Automated multiple peptide synthesis: Improvements in obtaining quality peptides

International Journal of Peptide and Protein Research

Volumn 47, Issue 1-2, 1996, Pages 91-97

  Luu, Thong ^a   Pham, Son ^a   Deshpande, Shrikant ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Coupling solvent; Multiple peptide synthesis; Resin mixing; T cell epitopes

Indexed keywords

SYNTHETIC PEPTIDE;

ARTICLE; AUTOMATION; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG PURITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PEPTIDE SYNTHESIS; TECHNIQUE;

EID: 0030028775     PISSN: 03678377     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3011.1996.tb00814.x     Document Type: Article

References (17)

1. Merrifield, R.B. (1963) J. Am. Chem. Soc. 85, 2149-2154
2. Groginsky, C. (1990) Am. Biotech. Lab. 8, 40-43
3. Gausepohl, H., Boulin, C., Kraft, M. & Frank, R.W. (1992) Peptide Res. 5, 315-320
4. Arendt, A., McDowell, J.H. & Hargrave, P.A. (1993) Peptide Res. 6, 346-352
5. Beck-Sickinger, A.G., Durr, H. & Jung, G. (1991) Peptide Res. 4, 88-94.
6. Wolfe, H.R. & Wilk, R.R. (1989) Peptide Res. 2, 352-356
7. Narita, M. & Kojima Yoshihisa (1989) Bull. Chem. Soc. Jpn. 62, 3572-3576
8. Narita, M., Umeyama, H. & Yoshida, T. (1989) Bull Chem. Soc. Jpn. 62, 3577-3581
9. Fields, G.B. & Fields C.G. (1991) J. Am. Chem. Soc. 113, 4202-4207
10. Fields, C.G., Lloyd, D.H., Macdonald, R.L., Otteson, K.M. & Noble R.L. (1991) Peptide Res. 4, 95-101
11. Coste, J., Le-Nguyen, D. & Castro, B. (1990) Tetrahedron Lett. 31, 205-208
12. Live, D.H. & Kent, S.B.H. (1983) in Peptides: Structure and Function (Hruby, V.J. & Rich, D.H., eds.) pp. 65-68, Pierce Chem Co., Rockford, IL
13. Mutter, M., Altmann, K.-H., Bellof, D., Flörsheimer, A., Herbert, J., Huber, M., Klein, B., Strauch, L. & Vorherr, T. (1985) in Peptides: Structure and Function (Deber, V.J., Hurby, V.J. & Kopple, K.D., eds.) pp. 397-405, Pierce Chem Co., Rockford, IL
14. Ludwick, A.G., Jelinski, L.W., Live, D., Kintanar, A. & Dumias, J.J. (1986) J. Am. Chem. Soc. 108, 6493-6496
15. Fields, C.G., Fields, G.B., Noble, R.L. & Cross, T.A. (1989) Int. J. Peptide Protein Res. 33, 298-303
16. Atherton, E., Woolley, V. & Shepard, R.C. (1980) J. Chem. Soc., Chem. Commun. 970-971
17. Hyde, C., Johnson, T., Owen, D., Quibell, M. & Sheppard, R.C. (1994) Int. J. Peptide Protein Res. 43, 431-440