Immunoregulatory effects of fas-mediated signalling

Journal of Cellular Biochemistry

Volumn 60, Issue 1, 1996, Pages 39-46

  Lynch, David H ^a   Alderson, Mark R ^a   Ramsdell, Fred ^a  

^a AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN;

ANTIBODY PRODUCTION; APOPTOSIS; ARTICLE; AUTOIMMUNITY; ETIOLOGY; GENE EXPRESSION REGULATION; GENETIC LINKAGE; GLOMERULONEPHRITIS; HUMAN; HUMAN CELL; IMMUNOREGULATION; LYMPHOCYTE SUBPOPULATION; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; FAS LIGAND PROTEIN; LIGANDS; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; T-LYMPHOCYTES;

EID: 0030028582     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19960101)60:1<39::AID-JCB7>3.0.CO;2-4     Document Type: Article

References (34)

1. Cohen PL, Eisenberg RA (1991): Lpr and gld: Single gene models of systemic autoimmunity and lymphoproliferative disease. Annu Rev Immunol 9:243-262.
2. Seldin MF, Morse III HC, Reeves JP, Scribner CL, LeBoeuf RC, Steinberg AD (1988): Genetic analysis of autoimmune gld mice. I. Identification of a restriction fragment length polymorphism closely linked to the gld mutation within a conserved linkage group. J Exp Med 167:688-693.
3. Watanabe T, Sakai Y, Mujawaki S, Shimizu A, Koiwai O, Ohno K (1991): A molecular genetic linkage map of mouse chromosome 19, including lpr, Lu44 and Tdt genes. Biochem Genet 29:325-335.
4. Watson ML, Eustachio PD, Mock BA, Steinberg AD, Morse HC, Oakley RJ, Howard TA, Rochelle JM, Seldin MF (1992): A linkage map of chromosome 1 using an interspecific cross segregating for the gld autoimmunity mutation. Mamm Genome 2:158-171.
5. Watson ML, Rao JK, Gilkeson GS, Ruiz P, Eicher EM, Pisetsky DS, Matsuzawa A, Rochelle JM, Seldin MF (1992): Genetic analysis of MKL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci. J Exp Med 176:1645-1656.
6. Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S (1992): Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356:314-317.
7. Smith CA, Farrah T, Goodwin RG (1994): The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death. Cell 75:959-962.
8. Adachi M, Watanabe-Fukunaga R, Nagata S (1993): Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice. Proc Natl Acad Sci USA 90:1756-1760.
9. Kobayashi S, Hirano T, Kakinuma M, Uede T (1993): Transcriptional repression and differential splicing of Fas mRNA by early transposon (ETn) insertion in autoimmune Ipr mice. Biochem Biophys Res Commun 191:617-624.
10. Allen RD, Marshall JD, Roths JB, Sidman CD (1990): Differences defined by bone marrow transplantation suggest that lpr and gld are mutations of genes encoding an interacting pair of molecules J Exp Med 172:1367-1375.
11. Ramsdell F, Seaman MS, Miller RE, Tough TW, Alderson MR, Lynch DH (1994): gld/gld mice are unable to express a functional ligand for Fas. Eur J Immunol 24:928-933.
12. Vignaux F, Golstein P (1994): Fas-based lymphocyte-mediated cytotoxicity against syngeneic activated lymphocytes: a regulatory pathway? Eur J Immunol 24:923-927.
13. Lynch DH, Watson ML, Alderson MR, Baum PR, Miller RE, Tough T, Gibson M, Davis-Smith T, Smith CA, Hunter K, Bhat D, Din W, Goodwin RG, Seldin MF (1994): The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster. Immunity 1:131-136.
14. Takahashi T, Tanaka M, Brannan CI, Jenkins NA, Copeland NG, Suda T, Nagata S (1994): Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76:969-976.
15. Trauth BC, Klas C, Peters AMJ, Matzku S, Möller P, Falk W, Debatin K-M, Krammer PH (1989): Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 245:301-305.
16. Yonehara S, Ishii A, Yonehara M (1989): A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J Exp Med 169:1747-1756.
17. Miyawaki T, Uehara T, Nibu R, Tsuji T, Yachie A, Yonehara S, Taniguchi N (1992): Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood. J Immunol 149:3753-3758.
18. Owen-Schaub LB, Yonehara S, Crump III WL, Grimm EA (1992): DNA fragmentation and cell death is selectively triggered in activated human lymphocytes by Fas antigen engagement. Cell Immunol 140:197-205.
19. Klas C, Debatin K-M, Jonker RR, Krammer PH (1993): Activation interferes with the APO-1 pathway in mature human T cells. Int Immunol 5:625-630.
20. Kriegler M, Perez C, DeFay K, Albert I, Lu SD (1988): A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: ramifications for the complex physiology of TNF Cell 53:45-53.
21. Goodwin RG, Alderson MR, Smith CA, Armitage RJ, VandenBos T, Jerzy R, Tough TW, Schoenborn MA, Davis-Smith T, Hennen K, Falk B, Cosman D, Baker E, Sutherland GR, Grabstein KH, Farrah T, Giri JG, Beckmann MP (1993): Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor. Cell 73:447-406.
22. Goodwin RG, Din WS, Davis-Smith T, Anderson DM, Gimpel SD, Sato TA, Maliszewski CR, Brannan CI, Copeland NG, Jenkins NA, Farrah T, Armitage RJ, Fanslow WC, Smith CA (1993): Molecular cloning of a ligand for the inducible T-cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor. Eur J Immunol 23:2631-2641.
23. Smith CA, Gruss H-J, Davis T, Anderson D, Farrah T, Baker E, Sutherland GR, Brannan CI, Copeland NG, Jenkins NA, Grabstein KH, Gliniak B, McAlister IB, Fanslow W, Alderson M, Falk B, Gimpel S, Gillis S, Din WS, Goodwin RG, Armitage RJ (1993): CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF Cell 73:1349-1360.
24. Armitage RJ, Fanslow WC, Strockbine L, Sato TA, Clifford KN, Macduff BM, Anderson DM, Gimpel SD, Davis-Smith T, Maliszewski CR, Clark EA, Smith CA, Grabstein KH, Cosman D, Spriggs MK (1992). Molecular and biological characterization of a murine ligand for CD40 Nature 357:80-82.
25. 2+-independent T cell-mediated cytotoxicity. J Exp Med 177:195-200.
26. Lynch DH, Miller RE (1994): Interleukin 7 promotes long-term in vitro growth of antitumor Cytotoxic T Lymphocytes with immunotherapeutic efficacy in vivo. J Exp Med 179:31-42.
27. Alderson MR, Tough TW, Braddy S, Davis-Smith T, Roux E, Schooley K, Miller RE, Lynch DH (1994): Regulation of apoptosis and T cell activation by Fas-specific mAb. Int Immunol 6:1799-1806.
28. Russell JH, Rush B, Weaver C, Wang R (1993): Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. Proc Natl Acad Sci USA 90:4409-4413.
29. Alderson MR, Tough TW, Davis-Smith T, Braddy S, Falk B, Schooley KA, Goodwin RG, Smith CA, Ramsdell F, Lynch DH (1995): Fas ligand mediates activation-induced cell death in human T lymphocytes. J Exp Med 181:71-77.30.
30. Dive C, Gregory CD, Phipps DJ, Evans DL, Milner AE, Wyllie AH (1992): Analysis and discrimination of necrosis and apoptosis (programmed cell death) by multiparameter flow cytometry. Biochim Biophys Acta 1133:275-285.
31. Alderson MR, Armitage RJ, Maraskovsky E, Tough TW, Roux E, Schooley K, Ramsdell F, Lynch DH (1993): Fas transduces activation signals in normal human T lymphocytes. J Exp Med 178:2231-2235.
32. Meyaard L, Otto SA, Jonker RR, Mijnster MJ, Keet RP, Miedema F (1992): Programmed death of T cells in HIV-1 infection. Science 257:217-219.
33. + T cells from human immunodeficiency virus-infected asymptomatic individuals. J Exp Med 175:331-340.
34. h2 cells to express Fas ligand and to undergo activation-induced cell death. Int Immunol 6:1545-1553.