IL-10-driven immunoglobulin production by B lymphocytes from IgA-deficient individuals correlates to infection proneness

Clinical and Experimental Immunology

Volumn 104, Issue 3, 1996, Pages 432-438

  Friman, V ^a,c   Hanson, L A ^a   Bridon, J M ^b   Tarkowski, A ^a   Banchereau, J ^d   Briere F ^b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b MERCK RESEARCH LABORATORIES   (United States)

^c SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^d NONE

Author keywords

B lymphocytes; CD40; IgA deficiency; IL 10; Immunoglobulin production

Indexed keywords

CD40 ANTIGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN A1; IMMUNOGLOBULIN A2; INTERLEUKIN 10;

ADULT; ARTICLE; B LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; IMMUNOGLOBULIN A DEFICIENCY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; MALE; PHENOTYPE; PRIORITY JOURNAL;

EID: 0030027870     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1996.38746.x     Document Type: Article

References (40)

1. Ammann AJ, Hong R. Selective IgA deficiency: presentation of 30 cases and a review of the literature. Medicine 1971; 50:223-36.
2. Hanson LÅ, Björkander J, Oxelius V-A. Selective IgA deficiency. In: Chandra RK, ed. Primary and secondary immunodeficiency disorders. Edinburgh: Churchill Livingstone, 1983:62-84.
3. Koistinen J. Selective IgA deficiency in blood donors. Vox Sang 1975; 29:192-202.
4. Brandtzaeg P, Karlsson G, Hansson G, Petrusson B, Björkander J, Hanson LÅ. The clinical condition of IgA-deficient patients is related to the proportion of IgD- and IgM-producing cells in their nasal mucosa. Clin Exp Immunol 1987; 67:626-36.
5. Mellander L, Björkander J, Carlsson B, Hanson LÅ. Secretory antibodies in IgA-deficient and immunosuppressed individuals. J Clin Immunol 1986; 6:284-91.
6. Norhagen EG, Engström P-E, Hammarström L, Söder P-Ö, Smith CIE. Immunoglobulin levels in saliva in individuals with selective IgA deficiency: compensatory IgM secretion and its correlation with HLA and susceptibility to infections. J Clin Immunol 1989; 9:279-86.
7. Friman V, Quiding M, Czerkinsky C et al. Intestinal and circulating antibody-forming cells in IgA-deficient individuals after oral cholera vaccination. Clin Exp Immunol 1994; 95:222-6.
8. Cassidy JT, Oldham G, Platts-Mills TAE. Functional assessment of a B cell defect in patients with selective IgA deficiency. Clin Exp Immunol 1979; 35:296-305.
9. Islam KB, Baskin B, Christensson B, Hammarström L, Smith CIE. In vivo expression of human immunoglobulin germ-line mRNA in normal and in immunodeficient individuals. Clin Exp Immunol 1994; 95:3-9.
10. Islam KB, Baskin B, Nilsson L, Hammarström L, Sideras P, Smith CIE. Molecular analysis of IgA deficiency. Evidence for impaired switching to IgA. J Immunol 1994; 152:1442-52.
11. Waldmann TA, Broder S, Krakauer R, Durm M, Meade B, Goldman C. Defects in IgA secretion and in IgA specific suppressor cells in patients with selective IgA deficiency. Trans Assoc Am Phys 1976; 89:215-24.
12. Atwater JS, Tomasi TB Jr. Supressor cells and IgA deficiency. Clin Immunol Immunopathol 1978; 9:379-84.
13. King MA, Wells JV, Nelson DS. IgA synthesis by peripheral blood mononuclear cells from normal and selectively IgA deficient subjects. Clin Exp Immunol 1979; 38:306-15.
14. Banchereau J, de Paoli P, Vallé A, Garcia E, Rousset F. Long-term human B cell lines dependent on interleukin-4 and antibody to CD40. Science 1991; 251:70-72.
15. Rousset F, Garcia E, Banchereau J. Cytokine-induced proliferation and immunoglobulin production of human B lymphocytes triggered through their CD40 antigen. J Exp Med 1991; 173:705-10.
16. Armitage RJ, Macduff BM, Spriggs MK, Fanslow WC. Human B cell proliferation and Ig secretion induced by recombinant CD40 ligand are modulated by soluble cytokines. J Immunol 1993; 150:367-80.
17. Rousset F, Garcia E, Defrance T et al. Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc Natl Acad Sci USA 1992; 89:1890-3.
18. Vallé A, Zuber CE, Defrance T, Djossou O, De Rie M, Banchereau J. Activation of human B lymphocytes through CD40 and interleukin 4. Eur J Immunol 1989; 19:1463-7.
19. Defrance T, Vanbervliet B, Brière F, Durand I, Rousset F, Banchereau J. Interleukin 10 and transforming growth factor β cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A. J Exp Med 1992; 175:671-82.
20. Nonoyama S, Farrington M, Ishida H, Howard M, Ochs HD. Activated B cells from patients with common variable immunodeficiency proliferate and synthesize immunoglobulin. J Clin Invest 1993; 92:1282-7.
21. Zielen S, Bauscher D, Hofmann D, Meuer SC. Interleukin 10 and immune restoration in common variable immunodeficiency. Lancet 1993; 342:750-1.
22. Eisenstein EM, Chua K, Strober W. B cell differentiation defects in common variable immunodeficiency are ameliorated after stimulation with anti-CD40 antibody and IL-10. J Immunol 1994; 152:5957-68.
23. Brière F, Bridon J-M, Chevet D et al. Interleukin 10 induces B lymphocytes from IgA-deficient patients to secrete IgA. J Clin Invest 1994; 94:97-104.
24. Oxelius V-A. IgG subclass levels in infancy and childhood. Acta Paediatr Scand 1979; 68:23-27.
25. Peltz GA, Trounstine ML, Moore KW. Cloned and expressed human Fc receptor for IgG mediates anti-CD3-dependent lympho-proliferation. J Immunol 1988; 141:1891-6.
26. Lea T, Vartdul F, Davies C, Ugelstad J. Magnetic monosized polymer particles for fast and specific fractionation of human mononuclear cells. Scand J Immunol 1985; 22:207-16.
27. Chrétien I, Pène J, Brière F, De Waal Malefÿt R, Rousset F, De Vries JE. Regulation of human IgE synthesis. I. Human IgE synthesis in vitro is determined by the reciprocal antagonistic effects of IL-4 and IFN-γ. Eur J Immunol 1990; 20:243-51.
28. Mancini, G, Carbonara AO, Heremans JF. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry 1965; 2:235-54.
29. Hammarström L, Smith CIE. HLA-A, B, C and DR antigens in immunoglobulin A deficiency. Tissue Antigens 1983; 21:75-79.
30. Schaffer FM, Palermos J, Zhu ZB, Barger BO, Cooper MD, Volanakis JE. Individuals with IgA deficiency and common variable immunodeficiency share polymorphisms of major histocompatibility complex class III genes. Proc Natl Acad Sci USA 1989; 86:8015-9.
31. Olerup O, Smith CIE, Hammarström L. Different amino acids at position 57 of the HLA-DQβ chain associated with susceptibility and resistance to IgA deficiency. Nature 1990; 347:289-90.
32. Lawton AR, Stuart A, Royal SA, Self KS, Cooper MD. IgA determinants on B-lymphocytes in patients with deficiency of circulating IgA. J Lab Clin Med 1972; 80:26-33.
33. Oen K, Schroeder ML, Krzekotowska D. Pokeweed mitogen and Staphyloccoccus aureus Cowan I induced immunoglobulin A synthesis by lymphocytes of IgA-deficient blood donors. Clin Exp Immunol 1985; 62:387-96.
34. Conley MF, Cooper MD. Immature IgA B cells in IgA-delicient patients. N Eng J Med 1981; 305:495-7.
35. Wu LYF, Lawton AR, Cooper MD. Differentiation capacity of cultured B lymphocytes from immunodeficient patients. J Clin Invest 1973; 52:3180-9.
36. Luzi G, Kubagawa H, Crain MJ, Cooper MD. Analysis of IgG subclass production in cell cultures from IgA deficient patients and in normal controls as a function of age. Clin Exp Immunol 1986; 65:434-42.
37. Burdin N, Van Kooten C, Galibert L, Abrams JS, Wijdenes J, Banchereau J, Rousset F. Endogenous IL-6 and IL-10 contribute to differentiation of CD40-activated human B lymphocytes. J Immunol 1995; 154:2533-44.
38. Ramsay AJ, Husband AJ, Ramshaw IA, Bao S, Matthaei KI, Koehler G, Kopf M. The role of interleukin-6 in mucosal IgA antibody responses in vivo. Science 1994; 264:561-3.
39. French MAH, Denis KA, Dawkins R, Peter JB. Severity of infections in IgA deficiency: correlation with decreased serum antibodies to pneumococcal polysaccharides and decreased serum IgG2 and or IgG4. Clin Exp Immunol 1995; 100:47-53.
40. Grossman CJ. Interactions between the gonadal steroids and the immune system. Science 1985; 227:257-61.