Analogues of 10-deazaaminopterin and 5-alkyl-5,10-dideazaaminopterin with the 4-substituted 1-naphthoyl group in the place of 4-substituted benzoyl

Journal of Medicinal Chemistry

Volumn 39, Issue 2, 1996, Pages 614-618

  Piper, James R ^a   Ramamurthy, Balakrishnan ^a   Johnson, Cheryl A ^a   Otter, Glenys M ^b   Sirotnak, Francis M ^b  

^a SOUTHERN RESEARCH INSTITUTE   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

10 DEAZAAMINOPTERIN; 5,10 DIDEAZAAMINOPTERIN; AMINOPTERIN DERIVATIVE; BENZENE DERIVATIVE; EDATREXATE; METHOTREXATE; N [4 [2 (2,4 DIAMINO 6 PTERIDINYL)ETHYL] 1 NAPHTHOYL]GLUTAMIC ACID; NAPHTHALENE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; CANCER INHIBITION; CONTROLLED STUDY; DRUG CLEARANCE; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGENATION; MOUSE; NONHUMAN; TUMOR CELL LINE;

ADENOCARCINOMA; ALKYLATION; AMINOPTERIN; ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; TUMOR CELLS, CULTURED;

EID: 0030031241     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9506940     Document Type: Article

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