Nuclear import of protein kinases and cyclins

Journal of Cellular Biochemistry

Volumn 60, Issue 1, 1996, Pages 61-82

  Boulikas, Teni ^a  

^a Inst of Molecular Medical Sciences   (United States)

Author keywords

acidic domains; cell cycle; cyclins; NLS; nuclear import; p34(cdc2); phosphatases; protein kinases

Indexed keywords

CARRIER PROTEIN; CYCLINE; PHOSPHATASE; PROTEIN KINASE;

ACTIVE TRANSPORT; ARTICLE; CELL NUCLEUS; ENZYME ACTIVITY; HUMAN; INTRACELLULAR TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TRANSPORT KINETICS;

AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL TRANSPORT; CELL CYCLE; CELL NUCLEUS; CYCLINS; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN KINASES;

ASTEROIDEA;

EID: 0030027917     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19960101)60:1<61::AID-JCB10>3.0.CO;2-N     Document Type: Article

References (109)

1. Ahn NG, Seger R, Bratlien RL, Diltz CD, Tonks NK, Krebs EG (1991): Multiple components in an epidermal growth factor-stimulated protein kinase cascade. In vitro activation of a myelin basic protein/microtubule-associated protein 2 kinase. J Biol Chem 266:4220-4227.
2. Alcorta DA, Crews CM, Sweet LJ, Bankston L, Jones SW, Erikson RL (1989): Sequence and expression of chicken and mouse rsk: homologs of Xenopus laevis ribosomal S6 kinase. Mol Cell Biol 9:3850-3859.
3. Anderson NG, Maller JL, Tonks NK, Sturgill TW (1990): Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase. Nature 343:651-653.
4. Beck TW, Huleihel M, Gunnell M, Blonner TI, Rapp UR (1987): The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-raf carrying retrovirus. Nucleic Acids Res 15:595-609.
5. 2+ calmodulin-dependent protein kinase determined by molecular cloning. Proc Natl Acad Sci U S A 84:1794-1798.
6. Bonner TI, Oppermann H, Seeburg P, Kerby SB, Gunnell MA, Young AC, Rapp UR (1986): The complete coding sequence of the human raf oncogene and the corresponding structure of the c-raf-1 gene. Nucleic Acids Res 14:1009-1015.
7. Boulikas T (1993): Nuclear localization signals (NLS). Crit Rev Eukar Gene Expression 3:193-227.
8. Boulikas T (1994a): Putative nuclear localization signals (NLS) in protein transcription factors. J Cell Biochem 55:32-58.
9. Boulikas T (1994b): A compilation and classification of DNA binding sites for protein transcription factors from vertebrates. Crit Rev Euk Gene Expression 4:137-321.
10. Boulikas T (1995): Phosphorylation of transcription factors and the control of the cell cycle. Eakar Gene Expression (In press).
11. Boulton TG, Yancopoulos GD, Gregory JS, Slaughter C, Moomaw C, Hsu J, Cobb MH (1990): An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control. Science 249:64-67.
12. Boyle WJ, Smeal T, Defize LHK, Angel P, Woodgett JR, Karin M, Hunter T (1991): Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity. Cell 64:573-584.
13. Breeden L, Nasmyth K (1987): Similarity between cell-cycle genes of budding yeast and fission yeast and the Notch gene of Drosophila. Nature 329:651-654.
14. Cannon JF, Tatchell K (1987): Characterization of Saccharomyces cerevisiae genes encoding subunits of cyclic AMP-dependent protein kinase. Mol Cell Biol 7:2653-2663.
15. Celenza JL, Carlson M (1986): A yeast gene that is essential for release from glucose repression encodes a protein kinase. Science 233:1175-1180.
16. Chamberlain JS, Van Tuinen P, Reeves AA, Philip BA, Caskey CT (1987): Isolation of cDNA clones for the catalytic γ-subunit of mouse muscle phosphorylase kinase: expression of mRNA in normal and mutant Phk mice. Proc Natl Acad Sci U S A 84:2886-2890.
17. Chan AM-L, King HWS, Tempest PR, Deakin EA, Cooper CS, Brookes P (1987): Primary structure of the met protein tyrosine kinase domain. Oncogene 1:229-233
18. Chen R-H, Sarnecki C, Blenis J (1992): Nuclear localization and regulation of erk- and rsk-encoded protein kinases. Mol Cell Biol 12:915-927.
19. Cherry JR, Johnson TR, Dollard C, Shuster JR, Denis CL (1989): Cyclic AMP-dependent protein kinase phosphorylates and inactivates the yeast transcriptional activator ADR1. Cell 56:409-419.
20. Cohen PTW, Brewis ND, Hughes V, Mann DJ (1990): Protein serine/threonine phosphatases; an expanding family. FEBS Lett 268:355-359.
21. Coussens L, Parker PJ, Rhee L, Yang-Feng TL, Chen E, Waterneid MD, Francke U, Ullrich A (1986a): Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signalling pathways. Science 233:859-866.
22. Coussens L, Van Beveren C, Smith D, Chen E, Mitchell RL, Isacke CM, Verma IM, Ullrich A (1986b): Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus. Nature 320:277-280.
23. Ebina Y, Ellis L, Jarnagin K, Edery M, Graf L, Clauser E, Ou J-h, Masiarz F, Kan YW, Goldfine ID, Roth RA, Rutter WJ (1985): The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling. Cell 40:747-758.
24. Edelman AM, Blumenthal DK, Krebs EG (1987): Protein serine-threonine kinases. Annu Rev Biochem 56:567-614.
25. Fu XY, Zhang JJ (1993): Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter. Cell 74:1135-1145.
26. Fu XY (1992): A transcription factor with SH2 and SH3 domains is directly activated by an interferon α-induced cytoplasmic protein tyrosine kinase(s). Cell 70:323-335.
27. Glass DB, Krebs EG (1979): Comparison of the substrate specificity of adenosine 3′:5′-monophosphate- and guanosine 3′:5′-monophosphate-dependent protein kinases. J Biol Chem 254:9728-9738.
28. Guerriero V, Russo MA, Olson NJ, Putkey JA, Means AR (1986). Domain organization of chicken gizzard myosin light chain kinase deduced from a cloned cDNA. Biochemistry 25:8372-8381.
29. 1 phase in yeast. Proc Natl Acad Sci U S A 86:6255-6259.
30. A) of the (Mg-ATP) dependent protein phosphatase. Eur J Biochem 119:443-451.
31. Hindley J, Phear GA (1984): Sequence of the cell division gene CDC2 from Schizosaccharomyces pombe; patterns of splicing and homology to protein kinases. Gene 31:129-134.
32. Huleihel M, Goldsborough M, Cleveland J, Gunnell M, Bonner T, Rapp UR (1986): Characterization of murine A-raf, a new oncogene related to the v-raf oncogene. Mol Cell Biol 6:2655-2662.
33. Hunter T, Karin M (1992): The regulation of transcription by phosphorylation. Cell 70:375-387.
34. Janknecht R, Hipskind RA, Houthaeve T, Nordheim A, Stunnenberg HG (1992): Identification of multiple SRF N-terminal phosphorylation sites affecting DNA binding properties. EMBO J 11:1045-1054.
35. Jones SW, Erikson E, Blenis J, Maller JL, Erikson RL (1988). A Xenopus ribosomal protein S6 kinase has two apparent kinase domains that are each similar to distinct protein kinases. Proc Natl Acad Sci U S A 85:3377-3381.
36. Knopf JL, Lee M-H, Sultzman LA, Kriz RW, Loomis CR, Hewick RM, Bell RB (1986): Cloning and expression of multiple protein kinase C cDNAs. Cell 46:491-502.
37. Koch CA, Anderson D, Moran MF, Ellis C, Pawson T (1991): SH2 and SH3 domains: elements that control interactions of cytoplasmic signalling proteins. Science 252:668-674.
38. Koff A, Cross F, Fisher A, Shumacher J, Leguellec K, Philippe M, Roberts JM (1991): Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family. Cell 66:1217-1228.
39. Krek W, Maridor G, Nigg EA (1992): Casein kinase II is a predominantly nuclear enzyme. J Cell Biol 116:43-55.
40. Kyriakis JM, App H, Zhang X, Banerjee P, Brautigan DL, Rapp UR, Avruch J (1992): Raf-1 activates MAP kinase-kinase. Nature 358:417-421
41. Leach KL, Powers EA, Ruff VA, Jaken S, Kaufmann S (1989): Type 3 protein kinase C localization to the nuclear envelope of phorbol ester-treated NIH 3T3 cells. J Cell Biol 109:685-695.
42. Lee JM, Greenleaf AL (1991): CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae. Gene Expression 1:149-167.
43. Lee MG, Nurse P (1987): Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2. Nature 327:31-35.
44. Lee W-C, Xue Z, Mélèse T (1991): The NSR1 gene encodes a protein that specifically binds nuclear localization sequences and has two RNA recognition motifs. J Cell Biol 113:1-12.
45. Lehner CF, O'Farrel PH (1989): Expression and function of Drosophila cyclin A during embryonic cell cycle development. Cell 56:957-968
46. Levin DE, Hammond CI, Ralston RO, Bishop JM (1987): Two yeast genes that encode unusual protein kinases. Proc Natl Acad Sci 84:6035-6039.
47. Lin A, Frost J, Deng T, Smeal T, Al-Alawi N, Kikkawa U, Hunter T, Brenner D, Karin M (1992): Casein kinase II is a negative regulator of c-Jun DNA binding and AP-activity. Cell 70:777-789.
48. Lin CR, Kapiloff MS, Durgerian S, Tatemoto K, Russo A, Hanson P, Schulman H, Rosenfeld MG (1987): Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase. Proc Natl Acad Sci U S A 84:5962-5966.
49. Lisziewicz J, Godany A, Forster HH, Kuntzel H (1986): Isolation and nucleotide sequences of a Saccharomyces cerevisiae protein kinase gene suppressing the cell cycle start mutation cdc25. J Biol Chem 262:2549-2553.
50. Lörincz AT, Reed SI (1984): Primary structure homology between the product of yeast cell division control gene CDC28 and vertebrate oncogenes. Nature 307:183-185.
51. Mark GE, Rapp UR (1984): Primary structure of v-raf: relatedness to the src family of oncogenes. Science 224:285-289.
52. Mark GE, Seeley TW, Shows TB, Mountz JD (1986): pks, a raf-related sequence in humans. Proc Natl Acad Sci U S A 83:6312-6316.
53. Martinage A, Mangeat P, Laine B, Couppez M, Sautiere P, Marchis-Mouren G, Biserte G (1980): In vitro phosphorylation of histones H5, H2A, H2B and of the dimer H2A-H2B by a cyclic AMP-dependent protein kinase from rat pancreas. FEBS Lett 118:323-329.
54. Matsushime H, Wang LH, Shibuya M (1986): Human c-ros-1 gene homologous to the v-ros sequence of UR2 sarcoma virus encodes for a transmembrane receptorlike molecule. Mol Cell Biol 6:3000-3004.
55. Mazzanti M, DeFelice LJ, Cohen J, Malter H (1990): Ion channels in the nuclear envelope. Nature 343:764-767.
56. Meier UT, Blobel G (1992): Nopp140 shuttles on tracks between nucleolus and cytoplasm. Cell 70:127-138.
57. Metz R, Ziff E (1991): cAMP stimulates the C/EBP-related transcription factor rNFIL-6 to trans-locate to the nucleus and induce c-fos transcription. Genes Dev 5:1754-1766.
58. Meyerson M, Enders GH, Wu C-L, Su L-K, Gorka C, Nelson C, Harlow E, Tsai L-H (1992): A family of human cdc2-related protein kinases. EMBO J 11:2909-2917.
59. Mudryj M, Devoto SH, Hiebert SW, Hunter T, Pines J, Nevins JR (1991): Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A. Cell 65:1243-1253.
60. Minshull J, Blow JJ, Hunt T (1989): Translation of cyclin mRNA is necessary for extracts of activated Xenopus eggs to enter mitosis Cell 56:947-956.
61. Nigg EA, Hitz H, Eppenberger HM, Dutly F (1985): Rapid and reversible translocation of the catalytic subunit of cAMP-dependent protein kinase type II from the Golgi complex to the nucleus. EMBO J 4:2801-2806.
62. Ninomiya-Tsuji J, Nomoto S, Yasuda H, Reed SI, Matsumoto K (1991): Cloning of a human cDNA encoding a CDC2-related kinase by complementation of a budding yeast cdc28 mutation. Proc Natl Acad Sci U S A 88:9006-9010.
63. Ohno S, Kawasaki H, Imajoh S, Suzuki K, Inagaki M, Yokokura H, Sakoh T, Hidaka H (1987): Tissue-specific expression of three distinct types of rabbit protein kinase C. Nature 325:161-166.
64. Paris J, Le Guellec R, Couturier A, Le Guellec K, Omilli F, Camonis J, MacNeil S, Philippe M (1991): Cloning by differential screening of a Xenopus cDNA coding for a protein highly homologous to cdc2. Proc Natl Acad Sci U S A 88:1039-1043.
65. Park M, Dean M, Kaul K, Braun MJ, Gonda MA, Vande Woude G (1987): Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors. Proc Natl Acad Sci U S A 84:6379-6383.
66. Parker PJ, Coussens L, Totty N, Rhee L, Young S, Chen E, Stabel S, Waterfield MD, Ullrich A (1986): The complete primary structure of protein kinase C - the major phorbol ester receptor. Science 233:853-859.
67. Patterson M, Sclafani RA, Fangman WL, Rosamond J (1986): Molecular characterization of cell cycle gene CDC7 from Saccaromyces cerevisiae. Mol Cel Biol 6:1590-1598.
68. cdc2. Cell 58:833-846.
69. Posada J, Sanghera J, Pelech S, Aebersold R, Cooper JA (1991): Tyrosine phosphorylation and activation of homologous protein kinases during oocyte maturation and mitogenic activation of fibroblasts. Mol Cell Biol 11:2517-2528.
70. Reimann EM, Titani K, Ericsson LH, Wade RD, Fischer EH, Walsh KA (1984): Homology of the γ subunit of phosphorylase b kinase with cAMP-dependent protein kinase. Biochemistry 23:4185-4192.
71. Rosenthal A, Rhee L, Yadegari R, Paro R, Ullrich A, Goeddel DV (1987): Structure and nucleotide sequence of a Drosophila melanogaster protein kinase C gene. EMBO J 6:433-441.
72. -, a gene encoding a protein kinase homolog. Cell 49:559-567.
73. Saxena A, Padmanabha R, Glover CVC (1987): Isolation and sequencing of cDNA clones encoding alpha and beta subunits of Drosophila melanogaster casein kinase II. Mol Cell Biol 7:3409-3417.
74. Sheng M, McFadden G, Greenberg ME (1990): Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB. Neuron 4:571-582.
75. 2--regulated transcription factor phosphorylated by calmodulin-dependent kinases. Science 252:1427-1430.
76. Shoji S, Parmelee DC, Wade RD, Kumar S, Ericsson LH, Walsh KA, Neurath H, Long GL, DeMaille JG, Fischer EH, Titani K (1981): Complete amino acid sequence of the catalytic subunit of bovine cardiac muscle cyclic AMP-dependent protein kinase. Proc Natl Acad Sci U S A 78:848-851.
77. Showers MO, Maurer RA (1986): A cloned bovine cDNA encodes an alternate form of the cayalytic subunit of cAMP-dependent protein kinase. J Biol Chem 261:16288-16291.
78. Shtivelman E, Lifshitz B, Gale RP, Roe BA, Canaani E (1986): Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene. Cell 47:277-284.
79. Shuai KE, Ziemicki A, Wilks AF, Harpur AG, Sadowski HB, Gilman MZ, Darnell JE (1993): Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins. Nature 366:580-583.
80. Siegfried E, Perkins LA, Capaci TM, Perrimon N (1990): Putative protein kinase product of the Drosophila segment-polarity gene zeste-white 3. Nature 345:825-829.
81. Simon M, Seraphin B, Faye G (1986): KIN28, a yeast split gene coding for a putative protein kinase homologous to CDC28. EMBO J 5:2697-2701.
82. Sukegawa J, Semba K, Yamanashi Y, Nishizawa M, Miyajima N, Yamamoto T, Toyoshima K (1987): Characterization of cDNA clones for the human c-yes gene. Mol Cell Biol 7:41-47.
83. Swenson KI, Farrell KM, Ruderman JV (1986): The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes. Cell 47:861-870.
84. Takahashi M, Cooper GM (1987): ret transforming gene encodes a fusion protein homologous to tyrosine kinases. Mol Cell Biol 7:1378-1385.
85. Takeya T, Hanafusa H (1983): Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus. Cell 32:881-890.
86. Takio K, Blumenthal DK, Edelman AM, Walsh KA, Krebs EG, Titani K (1985): Amino acid sequence of an active fragment of rabbit skeletal muscle myosin light chain kinase. Biochemistry 24:6028-6037.
87. Takio K, Kuenzel EA, Walsh KA, Krebs EG (1987): Amino acid sequence of the β subunit of bovine lung casein kinase II. Proc Natl Acad Sci U S A 84:4851-4855.
88. Takio K, Wade RD, Smith SB, Krebs EG, Walsh KA, Titani K (1984): Guanosine cyclic 3′,5′-phosphate dependent protein kinase, a chimeric protein homologous with two separate protein families. Biochemistry 23:4207-4218.
89. Tamura S, Lynch KR, Larner J, Fox J, Yasui A, Kikuchi K, Suzuki Y, Tsuiki S (1989): Molecular cloning of rat type 2C (IA) protein phosphatase mRNA. Proc Natl Acad Sci U S A 86:1796-1800.
90. Teague MA, Chaieff DT, Errede B (1986): Nucleotide sequence of the yeast regulatory gene STE7 predicts a protein homologous to protein kinases. Proc Natl Acad Sci U S A 83:7371-7375.
91. Toda T, Cameron S, Sass P, Zoller M, Wigler M (1987): Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell 50:277-287.
92. Tratner I, Ofir R, Verma IM (1992): Alteration of a cyclic AMP-dependent protein kinase phosphorylation site in c-Fos protein augments its transforming potential. Mol Cell Biol 12:998-1006.
93. Tsai L-H, Harlow E, Meyerson M (1991): Isolation of the human cdk2 gene that encodes the cychn A- and adenovirus E1A-associated p33 kinase. Nature 353:174-177.
94. Uhler MD, Carmichael DF, Lee DC, Chrivia JC, Krebs EG, McKnight GS (1986a): Isolation of cDNA clones coding for the catalytic subunit of mouse cAMP-dependent protein kinase. Proc Natl Acad Sci U S A 83:1300-1304.
95. Uhler MD, Chrivia JC, McKnight GS (1986b): Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase. J Biol Chem 261:15360-15363.
96. Ullrich A, Bell JR, Chen EY, Herrera R, Petruzzelli LM, Dull TJ, Gray A, Coussens L, Liao Y-C, Tsubokawa M, Mason A, Seeburg PH, Grunfeld C, Rosen OM, Ramachandran J (1985): Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes. Nature 313:756-761.
97. Ullrich A, Cousens L, Hayflick JS, Dull TJ, Gray A, Tam AW, Lee J, Yarden Y, Libermann TA, Schlessinger J, Downward J, Mayes ELV, Whittle N, Waterfeld MD, Seeburg PH (1984): Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature 309:418-425.
98. van Beveren C, van Straaten F, Galleshaw JA, Verma IM (1981a): Nucleotide sequence of the genome of a murine sarcoma virus. Cell 27:97-108.
99. van Beveren C, Galleshaw JA, Jonas V, Berns AJM, Doolittle RF, Donoghue DJ, Verma IM (1981b): Nucleotide sequence and formation of the transforming gene of a mouse sarcoma virus. Nature 289:258-262.
100. van der Hoorn FA, Firzlaff J (1984): Complete c-mos (rat) nucleotide sequence: presence of conserved 2 domains in c-mos proteins. Nucleic Acids Res 12:2147-2156.
101. Velazquez L, Fellous M, Stark GR, Pellegrini S (1992): A protein tyrosine kinase in the Interferon α/β signaling pathway. Cell 70:313-322.
102. Voronova AF, Sefton BM (1986): Expression of a new tyrosine protein kinase is stimulated by retrovirus promoter insertion. Nature 319:682-685.
103. Wang J, Chenivesse X, Henglein B, Bréchot C (1990): Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma. Nature 343:555-557.
104. Watson R, Oskarsson M, Vande Woude GF (1982): Human DNA sequence homologous to the transforming gene (mos) of Moloney murine sarcoma virus. Proc Natl Acad Sci U S A 79:4078-4082.
105. Woodgett JR (1990): Molecular cloning and expression of glycogen synthase kinase-3/factor A. EMBO J 9:2431-2438.
106. Woodgett JR (1991): A common denominator linking glycogen metabolism, nuclear oncogenes and development. Trends Biol Sci 16:177-181.
107. Xiong Y, Connolly T, Futcher B, Beach D (1991): Human D-type cyclin. Cell 65:691-699.
108. lck. Mol Cell Biol 7:237-243.
109. Yarden Y, Kuang W-J, Yang-Feng T, Coussens L, Munemitsu S, Dull TJ, Chen E, Schlessinger J, Francke U, Ullrich A (1987): Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified region. EMBO J 6:3341-3351.