Strategies for manipulating apoptosis for cancer therapy with tumor necrosis factor and lymphotoxin

Journal of Cellular Biochemistry

Volumn 60, Issue 1, 1996, Pages 56-60

  Wong, G H W ^a   Kaspar, R L ^b   Zweiger, G ^b   Carlson, C ^b   Fong, S E ^b   Ehsani, N ^b   Vehar, G ^b  

^a GENENTECH INC   (United States)

^b NONE

Author keywords

apoptosis; Cancer; Fas; ICE proteases; LT; MnSOD; oxygen free radicals; radioprotection; radiosensitization; TNF

Indexed keywords

FAS ANTIGEN; LYMPHOTOXIN; PROTEINASE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CELL PROTECTION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RADIATION PROTECTION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; ENZYME INDUCTION; FAS LIGAND PROTEIN; HUMANS; LYMPHOTOXIN-ALPHA; MEMBRANE GLYCOPROTEINS; NEOPLASMS; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 0030028583     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19960101)60:1<56::AID-JCB9>3.0.CO;2-2     Document Type: Article

References (29)

1. Beutler B (1992): Tumor Necrosis Factors: The Molecules and Their Emerging Role in Medicine. New York: Raven Press.
2. Chinnaiyin A, O'Rourke K, Tewari M, Dixit V (1995); FADD, a novel domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 81:505.
3. Eddy LJ, Goeddel DV, Wong GH (1992): Tumor necrosis factor-alpha pretreatment is protective in a rat model of myocardial ischemia-reperfusion injury. Biochem Biophys Res Commun 184:1056-1059.
4. Enari M, Hug H, Nagata S (1995): Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature 375:78-81.
5. Hsu H, Xiong J, Goeddel D (1995): The TNF receptor1-associated protein TRADD signals cell death and NF-kappa B activation. Cell 81:495.
6. Itoh N, Yonehara S, Ishii A, Yonehara M, Mizushima S, Sameshima M, Hase A, Seto Y, Nagata S (1991): The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 66:233-243.
7. Kumar S, Baglioni C (1991): Protection from tumor necrosis factor-mediated cytolysis by overexpression of plasminogen activator inhibitor type-2. J Biol Chem 266:20960-20964.
8. Lichtenstein A, Gera JF, Andrews J, Berenson J, Ware CF (1991) Inhibitors of ADP-nbose polymerase decrease the resistance of HER2/neu-expressing cancer cells to the cytotoxic effects of tumor necrosis factor. J Immunol 146:2052-2058.
9. Liddil J, Door R, Scuderi P (1989): Association of lysosomal activity with sensitivity and resistance to tumor necrosis factor in murine L929 cells. Cancer Res 49:2772-2728.
10. Los M, Van de Craen M, Penning L, Schenk H, Westendorp M, Baeuerle P, Droge W, Krammer P, Fiers W, Schulze-Osthoff K (1995): Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis. Nature 375:81-83.
11. Martin S, Green D (1995): Protease activation during apoptosis: Death by a thousand cuts? Cell 82:349.
12. Miura M, Zhu H, Rotello R, Hartwieg EA, Yuan J (1993): Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C elegans cell death gene ced-3. Cell 75:653-660.
13. Neal M, Fiera A, Matthews N (1988): Involvement of phospholipase a2 activation in tumor cell killing by tumor necrosis factor. Immunology 64:81.
14. Nelson S, Wong G, McCord J (1995). Leukemia inhibitory factor and tumor necrosis factor induce manganese superoxide dismutase and protect rabbit hearts from reperfusion injury. J Mol Cell Cardiol 27:223-229.
15. Opipari AW Jr, Hu HM, Yabkowitz R, Dixit VM (1992): The A20 zinc finger protein protects cells from tumor necrosis factor cytotoxicity. J Biol Chem 267:12424-12427.
16. Sciavolino PJ, Lee TH, Vilcek J (1992): Overexpression of metallothionem confers resistance to the cytotoxic effect of TNF with cadmium in MCF-7 breast carcinoma cells. Lymphokine Cytokine Res 11:265-270.
17. Simon MM, Reikerstorfer A, Schwarz A, Krone C, Luger TA, Jaattela M, Schwarz T (1995): Heat shock protein 70 overexpression affects the response to ultraviolet light in murine fibroblasts. Evidence for increased cell viability and suppression of cytokine release. J Clin Invest 95:926-933.
18. Talley AK, Dewhurst S, Perry SW, Dollard SC, Gummuluru S, Fine SM, New D, Epstein LG, Gendelman HE, Gelbard HA (1995): Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA. Mol Cell Biol 15:2359-2366.
19. Tewari M, Dixit VM (1995): Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product. J Biol Chem 270:3255-3260.
20. Tewari M, Quan L, O'Rourke K, Desnoyers S, Zeng Z, Beidler D, Poirier G, Salvesen G, Dixit V (1995): Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly (ADP-ribose) polymerase. Cell 81:801.
21. Torti S, Kwak E, Miller S, Miller L, Ringold G, Myambo K, Young A, Torti F (1988): The molecular cloning and characterization of murine ferritin heavy chain, a tumor necrosis factor inducible gene. J Biol Chem 263:12638-12644.
22. Wong G (1995): Protective mechanisms of cytokines against oxidative stress: Induction of MnSOD: Nobel Symposium 90: Mitochondrial Diseases. Biochim Biophys Acta 205-209.
23. Wong G, Elwell J, Oberley L, Goeddel D (1989): Manganous superoxide dismutase is essential for cellular resistance to cytoxicity of tumor necrosis factor. Cell 58:923-931.
24. Wong G, Goeddel D (1988a): Induction of manganous superoxide dismutase by tumor necrosis factor: Possible protective mechanism. Science 242:941-944.
25. Wong G, Goeddel D (1988b): Tumor necrosis factors. Modulation of synthesis and biological activities. In Maini J, Dornand J (eds): "Lymphocyte Activation and Differentiation." New York: Walter de Gruyter, pp 217-226.
26. Wong GHW, McHugh T, Weber R, Goeddel, DV (1991): Tumor necrosis factor selectively sensitizes human immunodeficiency virus-infected cells to heat and radiation. Proc Natl Acad Sci USA 88:4372-4376.
27. Wong G, Kamb A, Tartaglia L, Goeddel D (1992a): Possible protective mechanisms of tumor necrosis factors against oxidative stress. "Molecular Biology of Free Radical Scavenging Systems." Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, pp 69-96.
28. Wong G, Neta R, Goeddel D (1992b): Protective roles of MnSOD, TNF-α, TNF-β, D-factor (LIF) in radiation injury. In Nigam S (ed): ''Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury" pp 353-357.
29. Wong GH, Goeddel DV (1994): Fas antigen and P55 TNF receptor signal apoptosis through distinct pathways. J Immunol 152.1751-1755.