Reasons for the emergence of antibiotic resistance

American Journal of the Medical Sciences

Volumn 311, Issue 1, 1996, Pages 9-16

  Tenover, Fred C ^a,b,c   McGowan Jr , John E ^b  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b EMORY UNIVERSITY   (United States)

^c NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES   (United States)

Author keywords

Antimicrobial resistance; Emerging infections; Resistance mechanisms

Indexed keywords

ANTIBIOTIC AGENT; CHLORAMPHENICOL; COTRIMOXAZOLE; PENICILLIN G; TETRACYCLINE;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENETICS; BACTERIUM MUTANT; DRUG USE; GENE TRANSFER; NONHUMAN;

EID: 0030030708     PISSN: 00029629     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000441-199601000-00003     Document Type: Article

References (82)

1. Institute of Medicine. Emerging infections - Microbial threats to health in the United States. Washington: National Academy Press; 1992.
2. Goldmann DA, Weinstein RA, Wenzel RP, Martone WJ, Duma R, Tablan OC, et al. Strategies to prevent and control the emergence and spread of antibiotic-resistant microorganisms in hospitals - A challenge to hospital leadership. JAMA. 1995. In press.
3. American Society for Microbiology. Report of the ASM Task Force on Antibiotic Resistance. Antimicrob Agents Chemother. 1995;39(suppl 5):1-23.
4. McGowan JE, Jr. Cost and benefit in perioperative antimicrobial prophylaxis - Methods for economic analysis. Rev Infect Dis. 1991;13(suppl 10):S879-89.
5. Murray BE. Can antibiotic resistance be controlled? N Engl J Med. 1994;330:1229-30.
6. Coronado VG, Edwards JR, Culver DH, Gaynes RP, National Nosocomial Infections Surveillance System. Ciprofloxacin resistance among nosocomial Pseudomonas aeruginosa and Staphylococcus aureus in the United States. Infect Control Hosp Epidemiol. 1995;16:71-5.
7. Tomasz A. Multiple-antibiotic-resistant pathogenic bacteria. A report on the Rockefeller University workshop. N Engl J Med. 1994;330:1247-51.
8. Meyer KS, Urban C, Eagan JA, Berger BJ, Rahal JJ. Nosocomial outbreak of Klebsiella infection resistant to late-generation cephalosporins. Ann Intern Med. 1993;119:353-8.
9. Berkelman RL. Emerging infectious diseases in the United States, 1993. J Infect Dis. 1994;170:272-7.
10. Bergogne-Berezin E, Decre D, Joly-Guillou ML. Opportunistic multiply resistant bacterial infections - Their treatment and prevention. J Antimicrob Chemother. 1993;32(suppl A):39-47.
11. Cohen ML. Epidemiology of drug resistance: Implications for a post-antimicrobial era. Science. 1992;257:1050-5.
12. Greenwood D. Preserving the miracle of antibiotics. Lancet. 1995;345:1371.
13. McGowan JE Jr. Abrupt changes in antibiotic resistance. J Hosp Infect. 1991;17(suppl A):202-10.
14. Mayer KH, Opal SM. Unusual nosocomial pathogens. Infect Dis Clin North Am. 1989;3:883-99.
15. Levy SB. Confronting multidrug resistance - A role for each of us. JAMA. 1993;269:1840-2.
16. Abraham EP. An enzyme from bacteria able to destroy penicillin. Nature. 1940;146:837-9.
17. Kirby WMM. Extraction of a highly potent penicillin inactivator from penicillin resistant staphylococci. Science. 1944;99:452-5.
18. Tenover FC. Novel and emerging mechanisms of antimicrobial resistance in nosocomial pathogens. Am J Med. 1991;91(suppl B):76S-81S.
19. Neu HC. The crisis in antibiotic resistance. Science. 1992;237: 1064-73.
20. Murray BE. New aspects of antimicrobial resistance and the resulting therapeutic dilemmas. J Infect Dis. 1991;163:1185-94.
21. McGowan JE Jr. Antibiotic resistance in hospital bacteria: Current patterns, modes for appearance or spread, and economic impact. Reviews in Medical Microbiology. 1991;2:161-9.
22. McGowan JE Jr. Antibiotic resistance in hospital bacteria: I. The importance of studying modes of appearance or spread. APUA Newsletter. 1992;10:4-5.
23. McGowan JE Jr. Antibiotic resistance in hospital bacteria: II. Impact of different modes on hospital infection control methods. APUA Newsletter. 1992;10:4-5.
24. McGowan JE Jr, Metchock B. Infection control epidemiology and clinical microbiology. In: Murray PR, Baron EJ, Pfaller MA, Tenover FC, Yolken RH, eds. Manual of Clinical Microbiology, 6th ed. Washington: American Society for Microbiology; 1995:182-9.
25. Anderson RL. Iodophor antiseptics: Intrinsic microbial contamination with resistant bacteria. Infect Control Hosp Epidemiol. 1989;10:443-6.
26. Lester SC, del Pilar Pla M, Wang F, Schael IP, Jiang H, O'Brien TF. The carriage of Escherichia coli resistant to antimicrobial agents by healthy children in Boston, in Caracas, Venezuela, and in Qin Pu, China. N Engl J Med. 1990;323:285-9.
27. Boyce JM. Methicillin-resistant Staphylococcus aureus: Detection, epidemiology, and control measures. Infect Dis Clin North Am. 1989;3:901-13.
28. Hartstein AH, Denny MA, Morthland VH, LeMonte AM, Pfaller MA. Control of methicillin-resistant Staphylococcus aureus in a hospital and an intensive care unit. Infect Control Hosp Epidemiol. 1995;16:405-11.
29. Layton MC, Hierholzer WJ Jr, Patterson JE. The evolving epidemiology of methicillin-resistant Staphylococcus aureus at a university hospital. Infect Control Hosp Epidemiol. 1995;18:12-7.
30. Rosenberg J. Methicillin-resistant Staphylococcus aureus (MRSA) in the community: Who's watching? Lancet. 1995;346: 132-3.
31. Sanders CC, Wiedemann B. Conference summary. Rev Infect Dis. 1988;10:679-80.
32. Weinstein RA, Kabins SA. Strategies for prevention and control of multiple drug-resistant nosocomial infections. Am J Med. 1991;70:449-54.
33. Medeiros AA. Nosocomial outbreaks of multiresistant bacteria: Extended-spectrum beta-lactamases have arrived in North America. Ann Intern Med. 1993;119:428-30.
34. DeFlaun MF, Levy SB. Genes and their varied hosts. In: Levy SB, Miller RV, eds. Gene transfer in the environment. New York: McGraw Hill Publishing Co; 1991:1-32.
35. Arthur M, Andremont A, Courvalin P. Distribution of erythromycin esterase and rRNA methylase genes in members of the family Enterobacteriaceae highly resistant to erythromycin. Antimicrob Agents Chemother. 1987;31:404-9.
36. Trieu-Cuot P, Gerbaud G, Lambert T, Courvalin P. In vivo transfer of genetic information between gram-negative and gram-positive bacteria. EMBO J. 1985;4:3583-7.
37. Murray BE, Mederski-Samoraj B, Foster SK, Brunton JL, Harford P. In vitro studies of plasmid-mediated penicillinase from Streptococcus faecalis suggest a staphylococcal origin. J Clin Invest. 1986;77:289-93.
38. Collatz E, Carlier C, Courvalin P. The chromosomal 3′5″-aminoglycoside phosphotransferase in Streptococcus pneumoniae is closely related to its plasmid-coded homologs in Streptococcus faecalis and Staphylococcus aureus. J Bacteriol. 1983;156:1373-7.
39. Noble WC, Virani Z, Cree RGA. Co-transfer of vancomycin and other resistance genes from Enterococcus faecalis NCTC 12201 to Staphylococcus aureus. FEMS Microbiol Lett. 1992;93: 195-8.
40. Ries AA, Wells JG, Olivola D, Ntakibirora M, Nyandwi S, Ntibakivayo M, et al. Epidemic Shigella dysentariae type 1 in Burundi: Pan-resistance and implications for prevention. J Infect Dis. 1995;169:1035-41.
41. Weber JT, Mintz ED, Canizares R, Semiglia A, Gomez I, Sempertegui R, et al. Epidemic cholera in Ecuador: Multidrug-resistance and transmission by water and seafood. Epidemiol Infect. 1994;112:1-11.
42. Roy C, Segura C, Tirado M, Reig R, Hermida M, Teruel D, et al. Frequency of plasmid-determined beta-lactamases in 680 consecutively isolated strains of Enterobacteriaceae. Eur J Clin Microbiol. 1985;4:146-7.
43. Phillipon A, Labia R, Jacoby G. Extended-spectrum β-lactamases. Antimicrob Agents Chemother. 1989;33:1131-6.
44. Jacoby GA, Medeiros AA. More extended spectrum beta-lactamases. Antimicrob Agents Chemother. 1991;35:1697-1704.
45. Sougakoff W, Goussard S, Gerbaud G, Courvalin P. Plasmid-mediated resistance to third generation cephalosporins caused by point mutations in TEM-type penicillinase genes. Rev Infect Dis. 1988;10:879-84.
46. Smith CE, Tilman S, Howell AW, Longfield RN, Jorgensen JH. Failure of ceftazidime-amikacin therapy for bacteremia and meningitis due to Klebsiella pneumoniae producing an extended spectrum β-lactamase. Antimicrob Agents Chemother. 1990;34:1290-3.
47. Sanders WE Jr, Sanders CC. Inducible beta-lactamases: Clinical and epidemiologic implications for use of newer cephalosporins. Rev Infect Dis. 1988;10:830-8.
48. Chow JW, Fine MJ, Shlaes DM, Quinn JP, Hooper DC, Johnson MP, et al. Enterobacter bacteremia: Clinical features and emergence of antibiotic resistance during therapy. Ann Intern Med. 1991;115:585-90.
49. Parry MF. Epidemiology and mechanisms of antimicrobial resistance. Am J Infect Control. 1989;17:286-94.
50. McGowan JE Jr. Antimicrobial resistance in hospital organisms and its relation to antibiotic use. Rev Infect Dis. 1983;5: 1033-48.
51. Chetchotisakd P, Phelps CL, Hartstein AT. Assessment of bacterial cross-transmission as a cause of infections in patients in intensive care units. Clin Infect Dis. 1994;18:929-37.
52. McGowan JE Jr. New laboratory techniques for hospital infection control. Am J Med. 1991;91(suppl 3B):245S-51S.
53. Hadorn K, Lenz W, Kayser FH, Shalit I, Krasemann C. Use of a ribosomal RNA gene probe for the epidemiological study of methicillin and ciprofloxacin resistant Staphylococcus aureus. Eur J Clin Microbiol. 1990;9:649-53.
54. Williams RJ. Epidemiology of antibiotic resistance in Gram-negative bacteria. J Hosp Infect. 1988;11(suppl A):130-4.
55. Skolnick A. New insights into how bacteria develop antibiotic resistance. JAMA. 1991;265:14-6.
56. Lambert HP. Clinical impact of drug resistance. J Hosp Infect. 1988;11(suppl A):135-41.
57. Edlin BR, Tokars JI, Grieco MH, Crawford JT, Williams J, Sordillo EM, et al. An outbreak of multidrug resistant tuberculosis among hospitalized patients with acquired immunodeficiency syndrome. N Engl J Med. 1992;326:1514-21.
58. McGowan JE Jr, Metchock BG. Penicillin-resistant pneumococci - An emerging threat to successful therapy. J Hosp Infect. 1995;30(suppl):472-82.
59. Klugman K. Pneumococcal resistance to antibiotics. Clin Microbiol Rev. 1990;3:171-96.
60. Reichler MR, Allphin AA, Breiman RF, Schreiber JR, Arnold JE, McDougal LK, et al. The spread of multiply resistant Streptococcus pneumoniae at a day care center in Ohio. J Infect Dis. 1992;166:1346-53.
61. Hoffman J, Cetron MS, Farley MM, Baughman WS, Facklam RR, Elliott JA, et al. The prevalence of drug-resistant Streptococcus pneumoniae in Atlanta. N Engl J Med. 1995;333:481-6.
62. Centers for Disease Control and Prevention. Drug-resistant Streptococcus pneumoniae - Kentucky and Tennessee, 1993. JAMA. 1994;271:421-2.
63. Munoz R, Coffey TJ, Daniels M, Dowson CG, Laible G, Casal J, et al. Intercontinental spread of a multiresistant clone of serotype 23F Streptococcus pneumoniae. J Infect Dis. 1991;164: 302-6.
64. McDougal LK, Facklam R, Reeves M, Hunter S, Swenson JM, Hill BC, et al. Analysis of multiply antimicrobial-resistant isolates of Streptococcus pneumoniae from the United States. Antimicrob Agents Chemother. 1992;36:2176-84.
65. Klugman KP, Coffey TJ, Smith A, Wasas A, Meyers M, Spratt BG. Cluster of an erythromycin-resistant variant of Spanish multiply resistant 23F clone of Streptococcus pneumoniae in South Africa. Eur J Clin Microbiol Infect Dis. 1994;13: 171-4.
66. McDougal LK, Tenover FC. Analysis of penicillin and cephalosporin-resistant Streptococcus pneumoniae isolates: Relatedness of U.S. isolates and comparison of penicillin binding protein (PBP) affinities. Program and Abstracts of the 33rd Interscience Conference on Antimicrobial Agents and Chemotherapy, October 17-20, 1993. New Orleans: American Society for Microbiology; 1993:Abstract 04, p. 138.
67. Sloas MM, Barrett FF, Chesney PJ, English BK, Hill BC, Tenover FC, et al. Cephalosporin treatment failure in penicillin- and cephalosporin-resistant Streptococcus pneumoniae meningitis. Pediatr Infect Dis J. 1992;11:662-6.
68. McGowan JE Jr, Hall EC, Parrott PL. Antimicrobial susceptibility in gram-negative bacteremia: Are nosocomial isolates really more resistant? Antimicrob Agents Chemother. 1989;33: 1855-9.
69. Cohen ML, Tauxe RV. Drug-resistant Salmonella in the United States: An epidemiologic perspective. Science. 1986;234:964-9.
70. Endtz HP, Ruijs GJ, van Klingeren B, Jansen WH, van der Reyden T, Mouton RP. Quinolone resistance in campylobacters isolated from man and poultry following the introduction of fluoroquinolones in veterinary medicine. J Antimicrob Chemother. 1991;27:199-208.
71. Mirelis B, Miro E, Navarro F, Ogalla CA, Bonal J, Prats G. Increased resistance to quinolone in Catalonia, Spain. Diagn Microbiol Infect Dis. 1993;16:137-9.
72. Rautelin R, Renkonen O-V, Kusunen TU. Emergence of fluoroquinolone resistance in Campylobacter jejuni and Campylobacter coli in subjects from Finland. Antimicrob Agents Chemother. 1991;35:2065-9.
73. Hoiby N. Epidemiologic aspects on antibiotic resistance. Microbial Drug Resistance. 1995;1:137-42.
74. Gaynes R. Antibiotic resistance in ICUs: A multifaceted problem requiring a multifaceted solution. Infect Control Hosp Epidemiol. 1995;16:328-30.
75. Patterson JE, Sanchez RO, Hernandez J, Grota P, Rose KA. Special organism isolation: Attempting to bridge the gap. Infect Control Hosp Epidemiol. 1994;15:335-8.
76. Flynn D, Weinstein RA, Kabins SA. Infections with gram-negative bacilli in a cardiac surgery intensive care unit: The relative role of enterobacter. J Hosp Infect. 1988;11(suppl A): 367-73.
77. Kunin CM. Resistance to antimicrobial drugs - A worldwide calamity. Ann Intern Med. 1993;118:557-61.
78. Reagan DR, Doebbeling BN, Pfaller MA, Sheetz CT, Houston AK, Hollis RJ, et al. Elimination of coincident Staphylococcus aureus nasal and hand carriage with intranasal application of mupirocin calcium ointment. Ann Intern Med. 1991;114:101-6.
79. Warren JW. Providencia stuartii: A common cause of anti biotic-resistant bacteriuria in patients with long-term indwelling catheters. Rev Infect Dis. 1986;8:61-7.
80. Brun-Buisson C, Legrand P, Rauss A, Richard C, Montravers F, Besbes M, et al. Intestinal decontamination for control of nosocomial multiresistant gram-negative bacilli. Ann Intern Med. 1989;110:873-81.
81. Weiner J, Itokazu G, Nathan C, Kabins SA, Weinstein RA. A randomized, double-blind placebo-controlled trial of selective decontamination in a medical-surgical intensive care unit. Clin Infect Dis. 1995;20:861-7.
82. Rhinehart E, Smith NE, Wennersten C, Gorss E, Freeman J, Eliopoulos GM, et al. Rapid dissemination of β-lactamase-producing, aminoglycoside-resistant Enterococcus faecalis among patients and staff on an infant-toddler surgical ward. N Engl J Med. 1990;323:1814-8.