메뉴 건너뛰기




Volumn 39, Issue 2, 1996, Pages 359-370

Synthesis and quantitative structure-activity relationship of a novel series of small conductance Ca2+-activated K+ channel blockers related to dequalinium

Author keywords

[No Author keywords available]

Indexed keywords

DEQUALINIUM; POTASSIUM CHANNEL BLOCKING AGENT; QUINOLINE DERIVATIVE;

EID: 0030030509     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950520i     Document Type: Article
Times cited : (40)

References (47)
  • 1
    • 0000631480 scopus 로고
    • Cook, N. S., Ed.; Ellis Horwood Ltd.: Chichester
    • Haylett, D. G.; Jenkinson, D. H. In Potassium Channels; Cook, N. S., Ed.; Ellis Horwood Ltd.: Chichester, 1990; pp 70-95.
    • (1990) Potassium Channels , pp. 70-95
    • Haylett, D.G.1    Jenkinson, D.H.2
  • 3
    • 0018849644 scopus 로고
    • A comparison between ATP and bradykinin as possible mediators of the responces of smooth muscle to non-adrenergic non-cholinergic nerves
    • Ferrero, J. D.; Cocks, T.; Burnstock, G. A comparison between ATP and bradykinin as possible mediators of the responces of smooth muscle to non-adrenergic non-cholinergic nerves. Eur. J. Pharmacol. 1980, 63, 295-302.
    • (1980) Eur. J. Pharmacol. , vol.63 , pp. 295-302
    • Ferrero, J.D.1    Cocks, T.2    Burnstock, G.3
  • 4
    • 0019395252 scopus 로고
    • 2 purinoceptor hypothesis in the guinea-pig taenia coli
    • 2 purinoceptor hypothesis in the guinea-pig taenia coli. Br. J. Pharmacol. 1981, 73, 617-624.
    • (1981) Br. J. Pharmacol. , vol.73 , pp. 617-624
    • Brown, C.M.1    Burnstock, G.2
  • 5
    • 0022345106 scopus 로고
    • Neuromuscular blocking agents inhibit receptor-mediated increases in the potassium permeability of intestinal smooth muscle
    • Gater, P. R.; Haylett, D. G.; Jenkinson, D. H. Neuromuscular blocking agents inhibit receptor-mediated increases in the potassium permeability of intestinal smooth muscle. Br. J. Pharmacol. 1985, 86, 861-868.
    • (1985) Br. J. Pharmacol. , vol.86 , pp. 861-868
    • Gater, P.R.1    Haylett, D.G.2    Jenkinson, D.H.3
  • 6
    • 0021080307 scopus 로고
    • Effects of apamin on α-adrenoceptor-mediated changes in plasma potassium in guinea-pigs
    • Coats, R. A. Effects of apamin on α-adrenoceptor-mediated changes in plasma potassium in guinea-pigs. Br. J. Pharmacol. 1983, 80, 573-580.
    • (1983) Br. J. Pharmacol. , vol.80 , pp. 573-580
    • Coats, R.A.1
  • 7
    • 0022404678 scopus 로고
    • The effects of adrenoceptor agonists and antagonists on plasma potassium concentration in anaesthetized guinea-pigs, rabbits and rats
    • Coats, R. A. The effects of adrenoceptor agonists and antagonists on plasma potassium concentration in anaesthetized guinea-pigs, rabbits and rats. Br. J. Pharmacol. 1985, 86, 827-836.
    • (1985) Br. J. Pharmacol. , vol.86 , pp. 827-836
    • Coats, R.A.1
  • 9
    • 0021288633 scopus 로고
    • + channel of the bullfrog sympathetic ganglion cell
    • + channel of the bullfrog sympathetic ganglion cell. Brain Res. 1984, 301, 146-148.
    • (1984) Brain Res. , vol.301 , pp. 146-148
    • Nohmi, M.1    Kuba, K.2
  • 11
    • 0023239672 scopus 로고
    • Apamin and d-tubocurarine block the afterhyperpolarizationof rat supraoptic neurosecretory neurons
    • Bourque, C. W.; Brown, D. A. Apamin and d-tubocurarine block the afterhyperpolarizationof rat supraoptic neurosecretory neurons. Neurosci. Lett. 1987, 82, 185-190.
    • (1987) Neurosci. Lett. , vol.82 , pp. 185-190
    • Bourque, C.W.1    Brown, D.A.2
  • 12
    • 0023089192 scopus 로고
    • Apamin depresses selectively the after-hyperpolarization of cat spinal motoneurons
    • Zhang, L.; Kmjevic, K. Apamin depresses selectively the after-hyperpolarization of cat spinal motoneurons. Neurosci. Lett. 1987, 74, 58-62.
    • (1987) Neurosci. Lett. , vol.74 , pp. 58-62
    • Zhang, L.1    Kmjevic, K.2
  • 14
    • 0019731426 scopus 로고
    • Effects of quinine and apamin on the calcium-dependent potassium permeability of mammalian hepatocytes and red cells
    • London
    • Burgess, G. M.; Claret, M.; Jenkinson, D. H. Effects of quinine and apamin on the calcium-dependent potassium permeability of mammalian hepatocytes and red cells. J. Physiol. (London) 1981, 317, 67-90.
    • (1981) J. Physiol. , vol.317 , pp. 67-90
    • Burgess, G.M.1    Claret, M.2    Jenkinson, D.H.3
  • 17
    • 0027468155 scopus 로고
    • Characterization of a new leiurotoxin I-like scorpion toxin PO5 from Androctonus mauretanicus mauretanicus
    • Zerrouk, H.; Mansuelle, P.; Benslimane, A.; Rochat, H.; Martin-Eauclaire, M. F. Characterization of a new leiurotoxin I-like scorpion toxin PO5 from Androctonus mauretanicus mauretanicus. FEBS Lett. 1993, 320, 189-192.
    • (1993) FEBS Lett. , vol.320 , pp. 189-192
    • Zerrouk, H.1    Mansuelle, P.2    Benslimane, A.3    Rochat, H.4    Martin-Eauclaire, M.F.5
  • 19
    • 0026803302 scopus 로고
    • Increase of apamin receptors in skeletal muscle induced by colchicine: Possible role in myotonia
    • Behrens, M. I.; Vergara, C. Increase of apamin receptors in skeletal muscle induced by colchicine: possible role in myotonia. Am. J. Physiol. 1992, 263, C974-C802.
    • (1992) Am. J. Physiol. , vol.263
    • Behrens, M.I.1    Vergara, C.2
  • 21
    • 0020646088 scopus 로고
    • 86Rb efflux and ethanol intoxication: Studies of human red blood cells and rodent brain synaptosomes
    • 86Rb efflux and ethanol intoxication: Studies of human red blood cells and rodent brain synaptosomes. Eur. J. Pharmacol. 1983, 88, 357-363.
    • (1983) Eur. J. Pharmacol. , vol.88 , pp. 357-363
    • Yamamoto, H.-A.1    Harris, R.A.2
  • 23
    • 0021895284 scopus 로고
    • Effects of apamin, quinine and neuromuscular blockers on calcium-activated potassium channels in guinea pig hepatocytes
    • Cook, N. S.; Haylett, D. G. Effects of apamin, quinine and neuromuscular blockers on calcium-activated potassium channels in guinea pig hepatocytes. J. Physiol. 1985, 358, 373-394.
    • (1985) J. Physiol. , vol.358 , pp. 373-394
    • Cook, N.S.1    Haylett, D.G.2
  • 24
    • 0021075057 scopus 로고
    • Calcium-activated Potassium channels in liver cells
    • Jenkinson, D. H.; Haylett, D. G.; Cook, N. S. Calcium-activated Potassium channels in liver cells. Cell Calcium 1983, 4, 429-437.
    • (1983) Cell Calcium , vol.4 , pp. 429-437
    • Jenkinson, D.H.1    Haylett, D.G.2    Cook, N.S.3
  • 26
    • 0027979644 scopus 로고
    • Dequalinium, a selective blocker of the slow afterhyperpolarization in rat sympathetic neurones in cultures
    • Dunn, P. M. Dequalinium, a selective blocker of the slow afterhyperpolarization in rat sympathetic neurones in cultures. Eur. J. Pharmacol. 1994, 252, 189-194.
    • (1994) Eur. J. Pharmacol. , vol.252 , pp. 189-194
    • Dunn, P.M.1
  • 27
    • 0007791473 scopus 로고
    • Potassium channel blocking activity of dequalinium analogues in guinea-pig hepatocytes and rat sympathetic neurones
    • Dunn, P. M.; Davis, C. A.; Ganellin, C. R.; Haylett, D. G.; Morgan, J. M.; Jenkinson, D. H. Potassium channel blocking activity of dequalinium analogues in guinea-pig hepatocytes and rat sympathetic neurones. Br. J. Pharmacol. 1991, 104, 165P.
    • (1991) Br. J. Pharmacol. , vol.104
    • Dunn, P.M.1    Davis, C.A.2    Ganellin, C.R.3    Haylett, D.G.4    Morgan, J.M.5    Jenkinson, D.H.6
  • 31
    • 5244316719 scopus 로고
    • Preparation of some N,N′-bis-(4-quinaldino)/(4-quinazolino)-α,ω- diaminialkanes(HCl) as potential antibacterial and antitubercular compounds
    • Deshpande, S. M.; Singh, A. K. Preparation of some N,N′-bis-(4-quinaldino)/(4-quinazolino)-α,ω- diaminialkanes(HCl) as potential antibacterial and antitubercular compounds. Agric. Biol. Chem. 1971, 35, 119-121.
    • (1971) Agric. Biol. Chem. , vol.35 , pp. 119-121
    • Deshpande, S.M.1    Singh, A.K.2
  • 32
    • 0016723968 scopus 로고
    • Antibacterial agents. III. Synthesis of N,N′-bis-(4-quinolinyl-, 4-quinaldinyl-, 4-quinazolinyl or 9-acridinyl)polymethylenediamines and their sulfonamides
    • Singh, A. K. Antibacterial agents. III. Synthesis of N,N′-bis-(4-quinolinyl-, 4-quinaldinyl-, 4-quinazolinyl or 9-acridinyl)polymethylenediamines and their sulfonamides. Chem. Pharm. Bull. 1975, 23, 1869-1873.
    • (1975) Chem. Pharm. Bull. , vol.23 , pp. 1869-1873
    • Singh, A.K.1
  • 33
    • 33947449429 scopus 로고
    • The role of phenol in the reaction of 4,7-dichloroquinoline with novol diamine
    • Surrey, A. R.; Cutler, R. K. The role of phenol in the reaction of 4,7-dichloroquinoline with novol diamine. J. Am. Chem. Soc. 1961, 73, 2623-2626.
    • (1961) J. Am. Chem. Soc. , vol.73 , pp. 2623-2626
    • Surrey, A.R.1    Cutler, R.K.2
  • 36
    • 1842691295 scopus 로고
    • Recent advances in the concept of hard and soft acids and bases
    • Pearson, R. G. Recent advances in the concept of hard and soft acids and bases. J. Chem. Ed. 1987, 64, 561-567.
    • (1987) J. Chem. Ed. , vol.64 , pp. 561-567
    • Pearson, R.G.1
  • 37
    • 0041919232 scopus 로고
    • The principle of maximum hardness
    • Pearson, R. G. The principle of maximum hardness. Acc. Chem. Res. 1993, 26, 250-255.
    • (1993) Acc. Chem. Res. , vol.26 , pp. 250-255
    • Pearson, R.G.1
  • 38
    • 3342943865 scopus 로고
    • Principle of maximum hardness
    • Parr, R. G.; Chattaraj, P. K. Principle of maximum hardness. J. Am. Chem. Soc. 1991, 113, 1854-1856.
    • (1991) J. Am. Chem. Soc. , vol.113 , pp. 1854-1856
    • Parr, R.G.1    Chattaraj, P.K.2
  • 39
    • 0027403280 scopus 로고
    • Primary structure and functional expression of a mouse inward rectifier potassium channel
    • Kubo, Y.; Baldwin, T. J.; Jan, Y. N.; Jan, L. Y. Primary structure and functional expression of a mouse inward rectifier potassium channel. Nature 1993, 362, 127-133.
    • (1993) Nature , vol.362 , pp. 127-133
    • Kubo, Y.1    Baldwin, T.J.2    Jan, Y.N.3    Jan, L.Y.4
  • 41
    • 0027161159 scopus 로고
    • mSlo, a Complex Mouse Gene Encoding "Maxi" Calcium-Activated Potassium Channels
    • Butler, A.; Tsunoda, S.; McCobb, D. P.; Wei, A.; Salkoff, L. mSlo, a Complex Mouse Gene Encoding "Maxi" Calcium-Activated Potassium Channels. Science 1993, 261, 221-224.
    • (1993) Science , vol.261 , pp. 221-224
    • Butler, A.1    Tsunoda, S.2    McCobb, D.P.3    Wei, A.4    Salkoff, L.5
  • 42
    • 0026689877 scopus 로고
    • - channel pharmacology
    • - channel pharmacology. Trends Pharmacol. Sci. 1992, 13, 359-365.
    • (1992) Trends Pharmacol. Sci. , vol.13 , pp. 359-365
    • Pongs, O.1
  • 43
    • 0027219695 scopus 로고
    • Primary structure and functional expression of a rat G protein-coupled muscarinic potassium channel
    • Kubo, Y.; Reuveny, E.; Slesinger, P. A.; Jan, Y. N.; Jan, L. Y. Primary structure and functional expression of a rat G protein-coupled muscarinic potassium channel. Nature 1993, 364, 802-806.
    • (1993) Nature , vol.364 , pp. 802-806
    • Kubo, Y.1    Reuveny, E.2    Slesinger, P.A.3    Jan, Y.N.4    Jan, L.Y.5
  • 46
    • 0004302015 scopus 로고    scopus 로고
    • Tripos Associates, Inc.: St. Louis, MO
    • Sybyl Molecular Modelling; Tripos Associates, Inc.: St. Louis, MO.
    • Sybyl Molecular Modelling
  • 47
    • 84988115618 scopus 로고
    • Validation of the general-purpose TRIPOS 5.2 force-field
    • Clark, M.; Cramer, R. D., III; Vann Opdenbosch, N. Validation of the general-purpose TRIPOS 5.2 force-field. J. Comput. Chem 1989, 10, 982-1012.
    • (1989) J. Comput. Chem , vol.10 , pp. 982-1012
    • Clark, M.1    Cramer III, R.D.2    Vann Opdenbosch, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.