Biotransformation of lifibrol (U-83860) to mixed glyceride metabolites by rat and human hepatocytes in primary culture

Drug Metabolism and Disposition

Volumn 24, Issue 2, 1996, Pages 221-231

  Sun, E L ^a   Feenstra, K L ^a   Bell, F P ^a   Sanders, P E ^a   Slatter, J G ^a   Ulrich, R G ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [2 HYDROXY 4 [4 (2 HYDROXY 1,1 DIMETHYLETHYL)PHENYL]BUTOXY]BENZOIC ACID; 4 [4 [4 (2 CARBOXY 1,1 DIMETHYLETHYL)PHENYL] 2 HYDROXYBUTOXY]BENZOIC ACID; ACETIC ACID; ANTILIPEMIC AGENT; CARBON 14; DRUG METABOLITE; LIFIBROL; U 94613; U 94614; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; DRUG TRANSFORMATION; DRUG UPTAKE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYPERLIPIDEMIA; LIPOPHILICITY; LIVER CELL CULTURE; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; RADIOACTIVITY; RAT;

ANIMALS; ANTICHOLESTEREMIC AGENTS; BIOTRANSFORMATION; BUTANOLS; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CULTURE MEDIA; GLYCERIDES; HUMANS; HYDROXYBENZOIC ACIDS; LIVER; MALE; MASS SPECTROMETRY; MOLECULAR STRUCTURE; RADIOLIGAND ASSAY; RATS; RATS, WISTAR;

EID: 0030027819     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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