6,7-disubstituted 2,4-diaminopteridines: Novel inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase

Antimicrobial Agents and Chemotherapy

Volumn 40, Issue 6, 1996, Pages 1371-1375

  Jackson, Helen C ^a,d   Biggadike, Keith ^a   McKilligin, Elaine ^a   Kinsman, Oonagh S ^a   Queener, Sherry F ^c   Lane, Amanda ^b   Smith, Judith E ^b  

^a GLAXOSMITHKLINE   (United Kingdom)

^b UNIVERSITY OF LEEDS   (United Kingdom)

^c INDIANA UNIVERSITY   (United States)

^d MEDIMMUNE LTD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DIAMINO 6,7 DIISOBUTYLPTERIDINE; 2,4 DIAMINO 6,7 DIISOPROPYLPTERIDINE; 2,4 DIAMINO 7 ETHYL 6 (2 METHOXYPHENYL)PTERIDINE; 4 AMINOBENZOIC ACID; AH 2504; DIHYDROFOLATE REDUCTASE INHIBITOR; FOLIC ACID ANTAGONIST; GR 92754; PTERIDINE DERIVATIVE; PYRIMETHAMINE; TRIMETHOPRIM; TRIMETREXATE GLUCURONATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; ENZYME INHIBITION; KIDNEY CELL; MALE; NONHUMAN; PNEUMOCYSTIS CARINII; PRIORITY JOURNAL; RAT; TOXOPLASMA GONDII;

EID: 0030027555     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.40.6.1371     Document Type: Article

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