol.929
, pp. 173-181
-
-
Megnin, F.1
Faustino, P.J.2
Lyon, R.C.3
Lelkes, P.I.4
Cohen, J.S.5
-
163
-
-
0022588104
-
Metalloporphyrin contrast agents for magnetic resonance imaging of human tumours in mice
-
Patronas, N.J., Cohen, J.S., Knop, R.H., Dwyer, A.J., Colocher, D., Lundy, J., Mornex, F., Hambright, P., Sohn, M. and Myers, C.E. (1986) Metalloporphyrin contrast agents for magnetic resonance imaging of human tumours in mice. Cancer Treatment Rep. 70, 391-395.
-
(1986)
Cancer Treatment Rep.
, vol.70
, pp. 391-395
-
-
Patronas, N.J.1
Cohen, J.S.2
Knop, R.H.3
Dwyer, A.J.4
Colocher, D.5
Lundy, J.6
Mornex, F.7
Hambright, P.8
Sohn, M.9
Myers, C.E.10
-
164
-
-
0023741128
-
Metalloporphyrin enhancement of magnetic resonance imaging of human tumor xenografts in nude mice
-
Furmanski, P. and Longley, C. (1988) Metalloporphyrin enhancement of magnetic resonance imaging of human tumor xenografts in nude mice. Cancer Res. 48, 4604-4610.
-
(1988)
Cancer Res.
, vol.48
, pp. 4604-4610
-
-
Furmanski, P.1
Longley, C.2
-
165
-
-
0021323539
-
Paramagnetic metalloporphyrins as potential contrast agents in NMR imaging
-
Chen, C.-W., Cohen, J.S., Myers, C.E. and Sohn, M. (1984) Paramagnetic metalloporphyrins as potential contrast agents in NMR imaging. FEBS Lett. 168, 70-74.
-
(1984)
FEBS Lett.
, vol.168
, pp. 70-74
-
-
Chen, C.-W.1
Cohen, J.S.2
Myers, C.E.3
Sohn, M.4
-
166
-
-
0021956395
-
Manganese protoporphyrin IX. A potential intravenous paramagnetic NMR contrast agent: Preliminary communication
-
Jackson, L.S., Nelson, J,A., Case, T.A. and Burnham, B.F. (1985) Manganese protoporphyrin IX. A potential intravenous paramagnetic NMR contrast agent: preliminary communication. Invest. Radiol. 20, 226-229.
-
(1985)
Invest. Radiol.
, vol.20
, pp. 226-229
-
-
Jackson, L.S.1
Nelson, J.2
Case, T.A.3
Burnham, B.F.4
-
167
-
-
0026615828
-
Snapshot FLASH measurement of rat brain glioma: Kinetics of the tumor enhancing contrast agent manganese(III) tetraphenylporphyrin sulfonate
-
Hoehn-Berlage, M., Norris, D., Bockhorst, K., Ernestus, R.-I., Kloiber, O., Bonnekoh, P., Leibfritz, D. and Hossman, K.-A. (1992) Snapshot FLASH measurement of rat brain glioma: kinetics of the tumor enhancing contrast agent manganese(III) tetraphenylporphyrin sulfonate. Magn. Reson. Med. 27, 201-213.
-
(1992)
Magn. Reson. Med.
, vol.27
, pp. 201-213
-
-
Hoehn-Berlage, M.1
Norris, D.2
Bockhorst, K.3
Ernestus, R.-I.4
Kloiber, O.5
Bonnekoh, P.6
Leibfritz, D.7
Hossman, K.-A.8
-
169
-
-
0022350667
-
Pulse sequence optimization for MR imaging using a paramagnetic hepatobiliary contrast agent
-
Greif, W.L., Buxton, R.B., Lauffer, R.B., Saini, S., Stark, D.D., Wedeen, V.J., Rosen, B.R. and Brady, T.J. (1985) Pulse sequence optimization for MR imaging using a paramagnetic hepatobiliary contrast agent. Radiology 157, 461-466.
-
(1985)
Radiology
, vol.157
, pp. 461-466
-
-
Greif, W.L.1
Buxton, R.B.2
Lauffer, R.B.3
Saini, S.4
Stark, D.D.5
Wedeen, V.J.6
Rosen, B.R.7
Brady, T.J.8
-
170
-
-
0027355550
-
Tetra-p-aminophenylporphyrin conjugated with Gd-DTPA: Tumor specific contrast agent for MR imaging
-
Hindré, F., Le Plouzennec, M., De Certaines, J.D., Foultier, M.T., Patrice, T. and Simonneaux, G. (1993) Tetra-p-aminophenylporphyrin conjugated with Gd-DTPA: tumor specific contrast agent for MR imaging. J. Magn. Reson. Imaging 3, 59-65.
-
(1993)
J. Magn. Reson. Imaging
, vol.3
, pp. 59-65
-
-
Hindré, F.1
Le Plouzennec, M.2
De Certaines, J.D.3
Foultier, M.T.4
Patrice, T.5
Simonneaux, G.6
-
171
-
-
0022230851
-
Delineation of a transplanted malignant melanoma with indium-111-labeled porphyrin
-
Foster, N., Woo, D.V., Kaltovich, F., Emrich, J. and Ljungquist, C. (1985) Delineation of a transplanted malignant melanoma with indium-111-labeled porphyrin. J. Nucl. Med. 26, 756-760.
-
(1985)
J. Nucl. Med.
, vol.26
, pp. 756-760
-
-
Foster, N.1
Woo, D.V.2
Kaltovich, F.3
Emrich, J.4
Ljungquist, C.5
-
172
-
-
0027961622
-
Polymetallic macromolecules are potential contrast agents of improved efficiency
-
Cavagna. F., Luchinat, C., Scozzafava, A. and Xia, Z.(1994) Polymetallic macromolecules are potential contrast agents of improved efficiency. Magn. Reson. Med. 31, 58-60.
-
(1994)
Magn. Reson. Med.
, vol.31
, pp. 58-60
-
-
Cavagna, F.1
Luchinat, C.2
Scozzafava, A.3
Xia, Z.4
-
173
-
-
0025158194
-
Polyethylene glycol-ferrioxamine. A new magnetic resonance contrast agent
-
Von Schulthess, G.K., Duewell, S., Jenny, H.-B., Wüthrich, R. and Peter, H.H. (1990) Polyethylene glycol-ferrioxamine. A new magnetic resonance contrast agent. Invest. Radiol. 25, s48.
-
(1990)
Invest. Radiol.
, vol.25
-
-
Von Schulthess, G.K.1
Duewell, S.2
Jenny, H.-B.3
Wüthrich, R.4
Peter, H.H.5
-
174
-
-
0023122392
-
Comparison of the contrast enhancing properties of albumin-(Gd-DTPA) and Gd-DTPA at 2.OT
-
Schmiedl, U., Ogan, M., Paajanen, H., Marotti, M., Crooks, L.E., Brito, A.C. and Brasch, R.C. (1987) Comparison of the contrast enhancing properties of albumin-(Gd-DTPA) and Gd-DTPA at 2.OT. Radiology 162, 205-210.
-
(1987)
Radiology
, vol.162
, pp. 205-210
-
-
Schmiedl, U.1
Ogan, M.2
Paajanen, H.3
Marotti, M.4
Crooks, L.E.5
Brito, A.C.6
Brasch, R.C.7
-
175
-
-
0024490017
-
Acute myocardial ischaemia and reperfusion: MR imaging with albumin-Gd-DTPA
-
Schmiedl, U., Sievers, R.E., Brasch, R.C., Wolfe, C.L., Chew, W.M., Ogan, M.D., Engeseth, H., Lipton, M.J. and Moseley, M.E. (1989) Acute myocardial ischaemia and reperfusion: MR imaging with albumin-Gd-DTPA. Radiology 170, 351-356.
-
(1989)
Radiology
, vol.170
, pp. 351-356
-
-
Schmiedl, U.1
Sievers, R.E.2
Brasch, R.C.3
Wolfe, C.L.4
Chew, W.M.5
Ogan, M.D.6
Engeseth, H.7
Lipton, M.J.8
Moseley, M.E.9
-
176
-
-
0028007063
-
Dynamic contrast-enhanced MR imaging of the upper abdomen: Enhancment properties of gadobutrol, gadolinium-DTPA-polylysine and gadolinium-DTPA-cascade polymers
-
Adam, G., Neuerburg, J., Spüntrup, E., Mühler, A., Scherer, K. and Günther, R.W. (1994) Dynamic contrast-enhanced MR imaging of the upper abdomen: enhancment properties of gadobutrol, gadolinium-DTPA-polylysine and gadolinium-DTPA-cascade polymers. Magn. Reson. Med. 32, 622-628.
-
(1994)
Magn. Reson. Med.
, vol.32
, pp. 622-628
-
-
Adam, G.1
Neuerburg, J.2
Spüntrup, E.3
Mühler, A.4
Scherer, K.5
Günther, R.W.6
-
177
-
-
0025719624
-
Paramagnetic dextrans as magnetic resonance contrast agents
-
Meyer, D., Schaeffer, M., Bouillot, A., Beauté, S. and Chambon, C. (1991) Paramagnetic dextrans as magnetic resonance contrast agents. Invest. Radiol. 25, s50-s52.
-
(1991)
Invest. Radiol.
, vol.25
-
-
Meyer, D.1
Schaeffer, M.2
Bouillot, A.3
Beauté, S.4
Chambon, C.5
-
178
-
-
0025259293
-
Evaluation of Gd-DTPA-labeled dextran as an intramuscular MR contrast agent: Imaging characteristics in normal rat tissues
-
Wang, S.-C., Wikström, M.G., White, D.L., Klaveness, J., Holtz, R., Rongved, P., Moseley, M.E. and Brasch, R.C. (1990) Evaluation of Gd-DTPA-labeled dextran as an intramuscular MR contrast agent: imaging characteristics in normal rat tissues. Radiology 175, 483-488.
-
(1990)
Radiology
, vol.175
, pp. 483-488
-
-
Wang, S.-C.1
Wikström, M.G.2
White, D.L.3
Klaveness, J.4
Holtz, R.5
Rongved, P.6
Moseley, M.E.7
Brasch, R.C.8
-
179
-
-
0027957863
-
Dendrimer-based metal chelates: A new class of magnetic resonance imaging contrast agents
-
Wiener, B.C., Brechbiel, M.W., Brothers, H., Magin, R.L., Gansow, O.A., Tomalia, D.A. and Lauterbur, P,C. (1994) Dendrimer-based metal chelates: a new class of magnetic resonance imaging contrast agents. Magn. Reson. Med. 31, 1-8.
-
(1994)
Magn. Reson. Med.
, vol.31
, pp. 1-8
-
-
Wiener, B.C.1
Brechbiel, M.W.2
Brothers, H.3
Magin, R.L.4
Gansow, O.A.5
Tomalia, D.A.6
Lauterbur, P.7
-
180
-
-
0025789917
-
40
-
40. Invest. Radiol. 26, s42-s45.
-
(1991)
Invest. Radiol.
, vol.26
-
-
Brasch, R.C.1
Berthezene, Y.2
Vexler, V.S.3
Moseley, M.4
Clément, O.5
Muehler, A.6
Price, D.7
Jerome, H.8
-
181
-
-
0025031142
-
Synthesis and characterisation of conjugates of poly(α-amino acids) and manganese(III) protoporphyrin IX as relaxaton enhancement agents for MRI
-
1990
-
Spaltro, S.M. and Foster, N. (1990) Synthesis and characterisation of conjugates of poly(α-amino acids) and manganese(III) protoporphyrin IX as relaxaton enhancement agents for MRI. J. Appl. Polym. Sci., 1990, 41, 1235-1249.
-
(1990)
J. Appl. Polym. Sci.
, vol.41
, pp. 1235-1249
-
-
Spaltro, S.M.1
Foster, N.2
-
182
-
-
0025256638
-
Relaxation enhancement of water protons by manganese III porphyrins: Influence of porphyrin aggregation
-
Kellar, K.E., Spaltro, S.M. and Foster, N. (1990) Relaxation enhancement of water protons by manganese III porphyrins: influence of porphyrin aggregation. Macromolecules 23, 428-431.
-
(1990)
Macromolecules
, vol.23
, pp. 428-431
-
-
Kellar, K.E.1
Spaltro, S.M.2
Foster, N.3
-
183
-
-
0024524599
-
Liposomal Gd-DTPA: Preparation and charcterisation of relaxivity
-
Tilcock, C., Unger, E., Cullis, P. and MacDougall, P. (1989) Liposomal Gd-DTPA: preparation and charcterisation of relaxivity. Radiology 171, 77-80.
-
(1989)
Radiology
, vol.171
, pp. 77-80
-
-
Tilcock, C.1
Unger, E.2
Cullis, P.3
MacDougall, P.4
-
184
-
-
0024561823
-
The role of liposomes in diagnostic imaging
-
Seltzer, S.E.(1989) The role of liposomes in diagnostic imaging. Radiology 171, 19-21.
-
(1989)
Radiology
, vol.171
, pp. 19-21
-
-
Seltzer, S.E.1
-
185
-
-
0025237262
-
The effect of lipid composition on the relaxivity of Gd-GTPA entrapped in lipid vesicles of defined size
-
Tilcock, C., MacDougall, P., Unger, E., Cardenas, D. and Fajardo, L. (1990) The effect of lipid composition on the relaxivity of Gd-GTPA entrapped in lipid vesicles of defined size. Biochim. Biophys. Acta 1022, 181-186.
-
(1990)
Biochim. Biophys. Acta
, vol.1022
, pp. 181-186
-
-
Tilcock, C.1
Macdougall, P.2
Unger, E.3
Cardenas, D.4
Fajardo, L.5
-
186
-
-
0025071116
-
Paramagnetic liposomes as magnetic resonance contrast agents
-
Unger, E., Tilcock, C., Ahkong, Q.F. and Fritz, T. (1990) Paramagnetic liposomes as magnetic resonance contrast agents. Invest. Radiol. 25, s65-s66.
-
(1990)
Invest. Radiol.
, vol.25
-
-
Unger, E.1
Tilcock, C.2
Ahkong, Q.F.3
Fritz, T.4
-
187
-
-
0024602061
-
Hepatic metastases: Liposomal Gd-DTPA-enhanced imaging
-
Unger, E., Winokur, T., MacDougall, P., Rosenblum, J., Clair, M., Gatenby, R. and Tilcock, C. (1989) Hepatic metastases: liposomal Gd-DTPA-enhanced imaging. Radiology 171, 81-85.
-
(1989)
Radiology
, vol.171
, pp. 81-85
-
-
Unger, E.1
Winokur, T.2
Macdougall, P.3
Rosenblum, J.4
Clair, M.5
Gatenby, R.6
Tilcock, C.7
-
188
-
-
0023149760
-
Gadolinium-labeled liposomes: Targeted MR contrast agents for the liver and spleen
-
Kabalka, G., Buonocore, E., Hubner, K., Moss, T., Norley, N. and Huang, L. (1987) Gadolinium-labeled liposomes: targeted MR contrast agents for the liver and spleen. Radiology 163, 255-258.
-
(1987)
Radiology
, vol.163
, pp. 255-258
-
-
Kabalka, G.1
Buonocore, E.2
Hubner, K.3
Moss, T.4
Norley, N.5
Huang, L.6
-
189
-
-
0025360715
-
A pharmacokinetic and MRI study of unilamellar gadolinium-, manganese, and iron-DTPA-stearate liposomes as organspecific contrast agents
-
Schwendener, R.A., Wüthrich, R., Duewell, S., Wehrli, E. and Von Schulthess, G.K. (1990) A pharmacokinetic and MRI study of unilamellar gadolinium-, manganese, and iron-DTPA-stearate liposomes as organspecific contrast agents. Invest. Radiol. 25, 922-932.
-
(1990)
Invest. Radiol.
, vol.25
, pp. 922-932
-
-
Schwendener, R.A.1
Wüthrich, R.2
Duewell, S.3
Wehrli, E.4
Von Schulthess, G.K.5
-
190
-
-
0026187693
-
Cross-linked degradable starch microspheres as carriers of paramagnetic contrast agents for magnetic resonance imaging: Synthesis, degradation and relaxation properties
-
Rongved, P., Lindberg, B. and Klaveness, J. (1991) Cross-linked degradable starch microspheres as carriers of paramagnetic contrast agents for magnetic resonance imaging: synthesis, degradation and relaxation properties. Carbohydr. Res. 214, 325-330.
-
(1991)
Carbohydr. Res.
, vol.214
, pp. 325-330
-
-
Rongved, P.1
Lindberg, B.2
Klaveness, J.3
-
191
-
-
0020534380
-
Work in progress: Nuclear magnetic resonance study of a paramagnetic nitroxide contrast agent for enhancement of renal structures in experimental animals
-
1983
-
Brasch, R.C., London, D.A., Wesbey, G.E., Tozer, T. N., Nitecki, D.E., Williams, D.W., Doemeny, J., Tuck, L.D. and Lalemand, D.P. (1983) Work in progress: nuclear magnetic resonance study of a paramagnetic nitroxide contrast agent for enhancement of renal structures in experimental animals. Radiology, 1983, 147, 773-779.
-
(1983)
Radiology
, vol.147
, pp. 773-779
-
-
Brasch, R.C.1
London, D.A.2
Wesbey, G.E.3
Tozer, T.N.4
Nitecki, D.E.5
Williams, D.W.6
Doemeny, J.7
Tuck, L.D.8
Lalemand, D.P.9
-
192
-
-
0023155627
-
Ferrite particles: A supraparamagnetic MR contrast agent for the reticuloendothelial system
-
Saini, S., Stark, D.D., Hahn, P.F., Wittenberg, J., Brady, T.J. and Ferruci, J.T. (1987) Ferrite particles: a supraparamagnetic MR contrast agent for the reticuloendothelial system. Radiology 162, 211-216.
-
(1987)
Radiology
, vol.162
, pp. 211-216
-
-
Saini, S.1
Stark, D.D.2
Hahn, P.F.3
Wittenberg, J.4
Brady, T.J.5
Ferruci, J.T.6
-
193
-
-
0023112330
-
Ferrite particles: A supraparamagnetic MR contrast agent for enhanced detection of liver carcinoma
-
Saini, S., Stark, D.D., Hahn. P.F., Bousquet, J.-C., Introcasso, J., Wittenberg, J., Brady, T.J. and Ferrucci, J.T. (1987) Ferrite particles: a supraparamagnetic MR contrast agent for enhanced detection of liver carcinoma. Radiology 162, 217-222.
-
(1987)
Radiology
, vol.162
, pp. 217-222
-
-
Saini, S.1
Stark, D.D.2
Hahn, P.F.3
Bousquet, J.-C.4
Introcasso, J.5
Wittenberg, J.6
Brady, T.J.7
Ferrucci, J.T.8
-
194
-
-
0025017450
-
Clinical applications of supraparamagnetic iron oxide to MR imaging of tissue perfusion in vascular liver tumors
-
Hahn, P.F., Stark, D.D., Weissleder, R., Elizondo, G., Saini, S. and Ferruci, J.T. (1990) Clinical applications of supraparamagnetic iron oxide to MR imaging of tissue perfusion in vascular liver tumors. Radiology 174, 361-366.
-
(1990)
Radiology
, vol.174
, pp. 361-366
-
-
Hahn, P.F.1
Stark, D.D.2
Weissleder, R.3
Elizondo, G.4
Saini, S.5
Ferruci, J.T.6
-
195
-
-
0023801420
-
Supraparamagnetic iron oxide: Clinical applications as s contrast agent for MR imaging of the liver
-
Stark, D.D., Weissleder, R., Eloizondo, G., Hahn, P.F., Saini, S., Todd, L.E., Wittenberg, J. and Ferruci. J.T. (1988) Supraparamagnetic iron oxide: clinical applications as s contrast agent for MR imaging of the liver. Radiology 168, 297-301.
-
(1988)
Radiology
, vol.168
, pp. 297-301
-
-
Stark, D.D.1
Weissleder, R.2
Eloizondo, G.3
Hahn, P.F.4
Saini, S.5
Todd, L.E.6
Wittenberg, J.7
Ferruci, J.T.8
-
196
-
-
0025392476
-
Assessment of a supraparamagnetic iron oxide (AMI-25) as a brain contrast agent
-
Kent, T.A., Quast, M.J., Kaplan, B.J., Lifsey, R.S. and Eisenberg, H.M. (1990) Assessment of a supraparamagnetic iron oxide (AMI-25) as a brain contrast agent. Magn. Reson. Med. 13, 434-443.
-
(1990)
Magn. Reson. Med.
, vol.13
, pp. 434-443
-
-
Kent, T.A.1
Quast, M.J.2
Kaplan, B.J.3
Lifsey, R.S.4
Eisenberg, H.M.5
-
197
-
-
0025295512
-
Cardiovascular MR imaging with iron oxide particles: Utility of a supraparamagnetic contrast agent and the role of diffusion in signal loss
-
Rozenman, Y., Zou, X. and Kantor, H.L. (1990) Cardiovascular MR imaging with iron oxide particles: utility of a supraparamagnetic contrast agent and the role of diffusion in signal loss. Radiology 175, 655-659.
-
(1990)
Radiology
, vol.175
, pp. 655-659
-
-
Rozenman, Y.1
Zou, X.2
Kantor, H.L.3
-
198
-
-
0026500624
-
Dextran-magnetite particles: Contrast enhanced MRI of blood-brain barrier disruption in a rat model
-
Bulte, J.W.M., De Jonge, M.W.A., Kamman, R.L., Go, K.G., Zuiderveen, F., Blaauw, B., Oosterbaan, J.A., The, T. H. and De Leij, L. (1992) Dextran-magnetite particles: contrast enhanced MRI of blood-brain barrier disruption in a rat model. Magn. Reson. Med. 23, 215-223.
-
(1992)
Magn. Reson. Med.
, vol.23
, pp. 215-223
-
-
Bulte, J.W.M.1
De Jonge, M.W.A.2
Kamman, R.L.3
Go, K.G.4
Zuiderveen, F.5
Blaauw, B.6
Oosterbaan, J.A.7
The, T.H.8
De Leij, L.9
-
199
-
-
0023143389
-
Magnetite albumin microspheres: A new MR contrast material
-
Widder, D.J., Greif, W.L., Widder, K.J., Edelmam, R.R. and Brady, T.J. (1987) Magnetite albumin microspheres: a new MR contrast material. Am. J. Roentgenol. 148, 399-404.
-
(1987)
Am. J. Roentgenol.
, vol.148
, pp. 399-404
-
-
Widder, D.J.1
Greif, W.L.2
Widder, K.J.3
Edelmam, R.R.4
Brady, T.J.5
-
200
-
-
0025257041
-
Ultra-small supraparamagnetic iron oxide: Characterisation of a new class of agents for MR imaging
-
Weissleder, R., Elizondo, G., Wittenberg, J., Rabito, C.A., Bengele, H.H. and Josephson, L. (1990) Ultra-small supraparamagnetic iron oxide: characterisation of a new class of agents for MR imaging. Radiology 175, 489-493.
-
(1990)
Radiology
, vol.175
, pp. 489-493
-
-
Weissleder, R.1
Elizondo, G.2
Wittenberg, J.3
Rabito, C.A.4
Bengele, H.H.5
Josephson, L.6
-
201
-
-
0025253906
-
Ultrasmall supraparamagnetic iron oxide: An intravenous contrast agent for assessing lymph nodes with MR imaging
-
Weissleder, R., Elizondo, G., Wittenberg, J., Lee, A. S., Josephson, L. and Brady, T.J. (1990) Ultrasmall supraparamagnetic iron oxide: an intravenous contrast agent for assessing lymph nodes with MR imaging. Radiology 175, 494-498.
-
(1990)
Radiology
, vol.175
, pp. 494-498
-
-
Weissleder, R.1
Elizondo, G.2
Wittenberg, J.3
Lee, A.S.4
Josephson, L.5
Brady, T.J.6
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