Recombinant scinderin, an F-actin severing protein, increases calcium-induced release of serotonin from permeabilized platelets, an effect blocked by two scinderin-derived actin-binding peptides and phosphatidylinositol 4,5-bisphosphate

Blood

Volumn 87, Issue 1, 1996, Pages 20-24

  Marcu, Monica G ^a   Zhang, Li ^a   Nau Staudt, Kerstin ^a   Trifaró, José María ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN BINDING PROTEIN; CALCIUM ION; DIGITONIN; F ACTIN; GELSOLIN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; RECOMBINANT PROTEIN; RECOMBINANT SCINDERIN; SCINDERIN; SEROTONIN; THIOREDOXIN; UNCLASSIFIED DRUG;

ACTIN POLYMERIZATION; ARTICLE; BLOOD VESSEL INJURY; CHROMAFFIN CELL; DRUG EFFECT; EXOCYTOSIS; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; PSEUDOPODIUM; SEROTONIN RELEASE; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE RELEASE REACTION; THROMBOCYTE SHAPE;

ACTINS; AMINO ACID SEQUENCE; BINDING SITES; BLOOD PLATELETS; CALCIUM; CELL MEMBRANE PERMEABILITY; CLONING, MOLECULAR; DIGITONIN; DRUG SYNERGISM; EXOCYTOSIS; GELSOLIN; HUMANS; MICROFILAMENT PROTEINS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PLATELET ACTIVATION; RECOMBINANT FUSION PROTEINS; SEROTONIN;

EID: 0030029849     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.1.20.20     Document Type: Article

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