Tauroconjugation of cholic acid stimulates 7α-dehydroxylation by fecal bacteria

Applied and Environmental Microbiology

Volumn 62, Issue 2, 1996, Pages 656-661

  Van Eldere, J ^a   Celis, P ^a   De Pauw, G ^a   Lesaffre, E ^b   Eyssen, H ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CHENODEOXYCHOLIC ACID; CHOLIC ACID; DEOXYCHOLIC ACID; FOLIC ACID; GLYCOCHOLIC ACID; HYDROGEN SULFIDE; PANTOTHENIC ACID; RIBOFLAVIN; SULFITE; TAURINE; TAUROCHOLIC ACID;

ARTICLE; BACTERIAL METABOLISM; BACTEROIDES; BILE ACID METABOLISM; CLOSTRIDIUM; CONJUGATION; FECES CULTURE; FECES MICROFLORA; HYDROXYLATION; INTESTINE FLORA; NONHUMAN;

EID: 0030028114     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/aem.62.2.656-661.1996     Document Type: Article

References (26)

1. Bak, F., and N. Pfennig. 1987. Chemolithotropic growth of Desulfovibrio sulfodismutans sp. nov. by disproportionation of inorganic sulfur compounds Arch. Microbiol. 147:184-189.
2. Coleman, J. P., W. B. White, B. Egestad, J. Sjövall, and P. B. Hylemon. 1987. Biosynthesis of a novel bile acid nucleotide and mechanism of 7α-dehydroxylation by an intestinal Eubacterium species. J. Biol. Chem. 262:4701-4707.
3. Dixon, W. J. 1990. BMDP statistical software manual, vol 2. University of California Press, Berkeley.
4. Elliott, W. H., L. B. Walsh, M. M. Mui, M. A. Thorne, and C. M. Siegfried. 1969. Bile acids XXVIII. Gas chromatography of new bile acids and their derivatives. J. Chromatogr. 44:452-464.
5. Franklund, C. V., S. F. Baron, and P. B. Hylemon. 1993. Characterization of the batH gene encoding a bile acid-inducible NADH: flavin oxidoreductase from Eubacterium sp. strain VPI 12708. J. Bacteriol. 175:3002-3012
6. Garbutt, J. T., L. Lack, and M. P. Tyor. 1971. Physiological basis of alterations in the relative conjugation of bile acids with glycine and taurine. Am. J Clin. Nutr. 24:218-228.
7. Goldin, B. R., L. Swenson, J. Dwyer, M. Sexton, and S. L. Gorbach. 1980. Effect of diet and Lactobacillus acidophilus supplements on human faecal bacterial enzymes. JNCI 64:255-261.
8. Hardison, W. G. M. 1978. Hepatic taurine concentration and dietary taurine as regulators of bile acid conjugation with taurine Gastroenterology 75:71-75.
9. Hill, M. J. 1985. Mechanisms of colorectal carcinogenesis, p. 149-163. In J. V. Joossens, M J. Hill, and J. Geboers (ed.), Diet and human carcinogenesis. Excerpta Medica, Amsterdam
10. Hirano, S., N. Masuda, and H. Oda. 1981. In vitro transformation of chenodeoxycholic acid and ursodeoxycholic acid by human intestinal flora, with particular reference to the mutual conversion between the two bile acids. J. Lipid Res 22:735-743
11. Holdeman, L. V., E. P. Cato, and W. E. C. Moore. 1977 Anaerobe laboratory manual, 4th ed. Virginia Polytechnic Institute and State University, Blacksburg, Va
12. Hylemon, P. B., and T. L. Glass. 1983. Biotransformation of bile acids and cholesterol by the intestinal microflora, p 190-213. In D. J. Hentges (ed). Human intestinal microflora in health and disease Academic Press, New York
13. Jacobsen, J. G., and L. H. Smith, Jr. 1968 Biochemistry and physiology of taurine and taurine derivatives Physiol. Rev 48:424-511
14. Macdonald, I. A., and D. M. Hutchison. 1982. Epimerization versus dehydroxylation of the 7α-hydroxyl group of primary bile acids competitive studies with Clostridium absonum and 7α-dehydroxylating bacteria (Eubacterium sp). J. Steroid Biochem. 17:295-303
15. Macdonald, I. A., G. Singh, D. E. Mahony, and C. E. Meier. 1978. Effect of pH on bile salt degradation by mixed faecal cultures Steroids 32:245-256.
16. Mallonee, D. H., J. L. Adams, and P. B. Hylemon. 1992 The bile acid-inducible batB gene from Eubacterium sp strain VPI 12708 encodes a bile acid-coenzyme A ligase J Bacteriol. 174:2065-2071
17. Miettinen, T. A. 1973. Clinical implications of bile acid metabolism in man, p. 191-247 In P. P. Nair and D. Kritchevsky (ed.). The bile acids. Chemistry, physiology and metabolism, volume 2 Physiology and metabolism Plenum Press, New York.
18. Ravi Subbiah, M. T., N. E. Tyler, M. D. Buscaglia, and L. Marai. 1976 Estimation of bile acid excretion in man: comparison of isotopic turnover and faecal excretion methods. J. Lipid Res. 17:78-84.
19. Samuelsson, B. 1960. Preparation of ursodeoxycholic acid and 3α,7β,12α-trihydroxycholanic acid. Acta Chem. Scand. 14:17-20.
20. Setoguchi, T., S. Higashi, S. Tateno, K. Yahiro, and T. Katsuki. 1984. Epimerization of the four 3,7-dihydroxy bile acid epimers by human faecal microorganisms in anaerobic mixed cultures and in feces. J. Lipid Res. 25:1246-1256.
21. Sjövall, J. 1959. Dietary glycine and taurine on bile acid conjugation in man. Bile acids and steroids 75. Proc. Soc. Exp. Biol. Med. 100:676-678.
22. Tannock, G. W. 1983. Effect of dietary and environmental stress on the gastrointestinal microbiota, p. 517-539. In D. J. Hentges (ed), Human intestinal microflora in health and disease. Academic Press, New York.
23. Taylor, W. 1971 The excretion of steroid hormone metabolites in bile and feces. Vitam. Horm. 29:201-285.
24. Van Eldere, J. 1988. Intestinal steroid desulfation. Leuven University Press, Leuven, Belgium. (Ph. D. thesis.)
25. Van Eldere, J., G. De Pauw, and H. J. Eyssen. 1987. Steroid sulfatase activity in a Peptococcus niger strain from the human intestinal microflora. Appl. Environ. Microbiol. 53:1655-1660.
26. Van Eldere, J., J. Robben, G. De Pauw, R. Merckx, and H. Eyssen. 1988. Isolation and identification of intestinal steroid-desulfating bacteria from rats and humans Appl. Environ Microbiol. 54:2112-2117.